JP6781807B2 - 組織酸素化の測定用の器具、システムおよびメソッド - Google Patents
組織酸素化の測定用の器具、システムおよびメソッド Download PDFInfo
- Publication number
- JP6781807B2 JP6781807B2 JP2019125937A JP2019125937A JP6781807B2 JP 6781807 B2 JP6781807 B2 JP 6781807B2 JP 2019125937 A JP2019125937 A JP 2019125937A JP 2019125937 A JP2019125937 A JP 2019125937A JP 6781807 B2 JP6781807 B2 JP 6781807B2
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- monitoring device
- probe
- oxygenation
- injectable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000000287 tissue oxygenation Effects 0.000 title claims description 80
- 238000000034 method Methods 0.000 title description 56
- 210000001519 tissue Anatomy 0.000 claims description 307
- 239000000523 sample Substances 0.000 claims description 141
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 124
- 229910052760 oxygen Inorganic materials 0.000 claims description 124
- 239000001301 oxygen Substances 0.000 claims description 124
- 238000006213 oxygenation reaction Methods 0.000 claims description 57
- 238000012806 monitoring device Methods 0.000 claims description 56
- 230000003287 optical effect Effects 0.000 claims description 55
- 230000004044 response Effects 0.000 claims description 36
- 238000005259 measurement Methods 0.000 claims description 27
- 230000001419 dependent effect Effects 0.000 claims description 24
- 230000010412 perfusion Effects 0.000 claims description 18
- 238000012544 monitoring process Methods 0.000 claims description 12
- 238000010521 absorption reaction Methods 0.000 claims description 11
- 210000001525 retina Anatomy 0.000 claims description 11
- 230000003993 interaction Effects 0.000 claims description 10
- 210000001328 optic nerve Anatomy 0.000 claims description 7
- 239000000758 substrate Substances 0.000 claims description 7
- 239000003302 ferromagnetic material Substances 0.000 claims description 6
- 230000005291 magnetic effect Effects 0.000 claims description 6
- 210000004556 brain Anatomy 0.000 claims description 5
- 230000001953 sensory effect Effects 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims description 2
- 230000005294 ferromagnetic effect Effects 0.000 claims description 2
- 210000003625 skull Anatomy 0.000 claims description 2
- 230000010363 phase shift Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 description 95
- 238000001356 surgical procedure Methods 0.000 description 38
- 238000002347 injection Methods 0.000 description 33
- 239000007924 injection Substances 0.000 description 33
- 230000003872 anastomosis Effects 0.000 description 31
- 238000010791 quenching Methods 0.000 description 31
- 230000000171 quenching effect Effects 0.000 description 31
- 238000003384 imaging method Methods 0.000 description 23
- 210000000936 intestine Anatomy 0.000 description 16
- 206010028980 Neoplasm Diseases 0.000 description 15
- 230000006870 function Effects 0.000 description 15
- 238000002271 resection Methods 0.000 description 15
- 230000017531 blood circulation Effects 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 13
- 239000008280 blood Substances 0.000 description 13
- 210000004027 cell Anatomy 0.000 description 13
- 239000003068 molecular probe Substances 0.000 description 13
- 230000006835 compression Effects 0.000 description 12
- 238000007906 compression Methods 0.000 description 12
- 230000000968 intestinal effect Effects 0.000 description 11
- 102000008186 Collagen Human genes 0.000 description 10
- 108010035532 Collagen Proteins 0.000 description 10
- 230000009102 absorption Effects 0.000 description 10
- 229920001436 collagen Polymers 0.000 description 10
- 239000010410 layer Substances 0.000 description 10
- 230000033001 locomotion Effects 0.000 description 10
- 210000001508 eye Anatomy 0.000 description 9
- 238000013459 approach Methods 0.000 description 8
- 230000015572 biosynthetic process Effects 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 102000001554 Hemoglobins Human genes 0.000 description 7
- 108010054147 Hemoglobins Proteins 0.000 description 7
- 230000008901 benefit Effects 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 7
- 238000000520 microinjection Methods 0.000 description 7
- 210000000664 rectum Anatomy 0.000 description 7
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 6
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 6
- 206010052428 Wound Diseases 0.000 description 6
- 208000027418 Wounds and injury Diseases 0.000 description 6
- 238000003491 array Methods 0.000 description 6
- 238000004891 communication Methods 0.000 description 6
- 230000007423 decrease Effects 0.000 description 6
- 238000001802 infusion Methods 0.000 description 6
- 238000007917 intracranial administration Methods 0.000 description 6
- 239000013307 optical fiber Substances 0.000 description 6
- 210000000056 organ Anatomy 0.000 description 6
- 210000005070 sphincter Anatomy 0.000 description 6
- 230000035899 viability Effects 0.000 description 6
- 206010009944 Colon cancer Diseases 0.000 description 5
- 208000015634 Rectal Neoplasms Diseases 0.000 description 5
- 238000001444 catalytic combustion detection Methods 0.000 description 5
- 230000005284 excitation Effects 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 230000002496 gastric effect Effects 0.000 description 5
- 230000036541 health Effects 0.000 description 5
- 230000001900 immune effect Effects 0.000 description 5
- 230000001965 increasing effect Effects 0.000 description 5
- 238000013507 mapping Methods 0.000 description 5
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 5
- 206010038038 rectal cancer Diseases 0.000 description 5
- 201000001275 rectum cancer Diseases 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 210000002105 tongue Anatomy 0.000 description 5
- 230000002792 vascular Effects 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000012190 activator Substances 0.000 description 4
- 230000008033 biological extinction Effects 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 4
- 210000001072 colon Anatomy 0.000 description 4
- 230000001276 controlling effect Effects 0.000 description 4
- 239000000412 dendrimer Substances 0.000 description 4
- 229920000736 dendritic polymer Polymers 0.000 description 4
- 239000006260 foam Substances 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 210000003491 skin Anatomy 0.000 description 4
- 238000001228 spectrum Methods 0.000 description 4
- 239000000090 biomarker Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 210000004087 cornea Anatomy 0.000 description 3
- 230000000875 corresponding effect Effects 0.000 description 3
- 230000034994 death Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 239000010419 fine particle Substances 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- 208000003243 intestinal obstruction Diseases 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000002106 pulse oximetry Methods 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 230000003874 surgical anastomosis Effects 0.000 description 3
- 210000004876 tela submucosa Anatomy 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010050456 Anastomotic leak Diseases 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 241001631457 Cannula Species 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- 208000035346 Margins of Excision Diseases 0.000 description 2
- 230000003187 abdominal effect Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 210000005013 brain tissue Anatomy 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 230000003788 cerebral perfusion Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 229910001882 dioxygen Inorganic materials 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000000763 evoking effect Effects 0.000 description 2
- 210000002950 fibroblast Anatomy 0.000 description 2
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 2
- 210000000232 gallbladder Anatomy 0.000 description 2
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004020 luminiscence type Methods 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000011859 microparticle Substances 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 210000000440 neutrophil Anatomy 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 238000002496 oximetry Methods 0.000 description 2
- 229910052763 palladium Inorganic materials 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 230000006320 pegylation Effects 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 229910052697 platinum Inorganic materials 0.000 description 2
- 150000004032 porphyrins Chemical group 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000700 radioactive tracer Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 230000033764 rhythmic process Effects 0.000 description 2
- 210000003786 sclera Anatomy 0.000 description 2
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000011477 surgical intervention Methods 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- GODZNYBQGNSJJN-UHFFFAOYSA-N 1-aminoethane-1,2-diol Chemical compound NC(O)CO GODZNYBQGNSJJN-UHFFFAOYSA-N 0.000 description 1
- 206010051268 Anastomotic stenosis Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- SAGJYKXXZKAFED-UHFFFAOYSA-N C(=O)(O)C=1C=C(C=C(C1)C(=O)O)C1=C2C3=C(C(N2)=CC=2C4=C(C(=CC5=C6C(=C(C=C7C8=C(C1=N7)C=CC=C8)N5)C=CC=C6)N2)C=CC=C4)C=CC=C3 Chemical compound C(=O)(O)C=1C=C(C=C(C1)C(=O)O)C1=C2C3=C(C(N2)=CC=2C4=C(C(=CC5=C6C(=C(C=C7C8=C(C1=N7)C=CC=C8)N5)C=CC=C6)N2)C=CC=C4)C=CC=C3 SAGJYKXXZKAFED-UHFFFAOYSA-N 0.000 description 1
- 241000282465 Canis Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010014418 Electrolyte imbalance Diseases 0.000 description 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 206010021137 Hypovolaemia Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010034972 Photosensitivity reaction Diseases 0.000 description 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 206010066902 Surgical failure Diseases 0.000 description 1
- 206010053648 Vascular occlusion Diseases 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000000862 absorption spectrum Methods 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 238000011226 adjuvant chemotherapy Methods 0.000 description 1
- 238000009098 adjuvant therapy Methods 0.000 description 1
- 230000001919 adrenal effect Effects 0.000 description 1
- 210000004100 adrenal gland Anatomy 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 210000002255 anal canal Anatomy 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000008321 arterial blood flow Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 201000005008 bacterial sepsis Diseases 0.000 description 1
- 231100000693 bioaccumulation Toxicity 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 229920001222 biopolymer Polymers 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 231100000504 carcinogenesis Toxicity 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000004098 cellular respiration Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 230000000112 colonic effect Effects 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 238000011833 dog model Methods 0.000 description 1
- 238000012279 drainage procedure Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003027 ear inner Anatomy 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 238000002565 electrocardiography Methods 0.000 description 1
- 238000002674 endoscopic surgery Methods 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 210000000873 fovea centralis Anatomy 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 238000011902 gastrointestinal surgery Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000001744 histochemical effect Effects 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000033444 hydroxylation Effects 0.000 description 1
- 238000005805 hydroxylation reaction Methods 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 210000003405 ileum Anatomy 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 229960004657 indocyanine green Drugs 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000004969 inflammatory cell Anatomy 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000003886 intestinal anastomosis Effects 0.000 description 1
- 238000007913 intrathecal administration Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 238000002357 laparoscopic surgery Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 210000003563 lymphoid tissue Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000000816 matrix-assisted laser desorption--ionisation Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000005170 neoplastic cell Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000008035 nerve activity Effects 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000002355 open surgical procedure Methods 0.000 description 1
- 210000004789 organ system Anatomy 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 238000002428 photodynamic therapy Methods 0.000 description 1
- 230000036211 photosensitivity Effects 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007467 rectal resection Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000002207 retinal effect Effects 0.000 description 1
- 230000004256 retinal image Effects 0.000 description 1
- 229910052707 ruthenium Inorganic materials 0.000 description 1
- 210000004706 scrotum Anatomy 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000012306 spectroscopic technique Methods 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- -1 structures Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 208000021331 vascular occlusion disease Diseases 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B17/07207—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously the staples being applied sequentially
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/115—Staplers for performing anastomosis in a single operation
- A61B17/1155—Circular staplers comprising a plurality of staples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00057—Light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00084—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B2017/07214—Stapler heads
- A61B2017/07257—Stapler heads characterised by its anvil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
- A61B2090/065—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension for measuring contact or contact pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
- A61B2505/05—Surgical care
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0238—Optical sensor arrangements for performing transmission measurements on body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6868—Brain
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Surgical Instruments (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Endoscopes (AREA)
Description
本出願はその特許の全体を本明細書に参考として組み込まれる2013年3月19日に出願された米国仮特許出願第61/803,451号に対する優先権を主張する。
本発明はアメリカ国立衛生研究所グラント番号CA153571の下政府サポートに基づいて行われた。政府は本発明に対して一部の権利を有する。
本願明細書は、例えば、以下の項目も提供する。
(項目1)
組織酸素化の測定のために再発光プローブを検知するように構成された外科用装置は、
再発光プローブの吸収帯内で再発光プローブを励起するように構成された最低1つの光エミッタ、
プローブから再発光される光を受信するように構成された最低1つの光ディテクタ、および
受信した光に基づいて組織酸素化の測定ために構成された信号プロセッサで構成される。
(項目2)
項目1に記載の外科用装置は、更に再発光プローブを含む媒体を標的組織に提供するように構成されたアプリケータで構成される。
(項目3)
項目1に記載の外科用装置では、信号プロセッサが再発光プローブの寿命に基づいて組織酸素化の測定のために構成される。
(項目4)
項目1に記載の外科用装置は、外科用ステイプラーのアンビルである。
(項目5)
項目2に記載の外科用装置では、アプリケータは媒体を標的組織に注入するように構成された最低1つのインジェクタである。
(項目6)
項目1に記載の外科用装置は、更に組織を測定するように構成されたインテロゲータで構成される。
(項目7)
項目1に記載の外科用装置は、表面とインターフェースする組織を有するフレキシブルなサブストレートである。
(項目8)
項目1に記載の外科用装置では、信号プロセッサが組織酸素化の測定に基づいて運用の成否を決定する。
(項目9)
項目1に記載の外科用装置は、更に組織の温度を検出するように構成された温度センサーで構成される。
(項目10)
項目1に記載の外科用装置は、更に圧縮圧および組織間緊張組織の最低1つの相互作用力を監視するように構成された最低1つのセンサーで構成される。
(項目11)
項目1に記載の外科用装置では、プローブは多重吸収波長を有するリン光性プローブである。
(項目12)
項目1に記載の外科用装置は、基地局に通信可能に接続される。
(項目13)
組織酸素化の測定のために再発光プローブを検知するように構成された外科用ステイプラーのアンビル構成は、
再発光プローブを励起するように構成された最低1つの光エミッタ、
プローブから再発光される光を受信するように構成された最低1つの光ディテクタ、および
受信した光に基づいて組織酸素化の測定ために構成された信号プロセッサで構成される。
(項目14)
項目13に記載の外科用ステイプラーのアンビルは、基地局に通信可能に接続される。
(項目15)
項目13に記載の外科用ステイプラーのアンビルでは、信号プロセッサが組織酸素化の測定に基づいて運用の成否を決定する。
(項目16)
項目13に記載の外科用ステイプラーのアンビルは、更に組織の温度を検出するように構成された温度センサーで構成される。
(項目17)
項目13に記載の外科用ステイプラーのアンビルは、更に圧縮圧および組織間緊張組織の最低1つの相互作用力を監視するように構成された最低1つのセンサーで構成される。
(項目18)
組織酸素化の測定のために再発光プローブを検知するように構成された監視装置は、
表面とインターフェースする組織を有するフレキシブルなサブストレート、表面とインターフェースする組織((1)再発光プローブを励起するように構成された最低1つの光エミッタ、および(2)プローブから再発光される光を受信するように構成された最低1つの光ディテクタ、および
受信した光に基づいて組織酸素化の測定ために構成された信号プロセッサを含む)で構成される。
(項目19)
項目18に記載の監視装置は媒体を標的組織に注入するように構成された最低1つのインジェクタ、再発光プローブを含む媒体で構成される。
(項目20)
項目18に記載の監視装置は、基地局に通信可能に接続される。
(項目21)
項目18に記載の監視装置では、信号プロセッサが組織酸素化の測定に基づいて運用の成否を決定する。
(項目22)
項目18に記載の監視装置は、更に組織の温度を検出するように構成された温度センサーで構成される。
(項目23)
項目18に記載の監視装置では、フレキシブルなサブストレートが(1)皮膚に貼り付け(2)内部組織に貼り付けの1つ以上で構成される。
(項目24)
項目18に記載の監視装置は、少なくとも部分的に生体吸収性がある。
(項目25)
再発光プローブを含む組織酸素化をマッピングするように構成された監視装置は、
再発光プローブを励起するように構成された最低1つの光エミッタ、
プローブから再発光される光を受信するように構成された最低1つの光ディテクタ、および
酸素マップを生成するために多点で組織酸素化の測定ために構成された信号プロセッサで構成される。
(項目26)
項目25に記載の監視装置は媒体を標的組織に注入するように構成された最低1つのインジェクタ、再発光プローブを含む媒体で構成される。
(項目27)
項目25に記載の監視装置は、更に組織の温度を検出するように構成された温度センサーで構成される。
(項目28)
項目25に記載の監視装置では、光ディテクタはCCDアレイの最低1つ、CMOS画像センサーおよび1台のカメラで構成される。
(項目29)
項目25に記載の監視装置は、内視鏡装置である。
(項目30)
項目25に記載の監視装置は、摂取可能である。
各外科的処置は失敗する可能性がある。胃腸の手術における一般的な処置は腸切除である − 腸の患部を切除し、残りのセグメントの両端を機械的に接合し、腸の連続性を再確立する。腸の自由端の機械的接続はいわゆる外科的吻合を形成する。外科的吻合は縫合材を使用する従来の技術または外科用ステイプラーまたはその他の外科用固定装置の利用を含む現代の技術のいずれかによって形成される。外科用ステイプラーはカートリッジまたはハウジングから、反対側の固定クリンプを最終的に形成するアンビルに対して腸の2つの自由端を通してステイプラーのパターンを発射して腸を機械的に接合する。多くの外科用ステイプラーの実施態様がある。線形ステイプラーパターンや環状パターンである。いくつかのステイプラーは組織を切断する機能を持つ。多くのステイプラーはステイプラーのベースと形成されたクリンプの間のギャップを変えることができる。
BOC = ヘモグロビンに結合した酸素 + 溶解酸素
BOC = 1.34 * Hb * SO2 + 0.003 * PO2
図4bは、修正済み外科用ステイプラーのアンビル420の作業表面に面する切り抜き422に組み入れられた検知素子を使用した現発明の1つの代表的な構成である。1つの実施態様では、アンビル420は、制御回路430へのフレキシブルケーブル経由でセンサー素子インターフェース回路426に連結する。制御回路430はセンサー素子の制御と解釈用のプロセッサを含むことができる。制御回路は無線トランシーバ432経由で通信できる。装置はバッテリー436で電源を得る。すべてのコンポーネントがシェル、キャップまたはカバー438内に含まれる。
図4cはさらに光学446および機械的検知素子がステイプルフォーム442間のアンビルの面441内の空洞に統合されている1つの実施態様を詳述している。444はアンビルの表面442上の圧縮圧力を測定する圧力変換器のような機械的センサーを表す。445は統合された温度センサーを表す。446と447は光学センサー素子を表すが、446は1つ以上の光エミッタであり、447は1つの光ディテクタである。1つの実施態様では、光学センサー素子は深さ分解検知を有効にするように複数のピーク波長での多重光エミッタを含む。センサー素子444−447は表面441中でともに結合されたまたは分布されたものを含むさまざまな構成における空洞内に見つかる。カバーリップ448はセンサー素子のエッジを取り囲む。1つの実施態様では、検知コンポーネントは、外科用ステイプラーのアンビル、またはその代わりにステイプラーボディまたは他のコンポーネントに連結するシェルに取り込まれる。別の実施態様では、検知コンポーネントは、外科用ステイプラーのアンビルに直接取り込まれ、従来の非検知アンビルに置き換わる。いずれの場合も、検知シェルまたは交換アンビルは、外科用ステイプラーへのアクセサリーまたは付属物として役立ち、オプションとしてステイプラーに連結できる。検知アンビルはスタンドアロン装置として使用することもできるし、またはインテロゲータのような追加装置と結合して使用できる。
図11に示す技術は、他の外科用装置に直接適用される。1つの実施態様では、装置1101は外科用ステイプラーのアンビルである。アンビルはステイプルフォームを組み込んだ顔面1119を持つ。検知素子1127および1129は、表面1119の組織接触面にあるように構成される。ニードル1137はアンビル表面1119、対向面、または内部の空洞に統合してもよい。1つの構成では、リザーバ1143はアンビルの空洞内部に収容され、プランジャー1149はアンビルが対向面に対して組織を圧縮するように作動される。このようにしてステイプラーが閉じると、媒体1143を組織に注入し、アンビルはステイプラー本体の対向面に対して組織を圧縮する。1つの構成では、媒体1143は、アンビルと対向面との間に配置された別の装置のリザーバに含まれる。この構成では、リザーバは圧縮され、アンビルが組織を圧縮すると組織に媒体を排出する。本発明は、注入装置が検知装置内に含まれた上述の実施態様の構成、およびインジェクタが検知装置の外部にあり、独立して操作されていてもよい構成を含む
図3に示す酸素イメージングシステムの例示的な実施態様(すなわち、酸素のマッピングシステム)は構成例であり、このアプローチは、他の器官系に対する他の構成で利用できる。更に好適な実施態様では、このアプローチは胃腸組織の酸素化を評価するために利用される。これはCRC手術の前、最中、後の酸素化を測定するために、前述のアプローチで利用できる。
Claims (21)
- 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記監視装置は、標的組織(954)に媒体(165,950)を提供するように構成されたアプリケータ(157,956)をさらに備え、前記媒体は、前記注入可能なプローブを含む、監視装置。 - 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記アプリケータ(474)は、媒体(165)を標的組織(151)中に注入するように構成されている少なくとも1つのインジェクタ(167,478,511,809,1149)である、監視装置。 - 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記監視装置は、前記組織(203,1007,1315)を調査するように構成されているインテロゲータ装置(201,301,1001,1101,1331)をさらに備える、監視装置。 - 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記信号プロセッサ(189,430,470)は、前記組織酸素化の解明に基づいて動作成功の決定を行う、監視装置。 - 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記監視装置は、前記組織の圧縮圧力および組織張力のうちの少なくとも1つの相互作用力を監視するように構成された少なくとも1つのセンサー(113,444,464,1117)をさらに備える、監視装置。 - 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記監視装置は、組織インターフェースする表面を有するフレキシブルなサブストレート(605,701)をさらに備え、前記組織インターフェースする表面は、前記少なくとも1つの光学エミッタと、前記少なくとも1つの光学ディテクタ(705)とを含む、監視装置。 - 前記信号プロセッサは、複数のポイント(110,112,405,513,705,1127,1129,1331,1351)における前記再放射された光の前記分析された周波数応答に基づいて前記組織酸素化を解明して、酸素マップを生成するように構成されている、請求項1〜6のうちのいずれかに記載の監視装置。
- 前記監視装置は、内視鏡装置(501,1331)である、請求項1〜7のうちのいずれかに記載の監視装置。
- 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記監視装置は、摂取可能である、監視装置。 - 前記監視装置は、外科用装置(101,155,201,301,401,450,501,605,1001,1101,1201,1331)である、請求項1〜8のうちのいずれかに記載の監視装置。
- 組織の組織酸素化を解明するために、光を再放射する注入可能なプローブ(118,153)を検知するように構成された監視装置(101,155,201,301,401,450,501,605,701,1001,1101,1201,1331,1351)であって、前記監視装置は、
前記注入可能なプローブを励起させるように構成されている少なくとも1つの光学エミッタ(173,1127)と、
前記注入可能なプローブから再放射された光を受信するように構成された少なくとも1つの光学ディテクタ(185,1129)と、
前記受信された光(181)の周波数応答を分析することによって前記組織の少なくとも1つのポイントの前記組織酸素化の解を得るように構成されている信号プロセッサ(189,430,470)と、
前記組織の温度を検出するように構成されているセンサー(445)と
を備え、
前記信号プロセッサ(189,470)は、前記組織酸素化を校正するために前記組織の前記検出された温度を利用するように構成されており、
前記監視装置は、外科用ステイプラーアンビル(401,450)である、監視装置。 - 前記少なくとも1つの光学エミッタ(173)は、前記注入可能なプローブの吸収帯内において前記注入可能なプローブを励起させるように構成されている、請求項1〜11のうちのいずれかに記載の監視装置。
- 前記信号プロセッサ(189,470)は、前記受信された光の酸素依存性光学応答に基づいて前記組織酸素化を解明するように構成されている、請求項1〜12のうちのいずれかに記載の監視装置。
- 前記監視装置は、解明された組織データを外部に通信するように構成され、前記監視装置は、
ディスプレイ(127)および感覚代行のうちの少なくとも1つと、
前記ディスプレイ(127)および感覚代行のうちの前記少なくとも1つと通信するように構成された外部インターフェース(125)と
をさらに備え、
前記信号プロセッサ(189,470)は、前記ディスプレイおよび感覚代行のうちの前記少なくとも1つに、解明され校正された酸素測定を通信するようにさらに構成されている、請求項1〜13のうちのいずれかに記載の監視装置。 - 前記信号プロセッサ(189,430,470,705)は、再放射された光の位相シフトに基づいて前記組織酸素化を解明するように構成されている、請求項1〜14のうちのいずれかに記載の監視装置。
- 前記媒体は、強磁性材料又は生体吸収性実体である、請求項1又は2に記載の監視装置。
- 前記注入可能なプローブは、強磁性材料と連結され、前記装置は、さらに、磁力で前記注入可能なプローブの伝達を制御するように構成された磁気コンポーネントを含む、請求項1〜6、9、11のうちのいずれかに記載の監視装置。
- 前記媒体は、強磁性であり、前記装置は、さらに、ジョーを備えた装置を含み、磁石は、前記媒体又は前記媒体に前記注入可能なプローブを制御可能に操作するために、前記ジョーに沿って装置の先端に配置される、請求項1又は2に記載の監視装置。
- さらに、媒体又は媒体の粒子を操作できるように制御可能な磁気コンポーネントを備える、請求項1又は2に記載の監視装置。
- 前記監視装置は、網膜又は視神経における酸素化又は灌流を評価するために構成されている、請求項1〜6、9、11のうちのいずれかに記載の監視装置。
- 前記監視装置は、網膜を超えて脳を含めた頭蓋骨内の一点を撮影するように構成されている、請求項1〜6、9、11のうちのいずれかに記載の監視装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361803451P | 2013-03-19 | 2013-03-19 | |
US61/803,451 | 2013-03-19 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016505500A Division JP6554089B2 (ja) | 2013-03-19 | 2014-03-19 | 組織酸素化の測定用の器具、システムおよびメソッド |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020174790A Division JP7164577B2 (ja) | 2013-03-19 | 2020-10-16 | 組織酸素化の測定用の器具、システムおよびメソッド |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2019184617A JP2019184617A (ja) | 2019-10-24 |
JP2019184617A5 JP2019184617A5 (ja) | 2019-12-26 |
JP6781807B2 true JP6781807B2 (ja) | 2020-11-04 |
Family
ID=51569632
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016505500A Active JP6554089B2 (ja) | 2013-03-19 | 2014-03-19 | 組織酸素化の測定用の器具、システムおよびメソッド |
JP2019125937A Active JP6781807B2 (ja) | 2013-03-19 | 2019-07-05 | 組織酸素化の測定用の器具、システムおよびメソッド |
JP2020174790A Active JP7164577B2 (ja) | 2013-03-19 | 2020-10-16 | 組織酸素化の測定用の器具、システムおよびメソッド |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016505500A Active JP6554089B2 (ja) | 2013-03-19 | 2014-03-19 | 組織酸素化の測定用の器具、システムおよびメソッド |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020174790A Active JP7164577B2 (ja) | 2013-03-19 | 2020-10-16 | 組織酸素化の測定用の器具、システムおよびメソッド |
Country Status (4)
Country | Link |
---|---|
US (4) | US9420967B2 (ja) |
EP (2) | EP4079242A1 (ja) |
JP (3) | JP6554089B2 (ja) |
WO (1) | WO2014153428A1 (ja) |
Families Citing this family (568)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070084897A1 (en) | 2003-05-20 | 2007-04-19 | Shelton Frederick E Iv | Articulating surgical stapling instrument incorporating a two-piece e-beam firing mechanism |
US9060770B2 (en) | 2003-05-20 | 2015-06-23 | Ethicon Endo-Surgery, Inc. | Robotically-driven surgical instrument with E-beam driver |
US8215531B2 (en) | 2004-07-28 | 2012-07-10 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument having a medical substance dispenser |
US11896225B2 (en) | 2004-07-28 | 2024-02-13 | Cilag Gmbh International | Staple cartridge comprising a pan |
US9237891B2 (en) | 2005-08-31 | 2016-01-19 | Ethicon Endo-Surgery, Inc. | Robotically-controlled surgical stapling devices that produce formed staples having different lengths |
US10159482B2 (en) | 2005-08-31 | 2018-12-25 | Ethicon Llc | Fastener cartridge assembly comprising a fixed anvil and different staple heights |
US11246590B2 (en) | 2005-08-31 | 2022-02-15 | Cilag Gmbh International | Staple cartridge including staple drivers having different unfired heights |
US11484312B2 (en) | 2005-08-31 | 2022-11-01 | Cilag Gmbh International | Staple cartridge comprising a staple driver arrangement |
US7934630B2 (en) | 2005-08-31 | 2011-05-03 | Ethicon Endo-Surgery, Inc. | Staple cartridges for forming staples having differing formed staple heights |
US7669746B2 (en) | 2005-08-31 | 2010-03-02 | Ethicon Endo-Surgery, Inc. | Staple cartridges for forming staples having differing formed staple heights |
US20070106317A1 (en) | 2005-11-09 | 2007-05-10 | Shelton Frederick E Iv | Hydraulically and electrically actuated articulation joints for surgical instruments |
US11278279B2 (en) | 2006-01-31 | 2022-03-22 | Cilag Gmbh International | Surgical instrument assembly |
US20110024477A1 (en) | 2009-02-06 | 2011-02-03 | Hall Steven G | Driven Surgical Stapler Improvements |
US11224427B2 (en) | 2006-01-31 | 2022-01-18 | Cilag Gmbh International | Surgical stapling system including a console and retraction assembly |
US8186555B2 (en) | 2006-01-31 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Motor-driven surgical cutting and fastening instrument with mechanical closure system |
US7753904B2 (en) | 2006-01-31 | 2010-07-13 | Ethicon Endo-Surgery, Inc. | Endoscopic surgical instrument with a handle that can articulate with respect to the shaft |
US11793518B2 (en) | 2006-01-31 | 2023-10-24 | Cilag Gmbh International | Powered surgical instruments with firing system lockout arrangements |
US8820603B2 (en) | 2006-01-31 | 2014-09-02 | Ethicon Endo-Surgery, Inc. | Accessing data stored in a memory of a surgical instrument |
US20110295295A1 (en) | 2006-01-31 | 2011-12-01 | Ethicon Endo-Surgery, Inc. | Robotically-controlled surgical instrument having recording capabilities |
US8708213B2 (en) | 2006-01-31 | 2014-04-29 | Ethicon Endo-Surgery, Inc. | Surgical instrument having a feedback system |
US7845537B2 (en) | 2006-01-31 | 2010-12-07 | Ethicon Endo-Surgery, Inc. | Surgical instrument having recording capabilities |
US20120292367A1 (en) | 2006-01-31 | 2012-11-22 | Ethicon Endo-Surgery, Inc. | Robotically-controlled end effector |
US8992422B2 (en) | 2006-03-23 | 2015-03-31 | Ethicon Endo-Surgery, Inc. | Robotically-controlled endoscopic accessory channel |
US8322455B2 (en) | 2006-06-27 | 2012-12-04 | Ethicon Endo-Surgery, Inc. | Manually driven surgical cutting and fastening instrument |
US7665647B2 (en) | 2006-09-29 | 2010-02-23 | Ethicon Endo-Surgery, Inc. | Surgical cutting and stapling device with closure apparatus for limiting maximum tissue compression force |
US10568652B2 (en) | 2006-09-29 | 2020-02-25 | Ethicon Llc | Surgical staples having attached drivers of different heights and stapling instruments for deploying the same |
US8684253B2 (en) | 2007-01-10 | 2014-04-01 | Ethicon Endo-Surgery, Inc. | Surgical instrument with wireless communication between a control unit of a robotic system and remote sensor |
US11291441B2 (en) | 2007-01-10 | 2022-04-05 | Cilag Gmbh International | Surgical instrument with wireless communication between control unit and remote sensor |
US8652120B2 (en) | 2007-01-10 | 2014-02-18 | Ethicon Endo-Surgery, Inc. | Surgical instrument with wireless communication between control unit and sensor transponders |
US20080169333A1 (en) | 2007-01-11 | 2008-07-17 | Shelton Frederick E | Surgical stapler end effector with tapered distal end |
US11039836B2 (en) | 2007-01-11 | 2021-06-22 | Cilag Gmbh International | Staple cartridge for use with a surgical stapling instrument |
US8727197B2 (en) | 2007-03-15 | 2014-05-20 | Ethicon Endo-Surgery, Inc. | Staple cartridge cavity configuration with cooperative surgical staple |
US8893946B2 (en) | 2007-03-28 | 2014-11-25 | Ethicon Endo-Surgery, Inc. | Laparoscopic tissue thickness and clamp load measuring devices |
US8931682B2 (en) | 2007-06-04 | 2015-01-13 | Ethicon Endo-Surgery, Inc. | Robotically-controlled shaft based rotary drive systems for surgical instruments |
US11564682B2 (en) | 2007-06-04 | 2023-01-31 | Cilag Gmbh International | Surgical stapler device |
US7753245B2 (en) | 2007-06-22 | 2010-07-13 | Ethicon Endo-Surgery, Inc. | Surgical stapling instruments |
US11849941B2 (en) | 2007-06-29 | 2023-12-26 | Cilag Gmbh International | Staple cartridge having staple cavities extending at a transverse angle relative to a longitudinal cartridge axis |
US9179912B2 (en) | 2008-02-14 | 2015-11-10 | Ethicon Endo-Surgery, Inc. | Robotically-controlled motorized surgical cutting and fastening instrument |
US7866527B2 (en) | 2008-02-14 | 2011-01-11 | Ethicon Endo-Surgery, Inc. | Surgical stapling apparatus with interlockable firing system |
US7819298B2 (en) | 2008-02-14 | 2010-10-26 | Ethicon Endo-Surgery, Inc. | Surgical stapling apparatus with control features operable with one hand |
US8573465B2 (en) | 2008-02-14 | 2013-11-05 | Ethicon Endo-Surgery, Inc. | Robotically-controlled surgical end effector system with rotary actuated closure systems |
US8758391B2 (en) | 2008-02-14 | 2014-06-24 | Ethicon Endo-Surgery, Inc. | Interchangeable tools for surgical instruments |
JP5410110B2 (ja) | 2008-02-14 | 2014-02-05 | エシコン・エンド−サージェリィ・インコーポレイテッド | Rf電極を有する外科用切断・固定器具 |
US8636736B2 (en) | 2008-02-14 | 2014-01-28 | Ethicon Endo-Surgery, Inc. | Motorized surgical cutting and fastening instrument |
US11272927B2 (en) | 2008-02-15 | 2022-03-15 | Cilag Gmbh International | Layer arrangements for surgical staple cartridges |
US10390823B2 (en) | 2008-02-15 | 2019-08-27 | Ethicon Llc | End effector comprising an adjunct |
US11648005B2 (en) | 2008-09-23 | 2023-05-16 | Cilag Gmbh International | Robotically-controlled motorized surgical instrument with an end effector |
US9005230B2 (en) | 2008-09-23 | 2015-04-14 | Ethicon Endo-Surgery, Inc. | Motorized surgical instrument |
US9386983B2 (en) | 2008-09-23 | 2016-07-12 | Ethicon Endo-Surgery, Llc | Robotically-controlled motorized surgical instrument |
US8210411B2 (en) | 2008-09-23 | 2012-07-03 | Ethicon Endo-Surgery, Inc. | Motor-driven surgical cutting instrument |
US8608045B2 (en) | 2008-10-10 | 2013-12-17 | Ethicon Endo-Sugery, Inc. | Powered surgical cutting and stapling apparatus with manually retractable firing system |
US8517239B2 (en) | 2009-02-05 | 2013-08-27 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument comprising a magnetic element driver |
CA2751664A1 (en) | 2009-02-06 | 2010-08-12 | Ethicon Endo-Surgery, Inc. | Driven surgical stapler improvements |
US8444036B2 (en) | 2009-02-06 | 2013-05-21 | Ethicon Endo-Surgery, Inc. | Motor driven surgical fastener device with mechanisms for adjusting a tissue gap within the end effector |
US8220688B2 (en) | 2009-12-24 | 2012-07-17 | Ethicon Endo-Surgery, Inc. | Motor-driven surgical cutting instrument with electric actuator directional control assembly |
US8851354B2 (en) | 2009-12-24 | 2014-10-07 | Ethicon Endo-Surgery, Inc. | Surgical cutting instrument that analyzes tissue thickness |
US8783543B2 (en) | 2010-07-30 | 2014-07-22 | Ethicon Endo-Surgery, Inc. | Tissue acquisition arrangements and methods for surgical stapling devices |
US9629814B2 (en) | 2010-09-30 | 2017-04-25 | Ethicon Endo-Surgery, Llc | Tissue thickness compensator configured to redistribute compressive forces |
US9320523B2 (en) | 2012-03-28 | 2016-04-26 | Ethicon Endo-Surgery, Llc | Tissue thickness compensator comprising tissue ingrowth features |
US11812965B2 (en) | 2010-09-30 | 2023-11-14 | Cilag Gmbh International | Layer of material for a surgical end effector |
US11298125B2 (en) | 2010-09-30 | 2022-04-12 | Cilag Gmbh International | Tissue stapler having a thickness compensator |
US9517063B2 (en) | 2012-03-28 | 2016-12-13 | Ethicon Endo-Surgery, Llc | Movable member for use with a tissue thickness compensator |
US11925354B2 (en) | 2010-09-30 | 2024-03-12 | Cilag Gmbh International | Staple cartridge comprising staples positioned within a compressible portion thereof |
US9364233B2 (en) | 2010-09-30 | 2016-06-14 | Ethicon Endo-Surgery, Llc | Tissue thickness compensators for circular surgical staplers |
US9351730B2 (en) | 2011-04-29 | 2016-05-31 | Ethicon Endo-Surgery, Llc | Tissue thickness compensator comprising channels |
US8864009B2 (en) | 2010-09-30 | 2014-10-21 | Ethicon Endo-Surgery, Inc. | Tissue thickness compensator for a surgical stapler comprising an adjustable anvil |
US10945731B2 (en) | 2010-09-30 | 2021-03-16 | Ethicon Llc | Tissue thickness compensator comprising controlled release and expansion |
US9592050B2 (en) | 2010-09-30 | 2017-03-14 | Ethicon Endo-Surgery, Llc | End effector comprising a distal tissue abutment member |
US8695866B2 (en) | 2010-10-01 | 2014-04-15 | Ethicon Endo-Surgery, Inc. | Surgical instrument having a power control circuit |
AU2012250197B2 (en) | 2011-04-29 | 2017-08-10 | Ethicon Endo-Surgery, Inc. | Staple cartridge comprising staples positioned within a compressible portion thereof |
US9072535B2 (en) | 2011-05-27 | 2015-07-07 | Ethicon Endo-Surgery, Inc. | Surgical stapling instruments with rotatable staple deployment arrangements |
US11207064B2 (en) | 2011-05-27 | 2021-12-28 | Cilag Gmbh International | Automated end effector component reloading system for use with a robotic system |
US9044230B2 (en) | 2012-02-13 | 2015-06-02 | Ethicon Endo-Surgery, Inc. | Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status |
CN104334098B (zh) | 2012-03-28 | 2017-03-22 | 伊西康内外科公司 | 包括限定低压强环境的胶囊剂的组织厚度补偿件 |
CN104379068B (zh) | 2012-03-28 | 2017-09-22 | 伊西康内外科公司 | 包括组织厚度补偿件的保持器组件 |
CN104321024B (zh) | 2012-03-28 | 2017-05-24 | 伊西康内外科公司 | 包括多个层的组织厚度补偿件 |
US11871901B2 (en) | 2012-05-20 | 2024-01-16 | Cilag Gmbh International | Method for situational awareness for surgical network or surgical network connected device capable of adjusting function based on a sensed situation or usage |
US9101358B2 (en) | 2012-06-15 | 2015-08-11 | Ethicon Endo-Surgery, Inc. | Articulatable surgical instrument comprising a firing drive |
US9282974B2 (en) | 2012-06-28 | 2016-03-15 | Ethicon Endo-Surgery, Llc | Empty clip cartridge lockout |
BR112014032776B1 (pt) | 2012-06-28 | 2021-09-08 | Ethicon Endo-Surgery, Inc | Sistema de instrumento cirúrgico e kit cirúrgico para uso com um sistema de instrumento cirúrgico |
US20140001231A1 (en) | 2012-06-28 | 2014-01-02 | Ethicon Endo-Surgery, Inc. | Firing system lockout arrangements for surgical instruments |
US11278284B2 (en) | 2012-06-28 | 2022-03-22 | Cilag Gmbh International | Rotary drive arrangements for surgical instruments |
US9204879B2 (en) | 2012-06-28 | 2015-12-08 | Ethicon Endo-Surgery, Inc. | Flexible drive member |
US9289256B2 (en) | 2012-06-28 | 2016-03-22 | Ethicon Endo-Surgery, Llc | Surgical end effectors having angled tissue-contacting surfaces |
US20140001234A1 (en) | 2012-06-28 | 2014-01-02 | Ethicon Endo-Surgery, Inc. | Coupling arrangements for attaching surgical end effectors to drive systems therefor |
RU2636861C2 (ru) | 2012-06-28 | 2017-11-28 | Этикон Эндо-Серджери, Инк. | Блокировка пустой кассеты с клипсами |
US9445816B2 (en) | 2012-12-17 | 2016-09-20 | Ethicon Endo-Surgery, Llc | Circular stapler with selectable motorized and manual control |
JP6345707B2 (ja) | 2013-03-01 | 2018-06-20 | エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. | ソフトストップを備えた外科用器具 |
RU2672520C2 (ru) | 2013-03-01 | 2018-11-15 | Этикон Эндо-Серджери, Инк. | Шарнирно поворачиваемые хирургические инструменты с проводящими путями для передачи сигналов |
US9888919B2 (en) | 2013-03-14 | 2018-02-13 | Ethicon Llc | Method and system for operating a surgical instrument |
US9629629B2 (en) | 2013-03-14 | 2017-04-25 | Ethicon Endo-Surgey, LLC | Control systems for surgical instruments |
WO2014153428A1 (en) | 2013-03-19 | 2014-09-25 | Surgisense Corporation | Apparatus, systems and methods for determining tissue oxygenation |
US9814460B2 (en) | 2013-04-16 | 2017-11-14 | Ethicon Llc | Modular motor driven surgical instruments with status indication arrangements |
BR112015026109B1 (pt) | 2013-04-16 | 2022-02-22 | Ethicon Endo-Surgery, Inc | Instrumento cirúrgico |
CN105530886B (zh) | 2013-08-09 | 2019-11-26 | 通用医疗公司 | 用于治疗真皮黄褐斑的方法和设备 |
MX369362B (es) | 2013-08-23 | 2019-11-06 | Ethicon Endo Surgery Llc | Dispositivos de retraccion de miembros de disparo para instrumentos quirurgicos electricos. |
US9283054B2 (en) | 2013-08-23 | 2016-03-15 | Ethicon Endo-Surgery, Llc | Interactive displays |
CA2965866A1 (en) | 2013-12-05 | 2015-06-11 | Veriskin, Inc. | Skin perfusion monitoring device |
US9962161B2 (en) | 2014-02-12 | 2018-05-08 | Ethicon Llc | Deliverable surgical instrument |
BR112016019387B1 (pt) | 2014-02-24 | 2022-11-29 | Ethicon Endo-Surgery, Llc | Sistema de instrumento cirúrgico e cartucho de prendedores para uso com um instrumento cirúrgico de fixação |
BR112016021943B1 (pt) | 2014-03-26 | 2022-06-14 | Ethicon Endo-Surgery, Llc | Instrumento cirúrgico para uso por um operador em um procedimento cirúrgico |
US10028761B2 (en) | 2014-03-26 | 2018-07-24 | Ethicon Llc | Feedback algorithms for manual bailout systems for surgical instruments |
US10004497B2 (en) | 2014-03-26 | 2018-06-26 | Ethicon Llc | Interface systems for use with surgical instruments |
US9826977B2 (en) | 2014-03-26 | 2017-11-28 | Ethicon Llc | Sterilization verification circuit |
CN106456158B (zh) | 2014-04-16 | 2019-02-05 | 伊西康内外科有限责任公司 | 包括非一致紧固件的紧固件仓 |
BR112016023698B1 (pt) | 2014-04-16 | 2022-07-26 | Ethicon Endo-Surgery, Llc | Cartucho de prendedores para uso com um instrumento cirúrgico |
US11517315B2 (en) | 2014-04-16 | 2022-12-06 | Cilag Gmbh International | Fastener cartridges including extensions having different configurations |
US9801628B2 (en) | 2014-09-26 | 2017-10-31 | Ethicon Llc | Surgical staple and driver arrangements for staple cartridges |
BR112016023807B1 (pt) | 2014-04-16 | 2022-07-12 | Ethicon Endo-Surgery, Llc | Conjunto de cartucho de prendedores para uso com um instrumento cirúrgico |
US20150297225A1 (en) | 2014-04-16 | 2015-10-22 | Ethicon Endo-Surgery, Inc. | Fastener cartridges including extensions having different configurations |
WO2016030726A1 (en) * | 2014-08-29 | 2016-03-03 | Synaptive Medical (Barbados) Inc. | Molecular cell imaging using optical spectroscopy |
BR112017004361B1 (pt) | 2014-09-05 | 2023-04-11 | Ethicon Llc | Sistema eletrônico para um instrumento cirúrgico |
US11311294B2 (en) | 2014-09-05 | 2022-04-26 | Cilag Gmbh International | Powered medical device including measurement of closure state of jaws |
US9724094B2 (en) | 2014-09-05 | 2017-08-08 | Ethicon Llc | Adjunct with integrated sensors to quantify tissue compression |
US10105142B2 (en) | 2014-09-18 | 2018-10-23 | Ethicon Llc | Surgical stapler with plurality of cutting elements |
BR112017005981B1 (pt) | 2014-09-26 | 2022-09-06 | Ethicon, Llc | Material de escora para uso com um cartucho de grampos cirúrgicos e cartucho de grampos cirúrgicos para uso com um instrumento cirúrgico |
US11523821B2 (en) | 2014-09-26 | 2022-12-13 | Cilag Gmbh International | Method for creating a flexible staple line |
US10076325B2 (en) | 2014-10-13 | 2018-09-18 | Ethicon Llc | Surgical stapling apparatus comprising a tissue stop |
US9924944B2 (en) | 2014-10-16 | 2018-03-27 | Ethicon Llc | Staple cartridge comprising an adjunct material |
US20160113516A1 (en) * | 2014-10-22 | 2016-04-28 | Walter Robert CARNES | Dental diagnostic device and method |
US10517594B2 (en) | 2014-10-29 | 2019-12-31 | Ethicon Llc | Cartridge assemblies for surgical staplers |
US11141153B2 (en) | 2014-10-29 | 2021-10-12 | Cilag Gmbh International | Staple cartridges comprising driver arrangements |
US11504192B2 (en) | 2014-10-30 | 2022-11-22 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
US9844376B2 (en) | 2014-11-06 | 2017-12-19 | Ethicon Llc | Staple cartridge comprising a releasable adjunct material |
US10736636B2 (en) | 2014-12-10 | 2020-08-11 | Ethicon Llc | Articulatable surgical instrument system |
BR112017012996B1 (pt) | 2014-12-18 | 2022-11-08 | Ethicon Llc | Instrumento cirúrgico com uma bigorna que é seletivamente móvel sobre um eixo geométrico imóvel distinto em relação a um cartucho de grampos |
US9987000B2 (en) | 2014-12-18 | 2018-06-05 | Ethicon Llc | Surgical instrument assembly comprising a flexible articulation system |
US9844375B2 (en) | 2014-12-18 | 2017-12-19 | Ethicon Llc | Drive arrangements for articulatable surgical instruments |
US10188385B2 (en) | 2014-12-18 | 2019-01-29 | Ethicon Llc | Surgical instrument system comprising lockable systems |
US10085748B2 (en) | 2014-12-18 | 2018-10-02 | Ethicon Llc | Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors |
US9844374B2 (en) | 2014-12-18 | 2017-12-19 | Ethicon Llc | Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member |
US9943309B2 (en) | 2014-12-18 | 2018-04-17 | Ethicon Llc | Surgical instruments with articulatable end effectors and movable firing beam support arrangements |
US9999759B2 (en) * | 2015-01-15 | 2018-06-19 | Ethicon, Inc. | Linear staplers having resorbable microneedles containing active agents |
US10792042B2 (en) * | 2015-01-15 | 2020-10-06 | Ethicon, Inc. | Circular staplers having resorbable microneedles containing active agents |
ES2907824T3 (es) * | 2015-02-19 | 2022-04-26 | Briteseed Llc | Sistema para determinar el borde de un vaso |
US10321907B2 (en) | 2015-02-27 | 2019-06-18 | Ethicon Llc | System for monitoring whether a surgical instrument needs to be serviced |
US10180463B2 (en) | 2015-02-27 | 2019-01-15 | Ethicon Llc | Surgical apparatus configured to assess whether a performance parameter of the surgical apparatus is within an acceptable performance band |
US11154301B2 (en) | 2015-02-27 | 2021-10-26 | Cilag Gmbh International | Modular stapling assembly |
US9901342B2 (en) | 2015-03-06 | 2018-02-27 | Ethicon Endo-Surgery, Llc | Signal and power communication system positioned on a rotatable shaft |
US10245033B2 (en) | 2015-03-06 | 2019-04-02 | Ethicon Llc | Surgical instrument comprising a lockable battery housing |
US10617412B2 (en) | 2015-03-06 | 2020-04-14 | Ethicon Llc | System for detecting the mis-insertion of a staple cartridge into a surgical stapler |
US10441279B2 (en) | 2015-03-06 | 2019-10-15 | Ethicon Llc | Multiple level thresholds to modify operation of powered surgical instruments |
US9924961B2 (en) | 2015-03-06 | 2018-03-27 | Ethicon Endo-Surgery, Llc | Interactive feedback system for powered surgical instruments |
US10052044B2 (en) | 2015-03-06 | 2018-08-21 | Ethicon Llc | Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures |
US9808246B2 (en) | 2015-03-06 | 2017-11-07 | Ethicon Endo-Surgery, Llc | Method of operating a powered surgical instrument |
US9993248B2 (en) | 2015-03-06 | 2018-06-12 | Ethicon Endo-Surgery, Llc | Smart sensors with local signal processing |
US10687806B2 (en) | 2015-03-06 | 2020-06-23 | Ethicon Llc | Adaptive tissue compression techniques to adjust closure rates for multiple tissue types |
JP2020121162A (ja) | 2015-03-06 | 2020-08-13 | エシコン エルエルシーEthicon LLC | 測定の安定性要素、クリープ要素、及び粘弾性要素を決定するためのセンサデータの時間依存性評価 |
US10213201B2 (en) | 2015-03-31 | 2019-02-26 | Ethicon Llc | Stapling end effector configured to compensate for an uneven gap between a first jaw and a second jaw |
WO2016168610A1 (en) | 2015-04-15 | 2016-10-20 | Nike, Inc. | Activity monitoring device with assessment of exercise intensity |
CN108025202B (zh) * | 2015-05-29 | 2021-07-02 | 耐克创新有限合伙公司 | 评估运动强度的活动监测设备 |
US11058425B2 (en) | 2015-08-17 | 2021-07-13 | Ethicon Llc | Implantable layers for a surgical instrument |
US10238386B2 (en) | 2015-09-23 | 2019-03-26 | Ethicon Llc | Surgical stapler having motor control based on an electrical parameter related to a motor current |
US10327769B2 (en) | 2015-09-23 | 2019-06-25 | Ethicon Llc | Surgical stapler having motor control based on a drive system component |
US10363036B2 (en) | 2015-09-23 | 2019-07-30 | Ethicon Llc | Surgical stapler having force-based motor control |
US10105139B2 (en) | 2015-09-23 | 2018-10-23 | Ethicon Llc | Surgical stapler having downstream current-based motor control |
US9987013B2 (en) * | 2015-09-24 | 2018-06-05 | Ethicon Llc | Surgical staple buttress with magnetic elements |
US10299878B2 (en) | 2015-09-25 | 2019-05-28 | Ethicon Llc | Implantable adjunct systems for determining adjunct skew |
US10736633B2 (en) | 2015-09-30 | 2020-08-11 | Ethicon Llc | Compressible adjunct with looping members |
US10980539B2 (en) | 2015-09-30 | 2021-04-20 | Ethicon Llc | Implantable adjunct comprising bonded layers |
US10524788B2 (en) | 2015-09-30 | 2020-01-07 | Ethicon Llc | Compressible adjunct with attachment regions |
US11890015B2 (en) | 2015-09-30 | 2024-02-06 | Cilag Gmbh International | Compressible adjunct with crossing spacer fibers |
US10624616B2 (en) * | 2015-12-18 | 2020-04-21 | Covidien Lp | Surgical instruments including sensors |
US10265068B2 (en) | 2015-12-30 | 2019-04-23 | Ethicon Llc | Surgical instruments with separable motors and motor control circuits |
US10292704B2 (en) | 2015-12-30 | 2019-05-21 | Ethicon Llc | Mechanisms for compensating for battery pack failure in powered surgical instruments |
US10368865B2 (en) | 2015-12-30 | 2019-08-06 | Ethicon Llc | Mechanisms for compensating for drivetrain failure in powered surgical instruments |
US10413291B2 (en) | 2016-02-09 | 2019-09-17 | Ethicon Llc | Surgical instrument articulation mechanism with slotted secondary constraint |
US11213293B2 (en) | 2016-02-09 | 2022-01-04 | Cilag Gmbh International | Articulatable surgical instruments with single articulation link arrangements |
CN108882932B (zh) | 2016-02-09 | 2021-07-23 | 伊西康有限责任公司 | 具有非对称关节运动构造的外科器械 |
US10448948B2 (en) | 2016-02-12 | 2019-10-22 | Ethicon Llc | Mechanisms for compensating for drivetrain failure in powered surgical instruments |
US11224426B2 (en) | 2016-02-12 | 2022-01-18 | Cilag Gmbh International | Mechanisms for compensating for drivetrain failure in powered surgical instruments |
US10258331B2 (en) | 2016-02-12 | 2019-04-16 | Ethicon Llc | Mechanisms for compensating for drivetrain failure in powered surgical instruments |
US10413297B2 (en) | 2016-04-01 | 2019-09-17 | Ethicon Llc | Surgical stapling system configured to apply annular rows of staples having different heights |
US10617413B2 (en) | 2016-04-01 | 2020-04-14 | Ethicon Llc | Closure system arrangements for surgical cutting and stapling devices with separate and distinct firing shafts |
US10456137B2 (en) | 2016-04-15 | 2019-10-29 | Ethicon Llc | Staple formation detection mechanisms |
US10492783B2 (en) | 2016-04-15 | 2019-12-03 | Ethicon, Llc | Surgical instrument with improved stop/start control during a firing motion |
US10335145B2 (en) | 2016-04-15 | 2019-07-02 | Ethicon Llc | Modular surgical instrument with configurable operating mode |
US10405859B2 (en) | 2016-04-15 | 2019-09-10 | Ethicon Llc | Surgical instrument with adjustable stop/start control during a firing motion |
US10357247B2 (en) | 2016-04-15 | 2019-07-23 | Ethicon Llc | Surgical instrument with multiple program responses during a firing motion |
US10426467B2 (en) | 2016-04-15 | 2019-10-01 | Ethicon Llc | Surgical instrument with detection sensors |
US11179150B2 (en) | 2016-04-15 | 2021-11-23 | Cilag Gmbh International | Systems and methods for controlling a surgical stapling and cutting instrument |
US10828028B2 (en) | 2016-04-15 | 2020-11-10 | Ethicon Llc | Surgical instrument with multiple program responses during a firing motion |
US11607239B2 (en) | 2016-04-15 | 2023-03-21 | Cilag Gmbh International | Systems and methods for controlling a surgical stapling and cutting instrument |
US11317917B2 (en) | 2016-04-18 | 2022-05-03 | Cilag Gmbh International | Surgical stapling system comprising a lockable firing assembly |
US10363037B2 (en) | 2016-04-18 | 2019-07-30 | Ethicon Llc | Surgical instrument system comprising a magnetic lockout |
US20170296173A1 (en) | 2016-04-18 | 2017-10-19 | Ethicon Endo-Surgery, Llc | Method for operating a surgical instrument |
US10722158B2 (en) | 2016-04-20 | 2020-07-28 | Vioptix, Inc. | Handheld oximeter probe with replaceable probe tip |
TWI730080B (zh) | 2016-04-20 | 2021-06-11 | 美商菲歐普提斯公司 | 可執行電子選擇式組織深度分析之血氧計探針 |
TWI765885B (zh) | 2016-04-21 | 2022-06-01 | 美商菲歐普提斯公司 | 利用黑色素校正之測定組織氧飽和度的方法和裝置 |
EP4162873A1 (en) | 2016-04-22 | 2023-04-12 | Vioptix, Inc. | Determining absolute and relative tissue oxygen saturation |
TWI754641B (zh) | 2016-04-22 | 2022-02-11 | 美商菲歐普提斯公司 | 血氧計裝置及具有此裝置之血氧計系統 |
US10499912B2 (en) * | 2016-07-13 | 2019-12-10 | Ethicon Llc | Apparatus for hydraulic assisted fracture of liver parenchyma |
EP3484366A4 (en) | 2016-07-18 | 2020-10-14 | Vioptix, Inc. | OXIMETRY DEVICE WITH LAPAROSCOPIC EXTENSION |
KR101838188B1 (ko) * | 2016-10-31 | 2018-03-13 | 비앤알(주) | 원형 문합기 |
US11419606B2 (en) | 2016-12-21 | 2022-08-23 | Cilag Gmbh International | Shaft assembly comprising a clutch configured to adapt the output of a rotary firing member to two different systems |
BR112019011947A2 (pt) | 2016-12-21 | 2019-10-29 | Ethicon Llc | sistemas de grampeamento cirúrgico |
US10426471B2 (en) | 2016-12-21 | 2019-10-01 | Ethicon Llc | Surgical instrument with multiple failure response modes |
US10542982B2 (en) | 2016-12-21 | 2020-01-28 | Ethicon Llc | Shaft assembly comprising first and second articulation lockouts |
US20180168625A1 (en) | 2016-12-21 | 2018-06-21 | Ethicon Endo-Surgery, Llc | Surgical stapling instruments with smart staple cartridges |
US10758229B2 (en) | 2016-12-21 | 2020-09-01 | Ethicon Llc | Surgical instrument comprising improved jaw control |
US10588630B2 (en) | 2016-12-21 | 2020-03-17 | Ethicon Llc | Surgical tool assemblies with closure stroke reduction features |
US10893864B2 (en) | 2016-12-21 | 2021-01-19 | Ethicon | Staple cartridges and arrangements of staples and staple cavities therein |
CN110099619B (zh) | 2016-12-21 | 2022-07-15 | 爱惜康有限责任公司 | 用于外科端部执行器和可替换工具组件的闭锁装置 |
US20180168615A1 (en) | 2016-12-21 | 2018-06-21 | Ethicon Endo-Surgery, Llc | Method of deforming staples from two different types of staple cartridges with the same surgical stapling instrument |
US10639035B2 (en) | 2016-12-21 | 2020-05-05 | Ethicon Llc | Surgical stapling instruments and replaceable tool assemblies thereof |
JP7010956B2 (ja) | 2016-12-21 | 2022-01-26 | エシコン エルエルシー | 組織をステープル留めする方法 |
US10485543B2 (en) | 2016-12-21 | 2019-11-26 | Ethicon Llc | Anvil having a knife slot width |
US10695055B2 (en) | 2016-12-21 | 2020-06-30 | Ethicon Llc | Firing assembly comprising a lockout |
US20180168618A1 (en) | 2016-12-21 | 2018-06-21 | Ethicon Endo-Surgery, Llc | Surgical stapling systems |
US11134942B2 (en) | 2016-12-21 | 2021-10-05 | Cilag Gmbh International | Surgical stapling instruments and staple-forming anvils |
US10667810B2 (en) | 2016-12-21 | 2020-06-02 | Ethicon Llc | Closure members with cam surface arrangements for surgical instruments with separate and distinct closure and firing systems |
US20180168598A1 (en) | 2016-12-21 | 2018-06-21 | Ethicon Endo-Surgery, Llc | Staple forming pocket arrangements comprising zoned forming surface grooves |
US11090048B2 (en) | 2016-12-21 | 2021-08-17 | Cilag Gmbh International | Method for resetting a fuse of a surgical instrument shaft |
CN106725520A (zh) * | 2016-12-31 | 2017-05-31 | 中国科学院苏州生物医学工程技术研究所 | 脑血氧检测的信号处理方法系统 |
US10638944B2 (en) | 2017-02-22 | 2020-05-05 | Covidien Lp | Methods of determining tissue viability |
US10687811B2 (en) | 2017-03-08 | 2020-06-23 | Covidien Lp | Surgical instruments including sensors |
US20180256161A1 (en) * | 2017-03-08 | 2018-09-13 | Covidien Lp | Surgical instruments including sensors |
US11096610B2 (en) | 2017-03-28 | 2021-08-24 | Covidien Lp | Surgical implants including sensing fibers |
US10945616B2 (en) * | 2017-05-12 | 2021-03-16 | Covidien Lp | Blood pressure measuring surgical instrument |
US10813639B2 (en) | 2017-06-20 | 2020-10-27 | Ethicon Llc | Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on system conditions |
US11090046B2 (en) | 2017-06-20 | 2021-08-17 | Cilag Gmbh International | Systems and methods for controlling displacement member motion of a surgical stapling and cutting instrument |
USD879809S1 (en) | 2017-06-20 | 2020-03-31 | Ethicon Llc | Display panel with changeable graphical user interface |
US10779820B2 (en) | 2017-06-20 | 2020-09-22 | Ethicon Llc | Systems and methods for controlling motor speed according to user input for a surgical instrument |
US11071554B2 (en) | 2017-06-20 | 2021-07-27 | Cilag Gmbh International | Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on magnitude of velocity error measurements |
US10307170B2 (en) | 2017-06-20 | 2019-06-04 | Ethicon Llc | Method for closed loop control of motor velocity of a surgical stapling and cutting instrument |
US10327767B2 (en) | 2017-06-20 | 2019-06-25 | Ethicon Llc | Control of motor velocity of a surgical stapling and cutting instrument based on angle of articulation |
US10881399B2 (en) | 2017-06-20 | 2021-01-05 | Ethicon Llc | Techniques for adaptive control of motor velocity of a surgical stapling and cutting instrument |
US11653914B2 (en) | 2017-06-20 | 2023-05-23 | Cilag Gmbh International | Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument according to articulation angle of end effector |
US10390841B2 (en) | 2017-06-20 | 2019-08-27 | Ethicon Llc | Control of motor velocity of a surgical stapling and cutting instrument based on angle of articulation |
US11382638B2 (en) | 2017-06-20 | 2022-07-12 | Cilag Gmbh International | Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified displacement distance |
US10881396B2 (en) | 2017-06-20 | 2021-01-05 | Ethicon Llc | Surgical instrument with variable duration trigger arrangement |
USD879808S1 (en) | 2017-06-20 | 2020-03-31 | Ethicon Llc | Display panel with graphical user interface |
US10888321B2 (en) | 2017-06-20 | 2021-01-12 | Ethicon Llc | Systems and methods for controlling velocity of a displacement member of a surgical stapling and cutting instrument |
USD890784S1 (en) | 2017-06-20 | 2020-07-21 | Ethicon Llc | Display panel with changeable graphical user interface |
US10624633B2 (en) | 2017-06-20 | 2020-04-21 | Ethicon Llc | Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument |
US11517325B2 (en) | 2017-06-20 | 2022-12-06 | Cilag Gmbh International | Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured displacement distance traveled over a specified time interval |
US10646220B2 (en) | 2017-06-20 | 2020-05-12 | Ethicon Llc | Systems and methods for controlling displacement member velocity for a surgical instrument |
US10368864B2 (en) | 2017-06-20 | 2019-08-06 | Ethicon Llc | Systems and methods for controlling displaying motor velocity for a surgical instrument |
US10980537B2 (en) | 2017-06-20 | 2021-04-20 | Ethicon Llc | Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified number of shaft rotations |
US10993716B2 (en) | 2017-06-27 | 2021-05-04 | Ethicon Llc | Surgical anvil arrangements |
US11141154B2 (en) | 2017-06-27 | 2021-10-12 | Cilag Gmbh International | Surgical end effectors and anvils |
US11266405B2 (en) | 2017-06-27 | 2022-03-08 | Cilag Gmbh International | Surgical anvil manufacturing methods |
US10856869B2 (en) | 2017-06-27 | 2020-12-08 | Ethicon Llc | Surgical anvil arrangements |
US11324503B2 (en) | 2017-06-27 | 2022-05-10 | Cilag Gmbh International | Surgical firing member arrangements |
US10772629B2 (en) | 2017-06-27 | 2020-09-15 | Ethicon Llc | Surgical anvil arrangements |
US10765427B2 (en) | 2017-06-28 | 2020-09-08 | Ethicon Llc | Method for articulating a surgical instrument |
USD851762S1 (en) | 2017-06-28 | 2019-06-18 | Ethicon Llc | Anvil |
USD906355S1 (en) | 2017-06-28 | 2020-12-29 | Ethicon Llc | Display screen or portion thereof with a graphical user interface for a surgical instrument |
US10716614B2 (en) | 2017-06-28 | 2020-07-21 | Ethicon Llc | Surgical shaft assemblies with slip ring assemblies with increased contact pressure |
US11564686B2 (en) | 2017-06-28 | 2023-01-31 | Cilag Gmbh International | Surgical shaft assemblies with flexible interfaces |
US11246592B2 (en) | 2017-06-28 | 2022-02-15 | Cilag Gmbh International | Surgical instrument comprising an articulation system lockable to a frame |
USD854151S1 (en) | 2017-06-28 | 2019-07-16 | Ethicon Llc | Surgical instrument shaft |
US10211586B2 (en) | 2017-06-28 | 2019-02-19 | Ethicon Llc | Surgical shaft assemblies with watertight housings |
US11000279B2 (en) | 2017-06-28 | 2021-05-11 | Ethicon Llc | Surgical instrument comprising an articulation system ratio |
US10786253B2 (en) | 2017-06-28 | 2020-09-29 | Ethicon Llc | Surgical end effectors with improved jaw aperture arrangements |
EP3420947B1 (en) | 2017-06-28 | 2022-05-25 | Cilag GmbH International | Surgical instrument comprising selectively actuatable rotatable couplers |
USD869655S1 (en) | 2017-06-28 | 2019-12-10 | Ethicon Llc | Surgical fastener cartridge |
US11259805B2 (en) | 2017-06-28 | 2022-03-01 | Cilag Gmbh International | Surgical instrument comprising firing member supports |
US10903685B2 (en) | 2017-06-28 | 2021-01-26 | Ethicon Llc | Surgical shaft assemblies with slip ring assemblies forming capacitive channels |
US10898183B2 (en) | 2017-06-29 | 2021-01-26 | Ethicon Llc | Robotic surgical instrument with closed loop feedback techniques for advancement of closure member during firing |
US11007022B2 (en) | 2017-06-29 | 2021-05-18 | Ethicon Llc | Closed loop velocity control techniques based on sensed tissue parameters for robotic surgical instrument |
US10932772B2 (en) | 2017-06-29 | 2021-03-02 | Ethicon Llc | Methods for closed loop velocity control for robotic surgical instrument |
US10258418B2 (en) | 2017-06-29 | 2019-04-16 | Ethicon Llc | System for controlling articulation forces |
US10398434B2 (en) | 2017-06-29 | 2019-09-03 | Ethicon Llc | Closed loop velocity control of closure member for robotic surgical instrument |
CA3004066A1 (en) * | 2017-06-29 | 2018-12-29 | Covidien Lp | Surgical instruments including sensors |
US11471155B2 (en) | 2017-08-03 | 2022-10-18 | Cilag Gmbh International | Surgical system bailout |
US11944300B2 (en) | 2017-08-03 | 2024-04-02 | Cilag Gmbh International | Method for operating a surgical system bailout |
US11304695B2 (en) | 2017-08-03 | 2022-04-19 | Cilag Gmbh International | Surgical system shaft interconnection |
US11974742B2 (en) | 2017-08-03 | 2024-05-07 | Cilag Gmbh International | Surgical system comprising an articulation bailout |
US10743872B2 (en) | 2017-09-29 | 2020-08-18 | Ethicon Llc | System and methods for controlling a display of a surgical instrument |
US10796471B2 (en) | 2017-09-29 | 2020-10-06 | Ethicon Llc | Systems and methods of displaying a knife position for a surgical instrument |
US10729501B2 (en) | 2017-09-29 | 2020-08-04 | Ethicon Llc | Systems and methods for language selection of a surgical instrument |
USD917500S1 (en) | 2017-09-29 | 2021-04-27 | Ethicon Llc | Display screen or portion thereof with graphical user interface |
USD907648S1 (en) | 2017-09-29 | 2021-01-12 | Ethicon Llc | Display screen or portion thereof with animated graphical user interface |
US11399829B2 (en) | 2017-09-29 | 2022-08-02 | Cilag Gmbh International | Systems and methods of initiating a power shutdown mode for a surgical instrument |
USD907647S1 (en) | 2017-09-29 | 2021-01-12 | Ethicon Llc | Display screen or portion thereof with animated graphical user interface |
US10765429B2 (en) | 2017-09-29 | 2020-09-08 | Ethicon Llc | Systems and methods for providing alerts according to the operational state of a surgical instrument |
GB2567848B (en) * | 2017-10-26 | 2020-05-27 | Ndm Technologies Ltd | Injection device |
US11134944B2 (en) | 2017-10-30 | 2021-10-05 | Cilag Gmbh International | Surgical stapler knife motion controls |
US11317919B2 (en) | 2017-10-30 | 2022-05-03 | Cilag Gmbh International | Clip applier comprising a clip crimping system |
US11123070B2 (en) | 2017-10-30 | 2021-09-21 | Cilag Gmbh International | Clip applier comprising a rotatable clip magazine |
US11026712B2 (en) | 2017-10-30 | 2021-06-08 | Cilag Gmbh International | Surgical instruments comprising a shifting mechanism |
US11911045B2 (en) | 2017-10-30 | 2024-02-27 | Cllag GmbH International | Method for operating a powered articulating multi-clip applier |
US11564756B2 (en) | 2017-10-30 | 2023-01-31 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
US11311342B2 (en) | 2017-10-30 | 2022-04-26 | Cilag Gmbh International | Method for communicating with surgical instrument systems |
US11229436B2 (en) | 2017-10-30 | 2022-01-25 | Cilag Gmbh International | Surgical system comprising a surgical tool and a surgical hub |
US11801098B2 (en) | 2017-10-30 | 2023-10-31 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
US11090075B2 (en) | 2017-10-30 | 2021-08-17 | Cilag Gmbh International | Articulation features for surgical end effector |
US11291510B2 (en) | 2017-10-30 | 2022-04-05 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
US11510741B2 (en) | 2017-10-30 | 2022-11-29 | Cilag Gmbh International | Method for producing a surgical instrument comprising a smart electrical system |
US10779903B2 (en) | 2017-10-31 | 2020-09-22 | Ethicon Llc | Positive shaft rotation lock activated by jaw closure |
US10842490B2 (en) | 2017-10-31 | 2020-11-24 | Ethicon Llc | Cartridge body design with force reduction based on firing completion |
US11547439B2 (en) * | 2017-12-12 | 2023-01-10 | Covidien Lp | Surgical instruments including devices for sensing tissue properties and methods thereof |
US11006955B2 (en) | 2017-12-15 | 2021-05-18 | Ethicon Llc | End effectors with positive jaw opening features for use with adapters for electromechanical surgical instruments |
US10828033B2 (en) | 2017-12-15 | 2020-11-10 | Ethicon Llc | Handheld electromechanical surgical instruments with improved motor control arrangements for positioning components of an adapter coupled thereto |
US10869666B2 (en) | 2017-12-15 | 2020-12-22 | Ethicon Llc | Adapters with control systems for controlling multiple motors of an electromechanical surgical instrument |
US10779826B2 (en) | 2017-12-15 | 2020-09-22 | Ethicon Llc | Methods of operating surgical end effectors |
US10779825B2 (en) | 2017-12-15 | 2020-09-22 | Ethicon Llc | Adapters with end effector position sensing and control arrangements for use in connection with electromechanical surgical instruments |
US10966718B2 (en) | 2017-12-15 | 2021-04-06 | Ethicon Llc | Dynamic clamping assemblies with improved wear characteristics for use in connection with electromechanical surgical instruments |
US11197670B2 (en) | 2017-12-15 | 2021-12-14 | Cilag Gmbh International | Surgical end effectors with pivotal jaws configured to touch at their respective distal ends when fully closed |
US11071543B2 (en) | 2017-12-15 | 2021-07-27 | Cilag Gmbh International | Surgical end effectors with clamping assemblies configured to increase jaw aperture ranges |
US10743874B2 (en) | 2017-12-15 | 2020-08-18 | Ethicon Llc | Sealed adapters for use with electromechanical surgical instruments |
US11033267B2 (en) | 2017-12-15 | 2021-06-15 | Ethicon Llc | Systems and methods of controlling a clamping member firing rate of a surgical instrument |
US10743875B2 (en) | 2017-12-15 | 2020-08-18 | Ethicon Llc | Surgical end effectors with jaw stiffener arrangements configured to permit monitoring of firing member |
US10687813B2 (en) | 2017-12-15 | 2020-06-23 | Ethicon Llc | Adapters with firing stroke sensing arrangements for use in connection with electromechanical surgical instruments |
US11020112B2 (en) | 2017-12-19 | 2021-06-01 | Ethicon Llc | Surgical tools configured for interchangeable use with different controller interfaces |
US10729509B2 (en) | 2017-12-19 | 2020-08-04 | Ethicon Llc | Surgical instrument comprising closure and firing locking mechanism |
US10716565B2 (en) | 2017-12-19 | 2020-07-21 | Ethicon Llc | Surgical instruments with dual articulation drivers |
US11045270B2 (en) | 2017-12-19 | 2021-06-29 | Cilag Gmbh International | Robotic attachment comprising exterior drive actuator |
US10835330B2 (en) | 2017-12-19 | 2020-11-17 | Ethicon Llc | Method for determining the position of a rotatable jaw of a surgical instrument attachment assembly |
USD910847S1 (en) | 2017-12-19 | 2021-02-16 | Ethicon Llc | Surgical instrument assembly |
US11076853B2 (en) | 2017-12-21 | 2021-08-03 | Cilag Gmbh International | Systems and methods of displaying a knife position during transection for a surgical instrument |
US11311290B2 (en) | 2017-12-21 | 2022-04-26 | Cilag Gmbh International | Surgical instrument comprising an end effector dampener |
US10682134B2 (en) | 2017-12-21 | 2020-06-16 | Ethicon Llc | Continuous use self-propelled stapling instrument |
US11129680B2 (en) | 2017-12-21 | 2021-09-28 | Cilag Gmbh International | Surgical instrument comprising a projector |
US10966791B2 (en) | 2017-12-28 | 2021-04-06 | Ethicon Llc | Cloud-based medical analytics for medical facility segmented individualization of instrument function |
US11937769B2 (en) | 2017-12-28 | 2024-03-26 | Cilag Gmbh International | Method of hub communication, processing, storage and display |
US11376002B2 (en) | 2017-12-28 | 2022-07-05 | Cilag Gmbh International | Surgical instrument cartridge sensor assemblies |
US11559308B2 (en) | 2017-12-28 | 2023-01-24 | Cilag Gmbh International | Method for smart energy device infrastructure |
US11666331B2 (en) | 2017-12-28 | 2023-06-06 | Cilag Gmbh International | Systems for detecting proximity of surgical end effector to cancerous tissue |
US10987178B2 (en) | 2017-12-28 | 2021-04-27 | Ethicon Llc | Surgical hub control arrangements |
US11540855B2 (en) | 2017-12-28 | 2023-01-03 | Cilag Gmbh International | Controlling activation of an ultrasonic surgical instrument according to the presence of tissue |
US11051876B2 (en) | 2017-12-28 | 2021-07-06 | Cilag Gmbh International | Surgical evacuation flow paths |
US11832899B2 (en) | 2017-12-28 | 2023-12-05 | Cilag Gmbh International | Surgical systems with autonomously adjustable control programs |
US11419667B2 (en) | 2017-12-28 | 2022-08-23 | Cilag Gmbh International | Ultrasonic energy device which varies pressure applied by clamp arm to provide threshold control pressure at a cut progression location |
US20190200980A1 (en) * | 2017-12-28 | 2019-07-04 | Ethicon Llc | Surgical system for presenting information interpreted from external data |
US11266468B2 (en) | 2017-12-28 | 2022-03-08 | Cilag Gmbh International | Cooperative utilization of data derived from secondary sources by intelligent surgical hubs |
US11571234B2 (en) | 2017-12-28 | 2023-02-07 | Cilag Gmbh International | Temperature control of ultrasonic end effector and control system therefor |
US10849697B2 (en) | 2017-12-28 | 2020-12-01 | Ethicon Llc | Cloud interface for coupled surgical devices |
US11832840B2 (en) | 2017-12-28 | 2023-12-05 | Cilag Gmbh International | Surgical instrument having a flexible circuit |
US11304745B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Surgical evacuation sensing and display |
US11166772B2 (en) | 2017-12-28 | 2021-11-09 | Cilag Gmbh International | Surgical hub coordination of control and communication of operating room devices |
US20190201039A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Situational awareness of electrosurgical systems |
US11100631B2 (en) | 2017-12-28 | 2021-08-24 | Cilag Gmbh International | Use of laser light and red-green-blue coloration to determine properties of back scattered light |
US11559307B2 (en) | 2017-12-28 | 2023-01-24 | Cilag Gmbh International | Method of robotic hub communication, detection, and control |
US11464559B2 (en) | 2017-12-28 | 2022-10-11 | Cilag Gmbh International | Estimating state of ultrasonic end effector and control system therefor |
US10758310B2 (en) | 2017-12-28 | 2020-09-01 | Ethicon Llc | Wireless pairing of a surgical device with another device within a sterile surgical field based on the usage and situational awareness of devices |
US11633237B2 (en) | 2017-12-28 | 2023-04-25 | Cilag Gmbh International | Usage and technique analysis of surgeon / staff performance against a baseline to optimize device utilization and performance for both current and future procedures |
US11529187B2 (en) | 2017-12-28 | 2022-12-20 | Cilag Gmbh International | Surgical evacuation sensor arrangements |
US10695081B2 (en) | 2017-12-28 | 2020-06-30 | Ethicon Llc | Controlling a surgical instrument according to sensed closure parameters |
US11969216B2 (en) | 2017-12-28 | 2024-04-30 | Cilag Gmbh International | Surgical network recommendations from real time analysis of procedure variables against a baseline highlighting differences from the optimal solution |
US11864728B2 (en) | 2017-12-28 | 2024-01-09 | Cilag Gmbh International | Characterization of tissue irregularities through the use of mono-chromatic light refractivity |
US11857152B2 (en) | 2017-12-28 | 2024-01-02 | Cilag Gmbh International | Surgical hub spatial awareness to determine devices in operating theater |
US11744604B2 (en) | 2017-12-28 | 2023-09-05 | Cilag Gmbh International | Surgical instrument with a hardware-only control circuit |
US11432885B2 (en) | 2017-12-28 | 2022-09-06 | Cilag Gmbh International | Sensing arrangements for robot-assisted surgical platforms |
US11308075B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Surgical network, instrument, and cloud responses based on validation of received dataset and authentication of its source and integrity |
US11213359B2 (en) | 2017-12-28 | 2022-01-04 | Cilag Gmbh International | Controllers for robot-assisted surgical platforms |
US11896322B2 (en) | 2017-12-28 | 2024-02-13 | Cilag Gmbh International | Sensing the patient position and contact utilizing the mono-polar return pad electrode to provide situational awareness to the hub |
US11311306B2 (en) | 2017-12-28 | 2022-04-26 | Cilag Gmbh International | Surgical systems for detecting end effector tissue distribution irregularities |
US11464535B2 (en) | 2017-12-28 | 2022-10-11 | Cilag Gmbh International | Detection of end effector emersion in liquid |
US20190201139A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Communication arrangements for robot-assisted surgical platforms |
US20190201087A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Smoke evacuation system including a segmented control circuit for interactive surgical platform |
US11317937B2 (en) | 2018-03-08 | 2022-05-03 | Cilag Gmbh International | Determining the state of an ultrasonic end effector |
US10932872B2 (en) | 2017-12-28 | 2021-03-02 | Ethicon Llc | Cloud-based medical analytics for linking of local usage trends with the resource acquisition behaviors of larger data set |
US11424027B2 (en) | 2017-12-28 | 2022-08-23 | Cilag Gmbh International | Method for operating surgical instrument systems |
US11147607B2 (en) | 2017-12-28 | 2021-10-19 | Cilag Gmbh International | Bipolar combination device that automatically adjusts pressure based on energy modality |
US11179208B2 (en) | 2017-12-28 | 2021-11-23 | Cilag Gmbh International | Cloud-based medical analytics for security and authentication trends and reactive measures |
US11659023B2 (en) | 2017-12-28 | 2023-05-23 | Cilag Gmbh International | Method of hub communication |
US11896443B2 (en) | 2017-12-28 | 2024-02-13 | Cilag Gmbh International | Control of a surgical system through a surgical barrier |
US10892995B2 (en) | 2017-12-28 | 2021-01-12 | Ethicon Llc | Surgical network determination of prioritization of communication, interaction, or processing based on system or device needs |
US11096693B2 (en) | 2017-12-28 | 2021-08-24 | Cilag Gmbh International | Adjustment of staple height of at least one row of staples based on the sensed tissue thickness or force in closing |
US11389164B2 (en) | 2017-12-28 | 2022-07-19 | Cilag Gmbh International | Method of using reinforced flexible circuits with multiple sensors to optimize performance of radio frequency devices |
US11364075B2 (en) | 2017-12-28 | 2022-06-21 | Cilag Gmbh International | Radio frequency energy device for delivering combined electrical signals |
US11410259B2 (en) | 2017-12-28 | 2022-08-09 | Cilag Gmbh International | Adaptive control program updates for surgical devices |
US11304763B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Image capturing of the areas outside the abdomen to improve placement and control of a surgical device in use |
US11253315B2 (en) | 2017-12-28 | 2022-02-22 | Cilag Gmbh International | Increasing radio frequency to create pad-less monopolar loop |
US11026751B2 (en) | 2017-12-28 | 2021-06-08 | Cilag Gmbh International | Display of alignment of staple cartridge to prior linear staple line |
US11576677B2 (en) | 2017-12-28 | 2023-02-14 | Cilag Gmbh International | Method of hub communication, processing, display, and cloud analytics |
US10898622B2 (en) | 2017-12-28 | 2021-01-26 | Ethicon Llc | Surgical evacuation system with a communication circuit for communication between a filter and a smoke evacuation device |
US11278281B2 (en) | 2017-12-28 | 2022-03-22 | Cilag Gmbh International | Interactive surgical system |
US11202570B2 (en) | 2017-12-28 | 2021-12-21 | Cilag Gmbh International | Communication hub and storage device for storing parameters and status of a surgical device to be shared with cloud based analytics systems |
US11969142B2 (en) | 2017-12-28 | 2024-04-30 | Cilag Gmbh International | Method of compressing tissue within a stapling device and simultaneously displaying the location of the tissue within the jaws |
US11786251B2 (en) | 2017-12-28 | 2023-10-17 | Cilag Gmbh International | Method for adaptive control schemes for surgical network control and interaction |
US11160605B2 (en) | 2017-12-28 | 2021-11-02 | Cilag Gmbh International | Surgical evacuation sensing and motor control |
US11304720B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Activation of energy devices |
US10944728B2 (en) | 2017-12-28 | 2021-03-09 | Ethicon Llc | Interactive surgical systems with encrypted communication capabilities |
US11076921B2 (en) | 2017-12-28 | 2021-08-03 | Cilag Gmbh International | Adaptive control program updates for surgical hubs |
US20190201042A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Determining the state of an ultrasonic electromechanical system according to frequency shift |
US11291495B2 (en) | 2017-12-28 | 2022-04-05 | Cilag Gmbh International | Interruption of energy due to inadvertent capacitive coupling |
US11056244B2 (en) | 2017-12-28 | 2021-07-06 | Cilag Gmbh International | Automated data scaling, alignment, and organizing based on predefined parameters within surgical networks |
US10943454B2 (en) | 2017-12-28 | 2021-03-09 | Ethicon Llc | Detection and escalation of security responses of surgical instruments to increasing severity threats |
US11786245B2 (en) | 2017-12-28 | 2023-10-17 | Cilag Gmbh International | Surgical systems with prioritized data transmission capabilities |
US11446052B2 (en) | 2017-12-28 | 2022-09-20 | Cilag Gmbh International | Variation of radio frequency and ultrasonic power level in cooperation with varying clamp arm pressure to achieve predefined heat flux or power applied to tissue |
US11696760B2 (en) | 2017-12-28 | 2023-07-11 | Cilag Gmbh International | Safety systems for smart powered surgical stapling |
US11678881B2 (en) | 2017-12-28 | 2023-06-20 | Cilag Gmbh International | Spatial awareness of surgical hubs in operating rooms |
US11304699B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Method for adaptive control schemes for surgical network control and interaction |
US11903601B2 (en) | 2017-12-28 | 2024-02-20 | Cilag Gmbh International | Surgical instrument comprising a plurality of drive systems |
US11818052B2 (en) | 2017-12-28 | 2023-11-14 | Cilag Gmbh International | Surgical network determination of prioritization of communication, interaction, or processing based on system or device needs |
US11602393B2 (en) | 2017-12-28 | 2023-03-14 | Cilag Gmbh International | Surgical evacuation sensing and generator control |
US11419630B2 (en) | 2017-12-28 | 2022-08-23 | Cilag Gmbh International | Surgical system distributed processing |
US11612444B2 (en) | 2017-12-28 | 2023-03-28 | Cilag Gmbh International | Adjustment of a surgical device function based on situational awareness |
US11257589B2 (en) | 2017-12-28 | 2022-02-22 | Cilag Gmbh International | Real-time analysis of comprehensive cost of all instrumentation used in surgery utilizing data fluidity to track instruments through stocking and in-house processes |
JP7330980B2 (ja) | 2017-12-28 | 2023-08-22 | エシコン エルエルシー | 外部データから解釈された情報を提示するための外科用システム |
US11109866B2 (en) | 2017-12-28 | 2021-09-07 | Cilag Gmbh International | Method for circular stapler control algorithm adjustment based on situational awareness |
US10892899B2 (en) | 2017-12-28 | 2021-01-12 | Ethicon Llc | Self describing data packets generated at an issuing instrument |
US11273001B2 (en) | 2017-12-28 | 2022-03-15 | Cilag Gmbh International | Surgical hub and modular device response adjustment based on situational awareness |
US11423007B2 (en) | 2017-12-28 | 2022-08-23 | Cilag Gmbh International | Adjustment of device control programs based on stratified contextual data in addition to the data |
US11589888B2 (en) | 2017-12-28 | 2023-02-28 | Cilag Gmbh International | Method for controlling smart energy devices |
US11069012B2 (en) | 2017-12-28 | 2021-07-20 | Cilag Gmbh International | Interactive surgical systems with condition handling of devices and data capabilities |
US11284936B2 (en) | 2017-12-28 | 2022-03-29 | Cilag Gmbh International | Surgical instrument having a flexible electrode |
US11234756B2 (en) | 2017-12-28 | 2022-02-01 | Cilag Gmbh International | Powered surgical tool with predefined adjustable control algorithm for controlling end effector parameter |
US11324557B2 (en) | 2017-12-28 | 2022-05-10 | Cilag Gmbh International | Surgical instrument with a sensing array |
US11132462B2 (en) | 2017-12-28 | 2021-09-28 | Cilag Gmbh International | Data stripping method to interrogate patient records and create anonymized record |
NL2020240B1 (en) * | 2018-01-05 | 2019-07-12 | Veenhof Medical Devices B V | Testing tissue viability for an anastomosis |
US20190246985A1 (en) * | 2018-02-13 | 2019-08-15 | Covidien Lp | Clamping device for detecting internal blood pressure |
WO2019165554A1 (en) | 2018-03-01 | 2019-09-06 | Archeoptix Biomedical Inc. | System for intracranial imaging and treatment |
US11534196B2 (en) | 2018-03-08 | 2022-12-27 | Cilag Gmbh International | Using spectroscopy to determine device use state in combo instrument |
US11678927B2 (en) | 2018-03-08 | 2023-06-20 | Cilag Gmbh International | Detection of large vessels during parenchymal dissection using a smart blade |
US11259830B2 (en) | 2018-03-08 | 2022-03-01 | Cilag Gmbh International | Methods for controlling temperature in ultrasonic device |
US10973520B2 (en) | 2018-03-28 | 2021-04-13 | Ethicon Llc | Surgical staple cartridge with firing member driven camming assembly that has an onboard tissue cutting feature |
US11096688B2 (en) | 2018-03-28 | 2021-08-24 | Cilag Gmbh International | Rotary driven firing members with different anvil and channel engagement features |
US11471156B2 (en) | 2018-03-28 | 2022-10-18 | Cilag Gmbh International | Surgical stapling devices with improved rotary driven closure systems |
US11207067B2 (en) | 2018-03-28 | 2021-12-28 | Cilag Gmbh International | Surgical stapling device with separate rotary driven closure and firing systems and firing member that engages both jaws while firing |
US11090047B2 (en) | 2018-03-28 | 2021-08-17 | Cilag Gmbh International | Surgical instrument comprising an adaptive control system |
US11278280B2 (en) | 2018-03-28 | 2022-03-22 | Cilag Gmbh International | Surgical instrument comprising a jaw closure lockout |
US11129611B2 (en) | 2018-03-28 | 2021-09-28 | Cilag Gmbh International | Surgical staplers with arrangements for maintaining a firing member thereof in a locked configuration unless a compatible cartridge has been installed therein |
US11219453B2 (en) | 2018-03-28 | 2022-01-11 | Cilag Gmbh International | Surgical stapling devices with cartridge compatible closure and firing lockout arrangements |
US11589865B2 (en) | 2018-03-28 | 2023-02-28 | Cilag Gmbh International | Methods for controlling a powered surgical stapler that has separate rotary closure and firing systems |
BR112021000708A2 (pt) | 2018-07-16 | 2021-04-20 | Bbi Medical Innovations, Llc | medição de perfusão e oxigenação |
US11045192B2 (en) | 2018-08-20 | 2021-06-29 | Cilag Gmbh International | Fabricating techniques for surgical stapler anvils |
US11039834B2 (en) | 2018-08-20 | 2021-06-22 | Cilag Gmbh International | Surgical stapler anvils with staple directing protrusions and tissue stability features |
US11083458B2 (en) | 2018-08-20 | 2021-08-10 | Cilag Gmbh International | Powered surgical instruments with clutching arrangements to convert linear drive motions to rotary drive motions |
USD914878S1 (en) | 2018-08-20 | 2021-03-30 | Ethicon Llc | Surgical instrument anvil |
US11324501B2 (en) | 2018-08-20 | 2022-05-10 | Cilag Gmbh International | Surgical stapling devices with improved closure members |
US10779821B2 (en) | 2018-08-20 | 2020-09-22 | Ethicon Llc | Surgical stapler anvils with tissue stop features configured to avoid tissue pinch |
US11207065B2 (en) | 2018-08-20 | 2021-12-28 | Cilag Gmbh International | Method for fabricating surgical stapler anvils |
US10856870B2 (en) | 2018-08-20 | 2020-12-08 | Ethicon Llc | Switching arrangements for motor powered articulatable surgical instruments |
US11291440B2 (en) | 2018-08-20 | 2022-04-05 | Cilag Gmbh International | Method for operating a powered articulatable surgical instrument |
US11253256B2 (en) | 2018-08-20 | 2022-02-22 | Cilag Gmbh International | Articulatable motor powered surgical instruments with dedicated articulation motor arrangements |
US10912559B2 (en) | 2018-08-20 | 2021-02-09 | Ethicon Llc | Reinforced deformable anvil tip for surgical stapler anvil |
US10842492B2 (en) | 2018-08-20 | 2020-11-24 | Ethicon Llc | Powered articulatable surgical instruments with clutching and locking arrangements for linking an articulation drive system to a firing drive system |
CN113167729A (zh) * | 2018-11-21 | 2021-07-23 | 阿西耶斯医疗有限责任公司 | 医疗装置检测系统和方法 |
US11751872B2 (en) | 2019-02-19 | 2023-09-12 | Cilag Gmbh International | Insertable deactivator element for surgical stapler lockouts |
US11331100B2 (en) | 2019-02-19 | 2022-05-17 | Cilag Gmbh International | Staple cartridge retainer system with authentication keys |
US11317915B2 (en) | 2019-02-19 | 2022-05-03 | Cilag Gmbh International | Universal cartridge based key feature that unlocks multiple lockout arrangements in different surgical staplers |
US11369377B2 (en) | 2019-02-19 | 2022-06-28 | Cilag Gmbh International | Surgical stapling assembly with cartridge based retainer configured to unlock a firing lockout |
US11357503B2 (en) | 2019-02-19 | 2022-06-14 | Cilag Gmbh International | Staple cartridge retainers with frangible retention features and methods of using same |
US11696761B2 (en) | 2019-03-25 | 2023-07-11 | Cilag Gmbh International | Firing drive arrangements for surgical systems |
US11147551B2 (en) | 2019-03-25 | 2021-10-19 | Cilag Gmbh International | Firing drive arrangements for surgical systems |
US11172929B2 (en) | 2019-03-25 | 2021-11-16 | Cilag Gmbh International | Articulation drive arrangements for surgical systems |
US11147553B2 (en) | 2019-03-25 | 2021-10-19 | Cilag Gmbh International | Firing drive arrangements for surgical systems |
US11452528B2 (en) | 2019-04-30 | 2022-09-27 | Cilag Gmbh International | Articulation actuators for a surgical instrument |
US11903581B2 (en) | 2019-04-30 | 2024-02-20 | Cilag Gmbh International | Methods for stapling tissue using a surgical instrument |
US11432816B2 (en) | 2019-04-30 | 2022-09-06 | Cilag Gmbh International | Articulation pin for a surgical instrument |
US11648009B2 (en) | 2019-04-30 | 2023-05-16 | Cilag Gmbh International | Rotatable jaw tip for a surgical instrument |
US11471157B2 (en) | 2019-04-30 | 2022-10-18 | Cilag Gmbh International | Articulation control mapping for a surgical instrument |
US11253254B2 (en) | 2019-04-30 | 2022-02-22 | Cilag Gmbh International | Shaft rotation actuator on a surgical instrument |
US11426251B2 (en) | 2019-04-30 | 2022-08-30 | Cilag Gmbh International | Articulation directional lights on a surgical instrument |
USD964564S1 (en) | 2019-06-25 | 2022-09-20 | Cilag Gmbh International | Surgical staple cartridge retainer with a closure system authentication key |
USD950728S1 (en) | 2019-06-25 | 2022-05-03 | Cilag Gmbh International | Surgical staple cartridge |
USD952144S1 (en) | 2019-06-25 | 2022-05-17 | Cilag Gmbh International | Surgical staple cartridge retainer with firing system authentication key |
US11464601B2 (en) | 2019-06-28 | 2022-10-11 | Cilag Gmbh International | Surgical instrument comprising an RFID system for tracking a movable component |
US11553971B2 (en) | 2019-06-28 | 2023-01-17 | Cilag Gmbh International | Surgical RFID assemblies for display and communication |
US11638587B2 (en) | 2019-06-28 | 2023-05-02 | Cilag Gmbh International | RFID identification systems for surgical instruments |
US11298132B2 (en) | 2019-06-28 | 2022-04-12 | Cilag GmbH Inlernational | Staple cartridge including a honeycomb extension |
US11051807B2 (en) | 2019-06-28 | 2021-07-06 | Cilag Gmbh International | Packaging assembly including a particulate trap |
US11376098B2 (en) | 2019-06-28 | 2022-07-05 | Cilag Gmbh International | Surgical instrument system comprising an RFID system |
US11350938B2 (en) | 2019-06-28 | 2022-06-07 | Cilag Gmbh International | Surgical instrument comprising an aligned rfid sensor |
US11291451B2 (en) | 2019-06-28 | 2022-04-05 | Cilag Gmbh International | Surgical instrument with battery compatibility verification functionality |
US11523822B2 (en) | 2019-06-28 | 2022-12-13 | Cilag Gmbh International | Battery pack including a circuit interrupter |
US11684434B2 (en) | 2019-06-28 | 2023-06-27 | Cilag Gmbh International | Surgical RFID assemblies for instrument operational setting control |
US11298127B2 (en) | 2019-06-28 | 2022-04-12 | Cilag GmbH Interational | Surgical stapling system having a lockout mechanism for an incompatible cartridge |
US11627959B2 (en) | 2019-06-28 | 2023-04-18 | Cilag Gmbh International | Surgical instruments including manual and powered system lockouts |
US11246678B2 (en) | 2019-06-28 | 2022-02-15 | Cilag Gmbh International | Surgical stapling system having a frangible RFID tag |
US11219455B2 (en) | 2019-06-28 | 2022-01-11 | Cilag Gmbh International | Surgical instrument including a lockout key |
US11399837B2 (en) | 2019-06-28 | 2022-08-02 | Cilag Gmbh International | Mechanisms for motor control adjustments of a motorized surgical instrument |
US11660163B2 (en) | 2019-06-28 | 2023-05-30 | Cilag Gmbh International | Surgical system with RFID tags for updating motor assembly parameters |
US11426167B2 (en) | 2019-06-28 | 2022-08-30 | Cilag Gmbh International | Mechanisms for proper anvil attachment surgical stapling head assembly |
US11259803B2 (en) | 2019-06-28 | 2022-03-01 | Cilag Gmbh International | Surgical stapling system having an information encryption protocol |
US11224497B2 (en) | 2019-06-28 | 2022-01-18 | Cilag Gmbh International | Surgical systems with multiple RFID tags |
US11771419B2 (en) | 2019-06-28 | 2023-10-03 | Cilag Gmbh International | Packaging for a replaceable component of a surgical stapling system |
US11478241B2 (en) | 2019-06-28 | 2022-10-25 | Cilag Gmbh International | Staple cartridge including projections |
US11497492B2 (en) | 2019-06-28 | 2022-11-15 | Cilag Gmbh International | Surgical instrument including an articulation lock |
US11877833B2 (en) | 2019-07-26 | 2024-01-23 | Covidien Lp | Systems and methods for monitoring blood pressure with a powered linear drive |
US11304696B2 (en) | 2019-12-19 | 2022-04-19 | Cilag Gmbh International | Surgical instrument comprising a powered articulation system |
US11446029B2 (en) | 2019-12-19 | 2022-09-20 | Cilag Gmbh International | Staple cartridge comprising projections extending from a curved deck surface |
US11291447B2 (en) | 2019-12-19 | 2022-04-05 | Cilag Gmbh International | Stapling instrument comprising independent jaw closing and staple firing systems |
US11559304B2 (en) | 2019-12-19 | 2023-01-24 | Cilag Gmbh International | Surgical instrument comprising a rapid closure mechanism |
US11911032B2 (en) | 2019-12-19 | 2024-02-27 | Cilag Gmbh International | Staple cartridge comprising a seating cam |
US11701111B2 (en) | 2019-12-19 | 2023-07-18 | Cilag Gmbh International | Method for operating a surgical stapling instrument |
US11504122B2 (en) | 2019-12-19 | 2022-11-22 | Cilag Gmbh International | Surgical instrument comprising a nested firing member |
US11529139B2 (en) | 2019-12-19 | 2022-12-20 | Cilag Gmbh International | Motor driven surgical instrument |
US11576672B2 (en) | 2019-12-19 | 2023-02-14 | Cilag Gmbh International | Surgical instrument comprising a closure system including a closure member and an opening member driven by a drive screw |
US11607219B2 (en) | 2019-12-19 | 2023-03-21 | Cilag Gmbh International | Staple cartridge comprising a detachable tissue cutting knife |
US11844520B2 (en) | 2019-12-19 | 2023-12-19 | Cilag Gmbh International | Staple cartridge comprising driver retention members |
US11529137B2 (en) | 2019-12-19 | 2022-12-20 | Cilag Gmbh International | Staple cartridge comprising driver retention members |
US11234698B2 (en) | 2019-12-19 | 2022-02-01 | Cilag Gmbh International | Stapling system comprising a clamp lockout and a firing lockout |
US11464512B2 (en) | 2019-12-19 | 2022-10-11 | Cilag Gmbh International | Staple cartridge comprising a curved deck surface |
US11931033B2 (en) | 2019-12-19 | 2024-03-19 | Cilag Gmbh International | Staple cartridge comprising a latch lockout |
US20210204951A1 (en) * | 2020-01-08 | 2021-07-08 | Covidien Lp | Surgical apparatus |
JP2021132729A (ja) * | 2020-02-25 | 2021-09-13 | 株式会社壮健 | 生体情報検出器 |
USD976401S1 (en) | 2020-06-02 | 2023-01-24 | Cilag Gmbh International | Staple cartridge |
USD975851S1 (en) | 2020-06-02 | 2023-01-17 | Cilag Gmbh International | Staple cartridge |
USD975850S1 (en) | 2020-06-02 | 2023-01-17 | Cilag Gmbh International | Staple cartridge |
USD974560S1 (en) | 2020-06-02 | 2023-01-03 | Cilag Gmbh International | Staple cartridge |
USD975278S1 (en) | 2020-06-02 | 2023-01-10 | Cilag Gmbh International | Staple cartridge |
USD967421S1 (en) | 2020-06-02 | 2022-10-18 | Cilag Gmbh International | Staple cartridge |
USD966512S1 (en) | 2020-06-02 | 2022-10-11 | Cilag Gmbh International | Staple cartridge |
CN111657875B (zh) * | 2020-07-09 | 2021-01-29 | 深圳市则成电子股份有限公司 | 一种血氧测试方法、装置及其存储介质 |
US20220031320A1 (en) | 2020-07-28 | 2022-02-03 | Cilag Gmbh International | Surgical instruments with flexible firing member actuator constraint arrangements |
US11660093B2 (en) * | 2020-09-16 | 2023-05-30 | Cilag Gmbh International | Method of applying buttress to end effector of surgical stapler |
US11452523B2 (en) | 2020-09-16 | 2022-09-27 | Cilag Gmbh International | Apparatus and method to apply buttresses separately to jaws of end effector of surgical stapler |
US11419605B2 (en) | 2020-09-16 | 2022-08-23 | Cilag Gmbh International | Apparatus and method to close end effector of surgical stapler onto buttress |
US11559306B2 (en) | 2020-09-16 | 2023-01-24 | Cilag Gmbh International | Apparatus and method to detect full seating of buttress applicator in end effector of surgical stapler |
US11564683B2 (en) | 2020-09-16 | 2023-01-31 | Cilag Gmbh International | Apparatus and method to apply buttress to end effector of surgical stapler via driven member |
US11413040B2 (en) | 2020-09-16 | 2022-08-16 | Cilag Gmbh International | Apparatus and method to apply buttress to end effector of surgical stapler with authentication |
US11766261B2 (en) | 2020-09-16 | 2023-09-26 | Cilag Gmbh International | Apparatus and method to apply buttress to end effector of surgical stapler via fixed base |
US11844518B2 (en) | 2020-10-29 | 2023-12-19 | Cilag Gmbh International | Method for operating a surgical instrument |
US11717289B2 (en) | 2020-10-29 | 2023-08-08 | Cilag Gmbh International | Surgical instrument comprising an indicator which indicates that an articulation drive is actuatable |
US11931025B2 (en) | 2020-10-29 | 2024-03-19 | Cilag Gmbh International | Surgical instrument comprising a releasable closure drive lock |
US11452526B2 (en) | 2020-10-29 | 2022-09-27 | Cilag Gmbh International | Surgical instrument comprising a staged voltage regulation start-up system |
US11779330B2 (en) | 2020-10-29 | 2023-10-10 | Cilag Gmbh International | Surgical instrument comprising a jaw alignment system |
US11517390B2 (en) | 2020-10-29 | 2022-12-06 | Cilag Gmbh International | Surgical instrument comprising a limited travel switch |
USD980425S1 (en) | 2020-10-29 | 2023-03-07 | Cilag Gmbh International | Surgical instrument assembly |
US11896217B2 (en) | 2020-10-29 | 2024-02-13 | Cilag Gmbh International | Surgical instrument comprising an articulation lock |
USD1013170S1 (en) | 2020-10-29 | 2024-01-30 | Cilag Gmbh International | Surgical instrument assembly |
US11617577B2 (en) | 2020-10-29 | 2023-04-04 | Cilag Gmbh International | Surgical instrument comprising a sensor configured to sense whether an articulation drive of the surgical instrument is actuatable |
US11534259B2 (en) | 2020-10-29 | 2022-12-27 | Cilag Gmbh International | Surgical instrument comprising an articulation indicator |
US11653920B2 (en) | 2020-12-02 | 2023-05-23 | Cilag Gmbh International | Powered surgical instruments with communication interfaces through sterile barrier |
US11627960B2 (en) | 2020-12-02 | 2023-04-18 | Cilag Gmbh International | Powered surgical instruments with smart reload with separately attachable exteriorly mounted wiring connections |
US11653915B2 (en) | 2020-12-02 | 2023-05-23 | Cilag Gmbh International | Surgical instruments with sled location detection and adjustment features |
US11737751B2 (en) | 2020-12-02 | 2023-08-29 | Cilag Gmbh International | Devices and methods of managing energy dissipated within sterile barriers of surgical instrument housings |
US11944296B2 (en) | 2020-12-02 | 2024-04-02 | Cilag Gmbh International | Powered surgical instruments with external connectors |
US11678882B2 (en) | 2020-12-02 | 2023-06-20 | Cilag Gmbh International | Surgical instruments with interactive features to remedy incidental sled movements |
US11890010B2 (en) | 2020-12-02 | 2024-02-06 | Cllag GmbH International | Dual-sided reinforced reload for surgical instruments |
US11849943B2 (en) | 2020-12-02 | 2023-12-26 | Cilag Gmbh International | Surgical instrument with cartridge release mechanisms |
US11744581B2 (en) | 2020-12-02 | 2023-09-05 | Cilag Gmbh International | Powered surgical instruments with multi-phase tissue treatment |
US11751869B2 (en) | 2021-02-26 | 2023-09-12 | Cilag Gmbh International | Monitoring of multiple sensors over time to detect moving characteristics of tissue |
US11701113B2 (en) | 2021-02-26 | 2023-07-18 | Cilag Gmbh International | Stapling instrument comprising a separate power antenna and a data transfer antenna |
US11749877B2 (en) | 2021-02-26 | 2023-09-05 | Cilag Gmbh International | Stapling instrument comprising a signal antenna |
US11723657B2 (en) | 2021-02-26 | 2023-08-15 | Cilag Gmbh International | Adjustable communication based on available bandwidth and power capacity |
US11925349B2 (en) | 2021-02-26 | 2024-03-12 | Cilag Gmbh International | Adjustment to transfer parameters to improve available power |
US11696757B2 (en) | 2021-02-26 | 2023-07-11 | Cilag Gmbh International | Monitoring of internal systems to detect and track cartridge motion status |
US11950777B2 (en) | 2021-02-26 | 2024-04-09 | Cilag Gmbh International | Staple cartridge comprising an information access control system |
US11812964B2 (en) | 2021-02-26 | 2023-11-14 | Cilag Gmbh International | Staple cartridge comprising a power management circuit |
US11950779B2 (en) | 2021-02-26 | 2024-04-09 | Cilag Gmbh International | Method of powering and communicating with a staple cartridge |
US11730473B2 (en) | 2021-02-26 | 2023-08-22 | Cilag Gmbh International | Monitoring of manufacturing life-cycle |
US11793514B2 (en) | 2021-02-26 | 2023-10-24 | Cilag Gmbh International | Staple cartridge comprising sensor array which may be embedded in cartridge body |
US11744583B2 (en) | 2021-02-26 | 2023-09-05 | Cilag Gmbh International | Distal communication array to tune frequency of RF systems |
US11759202B2 (en) | 2021-03-22 | 2023-09-19 | Cilag Gmbh International | Staple cartridge comprising an implantable layer |
US11826042B2 (en) | 2021-03-22 | 2023-11-28 | Cilag Gmbh International | Surgical instrument comprising a firing drive including a selectable leverage mechanism |
US11717291B2 (en) | 2021-03-22 | 2023-08-08 | Cilag Gmbh International | Staple cartridge comprising staples configured to apply different tissue compression |
US11737749B2 (en) | 2021-03-22 | 2023-08-29 | Cilag Gmbh International | Surgical stapling instrument comprising a retraction system |
US11826012B2 (en) | 2021-03-22 | 2023-11-28 | Cilag Gmbh International | Stapling instrument comprising a pulsed motor-driven firing rack |
US11806011B2 (en) | 2021-03-22 | 2023-11-07 | Cilag Gmbh International | Stapling instrument comprising tissue compression systems |
US11723658B2 (en) | 2021-03-22 | 2023-08-15 | Cilag Gmbh International | Staple cartridge comprising a firing lockout |
US11793516B2 (en) | 2021-03-24 | 2023-10-24 | Cilag Gmbh International | Surgical staple cartridge comprising longitudinal support beam |
US11849944B2 (en) | 2021-03-24 | 2023-12-26 | Cilag Gmbh International | Drivers for fastener cartridge assemblies having rotary drive screws |
US11786243B2 (en) | 2021-03-24 | 2023-10-17 | Cilag Gmbh International | Firing members having flexible portions for adapting to a load during a surgical firing stroke |
US11944336B2 (en) | 2021-03-24 | 2024-04-02 | Cilag Gmbh International | Joint arrangements for multi-planar alignment and support of operational drive shafts in articulatable surgical instruments |
US11896219B2 (en) | 2021-03-24 | 2024-02-13 | Cilag Gmbh International | Mating features between drivers and underside of a cartridge deck |
US11896218B2 (en) | 2021-03-24 | 2024-02-13 | Cilag Gmbh International | Method of using a powered stapling device |
US11903582B2 (en) | 2021-03-24 | 2024-02-20 | Cilag Gmbh International | Leveraging surfaces for cartridge installation |
US11832816B2 (en) | 2021-03-24 | 2023-12-05 | Cilag Gmbh International | Surgical stapling assembly comprising nonplanar staples and planar staples |
US11849945B2 (en) | 2021-03-24 | 2023-12-26 | Cilag Gmbh International | Rotary-driven surgical stapling assembly comprising eccentrically driven firing member |
US11744603B2 (en) | 2021-03-24 | 2023-09-05 | Cilag Gmbh International | Multi-axis pivot joints for surgical instruments and methods for manufacturing same |
US11857183B2 (en) | 2021-03-24 | 2024-01-02 | Cilag Gmbh International | Stapling assembly components having metal substrates and plastic bodies |
US11786239B2 (en) | 2021-03-24 | 2023-10-17 | Cilag Gmbh International | Surgical instrument articulation joint arrangements comprising multiple moving linkage features |
RU2757251C1 (ru) * | 2021-04-05 | 2021-10-12 | федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Западный государственный медицинский университет им. И.И. Мечникова" Министерства здравоохранения Российской Федерации | Способ эндовидеохирургического определения жизнеспособности кишки, ущемленной в паховой грыже |
US11826047B2 (en) | 2021-05-28 | 2023-11-28 | Cilag Gmbh International | Stapling instrument comprising jaw mounts |
ES2929671A1 (es) * | 2021-05-31 | 2022-11-30 | Univ Madrid Carlos Iii | Dispositivo de monitorizacion del estado de perfusion de colgajos de piel |
WO2022266137A1 (en) * | 2021-06-14 | 2022-12-22 | The Regents Of The University Of California | Probe for identification of ocular tissues during surgery |
US11877745B2 (en) | 2021-10-18 | 2024-01-23 | Cilag Gmbh International | Surgical stapling assembly having longitudinally-repeating staple leg clusters |
US11957337B2 (en) | 2021-10-18 | 2024-04-16 | Cilag Gmbh International | Surgical stapling assembly with offset ramped drive surfaces |
US11937816B2 (en) | 2021-10-28 | 2024-03-26 | Cilag Gmbh International | Electrical lead arrangements for surgical instruments |
US11857294B2 (en) * | 2021-11-04 | 2024-01-02 | The Texas A&M University System | Medical devices for measuring tissue properties and methods of use |
WO2024003699A1 (en) * | 2022-06-29 | 2024-01-04 | Covidien Lp | Real-time stapling tissue perfusion assessment |
FR3140285A1 (fr) * | 2022-09-29 | 2024-04-05 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Procédé et de détermination de l'état de fonctionnement d'un implant lumineux |
Family Cites Families (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4515165A (en) | 1980-02-04 | 1985-05-07 | Energy Conversion Devices, Inc. | Apparatus and method for detecting tumors |
JPS59500896A (ja) * | 1982-03-30 | 1984-05-24 | アメリカ合衆国 | 光ファイバーを用いた酸素分圧測定装置 |
US4476870A (en) * | 1982-03-30 | 1984-10-16 | The United States Of America As Represented By The Department Of Health And Human Services | Fiber optic PO.sbsb.2 probe |
DE3313047A1 (de) * | 1983-04-12 | 1984-10-18 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Anordnung zur messung von diffundierenden partikeln |
US4895156A (en) * | 1986-07-02 | 1990-01-23 | Schulze John E | Sensor system using fluorometric decay measurements |
US4947850A (en) | 1988-03-11 | 1990-08-14 | Trustees Of The University Of Pennsylvania | Method and apparatus for imaging an internal body portion of a host animal |
US5071417A (en) * | 1990-06-15 | 1991-12-10 | Rare Earth Medical Lasers, Inc. | Laser fusion of biological materials |
US5186173A (en) * | 1990-08-14 | 1993-02-16 | Drexel University | Method for in vivo measurement of oxygen concentration levels |
US6362175B1 (en) | 1991-09-20 | 2002-03-26 | The Trustees Of The University Of Pennsylvania | Porphyrin compounds for imaging tissue oxygen |
US5772597A (en) | 1992-09-14 | 1998-06-30 | Sextant Medical Corporation | Surgical tool end effector |
US5593899A (en) * | 1993-02-25 | 1997-01-14 | Trustees Of The University Of Pennsylvania | Device and method for measuring tissue oxygenation through the skin using oxygen dependent quenching of phosphorescence |
US5987346A (en) | 1993-02-26 | 1999-11-16 | Benaron; David A. | Device and method for classification of tissue |
US5837865A (en) | 1993-10-15 | 1998-11-17 | Trustees Of The University Of Pennsylvania | Phosphorescent dendritic macromolecular compounds for imaging tissue oxygen |
US5515864A (en) * | 1994-04-21 | 1996-05-14 | Zuckerman; Ralph | Method and apparatus for the in vivo measurement of oxygen concentration levels by the indirect determination of fluoescence lifetime |
US5833603A (en) | 1996-03-13 | 1998-11-10 | Lipomatrix, Inc. | Implantable biosensing transponder |
US6274086B1 (en) | 1996-12-16 | 2001-08-14 | The Trustees Of The University Of Pennsylvania | Apparatus for non-invasive imaging oxygen distribution in multi-dimensions |
US5860917A (en) | 1997-01-15 | 1999-01-19 | Chiron Corporation | Method and apparatus for predicting therapeutic outcomes |
US6165741A (en) | 1997-05-30 | 2000-12-26 | The Trustees Of The University Of Pennsylvania | Method for rapid detection of bacterial growth in cultures |
GB9814506D0 (en) | 1998-07-03 | 1998-09-02 | Stanley Christopher J | Optical sensor for insitu measurement of analytes |
DK2325622T3 (da) * | 1998-08-26 | 2014-05-26 | Senseonics Inc | Optisk-baseret føleindretning |
DK1867275T3 (da) | 1998-09-30 | 2011-04-04 | Sicel Technologies Inc | Systemer med implanterbare aooarater til dynamisk overvågning af tumorer |
US6248117B1 (en) * | 1999-04-16 | 2001-06-19 | Vital Access Corp | Anastomosis apparatus for use in intraluminally directed vascular anastomosis |
US6623494B1 (en) * | 1999-04-16 | 2003-09-23 | Integrated Vascular Interventional Technologies, L.C. (Ivit, Lc) | Methods and systems for intraluminally directed vascular anastomosis |
US6701168B1 (en) | 1999-10-14 | 2004-03-02 | Trustees Of The University Of Pennsylvania | Apparatus for measuring an oxygen concentration gradient and method of use thereof |
US6652452B1 (en) | 1999-10-25 | 2003-11-25 | Advanced Medical Electronics Corporation | Infrared endoscope with sensor array at the distal tip |
US6869430B2 (en) | 2000-03-31 | 2005-03-22 | Rita Medical Systems, Inc. | Tissue biopsy and treatment apparatus and method |
US6975898B2 (en) | 2000-06-19 | 2005-12-13 | University Of Washington | Medical imaging, diagnosis, and therapy using a scanning single optical fiber system |
EP1301118B1 (en) | 2000-07-14 | 2006-09-06 | Xillix Technologies Corp. | Compact fluorescence endoscopy video system |
DE10059070C1 (de) | 2000-11-28 | 2002-02-14 | Pulsion Medical Sys Ag | Vorrichtung zur Bestimmung von Gewebeperfusion und intraoperative Verwendung |
US20020143294A1 (en) * | 2001-02-14 | 2002-10-03 | Duchon Douglas J. | Catheter fluid control system |
US6707168B1 (en) | 2001-05-04 | 2004-03-16 | Amkor Technology, Inc. | Shielded semiconductor package with single-sided substrate and method for making the same |
US6664111B2 (en) | 2001-08-22 | 2003-12-16 | 3M Innovative Properties Company | Fluorescence based oxygen sensor systems |
US20030045798A1 (en) * | 2001-09-04 | 2003-03-06 | Richard Hular | Multisensor probe for tissue identification |
US20060241496A1 (en) | 2002-01-15 | 2006-10-26 | Xillix Technologies Corp. | Filter for use with imaging endoscopes |
WO2003090630A2 (en) | 2002-04-25 | 2003-11-06 | Tyco Healthcare Group, Lp | Surgical instruments including micro-electromechanical systems (mems) |
AU2003249807A1 (en) | 2002-07-17 | 2004-02-02 | Novadaq Technologies Inc. | Combined photocoagulation and photodynamic therapy |
US7532325B2 (en) * | 2003-09-23 | 2009-05-12 | Research Foundation Of The City University Of New York | Method and apparatus for the separation of fluoroscence and elastic scattering produced by broadband illumination using polarization discrimination techniques |
EP1701654B1 (en) * | 2003-12-18 | 2016-11-09 | Metronom Health, Inc. | Implantable biosensor and methods of use thereof |
US8948836B2 (en) * | 2003-12-26 | 2015-02-03 | Medtronic Minimed, Inc. | Implantable apparatus for sensing multiple parameters |
US7899508B2 (en) * | 2004-03-11 | 2011-03-01 | Board Of Regents, The University Of Texas System | Intracorporeal impedance and leak monitoring device |
US8082015B2 (en) * | 2004-04-13 | 2011-12-20 | The Trustees Of The University Of Pennsylvania | Optical measurement of tissue blood flow, hemodynamics and oxygenation |
WO2006026396A2 (en) * | 2004-08-26 | 2006-03-09 | Oxygen Enterprises, Ltd. | Imaging of oxygen by phosphorescence quenching |
US20080310583A1 (en) | 2005-01-10 | 2008-12-18 | Koninklijke Philips Electronics N.V. | Cardiopulmonary Screening with Feedback From Analysis to Acquisition |
DE102005024578A1 (de) | 2005-05-25 | 2006-11-30 | Raumedic Ag | Sonde zur Messung des Sauerstoffgehaltes in biologischem Gewebe sowie Katheter mit einer derartigen Sonde |
US7530948B2 (en) | 2005-02-28 | 2009-05-12 | University Of Washington | Tethered capsule endoscope for Barrett's Esophagus screening |
WO2006113394A2 (en) * | 2005-04-15 | 2006-10-26 | Surgisense Corporation | Surgical instruments with sensors for detecting tissue properties, and systems using such instruments |
US20060239921A1 (en) | 2005-04-26 | 2006-10-26 | Novadaq Technologies Inc. | Real time vascular imaging during solid organ transplant |
WO2006116634A2 (en) | 2005-04-26 | 2006-11-02 | Novadaq Technologies, Inc. | Method and apparatus for vasculature visualization with applications in neurosurgery and neurology |
JP5058977B2 (ja) | 2005-04-29 | 2012-10-24 | ノバダック テクノロジーズ インコーポレイテッド | 脈絡膜及び網膜を画像化及び治療するシステム |
US10231624B2 (en) | 2005-08-10 | 2019-03-19 | Nov Adaq Technologies Ulc | Intra-operative head and neck nerve mapping |
JP4734074B2 (ja) * | 2005-09-30 | 2011-07-27 | オリンパスメディカルシステムズ株式会社 | 内視鏡装置 |
US7420151B2 (en) | 2005-10-17 | 2008-09-02 | Novadaq Technologies Inc. | Device for short wavelength visible reflectance endoscopy using broadband illumination |
US7486977B2 (en) * | 2005-10-27 | 2009-02-03 | Smiths Medical Pm, Inc. | Single use pulse oximeter |
DE602006005843D1 (de) | 2005-11-23 | 2009-04-30 | Koninkl Philips Electronics Nv | Vorrichtung zur abbildung des inneren eines trüben mediums |
EP1973503B1 (en) * | 2006-01-04 | 2013-09-25 | The Trustees of the University of Pennsylvania | Oxygen sensor for internal monitoring of tissue oxygen in vivo |
US20110105869A1 (en) * | 2006-01-04 | 2011-05-05 | The Trustees Of The University Of Pennsylvania | Sensor for Internal Monitoring of Tissue O2 and/or pH/CO2 In Vivo |
US7575890B2 (en) | 2006-01-18 | 2009-08-18 | Oxygen Enterprises, Ltd. | Method for rapid detection and evaluation of cultured cell growth |
US20090303317A1 (en) | 2006-02-07 | 2009-12-10 | Novadaq Technologies Inc. | Near infrared imaging |
WO2007110867A2 (en) * | 2006-03-28 | 2007-10-04 | Glusense Ltd. | Implantable sensor |
US20100081895A1 (en) | 2006-06-21 | 2010-04-01 | Jason Matthew Zand | Wireless medical telemetry system and methods using radio frequency energized biosensors |
US20080051646A1 (en) * | 2006-07-24 | 2008-02-28 | Papkovsky Dmitri B | Probe for cellular oxygen |
JP5228161B2 (ja) | 2007-03-09 | 2013-07-03 | 富士フイルム株式会社 | 内視鏡の湾曲装置 |
JP2009063637A (ja) | 2007-09-04 | 2009-03-26 | Fujifilm Corp | 光走査プローブおよび光走査プローブ装置並びに光走査プローブの制御方法 |
US8118206B2 (en) * | 2008-03-15 | 2012-02-21 | Surgisense Corporation | Sensing adjunct for surgical staplers |
US8010210B2 (en) * | 2008-04-30 | 2011-08-30 | Medizinische Hochschule Hannover | Apparatus and system for insertion of an implant |
US8694266B2 (en) * | 2008-06-05 | 2014-04-08 | The Regents Of The University Of Michigan | Multimodal spectroscopic systems and methods for classifying biological tissue |
JP2011529577A (ja) | 2008-07-28 | 2011-12-08 | センサーズ・フォー・メデセン・アンド・サイエンス・インコーポレーテッド | 検体濃度の光学測定システムおよび方法 |
US8332007B2 (en) * | 2009-01-12 | 2012-12-11 | The Board Of Trustees Of The University Of Illinois | Quantitative three-dimensional mapping of oxygen tension |
US9155471B2 (en) * | 2009-05-27 | 2015-10-13 | Lumicell, Inc'. | Methods and systems for spatially identifying abnormal cells |
EP2456361B1 (en) * | 2009-07-23 | 2019-12-11 | Abbott Diabetes Care, Inc. | Continuous analyte measurement system |
US9198683B2 (en) * | 2009-09-30 | 2015-12-01 | Aegis Medical Innovations, Inc. | Tissue capture and occlusion systems and methods |
US8694069B1 (en) * | 2009-12-21 | 2014-04-08 | Kosense, LLC | Fiber-optic probe with embedded peripheral sensors for in-situ continuous monitoring |
JP5452300B2 (ja) * | 2010-03-19 | 2014-03-26 | 富士フイルム株式会社 | 電子内視鏡システム、電子内視鏡用のプロセッサ装置、電子内視鏡システムの作動方法、病理観察装置および病理顕微鏡装置 |
JP5616303B2 (ja) * | 2010-08-24 | 2014-10-29 | 富士フイルム株式会社 | 電子内視鏡システム及び電子内視鏡システムの作動方法 |
US20120053433A1 (en) * | 2010-08-24 | 2012-03-01 | Nellcor Puritan Bennett Llc | SYSTEM AND METHOD TO DETERMINE SpO2 VARIABILITY AND ADDITIONAL PHYSIOLOGICAL PARAMETERS TO DETECT PATIENT STATUS |
JP5231511B2 (ja) * | 2010-11-09 | 2013-07-10 | 富士フイルム株式会社 | 内視鏡診断装置 |
US20120153188A1 (en) * | 2010-12-16 | 2012-06-21 | University Of Miami | Microscope accessory and microplate apparatus for measuring phosphorescence and cellular oxygen consumption |
US9220415B2 (en) | 2011-10-25 | 2015-12-29 | Andreas Mandelis | Systems and methods for frequency-domain photoacoustic phased array imaging |
US9556213B2 (en) | 2012-02-27 | 2017-01-31 | Sergei A. Vinogradov | Phosphorescent meso-unsubstituted metallo-tetrabenzoporphyrin probe molecules for measuring oxygen and imaging methods |
WO2014153428A1 (en) | 2013-03-19 | 2014-09-25 | Surgisense Corporation | Apparatus, systems and methods for determining tissue oxygenation |
-
2014
- 2014-03-19 WO PCT/US2014/031267 patent/WO2014153428A1/en active Application Filing
- 2014-03-19 EP EP22159020.1A patent/EP4079242A1/en active Pending
- 2014-03-19 US US14/220,034 patent/US9420967B2/en active Active
- 2014-03-19 JP JP2016505500A patent/JP6554089B2/ja active Active
- 2014-03-19 EP EP14767896.5A patent/EP2976033A4/en not_active Ceased
-
2016
- 2016-07-06 US US15/203,634 patent/US20160310055A1/en not_active Abandoned
-
2018
- 2018-10-12 US US16/159,385 patent/US20190282145A1/en not_active Abandoned
-
2019
- 2019-07-05 JP JP2019125937A patent/JP6781807B2/ja active Active
-
2020
- 2020-10-16 JP JP2020174790A patent/JP7164577B2/ja active Active
-
2021
- 2021-07-14 US US17/375,735 patent/US20210338121A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4079242A1 (en) | 2022-10-26 |
JP2019184617A (ja) | 2019-10-24 |
US9420967B2 (en) | 2016-08-23 |
JP7164577B2 (ja) | 2022-11-01 |
US20160310055A1 (en) | 2016-10-27 |
JP2021037299A (ja) | 2021-03-11 |
JP2016523576A (ja) | 2016-08-12 |
JP6554089B2 (ja) | 2019-07-31 |
US20210338121A1 (en) | 2021-11-04 |
WO2014153428A1 (en) | 2014-09-25 |
EP2976033A4 (en) | 2016-12-14 |
US20190282145A1 (en) | 2019-09-19 |
EP2976033A1 (en) | 2016-01-27 |
US20140288386A1 (en) | 2014-09-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6781807B2 (ja) | 組織酸素化の測定用の器具、システムおよびメソッド | |
EP3099223B1 (en) | Method and system for non-invasively monitoring biological or biochemical parameters of individual | |
US8395775B2 (en) | Fluorescent agent concentration measuring apparatus, dose control apparatus, administration system, fluorescent agent concentration measuring method, and dose control method | |
US8364222B2 (en) | Imaging apparatus and method | |
JP6608434B2 (ja) | 眼の層間の位置を検出するための方法及び装置 | |
US20090048502A1 (en) | Broadband illuminator for oximetry, hemoglobin, met-hemoglobin, carboxy-hemoglobin, and other blood component monitoring | |
US20040230132A1 (en) | Surgical drain with positioning and protective features | |
US20080188727A1 (en) | Broadband solid-state spectroscopy illuminator and method | |
US20030187427A1 (en) | Method and apparatus for in VIVO treatment of mammary ducts by light induced fluorescence | |
CN104144640B (zh) | 导管结构和用于定位身体器官中的组织并且同时提供治疗并评估所提供的治疗的方法 | |
WO2014020611A1 (en) | Method and system for non-invasively monitoring biological or biochemical parameters of individual | |
US20200015930A1 (en) | Method and device for enhanced transdermal visualization of medical devices | |
US20210268302A1 (en) | Treatment method | |
JP2021506436A (ja) | 膀胱充満を感知するための装置及び方法 | |
Katzir | Optical fibers in medicine | |
US20080125663A1 (en) | Pre-And Intra-Operative Imaging of Testicular Torsion | |
Garg et al. | Equipment planning | |
KR102032438B1 (ko) | 체내 부착 발광장치 | |
O'Hara et al. | Uptake of verteporfin by orthotopic xenograft pancreas models with different levels of aggression | |
Bogaards et al. | Fluorescence-guided resection of intracranial VX2 tumor in a preclinical model using 5-aminolevulinic acid (ALA): preliminary results | |
JP2022055167A (ja) | 医療用蛍光装置 | |
RU2252041C1 (ru) | Гемостатический дуоденальный зонд | |
RU2002118588A (ru) | Способ дифференциальной диагностики ринитов |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190705 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20191009 |
|
RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20191009 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20191030 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20200413 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200710 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200817 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20200916 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20201016 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6781807 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |