JP6769962B2 - 癌治療のためのキナーゼ阻害剤プロドラッグ - Google Patents
癌治療のためのキナーゼ阻害剤プロドラッグ Download PDFInfo
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| JP2020533298A (ja) | 2017-09-08 | 2020-11-19 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ | Ｈｅｒ誘発性薬剤耐性がんの治療又は予防のための化合物、組成物及び方法 |
| JP7074760B2 (ja) | 2017-09-08 | 2022-05-24 | 大鵬薬品工業株式会社 | 抗腫瘍剤及び抗腫瘍効果増強剤 |
| ES2935729T3 (es) * | 2017-09-14 | 2023-03-09 | Lankenau Inst Medical Res | Métodos y composiciones para el tratamiento del cáncer |
| WO2019125184A1 (en) * | 2017-12-19 | 2019-06-27 | Auckland Uniservices Limited | Use of biomarker in cancer therapy |
| WO2020055643A2 (en) * | 2018-09-04 | 2020-03-19 | Rain Therapeutics Inc. | Compounds, compositions and methods for treating or preventing her-driven cancers |
| WO2020084347A2 (en) * | 2018-10-26 | 2020-04-30 | Auckland Uniservices | Combination of a kinase inhibitor and an immunotherapeutic agent, compositions and methods comprising the same |
| WO2020102304A1 (en) * | 2018-11-13 | 2020-05-22 | Rain Therapeutics Inc. | Combination of a kinase inhibitor and an electrolyte, compositions and methods comprising the same |
| WO2020118251A2 (en) * | 2018-12-07 | 2020-06-11 | The Board Of Trustees Of The Leland Stanford Junior University | Hypoxia targeting compositions and combinations thereof with a parp inhibitor and methods of use thereof |
| US11459391B2 (en) * | 2019-02-26 | 2022-10-04 | Janssen Biotech, Inc. | Combination therapies and patient stratification with bispecific anti-EGFR/c-Met antibodies |
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| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| TWI377944B (en) * | 2007-06-05 | 2012-12-01 | Hanmi Holdings Co Ltd | Novel amide derivative for inhibiting the growth of cancer cells |
| BRPI0912170A2 (pt) * | 2008-05-13 | 2015-10-13 | Astrazeneca Ab | composto, forma a, processo para a preparação da mesma, composição farmacêutica, uso de um composto, e, método para tratar um câncer em um animal de sangue quente |
| MX2011009034A (es) | 2009-03-11 | 2011-09-22 | Auckland Uniservices Ltd | Formas de profarmaco de inhibidores de cinasa y su uso en la terapia. |
| CN104496982A (zh) * | 2009-09-02 | 2015-04-08 | 奥克兰联合服务有限公司 | 激酶抑制剂、其前药形式及它们在治疗中的用途 |
| US20130288240A1 (en) * | 2010-05-21 | 2013-10-31 | Cell Signaling Technology, Inc. | Alk and ros kinase in cancer |
| US8828391B2 (en) | 2011-05-17 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Method for EGFR directed combination treatment of non-small cell lung cancer |
| PT3009431T (pt) * | 2011-07-27 | 2017-12-26 | Astrazeneca Ab | Compostos de 2-(2,4,5-anilino-substituídos)pirimidina como moduladores úteis do egfr para o tratamento do cancro |
| PL2922872T3 (pl) * | 2012-11-21 | 2019-03-29 | Janssen Biotech, Inc. | Bispecyficzne przeciwciała przeciwko egfr/c-met |
| BR112015023020A2 (pt) | 2013-03-14 | 2017-07-18 | Pfizer | combinação de inibidor de egfr t790m e inibidor de egfr para o tratamento de câncer pulmonar de células não-pequenas |
| US20160296538A1 (en) | 2013-04-10 | 2016-10-13 | Threshold Pharmaceuticals, Inc. | Predictive and response biomarker for th-302 anti-cancer therapy |
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| CN114224894B (zh) | 2025-01-07 |
| CN107427515B (zh) | 2021-11-16 |
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| JP2017536408A (ja) | 2017-12-07 |
| WO2016090174A1 (en) | 2016-06-09 |
| US10507210B2 (en) | 2019-12-17 |
| AU2015358384B2 (en) | 2021-03-04 |
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| US20170360790A1 (en) | 2017-12-21 |
| AU2015358384A1 (en) | 2017-06-29 |
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