JP6642935B2 - 眼投与用の半フッ素化化合物 - Google Patents

眼投与用の半フッ素化化合物 Download PDF

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JP6642935B2
JP6642935B2 JP2018515471A JP2018515471A JP6642935B2 JP 6642935 B2 JP6642935 B2 JP 6642935B2 JP 2018515471 A JP2018515471 A JP 2018515471A JP 2018515471 A JP2018515471 A JP 2018515471A JP 6642935 B2 JP6642935 B2 JP 6642935B2
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composition
compound
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composition according
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JP2018529693A (ja
JP2018529693A5 (https=
Inventor
シェラー，ディーター
グリレンベルガー，ラルフ
レッシャー，フランク
フォス，ハルトムート
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ノバリック ゲーエムベーハー
ノバリック ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/266—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of hydrocarbons and halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2018515471A 2015-09-30 2016-09-29 眼投与用の半フッ素化化合物 Active JP6642935B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15187760.2 2015-09-30
EP15187760 2015-09-30
EP15192429.7 2015-10-30
EP15192429 2015-10-30
PCT/EP2016/073262 WO2017055453A1 (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019240070A Division JP7050741B2 (ja) 2015-09-30 2019-12-30 眼投与用の半フッ素化化合物

Publications (3)

Publication Number Publication Date
JP2018529693A JP2018529693A (ja) 2018-10-11
JP2018529693A5 JP2018529693A5 (https=) 2019-12-19
JP6642935B2 true JP6642935B2 (ja) 2020-02-12

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Family Applications (2)

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JP2018515471A Active JP6642935B2 (ja) 2015-09-30 2016-09-29 眼投与用の半フッ素化化合物
JP2019240070A Active JP7050741B2 (ja) 2015-09-30 2019-12-30 眼投与用の半フッ素化化合物

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JP2019240070A Active JP7050741B2 (ja) 2015-09-30 2019-12-30 眼投与用の半フッ素化化合物

Country Status (14)

Country Link
US (2) US11154513B2 (https=)
EP (3) EP4234523A1 (https=)
JP (2) JP6642935B2 (https=)
KR (2) KR102584063B1 (https=)
CN (4) CN110693825B (https=)
AU (3) AU2016329261B2 (https=)
CA (1) CA2998269C (https=)
DE (1) DE202016008739U1 (https=)
DK (2) DK3356313T3 (https=)
ES (2) ES2953837T3 (https=)
MX (2) MX2018003781A (https=)
PL (2) PL3722274T3 (https=)
PT (1) PT3356313T (https=)
WO (1) WO2017055453A1 (https=)

Cited By (1)

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JP2020073551A (ja) * 2015-09-30 2020-05-14 ノバリック ゲーエムベーハー 眼投与用の半フッ素化化合物

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CN107397718A (zh) 2011-05-25 2017-11-28 诺瓦利克有限责任公司 基于半氟化烷烃类的外用药物组合物
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CN111182893A (zh) 2017-10-04 2020-05-19 诺瓦利克有限责任公司 包含f6h8的眼用组合物
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JP2021522219A (ja) 2018-04-27 2021-08-30 ノバリック ゲーエムベーハー 緑内障の治療のためのタフルプロストを含む眼科用組成物
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JP7050741B2 (ja) 2015-09-30 2022-04-08 ノバリック ゲーエムベーハー 眼投与用の半フッ素化化合物

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