JP6847044B2 - 肥満及び２型糖尿病（ｔ２ｄ）の治療のための膵内分泌前駆細胞療法 - Google Patents

肥満及び２型糖尿病（ｔ２ｄ）の治療のための膵内分泌前駆細胞療法 Download PDF

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JP6847044B2
JP6847044B2 JP2017547514A JP2017547514A JP6847044B2 JP 6847044 B2 JP6847044 B2 JP 6847044B2 JP 2017547514 A JP2017547514 A JP 2017547514A JP 2017547514 A JP2017547514 A JP 2017547514A JP 6847044 B2 JP6847044 B2 JP 6847044B2
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ティモシー・ジェイ・キーファー
ジェニファー・イー・ブルーイン
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シーシーエス・ベンチャーズ・リミテッド
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells

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JP2017547514A 2015-03-11 2016-03-11 肥満及び２型糖尿病（ｔ２ｄ）の治療のための膵内分泌前駆細胞療法 Active JP6847044B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562131540P 2015-03-11 2015-03-11
US62/131,540 2015-03-11
PCT/CA2016/000072 WO2016141460A1 (en) 2015-03-11 2016-03-11 Pancreatic endocrine progenitor cell therapies for the treatment of obesity and type 2 diabetes (t2d)

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JP2018507889A JP2018507889A (ja) 2018-03-22
JP2018507889A5 JP2018507889A5 (cg-RX-API-DMAC7.html) 2019-04-18
JP6847044B2 true JP6847044B2 (ja) 2021-03-24

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US (2) US10772917B2 (cg-RX-API-DMAC7.html)
EP (1) EP3268016B1 (cg-RX-API-DMAC7.html)
JP (1) JP6847044B2 (cg-RX-API-DMAC7.html)
CN (1) CN107530379A (cg-RX-API-DMAC7.html)
AU (1) AU2016228894B2 (cg-RX-API-DMAC7.html)
CA (1) CA2979293C (cg-RX-API-DMAC7.html)
WO (1) WO2016141460A1 (cg-RX-API-DMAC7.html)

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WO2019118641A1 (en) * 2017-12-12 2019-06-20 The Regents Of The University Of California Preservation of pancreatic islet grafts in the extrahepatic space
EP3741757B1 (en) 2018-01-18 2023-07-26 Daiichi Sankyo Company, Limited Dihydroindolizinone derivative
JOP20210298A1 (ar) 2019-05-14 2023-01-30 Provention Bio Inc طرق وتركيبات للوقاية من مرض السكري من النوع الأول
CA3139294A1 (en) 2019-05-22 2020-11-26 The Cleveland Clinic Foundation Generating dorsal foregut, and anterior domain, endoderm cells
CN110585242A (zh) * 2019-10-15 2019-12-20 南通大学 多系分化持续应激细胞的应用、治疗糖尿病的药物及其制备方法
CN111411072B (zh) * 2020-03-09 2022-10-11 同济大学 SLC30A8基因表达下调的抗糖尿病胰岛β细胞及其应用
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물

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US6703017B1 (en) * 1994-04-28 2004-03-09 Ixion Biotechnology, Inc. Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
BR0213805A (pt) * 2001-11-09 2005-08-16 Artecel Sciences Inc Células estromais derivadas de tecido adiposo para diferenciação endócrina do pâncreas e usos das mesmas
EP1509087A4 (en) * 2002-05-24 2005-12-21 Waratah Pharmaceuticals Inc TREATMENT FOR DIABETES
WO2004023100A2 (en) * 2002-09-06 2004-03-18 Amcyte Inc. Cd56 positive human adult pancreatic endocrine progenitor cells
PL1641914T3 (pl) 2003-06-27 2017-01-31 DePuy Synthes Products, Inc. Komórki pochodzące z poporodowej tkanki łożyska oraz sposoby uzyskiwania i zastosowania tych komórek
CN1589904A (zh) * 2003-09-01 2005-03-09 北京大学 造血干细胞动员剂制备治疗糖尿病药物的用途
JP2006149380A (ja) * 2004-10-27 2006-06-15 Kobe Univ 遺伝子改変動物の新規用途
AU2006202209B2 (en) 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
WO2008054716A2 (en) * 2006-10-31 2008-05-08 National Stem Cell Holding Inc. Methods for identifying, isolating, and utilizing endocrine progenitor cells from adult human pancreata
CN101588795A (zh) * 2006-11-09 2009-11-25 奥雷西根治疗公司 包含中间快速溶解层的分层药物制剂
CN107574142B (zh) 2007-11-27 2021-07-06 生命扫描有限公司 人胚胎干细胞的分化
US20090280096A1 (en) * 2008-05-09 2009-11-12 Atsushi Kubo Pancreatic endocrine progenitor cells derived from pluripotent stem cells
NZ594044A (en) * 2009-02-13 2014-08-29 Boehringer Ingelheim Int Antidiabetic medications comprising a dpp-4 inhibitor (linagliptin) optionally in combination with other antidiabetics
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Publication number Publication date
US20180055890A1 (en) 2018-03-01
CA2979293C (en) 2022-01-04
WO2016141460A1 (en) 2016-09-15
EP3268016A1 (en) 2018-01-17
EP3268016B1 (en) 2021-04-28
US10772917B2 (en) 2020-09-15
CN107530379A (zh) 2018-01-02
AU2016228894B2 (en) 2021-03-04
AU2016228894A1 (en) 2017-11-02
EP3268016A4 (en) 2018-12-12
JP2018507889A (ja) 2018-03-22
US20210015872A1 (en) 2021-01-21
CA2979293A1 (en) 2016-09-15

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