JP6773268B2 - 多能性幹細胞を所望の細胞型へ分化する方法 - Google Patents
多能性幹細胞を所望の細胞型へ分化する方法 Download PDFInfo
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- JP6773268B2 JP6773268B2 JP2017505381A JP2017505381A JP6773268B2 JP 6773268 B2 JP6773268 B2 JP 6773268B2 JP 2017505381 A JP2017505381 A JP 2017505381A JP 2017505381 A JP2017505381 A JP 2017505381A JP 6773268 B2 JP6773268 B2 JP 6773268B2
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020075056A JP6903355B2 (ja) | 2015-03-09 | 2020-04-20 | 多能性幹細胞を所望の細胞型へ分化する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015046318 | 2015-03-09 | ||
| JP2015046318 | 2015-03-09 | ||
| PCT/JP2016/057420 WO2016143826A1 (ja) | 2015-03-09 | 2016-03-09 | 多能性幹細胞を所望の細胞型へ分化する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020075056A Division JP6903355B2 (ja) | 2015-03-09 | 2020-04-20 | 多能性幹細胞を所望の細胞型へ分化する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2016143826A1 JPWO2016143826A1 (ja) | 2018-02-15 |
| JP6773268B2 true JP6773268B2 (ja) | 2020-10-21 |
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| JP2017505381A Active JP6773268B2 (ja) | 2015-03-09 | 2016-03-09 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2020075056A Active JP6903355B2 (ja) | 2015-03-09 | 2020-04-20 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2021099810A Active JP7403841B2 (ja) | 2015-03-09 | 2021-06-16 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2023063437A Pending JP2023085519A (ja) | 2015-03-09 | 2023-04-10 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2024210817A Pending JP2025032187A (ja) | 2015-03-09 | 2024-12-04 | 多能性幹細胞を所望の細胞型へ分化する方法 |
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| JP2020075056A Active JP6903355B2 (ja) | 2015-03-09 | 2020-04-20 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2021099810A Active JP7403841B2 (ja) | 2015-03-09 | 2021-06-16 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2023063437A Pending JP2023085519A (ja) | 2015-03-09 | 2023-04-10 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| JP2024210817A Pending JP2025032187A (ja) | 2015-03-09 | 2024-12-04 | 多能性幹細胞を所望の細胞型へ分化する方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US10836997B2 (OSRAM) |
| JP (5) | JP6773268B2 (OSRAM) |
| WO (1) | WO2016143826A1 (OSRAM) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP6773268B2 (ja) | 2015-03-09 | 2020-10-21 | 学校法人慶應義塾 | 多能性幹細胞を所望の細胞型へ分化する方法 |
| SG10201912931RA (en) * | 2015-08-31 | 2020-02-27 | I Peace Inc | Pluripotent stem cell manufacturing system, method for inducing stem cells, floating culture method for stem cells, floating culture vessel for stem cells, method for producing induced pluripotent stem cells, and method for producing particular somatic cells from animal cells |
| US11286454B2 (en) | 2015-08-31 | 2022-03-29 | I Peace, Inc. | Pluripotent stem cell manufacturing system and method for producing induced pluripotent stem cells |
| EP3369434A4 (en) * | 2015-10-30 | 2019-05-08 | MIURA, Norimasa | INHIBITORS FOR METHYLATION-ASSOCIATED ENZYMES HAT1 AND KAT8 |
| CN108779441A (zh) * | 2016-03-15 | 2018-11-09 | 学校法人庆应义塾 | 由多能干细胞制造心脏祖细胞和心肌细胞的制造方法 |
| EP3510146B1 (en) | 2016-09-12 | 2026-02-11 | President and Fellows of Harvard College | Transcription factors controlling differentiation of stem cells |
| GB201619876D0 (en) | 2016-11-24 | 2017-01-11 | Cambridge Entpr Ltd | Controllable transcription |
| CA3054120A1 (en) * | 2017-02-24 | 2018-08-30 | Koji Tanabe | Nerve cell production method by introduction of inducing factor rna |
| JP2018143239A (ja) * | 2017-03-01 | 2018-09-20 | エリクサジェン,エルエルシー. | 多能性幹細胞を所望の細胞型へ効率的に分化する方法 |
| US12031153B2 (en) | 2017-12-01 | 2024-07-09 | President And Fellows Of Harvard College | Methods and compositions for the production of oligodendrocyte progenitor cells |
| WO2019195675A1 (en) | 2018-04-06 | 2019-10-10 | President And Fellows Of Harvard College | Methods of identifying combinations of transcription factors |
| WO2020223674A2 (en) * | 2019-05-01 | 2020-11-05 | Board Of Regents Of The University Of Texas System | Methods and compositions for regulating adipogenesis |
| BR112021023618A2 (pt) * | 2019-05-27 | 2022-04-12 | Univ Muenster Westfaelische Wilhelms | Geração rápida e determinística de micróglia a partir de células tronco pluripotentes humanas |
| SG11202113095PA (en) | 2019-05-31 | 2021-12-30 | Harvard College | Sox9-induced oligodendrocyte progenitor cells |
| KR20220047623A (ko) * | 2019-08-19 | 2022-04-18 | 듀크 유니버시티 | 세포 유형 운명 특정화의 조절인자를 확인하기 위한 조성물 및 방법 |
| CA3156954A1 (en) * | 2019-11-25 | 2021-06-03 | Asgard Therapeutics Ab | Compositions for reprogramming cells into dendritic cells type 2 competent for antigen presentation, methods and uses thereof |
| MX2022011245A (es) | 2020-03-11 | 2023-01-11 | Bit Bio Ltd | Método de generación de células hepáticas. |
| CN113652402A (zh) * | 2020-05-12 | 2021-11-16 | 再康医药科技(上海)有限公司 | 一种诱导胶质细胞转分化为功能性神经元的方法及其应用 |
| CN112626023B (zh) * | 2021-01-12 | 2023-08-04 | 中国人民解放军海军军医大学 | 脊髓olig2+神经祖细胞诱导及自我更新培养体系、诱导方法及应用 |
| TW202309268A (zh) * | 2021-05-07 | 2023-03-01 | 安斯泰來再生醫藥協會 | 產生成熟肝細胞的方法 |
| WO2022239724A1 (en) | 2021-05-10 | 2022-11-17 | Okinawa Institute Of Science And Technology School Corporation | A modified rhabdovirus having a reduced toxicity |
| JP7268911B2 (ja) * | 2021-09-16 | 2023-05-08 | 株式会社ユニバーサルエンターテインメント | 遊技機 |
| JP7306745B2 (ja) * | 2021-09-16 | 2023-07-11 | 株式会社ユニバーサルエンターテインメント | 遊技機 |
| JP7306746B2 (ja) * | 2021-09-16 | 2023-07-11 | 株式会社ユニバーサルエンターテインメント | 遊技機 |
| WO2024091801A2 (en) * | 2022-10-13 | 2024-05-02 | President And Fellows Of Harvard College | Methods and compositions for inducing cell differentiation |
| WO2025254221A1 (ja) * | 2024-06-07 | 2025-12-11 | 国立大学法人九州大学 | 形質転換幹細胞、神経細胞、及び、形質転換幹細胞由来の神経細胞の作製方法 |
| WO2026023241A1 (ja) * | 2024-07-26 | 2026-01-29 | 株式会社リコー | 神経系細胞の製造方法及び神経系細胞誘導剤 |
| JP7755342B1 (ja) * | 2024-10-02 | 2025-10-16 | 株式会社Dioseve | 卵子様細胞を製造する方法、及び卵子様細胞 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7344857B2 (en) * | 1996-09-27 | 2008-03-18 | California Institute Of Technology | Neurogenin |
| EP1290141A4 (en) * | 2000-06-05 | 2005-01-05 | Burnham Inst | METHODS OF DIFFERENTIATION AND PROTECTION OF CELLS BY MODULATION OF P38 / MEF2 PATH |
| JP2004016109A (ja) * | 2002-06-17 | 2004-01-22 | Nagoya Industrial Science Research Inst | 軟骨細胞様細胞、及びその作製方法 |
| AU2003273332A1 (en) * | 2002-09-26 | 2004-04-19 | Children's Medical Center Corporation | Method of enhancing proliferation and/or hematopoietic differentiation of stem cells |
| JP4706208B2 (ja) * | 2004-08-27 | 2011-06-22 | 株式会社アイル | 造血幹細胞の製造方法 |
| EP2002037B1 (en) * | 2006-03-07 | 2015-09-16 | The Trustees of the University of Pennsylvania | Random rnai libraries, methods of generating same, and screening methods utilizing same |
| US20120231490A1 (en) * | 2009-10-28 | 2012-09-13 | Japan Health Sciences Foundation | Method Of Differentiation From Stem Cells To Hepatocytes |
| JP5968871B2 (ja) * | 2010-04-13 | 2016-08-10 | セルラー ダイナミクス インターナショナル, インコーポレイテッド | フォワードプログラミングによる肝細胞の産生 |
| WO2012109208A2 (en) * | 2011-02-08 | 2012-08-16 | Cellular Dynamics International, Inc. | Hematopoietic precursor cell production by programming |
| WO2013025963A2 (en) | 2011-08-17 | 2013-02-21 | President And Fellows Of Harvard College | Conversion of somatic cells into functional spinal motor neurons, and methods and uses thereof |
| US8497124B2 (en) * | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| US9260696B2 (en) * | 2012-04-24 | 2016-02-16 | Dan S. Kaufman | Method for developing natural killer cells from stem cells |
| JP5970245B2 (ja) | 2012-06-06 | 2016-08-17 | 公益財団法人ヒューマンサイエンス振興財団 | 幹細胞から肝細胞への分化誘導方法 |
| JP5987063B2 (ja) * | 2012-10-29 | 2016-09-06 | 学校法人 埼玉医科大学 | 分化多能性幹細胞の製造方法 |
| SG11201507275TA (en) * | 2013-03-13 | 2015-10-29 | Wisconsin Alumni Res Found | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
| US10519421B2 (en) | 2013-03-21 | 2019-12-31 | Kyoto University | Induction of motor neurons from pluripotent stem cells |
| JP6773268B2 (ja) | 2015-03-09 | 2020-10-21 | 学校法人慶應義塾 | 多能性幹細胞を所望の細胞型へ分化する方法 |
-
2016
- 2016-03-09 JP JP2017505381A patent/JP6773268B2/ja active Active
- 2016-03-09 US US15/555,559 patent/US10836997B2/en active Active
- 2016-03-09 WO PCT/JP2016/057420 patent/WO2016143826A1/ja not_active Ceased
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2020
- 2020-04-20 JP JP2020075056A patent/JP6903355B2/ja active Active
- 2020-10-08 US US17/065,541 patent/US11891621B2/en active Active
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2021
- 2021-06-16 JP JP2021099810A patent/JP7403841B2/ja active Active
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2023
- 2023-04-10 JP JP2023063437A patent/JP2023085519A/ja active Pending
- 2023-12-21 US US18/391,763 patent/US20240124836A1/en active Pending
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2024
- 2024-12-04 JP JP2024210817A patent/JP2025032187A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020182452A (ja) | 2020-11-12 |
| JP6903355B2 (ja) | 2021-07-14 |
| WO2016143826A1 (ja) | 2016-09-15 |
| US11891621B2 (en) | 2024-02-06 |
| US20240124836A1 (en) | 2024-04-18 |
| US20210024887A1 (en) | 2021-01-28 |
| US10836997B2 (en) | 2020-11-17 |
| JP2023085519A (ja) | 2023-06-20 |
| JP2025032187A (ja) | 2025-03-11 |
| US20180127714A1 (en) | 2018-05-10 |
| JP2021151252A (ja) | 2021-09-30 |
| JPWO2016143826A1 (ja) | 2018-02-15 |
| JP7403841B2 (ja) | 2023-12-25 |
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