JP6678231B2 - 皮膚バリア機能を改善するため、ならびに／または皮膚の老化を予防および／もしくは軽減するため、ならびに／または皮膚を保湿するのに使用するためのｕｃ．２９１の活性化因子 - Google Patents
皮膚バリア機能を改善するため、ならびに／または皮膚の老化を予防および／もしくは軽減するため、ならびに／または皮膚を保湿するのに使用するためのｕｃ．２９１の活性化因子 Download PDFInfo
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- FHHPUSMSKHSNKW-SMOYURAASA-M sodium deoxycholate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 FHHPUSMSKHSNKW-SMOYURAASA-M 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 230000004960 subcellular localization Effects 0.000 description 1
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- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000036572 transepidermal water loss Effects 0.000 description 1
- 239000012096 transfection reagent Substances 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
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- 230000000007 visual effect Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 239000004520 water soluble gel Substances 0.000 description 1
- 239000004552 water soluble powder Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
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- 239000008096 xylene Substances 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/148—Screening for cosmetic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15306219.5A EP3124620B1 (en) | 2015-07-27 | 2015-07-27 | Activators of uc.291 for use for improving skin barrier function and/or for preventing and/or attenuating skin ageing and/or for hydrating skin |
| EP15306219.5 | 2015-07-27 | ||
| PCT/EP2016/067784 WO2017017094A1 (en) | 2015-07-27 | 2016-07-26 | Activators of uc.291 for use for improving skin barrier function and/or for preventing and/or attenuating skin ageing and/or for hydrating skin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018526985A JP2018526985A (ja) | 2018-09-20 |
| JP2018526985A5 JP2018526985A5 (enExample) | 2018-11-01 |
| JP6678231B2 true JP6678231B2 (ja) | 2020-04-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018504233A Active JP6678231B2 (ja) | 2015-07-27 | 2016-07-26 | 皮膚バリア機能を改善するため、ならびに／または皮膚の老化を予防および／もしくは軽減するため、ならびに／または皮膚を保湿するのに使用するためのｕｃ．２９１の活性化因子 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20180216182A1 (enExample) |
| EP (1) | EP3124620B1 (enExample) |
| JP (1) | JP6678231B2 (enExample) |
| WO (1) | WO2017017094A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023069413A (ja) * | 2021-11-05 | 2023-05-18 | 花王株式会社 | 被膜の皮膚保湿効果の評価方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ299379A (en) * | 1995-10-27 | 1997-04-24 | Unilever Plc | Topical flavanone-containing composition |
| JP2005530708A (ja) | 2002-03-20 | 2005-10-13 | エナマニィ，ラスィド | フィトアレキシンの製造方法 |
| JP6043343B2 (ja) * | 2011-05-17 | 2016-12-14 | シャネル パフュームズ ビューテ | 皮膚の老化の予防および／もしくは低減ならびに／または皮膚を水和するためのｌａｒｇｅ、ｈｓ６ｓｔ２またはｓｔ８ｓｉａ１活性化剤 |
| FR2987371B1 (fr) * | 2012-02-24 | 2016-01-01 | Isp Investments Inc | Methode d'identification in vitro de composes modulateurs de la differenciation cellulaire par dosage du micro-arn mir-203 |
| JP6190105B2 (ja) * | 2012-11-13 | 2017-08-30 | 株式会社ナリス化粧品 | 皮膚バリア機能改善剤のスクリーニング方法 |
| US9981913B2 (en) * | 2013-09-04 | 2018-05-29 | Ralexar Therapeutics, Inc. | Liver X receptor (LXR) modulators |
-
2015
- 2015-07-27 EP EP15306219.5A patent/EP3124620B1/en active Active
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2016
- 2016-07-26 WO PCT/EP2016/067784 patent/WO2017017094A1/en not_active Ceased
- 2016-07-26 JP JP2018504233A patent/JP6678231B2/ja active Active
- 2016-07-26 US US15/747,458 patent/US20180216182A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017017094A1 (en) | 2017-02-02 |
| EP3124620A1 (en) | 2017-02-01 |
| US20180216182A1 (en) | 2018-08-02 |
| EP3124620B1 (en) | 2018-08-08 |
| JP2018526985A (ja) | 2018-09-20 |
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