JP6817966B2 - 高アンモニア血症に関連する疾患を治療するために操作された細菌 - Google Patents
高アンモニア血症に関連する疾患を治療するために操作された細菌 Download PDFInfo
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- JP6817966B2 JP6817966B2 JP2017564379A JP2017564379A JP6817966B2 JP 6817966 B2 JP6817966 B2 JP 6817966B2 JP 2017564379 A JP2017564379 A JP 2017564379A JP 2017564379 A JP2017564379 A JP 2017564379A JP 6817966 B2 JP6817966 B2 JP 6817966B2
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- bacterium
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- C12N15/09—Recombinant DNA-technology
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12R2001/00—Microorganisms ; Processes using microorganisms
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Applications Claiming Priority (31)
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| US14/960,333 US9487764B2 (en) | 2014-12-05 | 2015-12-04 | Bacteria engineered to treat diseases associated with hyperammonemia |
| US201662277654P | 2016-01-12 | 2016-01-12 | |
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| US62/293,749 | 2016-02-10 | ||
| PCT/US2016/020530 WO2016141108A1 (en) | 2015-03-02 | 2016-03-02 | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| USPCT/US2016/020530 | 2016-03-02 | ||
| PCT/US2016/034200 WO2016200614A2 (en) | 2015-06-10 | 2016-05-25 | Bacteria engineered to treat diseases associated with hyperammonemia |
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| WO2017136795A1 (en) | 2016-02-04 | 2017-08-10 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with tryptophan metabolism |
| BR112019024750A2 (pt) * | 2017-05-24 | 2020-06-09 | Thoeris Gmbh | uso de glutamina sintetase no tratamento da hiperamonemia |
| EP3720458A4 (en) * | 2017-12-05 | 2021-12-08 | BioPlx, Inc. | METHODS AND COMPOSITIONS FOR PREVENTING MICROBIAL INFECTION |
| CN110446259B (zh) * | 2018-05-04 | 2022-04-15 | 大唐移动通信设备有限公司 | 一种寻呼机会的位置确定方法及通信设备 |
| KR20220003030A (ko) | 2019-04-29 | 2022-01-07 | 신로직 오퍼레이팅 컴퍼니, 인코포레이티드 | 살아 있는 세포 계수 기술에 의한 유전적으로 조작된 미생물의 계수 |
| WO2020239882A1 (en) | 2019-05-30 | 2020-12-03 | Recordati Industria Chimica E Farmaceutica S.P.A. | Pharmaceutical formulation for carglumic acid |
| AU2020288624B2 (en) | 2019-06-04 | 2025-09-25 | Cocoon Biotech Inc. | Silk-based products, formulations, and methods of use |
| WO2021107500A1 (ko) | 2019-11-29 | 2021-06-03 | 주식회사 지니스 | 혈중 암모니아 수치 저하능을 갖는 균주 및 이를 포함하는 신경세포 보호용 조성물 |
| EP3839051A1 (en) * | 2019-12-19 | 2021-06-23 | Evonik Operations GmbH | Method for the fermentative production of guanidinoacetic acid |
| AU2021393455A1 (en) | 2020-12-02 | 2023-06-29 | Synlogic Operating Company, Inc. | Engineered microorganisms |
| EP4316685A4 (en) | 2021-03-31 | 2024-12-11 | Nippon Steel Corporation | NON-ORIENTED ELECTRICAL STEEL SHEET, METHOD FOR PUNCHING NON-ORIENTED ELECTRICAL STEEL SHEET, AND DIE FOR PUNCHING NON-ORIENTED ELECTRICAL STEEL SHEET |
| CN119592452B (zh) * | 2024-11-23 | 2025-12-02 | 清华大学 | 洋葱伯克霍尔德菌及其浸出废料中稀土元素的方法 |
| CN120000813A (zh) * | 2025-02-17 | 2025-05-16 | 温州医科大学 | 工程益生菌在防治阿尔茨海默病中的应用 |
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| IT1290679B1 (it) * | 1997-02-14 | 1998-12-10 | Alfa Wassermann Spa | Uso della rifaximina e delle composizioni farmaceutiche che la contengono nel trattamento della diarrea da criptosporidiosi. |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6203797B1 (en) | 1998-01-06 | 2001-03-20 | Stephen C. Perry | Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome |
| EP1135461A4 (en) | 1998-12-02 | 2003-03-26 | Univ Boston | GEN NETWORKS FOR CONTROLLING GENE EXPRESSION |
| EP1034787A1 (en) | 1999-03-11 | 2000-09-13 | Société des Produits Nestlé S.A. | Lactobacillus strains preventing diarrhea caused by pathogenic bacteria |
| US7731976B2 (en) | 2003-08-29 | 2010-06-08 | Cobb And Company, Llp | Treatment of irritable bowel syndrome using probiotic composition |
| WO2009123029A1 (ja) * | 2008-03-31 | 2009-10-08 | 株式会社 大塚製薬工場 | 血中アンモニア調整剤 |
| WO2015051323A1 (en) * | 2013-10-03 | 2015-04-09 | Trustees Of The University Of Pennsylvania | Compositions comprising a defined microbiome and methods of use thereof |
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| AU2016274311A1 (en) | 2018-01-18 |
| WO2016200614A2 (en) | 2016-12-15 |
| JP2018523978A (ja) | 2018-08-30 |
| WO2016200614A3 (en) | 2017-01-12 |
| JP2021061846A (ja) | 2021-04-22 |
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