JP6618892B2 - 細菌バイオフィルムの遺伝的リプログラミング - Google Patents

細菌バイオフィルムの遺伝的リプログラミング Download PDF

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Publication number
JP6618892B2
JP6618892B2 JP2016510750A JP2016510750A JP6618892B2 JP 6618892 B2 JP6618892 B2 JP 6618892B2 JP 2016510750 A JP2016510750 A JP 2016510750A JP 2016510750 A JP2016510750 A JP 2016510750A JP 6618892 B2 JP6618892 B2 JP 6618892B2
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csga
biofilm
curli
polypeptide
modified
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JP2016526013A5 (enExample
JP2016526013A (ja
Inventor
ニール サティシュ ジョシ、
ニール サティシュ ジョシ、
ピーター クオック グエン、
ピーター クオック グエン、
ソフィア ボトヤンツキ、
ソフィア ボトヤンツキ、
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Harvard University
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Harvard University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Water Treatment By Sorption (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
JP2016510750A 2013-04-23 2014-04-23 細菌バイオフィルムの遺伝的リプログラミング Active JP6618892B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361814908P 2013-04-23 2013-04-23
US61/814,908 2013-04-23
PCT/US2014/035095 WO2014176311A1 (en) 2013-04-23 2014-04-23 Genetic reprogramming of bacterial biofilms

Related Child Applications (1)

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JP2018166085A Division JP2019022491A (ja) 2013-04-23 2018-09-05 細菌バイオフィルムの遺伝的リプログラミング

Publications (3)

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JP2016526013A JP2016526013A (ja) 2016-09-01
JP2016526013A5 JP2016526013A5 (enExample) 2017-06-15
JP6618892B2 true JP6618892B2 (ja) 2019-12-11

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JP2016510750A Active JP6618892B2 (ja) 2013-04-23 2014-04-23 細菌バイオフィルムの遺伝的リプログラミング
JP2018166085A Pending JP2019022491A (ja) 2013-04-23 2018-09-05 細菌バイオフィルムの遺伝的リプログラミング

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US (3) US9815871B2 (enExample)
EP (1) EP2989122B1 (enExample)
JP (2) JP6618892B2 (enExample)
WO (1) WO2014176311A1 (enExample)

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JP6618892B2 (ja) 2013-04-23 2019-12-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 細菌バイオフィルムの遺伝的リプログラミング
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US20160185828A1 (en) 2016-06-30
US20200255480A1 (en) 2020-08-13
JP2019022491A (ja) 2019-02-14
US10550160B2 (en) 2020-02-04
US20180186840A1 (en) 2018-07-05
EP2989122B1 (en) 2019-04-03
WO2014176311A1 (en) 2014-10-30
EP2989122A1 (en) 2016-03-02
US11352397B2 (en) 2022-06-07
US9815871B2 (en) 2017-11-14
EP2989122A4 (en) 2016-10-26
JP2016526013A (ja) 2016-09-01

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