JP6689613B2 - Antibacterial and antiviral composition for textiles and textile products - Google Patents
Antibacterial and antiviral composition for textiles and textile products Download PDFInfo
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- JP6689613B2 JP6689613B2 JP2016015889A JP2016015889A JP6689613B2 JP 6689613 B2 JP6689613 B2 JP 6689613B2 JP 2016015889 A JP2016015889 A JP 2016015889A JP 2016015889 A JP2016015889 A JP 2016015889A JP 6689613 B2 JP6689613 B2 JP 6689613B2
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- Agricultural Chemicals And Associated Chemicals (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Description
本発明は、繊維用抗菌・抗ウイルス性組成物および繊維製品に関する。 The present invention relates to an antibacterial / antiviral composition for textiles and textiles.
従来より、微粒子状の銀や亜鉛などの金属を含む抗菌・抗ウイルス性組成物が知られている（例えば特許文献１〜６など）。 BACKGROUND ART Conventionally, antibacterial / antiviral compositions containing fine particles of metals such as silver and zinc have been known (for example, Patent Documents 1 to 6).
また、例えば、抗菌・抗ウイルス性を有する繊維製品も提案されている（特許文献７、８）。 Further, for example, textile products having antibacterial / antiviral properties have also been proposed (Patent Documents 7 and 8).
しかしながら、例えば、特許文献１〜６の抗菌・抗ウイルス性組成物を繊維に塗布などした場合、抗菌・抗ウイルス性成分が繊維から脱落しやすく、抗菌・抗ウイルス性を長期間に亘って維持することは難しい。また、抗菌・抗ウイルス性組成物に銀などの金属が含まれる場合、変色が生じる恐れがある。 However, for example, when the antibacterial / antiviral composition of Patent Documents 1 to 6 is applied to a fiber, the antibacterial / antiviral component is likely to drop from the fiber, and the antibacterial / antiviral property is maintained for a long period of time. Difficult to do. Further, when the antibacterial / antiviral composition contains a metal such as silver, discoloration may occur.
また、特許文献７、８の繊維製品の場合も、抗菌・抗ウイルス性成分が繊維から脱落しやすく、また、抗菌・抗ウイルス性効果も次第に低下していくという問題がある。さらに、特許文献７、８の繊維製品の場合、染料や顔料を用いての染色や、柔軟化、加工溶剤の使用などによっても抗菌・抗ウイルス性効果が阻害される恐れがあるため、使用可能な材料が大きく制限されてしまうという問題もある。 Also, in the case of the textile products of Patent Documents 7 and 8, there is a problem that the antibacterial / antiviral component is likely to drop from the fiber, and the antibacterial / antiviral effect is gradually reduced. Furthermore, in the case of the textile products of Patent Documents 7 and 8, the antibacterial / antiviral effect may be impaired by dyeing with a dye or pigment, softening, use of a processing solvent, etc. There is also a problem that such materials are greatly limited.
本発明は、以上の事情に鑑みてなされたものであり、抗菌・抗ウイルス性成分の繊維からの脱落や変色が抑制され、優れた抗菌・抗ウイルス効果を長期間維持することができ、使用可能な材料の制限も少ない繊維用抗菌・抗ウイルス性組成物と、この繊維用抗菌・抗ウイルス性組成物が塗布または含浸された繊維製品を提供することを課題としている。 The present invention has been made in view of the above circumstances, and it is possible to suppress discoloration and discoloration of an antibacterial / antiviral component from the fiber and maintain an excellent antibacterial / antiviral effect for a long period of time. It is an object of the present invention to provide an antibacterial / antiviral composition for fibers with less possible restrictions on materials and a fiber product coated or impregnated with the antibacterial / antiviral composition for fibers.
上記の課題を解決するため、本発明の繊維用抗菌・抗ウイルス性組成物は、アミノ酸銀、アミノ酸亜鉛および銅イオンを含むことを特徴としている。 In order to solve the above problems, the antibacterial / antiviral composition for fibers of the present invention is characterized by containing amino acid silver, amino acid zinc and copper ion.
この繊維用抗菌・抗ウイルス性組成物では、アミノ酸銀およびアミノ酸亜鉛のアミノ酸は、Ｌ−ピロリドンカルボン酸であることが好ましい。 In this antibacterial / antiviral composition for fibers, the amino acids of amino acid silver and amino acid zinc are preferably L-pyrrolidone carboxylic acid.
この繊維用抗菌・抗ウイルス性組成物では、銅イオンは、ピロリドンカルボン酸銅によるものであることが好ましい。 In this antibacterial / antiviral composition for fibers, the copper ion is preferably copper pyrrolidonecarboxylate.
この繊維用抗菌・抗ウイルス性組成物では、さらに、硫酸を含むことが好ましい。 This antibacterial / antiviral composition for fibers preferably further contains sulfuric acid.
この繊維用抗菌・抗ウイルス性組成物では、さらに、Ｎ−長鎖アシルアミノ酸カリウムを含むことが好ましい。 The antibacterial / antiviral composition for fibers preferably further contains potassium N-long chain acylamino acid.
この繊維用抗菌・抗ウイルス性組成物では、さらに、グルタミン酸を含むことが好ましい。 This antibacterial / antiviral composition for fibers preferably further contains glutamic acid.
この繊維用抗菌・抗ウイルス性組成物では、さらに、クエン酸を含むことが好ましい。 This antibacterial / antiviral composition for fibers preferably further contains citric acid.
本発明の繊維製品は、繊維に、上記の繊維用抗菌・抗ウイルス性組成物が塗布または含浸されている。 In the fiber product of the present invention, fibers are coated or impregnated with the above-mentioned antibacterial / antiviral composition for fibers.
本発明の繊維用抗菌・抗ウイルス性組成物は、溶媒としての水中に、アミノ酸銀、アミノ酸亜鉛および銅イオンを含んでいる。本発明の抗菌・抗ウイルス性組成物では、配合されたアミノ酸銀、アミノ酸亜鉛のうちの少なくとも一部の銀、亜鉛はイオン化した状態で存在している。 The antibacterial / antiviral composition for fibers of the present invention contains silver amino acid, zinc amino acid, and copper ion in water as a solvent. In the antibacterial / antiviral composition of the present invention, at least a part of silver and zinc of amino acids and zinc which are blended are present in an ionized state.
アミノ酸銀およびアミノ酸亜鉛におけるアミノ酸としては、例えば、グリシン、アラニン、バリン、ロイシン、フェニルアラニン、チロシン、トレオニン、トリプトファン、メチオニン、アスパラギン酸、リジン、アルギニン、ヒスチジンピドール酸、Ｌ−グルタミン酸、Ｌ−グルチム酸、Ｌ−グルチミン酸、Ｌ−グルタミン酸ラクタム、Ｌ−グルチミニン酸、Ｌ−ピロリドンカルボン酸、Ｌ−ピログルタミン酸、オキソプロリンのうちの１種または２種以上を例示することができる。これらの中でも、Ｌ−ピロリドンカルボン酸は、抗菌・抗ウイルス効果に優れているため、本発明の抗菌・抗ウイルス性組成物に、ピロリドンカルボン酸銀、ピロリドンカルボン酸亜鉛を配合することで、抗菌・抗ウイルス効果を確実に高めることができる。 Examples of amino acids in the amino acid silver and amino acid zinc include glycine, alanine, valine, leucine, phenylalanine, tyrosine, threonine, tryptophan, methionine, aspartic acid, lysine, arginine, histidine pidolic acid, L-glutamic acid, L-glutimic acid. , L-glutamic acid, L-glutamic acid lactam, L-glutiminic acid, L-pyrrolidone carboxylic acid, L-pyroglutamic acid, and oxoproline. Among these, L-pyrrolidone carboxylic acid is excellent in antibacterial and antiviral effects, and therefore, antibacterial and antiviral compositions of the present invention are blended with silver pyrrolidonecarboxylate and zinc pyrrolidonecarboxylate to provide antibacterial properties. -The antiviral effect can be reliably enhanced.
アミノ酸銀およびアミノ酸亜鉛の配合量は適宜設計することができるが、例えば、水１０００ｍｌに対する銀イオンおよび亜鉛イオンの合計が１５０００ｍｇ／Ｌ以上であることが好ましく、実際的には、水１０００ｍｌに対する銀イオンおよび亜鉛イオンの合計が、１５０００ｍｇ／Ｌ〜１０００００ｍｇ／Ｌ程度の範囲であることがより好ましい。 The blending amount of amino acid silver and amino acid zinc can be appropriately designed, but for example, the total of silver ion and zinc ion per 1000 ml of water is preferably 15000 mg / L or more, and practically, silver ion per 1000 ml of water is preferred. More preferably, the total of zinc ions and zinc ions is in the range of about 15,000 mg / L to 100,000 mg / L.
本発明の繊維用抗菌・抗ウイルス性組成物に含まれる銅イオンは、各種の銅化合物によるものであってよく、具体的には、例えば、硝酸銅、塩化銅、硫酸銅、酸化銅、硫酸銅、ヨウ化銅、炭酸銅、クエン酸銅、グルタミン酸銅、アミノ酸銅等うちの１種または２種以上を例示することができ、なかでもアミノ酸銅であることが好ましい。 The copper ion contained in the antibacterial / antiviral composition for fibers of the present invention may be derived from various copper compounds, and specifically, for example, copper nitrate, copper chloride, copper sulfate, copper oxide, sulfuric acid. One or more of copper, copper iodide, copper carbonate, copper citrate, copper glutamate, copper amino acid and the like can be exemplified, and among them, amino acid copper is preferable.
アミノ酸銅のアミノ酸は、アミノ酸銀およびアミノ酸亜鉛と同様に、例えば、グリシン、アラニン、バリン、ロイシン、フェニルアラニン、チロシン、トレオニン、トリプトファン、メチオニン、アスパラギン酸、リジン、アルギニン、ヒスチジンピドール酸、Ｌ−グルタミン酸、Ｌ−グルチム酸、Ｌ−グルチミン酸、Ｌ−グルタミン酸ラクタム、Ｌ−グルチミニン酸、Ｌ−ピロリドンカルボン酸、Ｌ−ピログルタミン酸、オキソプロリンのうちの１種または２種以上を例示することができる。これらの中でも、Ｌ−ピロリドンカルボン酸は、抗菌・抗ウイルス効果に優れているため、本発明の抗菌・抗ウイルス性組成物に、ピロリドンカルボン酸銅を配合することで、抗菌・抗ウイルス効果を確実に高めることができる。 Amino acids of the amino acid copper include, for example, glycine, alanine, valine, leucine, phenylalanine, tyrosine, threonine, tryptophan, methionine, aspartic acid, lysine, arginine, histidine pidolic acid, and L-glutamic acid, like the amino acid silver and zinc amino acid. , L-glutamic acid, L-glutamic acid, L-glutamic acid lactam, L-glutiminic acid, L-pyrrolidone carboxylic acid, L-pyroglutamic acid and oxoproline can be exemplified. Among these, L-pyrrolidonecarboxylic acid is excellent in antibacterial and antiviral effects, and therefore antibacterial and antiviral effects can be obtained by adding copper pyrrolidonecarboxylic acid to the antibacterial and antiviral composition of the present invention. It can surely be increased.
アミノ酸銅の配合量は適宜設計することができるが、例えば、水１０００ｍｌに対する銅イオンが１００ｍｇ／Ｌ以上であることが好ましく、実際的には、水１０００ｍｌに対する銀イオンおよび亜鉛イオンの合計が、１００ｍｇ／Ｌ〜５００ｍｇ／Ｌ程度の範囲であることがより好ましい。 The amount of the amino acid copper compounded can be appropriately designed, but for example, it is preferable that the copper ion in 1000 ml of water is 100 mg / L or more, and practically, the total of silver ion and zinc ion in 1000 ml of water is 100 mg. / L to 500 mg / L is more preferable.
また、本発明の繊維用抗菌・抗ウイルス性組成物には、例えば、ニッケル、マグネシウム、鉄、チタンなどのその他の金属を適宜含むことができる。 Further, the antibacterial / antiviral composition for fibers of the present invention can appropriately contain other metals such as nickel, magnesium, iron and titanium.
さらに、本発明の繊維用抗菌・抗ウイルス性組成物は、界面活性剤として、Ｎ―長錯アシルアミノ酸カリウムを含むことが好ましい。Ｎ―長錯アシルアミノ酸カリウムは、カリウムイオンが容易に抗ウイルス性組成物の銀イオン、亜鉛イオン、銅イオンと結合し、効果的に繊維と結合する。このため、Ｎ―長錯アシルアミノ酸カリウムは、抗ウイルス性成分を保持する役割を有している。また、Ｎ―長錯アシルアミノ酸カリウムは、界面活性剤として繊維の内部への繊維用抗菌・抗ウイルス性組成物の浸透性とpHによる凝集性を高めることができる。繊維用抗菌・抗ウイルス性組成物が繊維の内部へ浸透した後、凝集することで、繊維用抗菌・抗ウイルス性組成物が繊維に固定されるため、脱落が抑制され、抗菌・抗ウイルス性を長期間維持することができる。 Furthermore, the antibacterial / antiviral composition for fibers of the present invention preferably contains potassium N-long complex acylamino acid as a surfactant. The potassium ion of the N-long complex acylamino acid readily binds to the silver ion, zinc ion, and copper ion of the antiviral composition and effectively binds to the fiber. Therefore, the N-long complex acylamino acid potassium has a role of retaining the antiviral component. In addition, the N-long complex acylamino acid potassium, as a surfactant, can enhance the permeability of the antibacterial / antiviral composition for fibers into the inside of the fibers and the cohesiveness due to pH. After the antibacterial / antiviral composition for fibers permeates the inside of the fiber and then aggregates, the antibacterial / antiviral composition for fibers is fixed to the fibers, so that the dropout is suppressed and the antibacterial / antiviral properties are suppressed. Can be maintained for a long time.
本発明の繊維用抗菌・抗ウイルス性組成物とＮ―長錯アシルアミノ酸カリウムの配合割合は、用途、目的など応じて適宜設定することができるが、例えば、抗菌・抗ウイルス性組成物に対して、０．００５重量％〜１０重量％の範囲内を例示することができる。Ｎ―長錯アシルアミノ酸カリウムの配合割合がこの範囲であると、上記の効果が確実に発揮される。 The blending ratio of the antibacterial / antiviral composition for fibers of the present invention and potassium N-long complex acylamino acid potassium can be appropriately set depending on the use, purpose and the like. For example, for the antibacterial / antiviral composition, Thus, a range of 0.005% by weight to 10% by weight can be exemplified. If the blending ratio of the N-long complex acylamino acid potassium is in this range, the above-mentioned effects are surely exhibited.
また、本発明の抗菌・抗ウイルス性組成物には、塩酸、硝酸、リン酸、酢酸、硫酸などの各種の酸類を配合することで、凝集性を高めることができる。これらの中でも、金属イオンの溶解性と浸透性（浸透安定性）の観点から、硫酸が好ましい。本発明の抗菌・抗ウイルス性組成物における硫酸などの各種の酸類の濃度などは特に限定されず、抗菌・抗ウイルス性を妨げない範囲で適宜設定することができる。 In addition, the antibacterial / antiviral composition of the present invention may contain various acids such as hydrochloric acid, nitric acid, phosphoric acid, acetic acid, sulfuric acid, etc. to enhance cohesiveness. Among these, sulfuric acid is preferable from the viewpoint of solubility and permeability (permeation stability) of metal ions. The concentration of various acids such as sulfuric acid in the antibacterial / antiviral composition of the present invention is not particularly limited, and can be appropriately set within a range not impairing the antibacterial / antiviral property.
本発明の抗菌・抗ウイルス性組成物には、グルタミン酸を配合することが好ましい。グルタミン酸は、水に対する溶解性、カルボン酸系材料との相関性に優れ、ピロリドンカルボン酸の原料ともなるため、繊維に対する浸透性をさらに高めることができる。 Glutamic acid is preferably added to the antibacterial / antiviral composition of the present invention. Glutamic acid has excellent solubility in water and correlation with a carboxylic acid-based material, and also serves as a raw material for pyrrolidonecarboxylic acid, so that it is possible to further enhance the permeability to fibers.
また、本発明の抗菌・抗ウイルス性組成物には、クエン酸を配合することが好ましい。クエン酸は溶解性に優れ、繊維への浸透性をさらに高めることができる。 Further, it is preferable to add citric acid to the antibacterial / antiviral composition of the present invention. Citric acid has excellent solubility and can further enhance the permeability into fibers.
さらに、本発明の抗菌・抗ウイルス性組成物には、用途、取り扱い性、保存性などを考慮して、その他各種の添加物を配合することができる。例えば、通常製剤に用いられる配合剤、例えば、界面活性剤、油分、アルコール類、保湿剤、増粘剤、防腐剤、酸化防止剤、キレート剤、ｐＨ調整剤、香料、色素、ビタミン類、生薬、植物エキス等を配合することもできる。また、硫酸亜鉛七水和物、硫酸銅五水和物などの酸や水酸化ナトリウムなどを利用してｐＨを調整することもできる。 Further, the antibacterial / antiviral composition of the present invention can be blended with various other additives in consideration of use, handleability, storability and the like. For example, compounding agents usually used in preparations such as surfactants, oils, alcohols, humectants, thickeners, preservatives, antioxidants, chelating agents, pH adjusters, fragrances, pigments, vitamins, crude drugs , A plant extract or the like can also be added. The pH can also be adjusted by using an acid such as zinc sulfate heptahydrate or copper sulfate pentahydrate or sodium hydroxide.
本発明の繊維製品は、上記の通りの抗菌・抗ウイルス性組成物が、繊維に塗布または含浸されている。 In the textile product of the present invention, the antibacterial / antiviral composition as described above is applied to or impregnated in the fiber.
繊維製品は、抗菌・抗ウイルス性組成物が塗布または含浸された繊維を少なくとも一部に含み、糸、織編物、ウェブ、不織布、紙、ネット等に成形されたものを材料とすることができる。具体的には、例えば、繊維製品としては、例えば、衣類(帽子、手袋、ハンカチを含む)、寝具（布団、枕を含む）、カーテン、壁紙、カーペット、マット、シーツ、フィルター、マスク、ワイパー、タオル、防護衣類、防護ネットなどを例示することができ、日常の生活に供され、生活空間に飛散浮遊する菌やウイルスを不活化させることができる。 The fiber product may include, as at least a part thereof, a fiber coated or impregnated with an antibacterial / antiviral composition and formed into a thread, a woven or knitted material, a web, a non-woven fabric, a paper, a net, or the like. . Specifically, for example, as textile products, for example, clothing (including hats, gloves, handkerchiefs), bedding (including duvets and pillows), curtains, wallpaper, carpets, mats, sheets, filters, masks, wipers, Examples include towels, protective clothing, protective nets, etc., which can inactivate bacteria and viruses that are used in daily life and that are scattered in the living space.
また、繊維の材料は特に限定されないが、例えばセルロース系繊維（木綿、麻、レーヨン、パルプなど）、蛋白質系繊維（羊毛、絹など）、ポリアミド系繊維、ポリエステル系繊維、ポリアクリル系繊維、ポリビニルアルコール系繊維、ポリ塩化ビニル系繊維、ポリ塩化ビニリデン系繊維、ポリオレフィン系繊維、ポリウレタン系繊維などの各種の天然繊維、再生繊維、半合成繊維、合成繊維を使用できる。 The material of the fiber is not particularly limited, and examples thereof include cellulosic fiber (cotton, hemp, rayon, pulp, etc.), protein fiber (wool, silk, etc.), polyamide fiber, polyester fiber, polyacrylic fiber, polyvinyl. Various natural fibers such as alcohol fibers, polyvinyl chloride fibers, polyvinylidene chloride fibers, polyolefin fibers, polyurethane fibers, regenerated fibers, semi-synthetic fibers, and synthetic fibers can be used.
さらに、抗菌・抗ウイルス性組成物を繊維に塗布または含浸する方法も特に限定されない。例えば、材料となる繊維または繊維製品を抗菌・抗ウイルス性組成物を含む溶液に浸漬して乾燥させる方法や、材料となる繊維または繊維製品に対して抗菌・抗ウイルス性組成物を含む溶液を噴霧またはコーティングして乾燥させる方法などを例示することができる。 Furthermore, the method of applying or impregnating the fiber with the antibacterial / antiviral composition is not particularly limited. For example, a method of immersing a material fiber or textile product in a solution containing an antibacterial / antiviral composition and drying it, or a solution containing an antibacterial / antiviral composition for the material fiber or textile product is used. The method of spraying or coating and drying can be illustrated.
本発明の抗菌・抗ウイルス性組成物は、アミノ酸銀、アミノ酸亜鉛および銅イオンなどを含むため、抗菌・抗ウイルス性成分の繊維からの脱落や変色が抑制され、優れた抗菌・抗ウイルス効果を長期間維持することができる。また、繊維に塗布、含浸された本発明の抗菌・抗ウイルス性組成物の抗菌・抗ウイルス効果は染料、顔料、柔軟剤、加工溶剤などの他の材料によって阻害され難く、材料の使用制限も少ない。そして、このような抗菌・抗ウイルス性組成物が塗布または含浸されている繊維製品は、生活空間に飛散浮遊する菌やウイルスを不活化させることができ、優れた抗菌・抗ウイルス性を持続することができる。 Since the antibacterial / antiviral composition of the present invention contains the amino acid silver, the amino acid zinc, copper ion, etc., the antibacterial / antiviral component is prevented from being discolored or discolored from the fiber and has an excellent antibacterial / antiviral effect. Can be maintained for a long time. In addition, the antibacterial and antiviral effects of the antibacterial and antiviral composition of the present invention applied and impregnated on the fiber are not easily inhibited by other materials such as dyes, pigments, softeners and processing solvents, and the use of the material is restricted. Few. A textile product coated or impregnated with such an antibacterial / antiviral composition can inactivate bacteria and viruses scattered in the living space and maintain excellent antibacterial / antiviral properties. be able to.
本発明の抗菌・抗ウイルス性組成物は、以上の実施形態に限定されることはない。 The antibacterial / antiviral composition of the present invention is not limited to the above embodiments.
以下、実施例とともに本発明の抗菌・抗ウイルス性組成物について説明するが、本発明の抗菌・抗ウイルス性組成物は、以下の実施例に何ら限定されるものではない。 Hereinafter, the antibacterial / antiviral composition of the present invention will be described together with examples, but the antibacterial / antiviral composition of the present invention is not limited to the following examples.
＜実施例１＞抗菌・抗ウイルス性組成物の作製
以下の手順で、抗菌・抗ウイルス性組成物を作製した。
（１）純水１０００ｍｌ中に、硝酸銀０．１ｍｏｌと炭酸水素ナトリウム０．１ｍｏｌを添加し、常温、遮光した室内で添加後１０分間攪拌した。
（２）濾過紙を用いて脱水し、純水１０００ｍｌで洗浄を行った。
（３）上記（２）によって得られた乾燥重量６．７５ｇ相当のペーストと、Ｌ−ピロリドンカルボン酸６．９６ｇとを純水１０００ｍｌに加えて、加温反応させることでピロリドンカルボン酸銀１０００ｍｇ／Ｌを得た。
（４）上記（１）（２）（３）と同様に、硝酸亜鉛を材料として、Ｌ−ピロリドンカルボン酸と反応させ、ピロリドンカルボン酸亜鉛（亜鉛：８２％、ピロリドンカルボン酸化合物：１８％）１６．５ｇ（乾燥重量）を得た。
（５）ピロリドンカルボン酸銀、Ｌ−ピロリドンカルボン酸亜鉛、硫酸銅五水和物を以下のように配合し、抗菌・抗ウイルス性組成物を作製した。
水１０００ｍｌ中の配合
上記記載のピロリドンカルボン酸銀 １００ｍｇ／Ｌ
Ｌ−ピロリドンカルボン酸亜鉛 １６５００ｍｇ／Ｌ
硫酸銅五水和物 ２４００ｍｇ／Ｌ
なお、この組成物は長時間経過しても変色が生じないことが確認された。
<Example 1> Preparation of antibacterial / antiviral composition An antibacterial / antiviral composition was prepared by the following procedure.
(1) To 1000 ml of pure water, 0.1 mol of silver nitrate and 0.1 mol of sodium hydrogen carbonate were added, and the mixture was stirred at room temperature in a light-shielded room and stirred for 10 minutes.
(2) It was dehydrated using a filter paper and washed with 1000 ml of pure water.
(3) A paste having a dry weight of 6.75 g obtained in the above (2) and 6.96 g of L-pyrrolidonecarboxylic acid were added to 1000 ml of pure water and reacted by heating to give 1000 mg of silver pyrrolidonecarboxylate / L was obtained.
(4) Similar to the above (1), (2) and (3), zinc nitrate was used as a material and reacted with L-pyrrolidonecarboxylic acid to give zinc pyrrolidonecarboxylate (zinc: 82%, pyrrolidonecarboxylic acid compound: 18%). 16.5 g (dry weight) was obtained.
(5) Silver pyrrolidonecarboxylate, zinc L-pyrrolidonecarboxylate, and copper sulfate pentahydrate were blended as follows to prepare an antibacterial / antiviral composition.
Formulation in 1000 ml of water Silver pyrrolidonecarboxylate described above 100 mg / L
Zinc L-pyrrolidone carboxylate 16500 mg / L
Copper sulfate pentahydrate 2400mg / L
It was confirmed that this composition did not cause discoloration even after a long time.
＜実施例２＞組成物の消臭性
（１）実施例１で作製した組成物をレーヨン原料に対し１／２００の割合で混合し、以下の条件で消臭性を試験した。
<Example 2> Deodorizing property of composition (1) The composition prepared in Example 1 was mixed with a rayon raw material at a ratio of 1/200, and the deodorizing property was tested under the following conditions.
試験方法：（一社）繊維評価技術評議会ＳＥＫマーク繊維製品認証基準２１．消臭試験（検知管法、ガスクロマトグラフ法）
ガス初発濃度：アンモニア１００ｐｐｍ、酢酸３０ｐｐｍ、イソ吉草酸３８ｐｐｍ
試験試料：検知管法１００ｃｍ２、ガスクロマトグラフ法５０ｃｍ２
測定時間：２時間後
（２）結果を表１に示す。
Test method: (1 company) Textile Evaluation Technology Council SEK mark Textile product certification standard 21. Deodorization test (detection tube method, gas chromatograph method)
Gas initial concentration: Ammonia 100ppm, acetic acid 30ppm, isovaleric acid 38ppm
Test sample: Detector tube method 100 cm 2 , gas chromatograph method 50 cm 2.
Measurement time: 2 hours later (2) The results are shown in Table 1.
表１に示したように、実施例１で作製した組成物は優れた消臭性を有していることが確認された。 As shown in Table 1, it was confirmed that the composition produced in Example 1 had excellent deodorant properties.
＜実施例３＞組成物の抗菌性１
（１）実施例１で作製した組成物を綿に対して混合し、以下の条件で抗菌性を試験した。
<Example 3> Antibacterial property of composition 1
(1) The composition prepared in Example 1 was mixed with cotton and tested for antibacterial properties under the following conditions.
試験方法：ＪＳＬ１９０２：２００８定量試験（菌液吸収法）による。また、洗濯方法は、ＪＩＳ ０２１７ １０３号 の試験方法による。生菌数の測定方法は混釈平板培養法による。 Test method: According to JSL1902: 2008 quantitative test (bacterial solution absorption method). The washing method is based on the test method of JIS 0217 103. The viable cell count is measured by the pour plate culture method.
試験菌株：黄色ブドウ球菌 Staphylococcus Aureus ＮＢＲＣ １２７３２
（２）結果を表２に示す。
Test strain: Staphylococcus Aureus NBRC 12732
(2) The results are shown in Table 2.
表２に示したように、実施例１で作製した組成物は優れた抗菌性を有していることが確認された。 As shown in Table 2, it was confirmed that the composition prepared in Example 1 had excellent antibacterial properties.
さらに、上記（１）と同様の綿からなるソックスに実施例１で作製した組成物を練り込んだものについて、界面活性剤（Ｔｗｅｅｎ８０）０．０５％を添加した試験菌液を使用して、洗濯を繰り返し行い（０〜１０回）、抗菌性の変化を検討した。 Furthermore, for a sock made of the same cotton as in the above (1) and kneaded with the composition prepared in Example 1, using a test bacterial solution to which 0.05% of a surfactant (Tween 80) was added, Washing was repeated (0 to 10 times) to examine changes in antibacterial properties.
結果を表３に示す。 The results are shown in Table 3.
表３に示したように、実施例１で作製した組成物が練り込まれた綿ソックスは、洗濯を１０回繰り返しても抗菌性が大きく失われることはないことが確認された。 As shown in Table 3, it was confirmed that the cotton socks kneaded with the composition prepared in Example 1 did not lose their antibacterial properties significantly even after 10 times of washing.
＜実施例４＞組成物の抗菌性２
（１）綿に実施例１で作製した組成物を実用例１のもの、練り込み（具体的な方法について御教示下さい）、以下の条件で抗菌性を試験した。
<Example 4> Antibacterial property of composition 2
(1) The composition prepared in Example 1 was kneaded into cotton, kneaded (tell us about the specific method), and tested for antibacterial properties under the following conditions.
試験方法：ＪＳＬ１９０２：２００８定量試験（菌液吸収法）による。また、洗濯方法は、ＪＩＳ ０２１７ １０３号 の試験方法による。生菌数の測定方法は混釈平板培養法による。 Test method: According to JSL1902: 2008 quantitative test (bacterial solution absorption method). The washing method is based on the test method of JIS 0217 103. The viable cell count is measured by the pour plate culture method.
試験菌株：大腸菌 Ｅscherichia coli ＮＢＲＣ ３３０１
（２）結果を表４に示す。
Test strain: Escherichia coli NBRC 3301
(2) The results are shown in Table 4.
表４に示したように、実施例１で作製した組成物は優れた抗菌性を有していることが確認された。 As shown in Table 4, it was confirmed that the composition prepared in Example 1 had excellent antibacterial properties.
さらに、上記（１）と同様の綿からなるソックスに実施例１で作製した組成物を練り込んだものについて、界面活性剤（Ｔｗｅｅｎ８０）０．０５％を添加した試験菌液を使用して、洗濯を繰り返し行い（０〜１０回）、抗菌性の変化を検討した。 Furthermore, for a sock made of the same cotton as in the above (1) and kneaded with the composition prepared in Example 1, using a test bacterial solution to which 0.05% of a surfactant (Tween 80) was added, Washing was repeated (0 to 10 times) to examine changes in antibacterial properties.
結果を表５に示す。 The results are shown in Table 5.
表５に示したように、実施例１で作製した組成物が練り込まれた綿ソックスは、洗濯を１０回繰り返しても抗菌性が大きく失われることはないことが確認された。 As shown in Table 5, it was confirmed that the cotton socks kneaded with the composition prepared in Example 1 did not lose their antibacterial properties significantly even after 10 times of washing.
＜実施例５＞組成物の抗菌性３
（１）実施例３の試験の繊維を変更して同様の試験を行った。
<Example 5> Antibacterial property of composition 3
(1) The same test was performed by changing the fibers in the test of Example 3.
結果を表６に示す。 The results are shown in Table 6.
表６に示したように、実施例１で作製した組成物が練り込まれた繊維（洗濯０回）は、抗菌性が良好であることが確認された。一方、洗濯を１０回行った繊維では、種類によっては抗菌性の低下が確認された。 As shown in Table 6, it was confirmed that the fibers kneaded with the composition prepared in Example 1 (0 times of washing) had good antibacterial properties. On the other hand, it was confirmed that the fibers washed 10 times had a decreased antibacterial property depending on the type.
＜実施例６＞組成物の抗菌性４
（１）実施例４の試験の繊維を変更して同様の試験を行った。
<Example 6> Antibacterial property 4 of the composition
(1) The same test was performed by changing the fibers in the test of Example 4.
結果を表７に示す。 The results are shown in Table 7.
表７に示したように、実施例１で作製した組成物が練り込まれた繊維（洗濯０回）は、抗菌性が良好であることが確認された。一方、洗濯を１０回行った繊維では、種類によっては抗菌性の低下が確認された。 As shown in Table 7, it was confirmed that the fibers kneaded with the composition prepared in Example 1 (0 times of washing) had good antibacterial properties. On the other hand, it was confirmed that the fibers washed 10 times had a decreased antibacterial property depending on the type.
＜実施例７＞組成物の抗カビ性
（１）表が綿１００％であり、裏がポリエステル、ポリウレタンからなる繊維に実施例１で作製した組成物をリッピング加工（１／１００の重量比、６０℃で乾燥）したものについて、以下の条件で抗カビ性を試験した。
試験方法：約１８ｍｍ角の滅菌済み試料（０．２ｇ分）に、１／２０サブローデキストロース培地にて約１０５個／ｍｌに調整した胞子混濁液を０．２ｍｌ接種し、２５℃で４２時間培養した。培養後、試料上の胞子のＡＴＰ濃度を発光測定法にて測定した（試験胞子混濁液濃度：２．０×１０５個／ｍｌ）。
試験菌株：白癬菌 Trichophyton mentagrophytes NBRC 32409
結果を表８、表９に示す。
<Example 7> Antifungal property of composition (1) The composition prepared in Example 1 was rip-treated (weight ratio of 1/100, to a fiber whose surface was 100% cotton and whose back was polyester, polyurethane). Those dried at 60 ° C. were tested for antifungal properties under the following conditions.
Test method: About 18 mm square sterilized sample (0.2 g) was inoculated with 0.2 ml of spore suspension adjusted to about 105 cells / ml with 1/20 Sabouraud dextrose medium, and cultured at 25 ° C for 42 hours. did. After culturing, the ATP concentration of the spores on the sample was measured by a luminescence measurement method (test spore suspension concentration: 2.0 × 10 5 cells / ml).
Test strain: Trichophyton mentagrophytes NBRC 32409
The results are shown in Tables 8 and 9.
表８、表９に示したように、実施例１で作製した組成物は、５０倍、１００倍に希釈した場合も抗カビ性（抗菌性）を示すことが確認された。 As shown in Tables 8 and 9, it was confirmed that the composition prepared in Example 1 exhibited antifungal properties (antibacterial properties) even when diluted 50 times and 100 times.
＜実施例８＞組成物の抗ウイルス性
（１）靴下の繊維に実施例１で作製した組成物をリッピング加工（１／１００の重量比、６０℃で乾燥）したものについて、以下の条件で抗ウイルス性を試験した。
<Example 8> Antiviral property of composition (1) The composition produced in Example 1 was rip-processed on the fibers of socks (weight ratio of 1/100, dried at 60 ° C) under the following conditions. The antiviral properties were tested.
試験方法：ISO18184 Textiles-Determination of antivirial activity of textile productsによる。 Test method: ISO18184 Textiles-Determination of antivirial activity of textile products.
試験ウイルス：インフルエンザウイルス InfuenzaAvirus (H3N2) ：ATCC VR-1679
結果を表１０に示す。
Test virus: Influenza Avirus (H3N2): ATCC VR-1679
The results are shown in Table 10.
表１０に示したように、実施例１で作製した組成物（１００倍希釈）は、優れた抗ウイルス性を示すことが確認された。また、洗濯を１０回行った場合も組成物の脱落はほとんどなく、抗ウイルス性が維持されることが確認された。 As shown in Table 10, it was confirmed that the composition prepared in Example 1 (diluted 100 times) exhibited excellent antiviral properties. It was also confirmed that the composition did not drop even after washing 10 times and the antiviral property was maintained.
＜実施例９＞組成物の消臭性２
以下に示した条件１〜６の繊維に、実施例１で作製した組成物にグルタミン酸、クエン酸を加えたものをリッピング加工（１／１００の重量比、６０℃で乾燥）したものについて、以下の条件で消臭性を試験した。
１．表綿１００％
２．表綿１００％ 洗濯１０回後
３．表綿１００％ 洗濯３０回後
４．表綿 ６５％ ポリエステル３５％
５．表綿 ６５％ ポリエステル３５％ 洗濯１０回後
６．表綿 ６５％ ポリエステル３５％ 洗濯３０回後
試験方法：（一社）繊維評価技術評議会ＳＥＫマーク繊維製品認証基準２１．消臭試験（検知管法、ガスクロマトグラフ法）
ガス初発濃度：アンモニア１００ｐｐｍ、酢酸３０ｐｐｍ、イソ吉草酸３８ｐｐｍ
試験試料：検知管法１００ｃｍ２、ガスクロマトグラフ法５０ｃｍ２
測定時間：２時間後
洗濯処理方法：JIS L 0217 103法，１０、３０回繰り返し，吊えい干し
洗濯使用洗剤：ＪＡＦＥＴ標準配合洗剤使用
結果を表１１に示す。
<Example 9> Deodorant property 2 of composition
Fibers under the conditions 1 to 6 shown below were rip-processed by adding glutamic acid and citric acid to the composition prepared in Example 1 (weight ratio of 1/100, dried at 60 ° C.). The deodorizing property was tested under the conditions of.
1. 100% cotton
2. 100% of front cotton 10 times after washing 3. 100% of front cotton 30 times after washing 4. Surface cotton 65% Polyester 35%
5. Surface cotton 65% Polyester 35% After 10 washes 6. Surface cotton 65% Polyester 35% After 30 times of washing Test method: (1 company) Fiber Evaluation Technology Council SEK mark Textile product certification standard 21. Deodorization test (detection tube method, gas chromatograph method)
Gas initial concentration: Ammonia 100ppm, acetic acid 30ppm, isovaleric acid 38ppm
Test sample: Detector tube method 100 cm 2 , gas chromatograph method 50 cm 2.
Measurement time: After 2 hours Laundry treatment method: JIS L 0217 103 method, repeated 10 or 30 times, hanging and drying Laundry detergent: JAFET standard blended detergent used
The results are shown in Table 11.
表１１に示したように、条件１、４の結果から、実施例１で作製した組成物は優れた消臭性を有していることが確認された。また、条件２、３、５、６の結果から、洗濯を繰り返しても成分の脱落は生じ難く、消臭性が維持されることが確認された。 As shown in Table 11, it was confirmed from the results of Conditions 1 and 4 that the composition prepared in Example 1 had excellent deodorant properties. In addition, from the results of Conditions 2, 3, 5, and 6, it was confirmed that the components were less likely to drop off even after repeated washing, and the deodorant property was maintained.
＜実施例９＞抗菌・抗ウイルス性組成物の希釈時の成分割合
実施例１とは異なる以下の表１２に示した配合で、抗ウイルス性組成物を作製した。
<Example 9> Component ratio of the antibacterial / antiviral composition at the time of dilution An antiviral composition was prepared according to the formulation shown in Table 12 below, which was different from Example 1.
この抗菌・抗ウイルス性組成物は、実施例１で得た組成物と同等、またはそれ以上に抗ウイルス性、抗菌性、消臭性を示すことが確認された。 It was confirmed that this antibacterial / antiviral composition exhibits antiviral, antibacterial and deodorant properties equivalent to or higher than those of the composition obtained in Example 1.
また、表１２には、各成分の有効濃度の目安を示している。この濃度範囲であると抗ウイルス性、抗菌性、消臭性を確実に発揮することができる。 Table 12 shows the standard of effective concentration of each component. Within this concentration range, antiviral properties, antibacterial properties, and deodorant properties can be reliably exhibited.
なお、より好ましい配合割合としては、ピロリドンカルボン酸銀１０ｍｇ／Ｌ〜１００ｍｇ／Ｌ、ピロリドンカルボン酸亜鉛１１０ｍｇ／Ｌ〜５００ｍｇ／Ｌ、硫酸銅として１５０ｍｇ／Ｌ〜５００ｍｇ／Ｌ、グルタミン酸５ｍｇ／Ｌ〜２０ｍｇ／Ｌ、クエン酸１００ｍｇ／Ｌ〜１０００ｍｇ／Ｌ、Ｎ−長鎖アシルアミノ酸カリウム４００ｍｇ／Ｌ〜２０００ｍｇ／Ｌを例示することができる。 In addition, as a more preferable blending ratio, silver pyrrolidonecarboxylate 10 mg / L to 100 mg / L, zinc pyrrolidonecarboxylate 110 mg / L to 500 mg / L, copper sulfate 150 mg / L to 500 mg / L, glutamic acid 5 mg / L to 20 mg / L, citric acid 100 mg / L to 1000 mg / L, and N-long chain acylamino acid potassium 400 mg / L to 2000 mg / L can be exemplified.
Claims (5)
ピロリドンカルボン酸銀、ピロリドンカルボン酸亜鉛、ピロリドンカルボン酸銅およびＮ−長鎖アシルアミノ酸カリウムを含むことを特徴とする繊維用抗菌・抗ウイルス性組成物。 An antibacterial and antiviral composition for fibers having antibacterial and antiviral properties,
Pyrrolidone carboxylic acid silver, pyrrolidone carboxylic acid zinc, pyrrolidone carboxylic acid copper and N- long chain fibers for antibacterial and antiviral composition, characterized in that it comprises an acylamino acid potassium.
A fiber product, wherein the fiber is coated or impregnated with the antibacterial / antiviral composition for fibers according to any one of claims 1 to 4 .
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