JP6566868B2 - 軽度および中等度アルツハイマー病の処置 - Google Patents

軽度および中等度アルツハイマー病の処置 Download PDF

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JP6566868B2
JP6566868B2 JP2015535750A JP2015535750A JP6566868B2 JP 6566868 B2 JP6566868 B2 JP 6566868B2 JP 2015535750 A JP2015535750 A JP 2015535750A JP 2015535750 A JP2015535750 A JP 2015535750A JP 6566868 B2 JP6566868 B2 JP 6566868B2
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JP2015535850A (ja
JP2015535850A5 (enExample
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オルランディ,チェーザレ
クラーク,デヴィッド・ジェイ
グライムズ,イモジェン・エム
バルカルセ・ロペス,マリア・カルメン
コステュラ,マシュー・ジェイ
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ブイティーブイ・セラピューティクス・エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
JP2015535750A 2012-10-05 2013-10-02 軽度および中等度アルツハイマー病の処置 Active JP6566868B2 (ja)

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US201261710229P 2012-10-05 2012-10-05
US61/710,229 2012-10-05
PCT/US2013/062964 WO2014055588A1 (en) 2012-10-05 2013-10-02 Treatment of mild and moderate alzheimer's disease

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EP (1) EP2903606A1 (enExample)
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KR (1) KR20150064743A (enExample)
CN (2) CN104703592A (enExample)
AU (2) AU2013327450B2 (enExample)
BR (1) BR112015007641A8 (enExample)
CA (1) CA2886785C (enExample)
EA (1) EA201590687A1 (enExample)
HK (1) HK1207004A1 (enExample)
IL (1) IL237730B (enExample)
IN (1) IN2015DN03734A (enExample)
MX (1) MX377733B (enExample)
NZ (2) NZ705813A (enExample)
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JP7464591B2 (ja) 2018-10-10 2024-04-09 ブイティーブイ・セラピューティクス・エルエルシー [3-(4-{2-ブチル-1-[4-(4-クロロ-フェノキシ)-フェニル]-1h-イミダゾール-4-イル}-フェノキシ)-プロピル]-ジエチル-アミンの代謝産物
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US11648235B1 (en) 2022-12-30 2023-05-16 Cantex Pharmaceuticals, Inc. Treatment of glioblastoma

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US20170326113A1 (en) 2017-11-16
CN104703592A (zh) 2015-06-10
CA2886785C (en) 2022-06-07
MX2015003732A (es) 2015-09-23
MX377733B (es) 2025-03-11
JP2015535850A (ja) 2015-12-17
BR112015007641A8 (pt) 2018-04-03
CA2886785A1 (en) 2014-04-10
AU2013327450B2 (en) 2018-07-12
IN2015DN03734A (enExample) 2015-09-18
JP6894940B2 (ja) 2021-06-30
EP2903606A1 (en) 2015-08-12
BR112015007641A2 (pt) 2017-07-04
US20140100218A1 (en) 2014-04-10
US20190142803A1 (en) 2019-05-16
WO2014055588A1 (en) 2014-04-10
JP2019163301A (ja) 2019-09-26
AU2018203434A1 (en) 2018-06-07
CN110292638A (zh) 2019-10-01
KR20150064743A (ko) 2015-06-11
NZ739521A (en) 2019-06-28
AU2013327450A1 (en) 2015-05-14
NZ705813A (en) 2018-02-23
IL237730B (en) 2018-10-31
EA201590687A1 (ru) 2015-09-30
US9717710B2 (en) 2017-08-01
HK1207004A1 (en) 2016-01-22
SG11201502210VA (en) 2015-04-29
SG10201702648YA (en) 2017-04-27

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