JP6806685B2 - 急性放射線症候群を治療するための組成物及び方法 - Google Patents
急性放射線症候群を治療するための組成物及び方法 Download PDFInfo
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- JP6806685B2 JP6806685B2 JP2017534526A JP2017534526A JP6806685B2 JP 6806685 B2 JP6806685 B2 JP 6806685B2 JP 2017534526 A JP2017534526 A JP 2017534526A JP 2017534526 A JP2017534526 A JP 2017534526A JP 6806685 B2 JP6806685 B2 JP 6806685B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Toxicology (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051077P | 2014-09-16 | 2014-09-16 | |
| US62/051,077 | 2014-09-16 | ||
| US201562113298P | 2015-02-06 | 2015-02-06 | |
| US62/113,298 | 2015-02-06 | ||
| US201562211660P | 2015-08-28 | 2015-08-28 | |
| US62/211,660 | 2015-08-28 | ||
| PCT/US2015/050532 WO2016044493A1 (en) | 2014-09-16 | 2015-09-16 | Compositions and methods for treating acute radiation syndrome |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020201734A Division JP2021046432A (ja) | 2014-09-16 | 2020-12-04 | 急性放射線症候群を治療するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529396A JP2017529396A (ja) | 2017-10-05 |
| JP2017529396A5 JP2017529396A5 (enExample) | 2018-11-01 |
| JP6806685B2 true JP6806685B2 (ja) | 2021-01-06 |
Family
ID=55533820
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534526A Active JP6806685B2 (ja) | 2014-09-16 | 2015-09-16 | 急性放射線症候群を治療するための組成物及び方法 |
| JP2020201734A Pending JP2021046432A (ja) | 2014-09-16 | 2020-12-04 | 急性放射線症候群を治療するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020201734A Pending JP2021046432A (ja) | 2014-09-16 | 2020-12-04 | 急性放射線症候群を治療するための組成物及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20170319645A1 (enExample) |
| EP (1) | EP3193903A4 (enExample) |
| JP (2) | JP6806685B2 (enExample) |
| CN (1) | CN106999534A (enExample) |
| AU (3) | AU2015317771A1 (enExample) |
| CA (1) | CA2961375A1 (enExample) |
| IL (2) | IL295025A (enExample) |
| WO (1) | WO2016044493A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3341739A4 (en) | 2015-08-28 | 2019-07-10 | BioIncept LLC | MUTATED PEPTIDES AND METHOD FOR TREATING SUBJECTS THEREWITH |
| CA2996874A1 (en) | 2015-08-28 | 2017-03-09 | Bioincept, Llc | Compositions and methods for the treatment of neurodamage |
| WO2018156801A2 (en) * | 2017-02-22 | 2018-08-30 | Bioincept, Llc | Peptides and methods of treating dystrophy-related disorders using the same |
| AU2018304200A1 (en) * | 2017-07-17 | 2020-02-13 | Bioincept, Llc | Peptides and methods of transplantation and restorative organ function |
| WO2022047196A1 (en) | 2020-08-28 | 2022-03-03 | Nisibis, Llc-S | Pten inhibitors for treatment and prevention of bone marrow loss |
| WO2023056075A1 (en) * | 2021-10-01 | 2023-04-06 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for reduced toxicity in transplantation using janus kinase (jak) inhibitors |
| EP4248985A1 (en) * | 2022-03-25 | 2023-09-27 | Consejo Superior de Investigaciones Científicas (CSIC) | Peptides for the treatment of retinitis pigmentosa |
| WO2025117717A1 (en) * | 2023-11-27 | 2025-06-05 | The Brigham And Women’S Hospital, Inc. | Skin based test for detection of radiation exposure |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4629722A (en) * | 1984-07-12 | 1986-12-16 | Ribi Immunochem Research, Inc. | Method of inhibiting the onset of acute radiation syndrome |
| NZ547139A (en) * | 2003-10-22 | 2009-12-24 | Bioincept Llc | Use of preimplantation factor peptides to treat intolerence to embryo implantation |
| US7723290B2 (en) * | 2004-10-22 | 2010-05-25 | Bioincept, Llc | Compositions and methods for modulating the immune system |
| EP2680872B1 (en) * | 2011-03-02 | 2018-08-15 | BioIncept LLC | Use of pif peptides for treating infections, atherosclerosis and peritonitis |
| MX365403B (es) * | 2012-01-09 | 2019-05-31 | Serpin Pharma Llc | Peptidos y metodos para usarlos. |
| US20160263186A1 (en) * | 2013-10-22 | 2016-09-15 | Bioincept, Llc | Pif-transfected cells and methods of use |
-
2015
- 2015-09-16 AU AU2015317771A patent/AU2015317771A1/en not_active Abandoned
- 2015-09-16 WO PCT/US2015/050532 patent/WO2016044493A1/en not_active Ceased
- 2015-09-16 US US15/512,001 patent/US20170319645A1/en not_active Abandoned
- 2015-09-16 EP EP15842062.0A patent/EP3193903A4/en not_active Withdrawn
- 2015-09-16 IL IL295025A patent/IL295025A/en unknown
- 2015-09-16 JP JP2017534526A patent/JP6806685B2/ja active Active
- 2015-09-16 CA CA2961375A patent/CA2961375A1/en not_active Abandoned
- 2015-09-16 IL IL251108A patent/IL251108B/en unknown
- 2015-09-16 CN CN201580061796.4A patent/CN106999534A/zh active Pending
-
2019
- 2019-04-18 AU AU2019202741A patent/AU2019202741A1/en not_active Abandoned
-
2020
- 2020-12-04 JP JP2020201734A patent/JP2021046432A/ja active Pending
-
2021
- 2021-04-16 AU AU2021202310A patent/AU2021202310A1/en not_active Abandoned
- 2021-09-10 US US17/472,574 patent/US20220249595A1/en not_active Abandoned
-
2024
- 2024-05-31 US US18/731,133 patent/US12458681B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2961375A1 (en) | 2016-03-24 |
| AU2015317771A1 (en) | 2017-04-06 |
| WO2016044493A1 (en) | 2016-03-24 |
| JP2021046432A (ja) | 2021-03-25 |
| US20240350580A1 (en) | 2024-10-24 |
| IL251108A0 (en) | 2017-04-30 |
| JP2017529396A (ja) | 2017-10-05 |
| IL295025A (en) | 2022-09-01 |
| CN106999534A (zh) | 2017-08-01 |
| US20170319645A1 (en) | 2017-11-09 |
| IL251108B (en) | 2022-08-01 |
| AU2019202741A1 (en) | 2019-05-16 |
| EP3193903A4 (en) | 2018-03-14 |
| US12458681B2 (en) | 2025-11-04 |
| US20220249595A1 (en) | 2022-08-11 |
| EP3193903A1 (en) | 2017-07-26 |
| AU2021202310A1 (en) | 2021-05-20 |
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