JP6845858B2 - サンプルを分析し、光信号検出器の性能を監視するシステム及び方法 - Google Patents

サンプルを分析し、光信号検出器の性能を監視するシステム及び方法 Download PDF

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JP6845858B2
JP6845858B2 JP2018534555A JP2018534555A JP6845858B2 JP 6845858 B2 JP6845858 B2 JP 6845858B2 JP 2018534555 A JP2018534555 A JP 2018534555A JP 2018534555 A JP2018534555 A JP 2018534555A JP 6845858 B2 JP6845858 B2 JP 6845858B2
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fluorometer
carrier
receptacle
intensity
fluorescent surface
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JP2019504315A (ja
JP2019504315A5 (enExample
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デイビッド オパルスキー，
デイビッド オパルスキー，
スラジャン ラグワンシ，
スラジャン ラグワンシ，
ジェイムズ ブイ，
ジェイムズ ブイ，
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ジェン−プローブ・インコーポレーテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0332—Cuvette constructions with temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G01N21/276—Calibration, base line adjustment, drift correction with alternation of sample and standard in optical path
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0453—Multiple carousels working in parallel
    • G01N2035/0455—Coaxial carousels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0475—Details of actuating means for conveyors or pipettes electric, e.g. stepper motor, solenoid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0482—Transmission
    • G01N2035/0484—Belt or chain
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0407—Batch operation; multisample devices with multiple optical units, e.g. one per sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0415—Carrusel, sequential
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation
    • G01N2201/12723—Self check capacity; automatic, periodic step of checking
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Mathematical Physics (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Optics & Photonics (AREA)
JP2018534555A 2015-12-31 2016-12-22 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法 Active JP6845858B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2020150320A JP7320480B2 (ja) 2015-12-31 2020-09-08 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法
JP2022069401A JP2022093423A (ja) 2015-12-31 2022-04-20 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562274027P 2015-12-31 2015-12-31
US62/274,027 2015-12-31
PCT/US2016/068384 WO2017117011A1 (en) 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector

Related Child Applications (1)

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JP2020150320A Division JP7320480B2 (ja) 2015-12-31 2020-09-08 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法

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JP2019504315A JP2019504315A (ja) 2019-02-14
JP2019504315A5 JP2019504315A5 (enExample) 2019-12-12
JP6845858B2 true JP6845858B2 (ja) 2021-03-24

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JP2018534555A Active JP6845858B2 (ja) 2015-12-31 2016-12-22 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法
JP2020150320A Active JP7320480B2 (ja) 2015-12-31 2020-09-08 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法
JP2022069401A Withdrawn JP2022093423A (ja) 2015-12-31 2022-04-20 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法

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JP2020150320A Active JP7320480B2 (ja) 2015-12-31 2020-09-08 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法
JP2022069401A Withdrawn JP2022093423A (ja) 2015-12-31 2022-04-20 サンプルを分析し、光信号検出器の性能を監視するシステム及び方法

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US (4) US10190984B2 (enExample)
EP (2) EP3764079B1 (enExample)
JP (3) JP6845858B2 (enExample)
CN (1) CN108369180B (enExample)
AU (3) AU2016380168B2 (enExample)
CA (1) CA3008891C (enExample)
WO (1) WO2017117011A1 (enExample)

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CN116601482A (zh) * 2020-12-21 2023-08-15 恩德莱斯和豪瑟尔分析仪表两合公司 用于测量测量介质中发光分析物的光化学传感器和方法
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Publication number Publication date
WO2017117011A1 (en) 2017-07-06
JP2019504315A (ja) 2019-02-14
US20170191933A1 (en) 2017-07-06
CN108369180B (zh) 2022-12-16
CA3008891C (en) 2024-02-20
US11402330B2 (en) 2022-08-02
AU2022203734A1 (en) 2022-06-23
CA3008891A1 (en) 2017-07-06
JP2022093423A (ja) 2022-06-23
AU2016380168B2 (en) 2022-03-10
JP2020197543A (ja) 2020-12-10
EP3764079B1 (en) 2023-08-09
US20220364988A1 (en) 2022-11-17
CN108369180A (zh) 2018-08-03
US20190128810A1 (en) 2019-05-02
AU2024200422A1 (en) 2024-02-08
US10739263B2 (en) 2020-08-11
AU2022203734B2 (en) 2023-10-26
EP3397947A1 (en) 2018-11-07
EP3397947B1 (en) 2020-04-29
EP3764079A1 (en) 2021-01-13
AU2024200422B2 (en) 2024-05-09
AU2016380168A1 (en) 2018-08-09
JP7320480B2 (ja) 2023-08-03
US11726041B2 (en) 2023-08-15
US20200355610A1 (en) 2020-11-12
US10190984B2 (en) 2019-01-29

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