JP6633098B2 - 歯牙美白方法 - Google Patents
歯牙美白方法 Download PDFInfo
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- JP6633098B2 JP6633098B2 JP2017555187A JP2017555187A JP6633098B2 JP 6633098 B2 JP6633098 B2 JP 6633098B2 JP 2017555187 A JP2017555187 A JP 2017555187A JP 2017555187 A JP2017555187 A JP 2017555187A JP 6633098 B2 JP6633098 B2 JP 6633098B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C19/00—Dental auxiliary appliances
- A61C19/06—Implements for therapeutic treatment
- A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
- A61C19/066—Bleaching devices; Whitening agent applicators for teeth, e.g. trays or strips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/08—Machine parts specially adapted for dentistry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/08—Machine parts specially adapted for dentistry
- A61C1/087—Supplying powder or medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C19/00—Dental auxiliary appliances
- A61C19/06—Implements for therapeutic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0204—Specific forms not provided for by any of groups A61K8/0208 - A61K8/14
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
- A61K2800/434—Luminescent, Fluorescent; Optical brighteners; Photosensitizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/83—Electrophoresis; Electrodes; Electrolytic phenomena
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Informatics (AREA)
- Cosmetics (AREA)
Description
図3は、トランスウェルメンブラン(transwell membrane)を用いて陰イオン照射による効果を確認する実験装置を示す模式図である。
歯牙美白用組成物として、過酸化水素を15重量%含む水溶液を準備した。図3に示されているようなトランスウェルメンブランの内部ウェルに前記組成物を100μM注入し、外部ウェルにはメチレンブルーを20ppmの濃度で含む水溶液450μMを注入した。
歯牙美白用組成物として、過酸化水素を15重量%、三リン酸カリウム(K3PO4)を12.5mM含む水溶液を準備したことを除けば、実施例1と同様の方法で陰イオン照射を実施した。
歯牙美白用組成物として、過酸化水素を15重量%、三リン酸カリウムを25mM含む水溶液を準備したことを除けば、実施例1と同様の方法で陰イオン照射を実施した。
歯牙美白用組成物として、過酸化水素を3重量%、三リン酸カリウムを25mM含む水溶液を準備したことを除けば、実施例1と同様の方法で陰イオン照射を実施した。
歯牙美白用組成物として、過酸化水素を7重量%、三リン酸カリウムを25mM含む水溶液を準備したことを除けば、実施例1と同様の方法で陰イオン照射を実施した。
実施例1と同様にトランスウェルメンブランを準備し、陰イオンを照射せずに常温で15分間放置した。
実施例3と同様にトランスウェルメンブランを準備し、陰イオンを照射せずに常温で15分間放置した。
実施例4と同様にトランスウェルメンブランを準備し、陰イオンを照射せずに常温で15分間放置した。
実施例5と同様にトランスウェルメンブランを準備し、陰イオンを照射せずに常温で15分間放置した。
歯牙美白用組成物として、過酸化水素を15重量%、プロピレングリコールを25mM含む水溶液を調製したことを除けば、実施例1と同様の方法で陰イオン照射を実施した。
1)陰イオン照射による浸透度の評価
陰イオンの照射による過酸化水素の歯牙への浸透度を評価するために、過酸化水素を15重量%、三リン酸カリウムを25mM含む組成物を準備した。図3に示されているようなトランスウェルメンブランの内部ウェルに前記組成物を200μM注入し、外部ウェルには水溶液700μMを注入した。
前記表1および図4を参照して、実施例1、3、4、5および比較例1、2、3、4をそれぞれ比較すると、同一の組成の美白用組成物に対して、陰イオンを照射する場合と、照射しなかった場合とで、メチレンブルーの分解度が最小約2.8倍から最大約7倍まで増加した。
実施例1〜3を比較すると、電解質として三リン酸カリウムを含むことによって、同一の条件においてメチレンブルーの分解度が上昇することが分かり、このような分解度の上昇効果は、三リン酸カリウムの濃度に少なくとも25mMまでは比例することが明らかになった。
Claims (6)
- 過酸化物を含む歯牙美白用組成物を歯牙に塗布する工程と、
前記歯牙美白用組成物に陰イオンを照射する工程とを含む、歯牙美白方法。 - 前記歯牙美白用組成物は、電解質をさらに含む、請求項1に記載の歯牙美白方法。
- 前記電解質は、リン酸カリウム類(K3PO4、K2HPO4、KH2PO4)、塩化ナトリウム(NaCl)、硫酸(H2SO4)、塩酸(HCl)、水酸化ナトリウム(NaOH)、水酸化カリウム(KOH)、および硝酸ナトリウム(Na2NO3)からなる群より選択される1種以上を含む、請求項2に記載の歯牙美白方法。
- 前記歯牙美白用組成物における前記電解質の濃度は、1〜100mMである、請求項2に記載の歯牙美白方法。
- 前記過酸化物は、過酸化水素、過ホウ酸塩、過炭酸塩、過リン酸塩、過硫酸塩類、過酸化カルシウム、過酸化マグネシウム、および過酸化尿素からなる群より選択される1種以上を含む、請求項1に記載の歯牙美白方法。
- 前記歯牙美白用組成物は、全体重量に対して1〜35重量%の前記過酸化物を含む、請求項1に記載の歯牙美白方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2015-0003496 | 2015-01-09 | ||
KR1020150003496A KR101536272B1 (ko) | 2015-01-09 | 2015-01-09 | 치아 미백 방법 |
PCT/KR2016/000098 WO2016111544A1 (ko) | 2015-01-09 | 2016-01-06 | 치아 미백 방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018502153A JP2018502153A (ja) | 2018-01-25 |
JP6633098B2 true JP6633098B2 (ja) | 2020-01-22 |
Family
ID=53793099
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Application Number | Title | Priority Date | Filing Date |
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JP2017555187A Expired - Fee Related JP6633098B2 (ja) | 2015-01-09 | 2016-01-06 | 歯牙美白方法 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10172769B2 (ja) |
EP (1) | EP3243483B1 (ja) |
JP (1) | JP6633098B2 (ja) |
KR (1) | KR101536272B1 (ja) |
CN (1) | CN107205806A (ja) |
WO (1) | WO2016111544A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101536272B1 (ko) * | 2015-01-09 | 2015-07-13 | 주식회사 덴트화이트 | 치아 미백 방법 |
CN111214307A (zh) * | 2020-01-18 | 2020-06-02 | 陈敬 | 一种护齿美白牙套及其制作方法和使用方法 |
CN112156028A (zh) * | 2020-10-28 | 2021-01-01 | 上海交通大学医学院附属第九人民医院 | 一种新型牙齿美白凝胶及其制备方法和应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU660691B2 (en) * | 1991-09-13 | 1995-07-06 | Colgate-Palmolive Company, The | Abrasive tooth whitening dentifrice of improved stability |
US5785527A (en) * | 1997-01-10 | 1998-07-28 | Ultradent Products, Inc. | Stable light or heat activated dental bleaching compositions |
JP2003159305A (ja) * | 2001-09-13 | 2003-06-03 | Matsushita Electric Works Ltd | 肌ケア装置 |
FR2844719B1 (fr) * | 2002-09-24 | 2004-11-19 | Francois Duret | Dispositif electro-chimique pour le blanchiment d'un corps |
US20050008584A1 (en) * | 2003-05-16 | 2005-01-13 | Britesmile Development, Inc. | Therapeutic dental composition |
US7775795B2 (en) * | 2003-12-29 | 2010-08-17 | Fluorinex Active Ltd. | Electrochemically treating teeth |
US20080075676A1 (en) * | 2004-11-09 | 2008-03-27 | Discus Dental, Llc | Dental Whitening Systems |
KR100657127B1 (ko) * | 2004-11-29 | 2006-12-12 | 주식회사 엘지생활건강 | 용시 겔화를 이용한 치아 미백 성분 전달 시스템 |
CN201015606Y (zh) * | 2006-08-14 | 2008-02-06 | 郭安玉 | 一种牙齿美白装置 |
US20090081136A1 (en) * | 2007-09-24 | 2009-03-26 | Deepak Sharma | Compositions Useful For Tooth Whitening |
CN201404306Y (zh) * | 2009-05-22 | 2010-02-17 | 天津滨海华医光电技术有限公司 | 激光牙齿美白装置 |
JP4936202B2 (ja) * | 2009-12-07 | 2012-05-23 | パナソニック株式会社 | イオン発生装置 |
WO2011133793A2 (en) * | 2010-04-21 | 2011-10-27 | Discus Dental, Llc | Method of simultaneously cleaning and whitening teeth |
WO2011146978A1 (en) | 2010-05-25 | 2011-12-01 | International Scientific Pty Ltd | Delivery of oral care products |
KR101474490B1 (ko) * | 2012-10-29 | 2015-01-14 | 주식회사 올인원바이오 | 치아 미백제 및 이를 이용한 치아 미백 장치 |
US9320580B2 (en) * | 2013-04-21 | 2016-04-26 | Oraceutical Llc | Hand-held tooth whitening instrument with applicator reservoir for whitening composition and methods of using same |
KR101536272B1 (ko) * | 2015-01-09 | 2015-07-13 | 주식회사 덴트화이트 | 치아 미백 방법 |
-
2015
- 2015-01-09 KR KR1020150003496A patent/KR101536272B1/ko active IP Right Grant
-
2016
- 2016-01-06 JP JP2017555187A patent/JP6633098B2/ja not_active Expired - Fee Related
- 2016-01-06 EP EP16735165.9A patent/EP3243483B1/en active Active
- 2016-01-06 WO PCT/KR2016/000098 patent/WO2016111544A1/ko active Application Filing
- 2016-01-06 US US15/538,250 patent/US10172769B2/en not_active Expired - Fee Related
- 2016-01-06 CN CN201680005221.5A patent/CN107205806A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3243483A4 (en) | 2018-01-10 |
CN107205806A (zh) | 2017-09-26 |
US10172769B2 (en) | 2019-01-08 |
WO2016111544A8 (ko) | 2017-03-09 |
KR101536272B1 (ko) | 2015-07-13 |
EP3243483B1 (en) | 2019-02-20 |
WO2016111544A1 (ko) | 2016-07-14 |
JP2018502153A (ja) | 2018-01-25 |
US20170367942A1 (en) | 2017-12-28 |
EP3243483A1 (en) | 2017-11-15 |
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