AU2016380168B2 - Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector - Google Patents

Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector Download PDF

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Publication number
AU2016380168B2
AU2016380168B2 AU2016380168A AU2016380168A AU2016380168B2 AU 2016380168 B2 AU2016380168 B2 AU 2016380168B2 AU 2016380168 A AU2016380168 A AU 2016380168A AU 2016380168 A AU2016380168 A AU 2016380168A AU 2016380168 B2 AU2016380168 B2 AU 2016380168B2
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AU
Australia
Prior art keywords
fluorometer
carrier
receptacle
intensity
sensor
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AU2016380168A
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AU2016380168A1 (en
Inventor
James BUI
David Opalsky
Srajan RAGHUWANSHI
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Gen Probe Inc
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Gen Probe Inc
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Publication of AU2016380168A1 publication Critical patent/AU2016380168A1/en
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Publication of AU2016380168B2 publication Critical patent/AU2016380168B2/en
Priority to AU2022203734A priority Critical patent/AU2022203734B2/en
Priority to AU2024200422A priority patent/AU2024200422B2/en
Active legal-status Critical Current
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0332Cuvette constructions with temperature control
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • G01N21/276Calibration, base line adjustment, drift correction with alternation of sample and standard in optical path
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00356Holding samples at elevated temperature (incubation)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0439Rotary sample carriers, i.e. carousels
    • G01N2035/0453Multiple carousels working in parallel
    • G01N2035/0455Coaxial carousels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0474Details of actuating means for conveyors or pipettes
    • G01N2035/0475Details of actuating means for conveyors or pipettes electric, e.g. stepper motor, solenoid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0474Details of actuating means for conveyors or pipettes
    • G01N2035/0482Transmission
    • G01N2035/0484Belt or chain
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/04Batch operation; multisample devices
    • G01N2201/0407Batch operation; multisample devices with multiple optical units, e.g. one per sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/04Batch operation; multisample devices
    • G01N2201/0415Carrusel, sequential
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/127Calibration; base line adjustment; drift compensation
    • G01N2201/12723Self check capacity; automatic, periodic step of checking
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Optics & Photonics (AREA)
AU2016380168A 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector Active AU2016380168B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2022203734A AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2024200422A AU2024200422B2 (en) 2015-12-31 2024-01-23 System for Measuring Optical Signal Detector Performance

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562274027P 2015-12-31 2015-12-31
US62/274,027 2015-12-31
PCT/US2016/068384 WO2017117011A1 (en) 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2022203734A Division AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector

Publications (2)

Publication Number Publication Date
AU2016380168A1 AU2016380168A1 (en) 2018-08-09
AU2016380168B2 true AU2016380168B2 (en) 2022-03-10

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Family Applications (3)

Application Number Title Priority Date Filing Date
AU2016380168A Active AU2016380168B2 (en) 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2022203734A Active AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2024200422A Active AU2024200422B2 (en) 2015-12-31 2024-01-23 System for Measuring Optical Signal Detector Performance

Family Applications After (2)

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AU2022203734A Active AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2024200422A Active AU2024200422B2 (en) 2015-12-31 2024-01-23 System for Measuring Optical Signal Detector Performance

Country Status (7)

Country Link
US (4) US10190984B2 (enExample)
EP (2) EP3764079B1 (enExample)
JP (3) JP6845858B2 (enExample)
CN (1) CN108369180B (enExample)
AU (3) AU2016380168B2 (enExample)
CA (1) CA3008891C (enExample)
WO (1) WO2017117011A1 (enExample)

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EP3764079B1 (en) 2015-12-31 2023-08-09 Gen-Probe Incorporated System and method for monitoring the performance of an optical signal detector
WO2020032905A2 (en) * 2018-08-09 2020-02-13 Hacettepe Universitesi An experiment assembly for evaluating equipment performance
CN109521197B (zh) * 2018-12-29 2022-03-11 重庆鼎润医疗器械有限责任公司 一种多通道荧光免疫分析仪
GB202001397D0 (en) * 2020-01-31 2020-03-18 Odx Innovations Ltd Apparatus, system and method for measuring properties of a sample
US20230107314A1 (en) * 2020-03-17 2023-04-06 Hitachi High-Tech Corporation Automatic analyzer
CN113567690B (zh) * 2020-04-28 2024-10-01 深圳迎凯生物科技有限公司 孵育组件、孵育装置和自动分析装置
CN116601482A (zh) * 2020-12-21 2023-08-15 恩德莱斯和豪瑟尔分析仪表两合公司 用于测量测量介质中发光分析物的光化学传感器和方法
US20250155460A1 (en) * 2022-02-14 2025-05-15 Hitachi High-Tech Corporation Parts Anomaly Detection System, Automatic Analyzer and Parts Anomaly Detection Method
US20240329212A1 (en) * 2023-03-27 2024-10-03 Rosemount Aerospace Inc. Optical imaging device degradation check

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Also Published As

Publication number Publication date
WO2017117011A1 (en) 2017-07-06
JP2019504315A (ja) 2019-02-14
US20170191933A1 (en) 2017-07-06
CN108369180B (zh) 2022-12-16
CA3008891C (en) 2024-02-20
US11402330B2 (en) 2022-08-02
AU2022203734A1 (en) 2022-06-23
CA3008891A1 (en) 2017-07-06
JP2022093423A (ja) 2022-06-23
JP2020197543A (ja) 2020-12-10
EP3764079B1 (en) 2023-08-09
JP6845858B2 (ja) 2021-03-24
US20220364988A1 (en) 2022-11-17
CN108369180A (zh) 2018-08-03
US20190128810A1 (en) 2019-05-02
AU2024200422A1 (en) 2024-02-08
US10739263B2 (en) 2020-08-11
AU2022203734B2 (en) 2023-10-26
EP3397947A1 (en) 2018-11-07
EP3397947B1 (en) 2020-04-29
EP3764079A1 (en) 2021-01-13
AU2024200422B2 (en) 2024-05-09
AU2016380168A1 (en) 2018-08-09
JP7320480B2 (ja) 2023-08-03
US11726041B2 (en) 2023-08-15
US20200355610A1 (en) 2020-11-12
US10190984B2 (en) 2019-01-29

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