JP6764790B2 - 視神経脊髄炎の治療に対する高可溶性アクアポリン−４細胞外ループペプチド免疫化 - Google Patents

視神経脊髄炎の治療に対する高可溶性アクアポリン−４細胞外ループペプチド免疫化 Download PDF

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JP6764790B2
JP6764790B2 JP2016568920A JP2016568920A JP6764790B2 JP 6764790 B2 JP6764790 B2 JP 6764790B2 JP 2016568920 A JP2016568920 A JP 2016568920A JP 2016568920 A JP2016568920 A JP 2016568920A JP 6764790 B2 JP6764790 B2 JP 6764790B2
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aqp4
nmo
loop
peptide
seq
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マイケル レヴィ，
マイケル レヴィ，
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ザ・ジョンズ・ホプキンス・ユニバーシティー
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JP2016568920A 2014-05-19 2015-05-19 視神経脊髄炎の治療に対する高可溶性アクアポリン−４細胞外ループペプチド免疫化 Active JP6764790B2 (ja)

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US201462000356P 2014-05-19 2014-05-19
US62/000,356 2014-05-19
PCT/US2015/031514 WO2015179360A1 (en) 2014-05-19 2015-05-19 Highly soluble aquaporin -4 extracelluar loop c peptide immunization for treatment of neuromyelitis optica

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JP2017523130A JP2017523130A (ja) 2017-08-17
JP2017523130A5 JP2017523130A5 (enExample) 2018-07-05
JP6764790B2 true JP6764790B2 (ja) 2020-10-07

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US (1) US20170080063A1 (enExample)
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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107643397A (zh) * 2017-07-26 2018-01-30 中国人民解放军总医院 一种用于视神经脊髓炎致病自身抗体分型的膜条
US11332527B2 (en) 2017-10-12 2022-05-17 Keio University Anti AQP3 monoclonal antibody specifically binding to extracellular domain of aquaporin 3 (AQP3) and use thereof
CN108129563B (zh) * 2018-01-12 2020-12-01 沈阳眼产业技术研究院有限公司 一种抗aqp4的小分子抗体及其应用
WO2020213084A1 (en) 2019-04-17 2020-10-22 Keio University Anti aqp3 monoclonal antibody specifically binding to extracellular domain of aquaporin 3 (aqp3) and use thereof
CN111272998A (zh) * 2020-01-09 2020-06-12 天津天海新域生物科技有限公司 一种同时检测中枢脱髓鞘自身抗体aqp4、mog和mbp的方法
US11858989B2 (en) 2020-12-22 2024-01-02 Lee Chao Lin Anti-AQP4 antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741671A (en) * 1991-12-12 1998-04-21 The Johns Hopkins University Isolation cloning and expression of transmembrane water channel aquaporin 1(AQP1)
GB0316878D0 (en) * 2003-07-18 2003-08-20 Letton Alan P Cooler food/drink container
US7101679B2 (en) * 2003-11-25 2006-09-05 Mayo Foundation For Medical Education And Research Marker for neuromyelitis optica
US9891219B2 (en) * 2008-10-10 2018-02-13 Mayo Foundation For Medical Education And Research Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive
GB0823366D0 (en) * 2008-12-22 2009-01-28 Uni I Oslo Synthesis
US9234017B2 (en) * 2012-12-11 2016-01-12 The Regents Of The University Of California Aquaporin-4 peptide compositions and methods of use thereof

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WO2015179360A1 (en) 2015-11-26
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EP3145528A4 (en) 2018-03-14

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