JP6693747B2 - 植物体中のたばこ特異的ニトロソアミンの低減 - Google Patents

植物体中のたばこ特異的ニトロソアミンの低減 Download PDF

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Publication number
JP6693747B2
JP6693747B2 JP2015548608A JP2015548608A JP6693747B2 JP 6693747 B2 JP6693747 B2 JP 6693747B2 JP 2015548608 A JP2015548608 A JP 2015548608A JP 2015548608 A JP2015548608 A JP 2015548608A JP 6693747 B2 JP6693747 B2 JP 6693747B2
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plant
seq
plants
tobacco
sequence
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JP2016508032A5 (https=
JP2016508032A (ja
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ルシアン ボヴェ
ルシアン ボヴェ
プリスカ カンパノーニ
プリスカ カンパノーニ
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フィリップ・モーリス・プロダクツ・ソシエテ・アノニム
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/245—Nitrosamines
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B3/00—Preparing tobacco in the factory
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacture Of Tobacco Products (AREA)
JP2015548608A 2012-12-21 2013-12-19 植物体中のたばこ特異的ニトロソアミンの低減 Active JP6693747B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12198966.9 2012-12-21
EP12198966 2012-12-21
PCT/EP2013/077532 WO2014096283A2 (en) 2012-12-21 2013-12-19 Tobacco specific nitrosamine reduction in plants

Publications (3)

Publication Number Publication Date
JP2016508032A JP2016508032A (ja) 2016-03-17
JP2016508032A5 JP2016508032A5 (https=) 2017-03-02
JP6693747B2 true JP6693747B2 (ja) 2020-05-13

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ID=47559184

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JP2015548608A Active JP6693747B2 (ja) 2012-12-21 2013-12-19 植物体中のたばこ特異的ニトロソアミンの低減

Country Status (11)

Country Link
US (1) US10563215B2 (https=)
EP (1) EP2935588B1 (https=)
JP (1) JP6693747B2 (https=)
KR (1) KR102253223B1 (https=)
CN (1) CN105247053B (https=)
AP (1) AP2015008563A0 (https=)
CA (1) CA2894955C (https=)
MX (2) MX2015008084A (https=)
PH (1) PH12015501204B1 (https=)
RU (1) RU2735254C2 (https=)
WO (1) WO2014096283A2 (https=)

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GB201501941D0 (en) * 2015-02-05 2015-03-25 British American Tobacco Co Method
WO2016179356A1 (en) * 2015-05-05 2016-11-10 North Carolina State University Methods and compositions for reducing the tobacco specific nitrosamine nnk in tobacco
WO2017156535A1 (en) * 2016-03-11 2017-09-14 Altria Client Services Llc Compositions and methods for producing tobacco plants and products having reduced or eliminated suckers
AR112465A1 (es) 2017-07-31 2019-10-30 Reynolds Tobacco Co R Métodos y composiciones para la edición de genes de base viral en plantas
AR115023A1 (es) 2018-03-28 2020-11-18 Philip Morris Products Sa Modulación del contenido de azúcar reductor en una planta
AR115022A1 (es) 2018-03-28 2020-11-18 Philip Morris Products Sa Modulación del contenido de aminoácidos en una planta
GB201812603D0 (en) 2018-08-02 2018-09-19 British American Tobacco Investments Ltd Method
US11976286B2 (en) 2018-12-30 2024-05-07 Philip Morris Products S.A. Modulation of nitrate levels in plants via mutation of nitrate reductase
US12344853B2 (en) * 2019-06-05 2025-07-01 University Of Kentucky Research Foundation bZIP transcription factors regulate conversion of nicotine to nornicotine and reduce levels of tobacco specific (TSNA) precursors
CN110499388B (zh) * 2019-09-29 2023-03-24 云南省烟草农业科学研究院 鉴别烟草抗斑萎病位点rtsw等位基因类型的共显性标记引物组、鉴别方法及其应用
JP2022552638A (ja) 2019-10-01 2022-12-19 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 植物における糖およびアミノ酸含有量の調節（ｓｕｌｔｒ３）
JP7659547B2 (ja) 2019-10-01 2025-04-09 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 植物における還元糖含有量の調節（ｉｎｖ）
CN111690661A (zh) * 2020-06-01 2020-09-22 云南省烟草农业科学研究院 一种烟草NtbHLH13基因突变体及分子鉴定方法和应用
US20240368615A1 (en) 2021-09-10 2024-11-07 Philip Morris Products S.A. Modulating alkaloid profiles in nicotiana tabacum
WO2023117661A1 (en) 2021-12-20 2023-06-29 Philip Morris Products S.A. Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase
WO2023117701A1 (en) 2021-12-21 2023-06-29 Philip Morris Products S.A. Modulation of nicotine production by alteration of nicotinamidase expression or function in plants
KR20240112979A (ko) 2021-12-27 2024-07-19 니뽄 다바코 산교 가부시키가이샤 담배 식물
JP2025533986A (ja) 2022-10-13 2025-10-09 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム Ｎｔｐ２を調節することによって葉バイオマスおよび窒素利用効率を増加させる
EP4658670A1 (en) 2023-02-02 2025-12-10 Philip Morris Products S.A. Modulation of genes coding for lysine ketoglutarate reductase
JP2026506774A (ja) 2023-02-02 2026-02-26 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 糖トランスポーターの調節
CN121335615A (zh) 2023-06-29 2026-01-13 菲利普莫里斯生产公司 编码谷氨酸脱氢酶的基因的调节
CN117025627B (zh) * 2023-06-29 2024-11-01 中国烟草总公司郑州烟草研究院 烟草氯离子通道蛋白NtCLC13及其编码基因和应用
CN117025626B (zh) * 2023-06-29 2025-02-14 中国烟草总公司郑州烟草研究院 烟草硝酸盐转运蛋白NtNPF7.4及其编码基因、基因编辑载体和应用
CN120944912A (zh) * 2025-09-17 2025-11-14 河南省农业科学院烟草研究所 NtGCN1基因及其在调控烟叶氯离子含量中的应用

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KR20120126061A (ko) * 2009-10-22 2012-11-20 재단법인 작물유전체기능연구사업단 향상된 수확량 관련 형질을 갖는 식물 및 이의 제조 방법
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CN103228671B (zh) 2010-09-03 2017-08-15 菲利普莫里斯产品有限公司 植物中的重金属减少

Also Published As

Publication number Publication date
CA2894955A1 (en) 2014-06-26
CA2894955C (en) 2023-10-31
US20150315603A1 (en) 2015-11-05
EP2935588A2 (en) 2015-10-28
WO2014096283A3 (en) 2014-08-14
EP2935588B1 (en) 2026-03-25
CN105247053B (zh) 2020-07-31
JP2016508032A (ja) 2016-03-17
CN105247053A (zh) 2016-01-13
MX2015008084A (es) 2016-03-31
PH12015501204B1 (en) 2022-07-15
MX2019001598A (es) 2019-07-01
RU2015126909A (ru) 2017-01-27
KR102253223B1 (ko) 2021-05-21
PH12015501204A1 (en) 2015-08-17
RU2735254C2 (ru) 2020-10-29
WO2014096283A2 (en) 2014-06-26
KR20150096451A (ko) 2015-08-24
US10563215B2 (en) 2020-02-18
AP2015008563A0 (en) 2015-06-30

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