JP6751756B2 - 低密度リポタンパク質コレステロールレベルを低下させるためのｃｄ２４の使用 - Google Patents
低密度リポタンパク質コレステロールレベルを低下させるためのｃｄ２４の使用 Download PDFInfo
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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- C—CHEMISTRY; METALLURGY
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G—PHYSICS
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| US201562158157P | 2015-05-07 | 2015-05-07 | |
| US62/158,157 | 2015-05-07 | ||
| PCT/US2016/031109 WO2016179456A1 (en) | 2015-05-07 | 2016-05-06 | Use of cd24 for lowering low-density lipoprotein cholesterol levels |
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| JP2018515605A JP2018515605A (ja) | 2018-06-14 |
| JP2018515605A5 JP2018515605A5 (https=) | 2019-04-11 |
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| BR112017022394A2 (pt) * | 2015-05-07 | 2018-07-17 | Oncoimmune Inc | uso de cd24 para diminuir níveis de colesterol das lipoproteínas de baixa densidade |
| WO2018165204A1 (en) * | 2017-03-07 | 2018-09-13 | Oncoimmune, Inc. | Methods of use of soluble cd24 for treating systemic lupus erythematosus |
| WO2019113123A1 (en) * | 2017-12-04 | 2019-06-13 | Precithera, Inc. | TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING |
| JP2021523929A (ja) * | 2018-03-05 | 2021-09-09 | オンコイミューン， インコーポレイテッド | 後天性免疫不全症候群（ｈｉｖ／ａｉｄｓ）の治療のための可溶性ｃｄ２４の使用方法 |
| WO2019236474A1 (en) * | 2018-06-04 | 2019-12-12 | Oncoimmune, Inc. | Methods of use of cd24 for the prevention and treatment of leukemia relapse |
| EP3870604B1 (en) | 2018-10-26 | 2022-11-23 | F. Hoffmann-La Roche AG | Multispecific antibody screening method using recombinase mediated cassette exchange |
| EP3921338A4 (en) * | 2019-02-06 | 2022-11-23 | Oncoimmune Inc. | TARGETED CD24-SIGLEC INTERACTIONS TO TREAT AND PREVENT NON-ALCOHOLIC STEATOHEPATITIS |
| US20220000974A1 (en) * | 2019-02-06 | 2022-01-06 | Oncolmmune, Inc. | Targeting CD24-Siglec Interactions for Treating Subjects with Prediabetes or Diabetes |
| WO2021160173A1 (en) * | 2020-02-10 | 2021-08-19 | Oncoimmune, Inc. | Methods of use of soluble cd24 for treating viral pneumonia |
| WO2021160170A1 (en) * | 2020-02-10 | 2021-08-19 | Oncoimmune, Inc. | Methods of use of soluble cd24 for treating sars-cov-2 infection |
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| US6544566B1 (en) * | 1999-04-23 | 2003-04-08 | Protein Technologies International, Inc. | Composition containing plant sterol, soy protein and isoflavone for reducing LDL cholesterol |
| EP1267909B1 (en) * | 2000-03-29 | 2010-07-28 | The Ohio State University Research Foundation | Methods of blocking tissue destruction by autoreactive t cells |
| CN1323544A (zh) * | 2000-05-13 | 2001-11-28 | 蛋白质技术国际公司 | 降低低密度脂蛋白胆固醇浓度的组合物和方法 |
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| US8163281B2 (en) * | 2009-03-04 | 2012-04-24 | The Regents Of The University Of Michigan | Treatment of drug-related side effect and tissue damage by targeting the CD24-HMGB1-Siglec10 axis |
| US8354520B2 (en) * | 2009-12-10 | 2013-01-15 | Kaohsiung Medical University | Composition and method for treating atherosclerosis, method for determining if a subject has atherosclerosis and method of screening an anti-atherosclerotic drug |
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| AU2012267489B2 (en) * | 2011-06-10 | 2017-03-16 | The Trustees Of The University Of Pennsylvania | System and method of cytomic vascular health profiling |
| BR112017022394A2 (pt) * | 2015-05-07 | 2018-07-17 | Oncoimmune Inc | uso de cd24 para diminuir níveis de colesterol das lipoproteínas de baixa densidade |
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| AU2016258084B2 (en) | 2020-01-30 |
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| US11026995B2 (en) | 2021-06-08 |
| US10369197B2 (en) | 2019-08-06 |
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| US20190307841A1 (en) | 2019-10-10 |
| EP3292144B1 (en) | 2020-08-26 |
| MX385941B (es) | 2025-03-18 |
| AU2016258084A1 (en) | 2017-11-02 |
| JP2018515605A (ja) | 2018-06-14 |
| EP3292144A1 (en) | 2018-03-14 |
| PT3292144T (pt) | 2020-11-05 |
| IL255086A0 (en) | 2017-12-31 |
| HUE051866T2 (hu) | 2021-03-29 |
| CN107531772B (zh) | 2021-09-21 |
| BR112017022394A2 (pt) | 2018-07-17 |
| ZA201706846B (en) | 2018-12-19 |
| HK1249521A1 (zh) | 2018-11-02 |
| HRP20201651T1 (hr) | 2020-12-25 |
| KR20170141216A (ko) | 2017-12-22 |
| MX2017014095A (es) | 2018-03-16 |
| IL255086B (en) | 2021-08-31 |
| EA038520B1 (ru) | 2021-09-09 |
| CN107531772A (zh) | 2018-01-02 |
| US20180110828A1 (en) | 2018-04-26 |
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