JP6794258B2 - オリゴヌクレオチドについてのホスホロジアミデート骨格結合 - Google Patents

オリゴヌクレオチドについてのホスホロジアミデート骨格結合 Download PDF

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JP6794258B2
JP6794258B2 JP2016545246A JP2016545246A JP6794258B2 JP 6794258 B2 JP6794258 B2 JP 6794258B2 JP 2016545246 A JP2016545246 A JP 2016545246A JP 2016545246 A JP2016545246 A JP 2016545246A JP 6794258 B2 JP6794258 B2 JP 6794258B2
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hydrogen
compound
salt
alkyl
oligonucleotide
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JP2016533391A5 (enExample
JP2016533391A (ja
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クリスティーナ ポングラクズ，
クリスティーナ ポングラクズ，
マヘシュ ラマセシャン，
マヘシュ ラマセシャン，
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Geron Corp
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Geron Corp
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JP2016545246A 2013-09-30 2014-09-26 オリゴヌクレオチドについてのホスホロジアミデート骨格結合 Active JP6794258B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361884848P 2013-09-30 2013-09-30
US61/884,848 2013-09-30
PCT/US2014/057876 WO2015048558A1 (en) 2013-09-30 2014-09-26 Phosphorodiamidate backbone linkage for oligonucleotides

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JP2019017856A Division JP2019065054A (ja) 2013-09-30 2019-02-04 オリゴヌクレオチドについてのホスホロジアミデート骨格結合

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JP2016533391A JP2016533391A (ja) 2016-10-27
JP2016533391A5 JP2016533391A5 (enExample) 2017-11-24
JP6794258B2 true JP6794258B2 (ja) 2020-12-02

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JP2019017856A Pending JP2019065054A (ja) 2013-09-30 2019-02-04 オリゴヌクレオチドについてのホスホロジアミデート骨格結合

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US (2) US9708360B2 (enExample)
EP (2) EP3052512A4 (enExample)
JP (2) JP6794258B2 (enExample)
CA (1) CA2925500C (enExample)
WO (1) WO2015048558A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2925500C (en) * 2013-09-30 2023-03-14 Geron Corporation Phosphorodiamidate backbone linkage for oligonucleotides
CN109160931A (zh) * 2017-08-17 2019-01-08 王秀香 一种1/2水胞磷胆碱钠化合物
WO2020086311A1 (en) * 2018-10-23 2020-04-30 The Regents Of The University Of California Thiophosphorodichloridate reagents for chemoselective histidine bioconjugation

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US9708360B2 (en) 2017-07-18
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CA2925500A1 (en) 2015-04-02
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