JP6519844B2 - Water-in-oil emulsion composition - Google Patents

Description

  The present invention relates to a water-in-oil type skin external composition, and more particularly to a water-in-oil type emulsion composition in which two or more kinds of water phases different in composition exist in an oil phase.

  The water-in-oil emulsion composition has a high blocking effect due to the presence of the oil component in the continuous phase, and has advantages such as high moisture retention. Attempts have been proposed to improve the percutaneous absorbability of a water-soluble active ingredient while being in the form of a water-in-oil emulsifier by incorporating vesicles in such a water-in-oil emulsion composition (for example, patent documents 1).

  Moreover, in the water-in-oil type emulsion composition, a technique is proposed in which two types of water-soluble active ingredients are stably contained (see, for example, Patent Document 2).

JP 2007-308380 A JP, 2013-216640, A

When the present inventors examined, the preparation described in Patent Document 2 had room for improvement in stability over time. Therefore, in the present invention, it is an object of the present invention to provide a water-in-oil emulsion composition, in particular a (W1 + W2) / O emulsion composition, whose stability over time is improved.
In the present specification, W represents an aqueous phase, W1 and W2 each represent an aqueous phase having a different composition, and O represents an oil phase.

  The inventors of the present invention have made researches to solve the above problems, and have conceived that a water-in-oil emulsion composition having improved stability over time can be obtained by forming an emulsion by phase D emulsification. Completed.

The present invention is a water-in-oil emulsion composition in which the aqueous phase is covered with a D phase film. Further, the water-in-oil type emulsified composition of the present invention is an emulsion formed by D-phase emulsification. The water-in-oil type emulsified composition of the present invention is at least one selected from polyhydric alcohol fatty acid esters, silicone surfactants, cationic surfactants, amphoteric surfactants, and anionic surfactants. It is preferable to contain The water-in-oil emulsion composition of the present invention preferably contains a polyhydric alcohol. Furthermore, the water-in-oil emulsion composition of the present invention preferably contains two or more aqueous phases having different compositions. The water-in-oil emulsion composition of the present invention is preferably a skin external preparation, more preferably a cosmetic.
In the present specification, HLB (Hydrophilic-Lypophilic Balance) refers to a value calculated by the formula of glyphin.

  According to the present invention, there is provided a water-in-oil emulsion composition having improved stability over time. In the emulsion composition of the present invention, the aqueous phase is covered with a highly elastic D-phase film, and such an aqueous phase does not unite even when a shear force or the like is applied, so the emulsifier of the present invention has a high temperature. It is stable over time under the conditions.

A LSM observation photograph (magnification of 400 times) of a (W1 + W2) / O type emulsion composition of Example 1.

  Hereinafter, although the water-in-oil type emulsion composition of this invention is demonstrated, the technical scope of this invention is not limited only to the following specific embodiments.

The emulsion composition of the present invention is a water-in-oil emulsion composition in which the water phase is covered with a D phase film.
Phase D is also usually referred to as middle phase microemulsion phase, bicontinuous phase, sponge phase, surfactant phase, bicontinuous microemulsion phase, and the like. In the D phase, the number of association of surfactant molecules is significantly increased to lower the interfacial tension between the oil phase and the water phase to form a continuous phase, whereby efficient emulsification is performed. In addition, D phase differs from the liquid crystal phase disclosed by Unexamined-Japanese-Patent 2004-010549, 2010-67049 grade | etc.,.
In the emulsion composition of the present invention, since the D phase film covering the aqueous phase has high elasticity, the aqueous phase does not coalesce even if a shear force or the like is applied. As a result, the emulsified composition of the present invention is stable over time even under high temperature conditions.

The water-in-oil type emulsifier may be a general W / O type, but in the present invention, it is a water-in-oil type emulsifier containing two or more kinds of water phases different in composition. May be For example, an emulsion composition having two aqueous phases (W1 and W2) different in composition, such as (W1 + W2) / O emulsion type, can be mentioned. Of course, it may be an embodiment having three aqueous phases (W1, W2 and W3) different in composition.
By having two or more types of aqueous phases different in composition, the environmental conditions of the aqueous phase can be made different from each other, so that the optimum environment of each active ingredient to be included in the aqueous phase can be prepared.
In addition, as described above, the water-in-oil emulsion composition of the present invention is excellent in temporal stability, and two or more aqueous phases can be stably present in the composition without coalescence, An environment suitable for each active ingredient can be maintained.

Methods of preparing W / O-type emulsified compositions are widely known in the art.
As a method of preparing the (W1 + W2) / O emulsion composition, for example, as disclosed in Patent Document 2,
1) After preparing W1 / O emulsion composition, adding W2 to prepare (W1 + W2) / O emulsion composition, and 2) adjusting W1 / O emulsion composition and W2 / O emulsion composition respectively And mixing to prepare a (W1 + W2) / O emulsion composition.

The emulsion composition of the present invention can be prepared by forming an emulsion via phase D (D-phase emulsification) when preparing the emulsion composition by the above-mentioned method or the like.
The passage through the D phase can be confirmed by the fact that the system has a transparent or translucent appearance during the preparation process, and becomes a one-phase solution in which all the components to be blended are uniformly dissolved.
In the emulsion formed by D phase emulsification, the emulsion droplets (water phase) are covered with the D phase film, and the emulsion droplet particles are very small. Usually, the particle diameter of the emulsion droplet is 0.01 μm or more and 5 μm or less, preferably 2 μm or less, more preferably 1 μm or less, and still more preferably 0.5 μm or less.

Usually, polyhydric alcohols are used to perform D-phase emulsification.
Examples of polyhydric alcohols used in the emulsion composition of the present invention include polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene glycol, dipropylene glycol, diglycerin, isoprene glycol, Preferred are 1,2-pentanediol, 2,4-hexylene glycol, 1,2-hexanediol, 1,2-octanediol and the like. Among these, polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, multilol and diglycerin are more preferable, and glycerin is particularly preferable.
The polyhydric alcohol may be used alone or in combination of two or more, and the total content thereof is preferably 1 to 50% by weight, more preferably 5 to 40% by weight, and more preferably 10 to 30% by weight based on the total weight of the emulsion composition. Is more preferred.

Usually, a surfactant is used to perform D-phase emulsification.
Surfactants include fatty acid soaps (sodium laurate, sodium palmitate, etc.), anionic surfactants such as potassium lauryl sulfate, triethanolamine ether alkyl sulfate, stearyltrimethylammonium chloride, benzalkonium chloride, laurylamine Cationic surfactants such as oxides,
Betaine surfactants (alkylbetaine, amidobetaine, sulfobetaine, etc.), imidazoline amphoteric surfactants (2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxydisodium salt, etc.), acyl methyl taurine Amphoteric surfactants such as
Polyethylene glycol fatty acid esters (polyethylene glycol monooleate, polyethylene glycol monostearate, polyethylene glycol monolaurate, etc.), sorbitan fatty acid esters (sorbitan monooleate, sorbitan monostearate, sorbitan monoisostearate, sorbitan monolaurate, sesquiolein Sorbitan acid etc., monoglycerin fatty acids (glyceryl laurate, glyceryl myristate, glyceryl stearate, glyceryl behenate, glyceryl oleate, glyceryl isostearate, palm oil fatty acid glycerin, hardened beef tallow oil fatty acid glycerin, lanolinic acid glycerin etc , Polyglycerin fatty acids (diglyceryl stearate, diglyceryl oleate, distearic acid isostearate) Glyceryl, tetraglyceryl stearate, tetraglyceryl oleate, hexaglyceryl laurate, etc., propylene glycol fatty acid esters (such as propylene glycol monostearate), hydrogenated castor oil derivatives, glycerin alkyl ether, POE sorbitan fatty acid Esters (Polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan tristearate, Triisostearic acid polyoxyethylene sorbitan etc.), POE sorbite fatty acid esters (POE-sorbic) Monolaurate etc., POE glycerine fatty acid esters (polyoxyethylene glyceryl monomyristate, polyoxyethylene glyceryl monostearate, polyoxyethylene glyceryl monoisostearate, polyoxyethylene glyceryl triisostearate etc), POE fatty acid esters (POE monooleate, POE distearate etc.) POE alkyl ethers (polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene behenyl ether, polyoxyethylene oleyl ether, polyoxyethylene hexyl decyl ether , Polyoxyethylene isostearyl ether, polyoxyethylene octyldodecyl ether, polyoxy Tylene decyl pentadecyl ether, polyoxyethylene decyl tetradecyl ether, polyoxyethylene cholesteryl ether, polyoxyethylene nonyl phenyl ether, polyoxyethylene octyl phenyl ether, polyoxyethylene polyoxypropylene cetyl ether, polyoxyethylene polyoxypropylene decyl Tetradecyl ether etc., POE alkylphenyl ethers (POE nonyl phenyl ether etc.), polyoxyethylene fatty acid amides (lauric acid diethanolamide, coconut oil fatty acid diethanolamide, polyoxyethylene stearic acid amide etc.), pluronic types, POE・ POP alkyl ethers (POE, POP 2-decyl tetradecyl ether etc.), tetronics, POE castors・ Cured castor oil derivative (POE castor oil, POE hydrogenated castor oil etc.), sucrose fatty acid ester, alkyl glucoside, polyoxyethylene sorbite beeswax, polyoxyethylene lanolin, polyoxyethylene lanolin alcohol, polyoxyethylene sorbitol lanolin, dimethyl lauryl Nonionic surfactants such as amine oxide,
Silicone surfactants such as PEG-10 dimethicone, PEG / PPG-20 / 20 dimethicone, polysilicone-13, lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone, etc. are mentioned, and among these, the D phase emulsification efficiency is effective From the viewpoint of frequent use, silicone surfactants are more preferable, and polyether modified silicone surfactants are more preferable.

Further, among them, from the viewpoint of efficiently performing D-phase emulsification, one having HLB (Hydrophilic-Lypophilic Balance) of 3 or more and 8 or less is preferable, and 4 or more and 6 or less is more preferable. Conventionally, there has been an example in which an O / W emulsifier was produced using D-phase emulsification, but it was sometimes difficult to produce a W / O emulsifier using D-phase emulsification. This is considered to be due to the fact that surfactant molecules to be adsorbed at the oil-water interface tend to be monodispersed in the oil phase, since W / O emulsifiers are generally soluble in oil solutions. The present inventor has conceived that if the above-described surfactant is used, D-phase emulsification can be efficiently performed even in the production of a W / O emulsifier.
The surfactant may be used alone or in combination of two or more, and the total content thereof is preferably 0.1 to 20% by weight, more preferably 1 to 10% by weight, based on the total weight of the emulsion composition, 3 to 6 Weight percent is more preferred.

The water-in-oil emulsion composition of the present invention can be suitably used for skin external preparations, and can be applied to cosmetics, quasi-drugs, and pharmaceuticals, and is appropriately required depending on the respective uses. Ingredients can be included. Among these, it is preferable to apply to cosmetics, especially skin care cosmetics.
When applied to cosmetics, it is possible to widely mix the components that are usually used in cosmetics, and there is no limitation on the dosage form or application. Hereinafter, when it applies to cosmetics, the component which can be contained in cosmetics is demonstrated.
Examples of components that are usually used in cosmetics include various active ingredients, oil components, thickeners, powders, UV absorbers, organically modified clay minerals and the like.
Examples of the active ingredient include a whitening ingredient, a wrinkle improving ingredient, an anti-inflammatory ingredient, extracts derived from animals and plants, and the like. An active ingredient may contain only 1 type, and 2 or more types may be contained.

The light-whitening component is not particularly limited as long as it is generally used in cosmetics, and examples thereof include 4-n-butyl resorcinol, ascorbic acid glucoside, 3-O-ethyl ascorbic acid, tranexamic acid, arbutin, 1-triphenylmethylpiperidine, 1-triphenylmethylpyrrolidine, 2- (triphenylmethyloxy) ethanol, 2- (triphenylmethylamino) ethanol, 2- (triphenylmethyloxy) ethylamine, triphenylmethylamine, tri Phenylmethanol, triphenylmethane and aminodiphenylmethane, N- (p-toluyl) cysteic acid, N- (p-methoxybenzoyl) cysteic acid, N-benzoyl-serine, N- (p-methylbenzoyl) serine, N- ( p-ethyl benzoyl) serine N- (p-methoxybenzoyl) serine, N- (p-fluorobenzoyl) serine, N- (p-trifluoromethylbenzoyl) serine, N- (2-naphthoyl) serine, N- (p-methylbenzoyl)- O-methylserine, N- (p-methylbenzoyl) -O-acetylserine, N- (2-naphthoyl) -O-methylserine, kojic acid, 4-methoxysalicylic acid potassium salt, camomira extract, melissa extract, artichoke extract, yuzu extract And mayorana extract, loquat leaf extract, cuckon extract, aloe extract, chlorella extract and the like.
The content of the whitening component in the cosmetic is usually 0.01 to 10% by mass, preferably 0.1 to 10% by mass, and more preferably 0.2 to 5% by mass.

  The wrinkle improving component is not particularly limited as long as it is generally used in cosmetics. For example, vitamin A or a derivative thereof may be retinol, retinal, retinoic acid, tretinoin, isotretinoin, tocopherol retinoic acid, retinol palmitate, retinol acetate, benzyl alcohol ursolic acid, ursolic acid benzyl ester, phosphoric acid ursolic acid ester, betulinic acid benzyl ester, benzyl acid Examples thereof include phosphoric acid ester, sodium chondroitin sulfate, 2-methacryloyloxyethyl phosphoryl choline, cerebricum extract, mothberry leaf extract, hydrolysed bilberry root carrot extract, cornflower extract and the like. The content of the wrinkle improving component in the cosmetic is usually 0.01 to 10% by mass, preferably 0.1 to 10% by mass, and more preferably 0.2 to 5% by mass.

The extracts derived from animals and plants are not particularly limited as long as they are generally used for pharmaceuticals, cosmetics, foods and the like. For example, akebi extract, asunaro extract, asparagus extract, avocado extract, amacha extract, almond extract, arnica extract, aloe extract, alonia extract, apricot extract, ginkgo extract, indinoquino extract, fennel extract, udo extract, ginseng extract , Amelanchoa extract, aubergine extract, aubergium extract, auula extract, aubergine extract, aubergium extract, aubergium extract, aubergium extract, orange extract, akakoshi extract, a cuckoo extract, a kamomi extract, a carrot extract, a persimmon extract, a licorice extract, a kiwi extract, a cucumber extract, Guava extract, Kujin extract, Gardenia extract, Kumazasa extract, Clara extract, Walnut extract, Grapefruit extract, Black rice extract Sesame, Chlorella extract, Mulberry extract, Keiketsou extract, Gentiana extract, Gentian extract, Genno Shoko extract, black tea extract, burdock extract, rice extract, rice fermented extract, rice bran fermented extract, rice germ oil, rice germ oil, cowberry extract, salvia extract, sapon extract Sasa extract, hawthorn extract, sancha extract, sansho extract, shiitake extract, diorium extract, shikon extract, shiso extract, linden extract, persimmon extract, persimmon extract, persimmon extract, persimmon root extract, persimmon root extract, persimmon extract, stevia extract, stevia fermented , Azalea extract, Azalea extract, Azalea extract, Azalea extract, Azalea extract, Sage extract, Xenia extract Kiss, senkyu extract, seembry extract, souhakuhi extract, soya bean extract, soy bean extract, soya root extract, thyme extract, thyme extract, dandelion extract, tea extract, chopstick extract, chimpanzee extract, persimmon tea extract, red pepper extract, toucan extract, toucan senka extract, tounin extract , Dokudami extract, tomato extract, natto extract, carrot extract, garlic extract, Novara extract, Hibiscus extract, baconedou extract, lotus extract, lotus extract, parsley extract, birch extract, Hamameris extract, Hikiokoshi extract, Hinoki extract, loquat extract, Fukinohida extract, , Buchsia extract, butcherbroom extract, grape extract, grape seed extract, pomace extract, safflower extract, peppermint extract, Daisy extract, Button extract, Hop extract, Pine extract, Mayonara extract, Marubeni extract, Mukuroshi extract, Melissa extract, Mozuku extract, Peach extract, Pomegranate extract, Eucalypt extract, Eucalyptus extract, Yukinoshita extract, Yuzu extract, Licorice extract, Yokuinin extract, Yomogi extract, Lavender Extracts such as green tea extract, apple extract, rooibos tea extract, lice extract, lettuce extract, lemon extract, forsythia extract, rosewood extract, rose extract, rosemary extract, rose chamomile extract, royal jelly extract, waremow extract It can be mentioned.
The content of the animal and plant derived extract in the cosmetic is usually 0.01 to 10% by mass, preferably 0.1 to 10% by mass, and more preferably 0.2 to 5% by mass.

Examples of the anti-inflammatory component include clarinone, glabridin, glycyrrhizinic acid, glycyrrhetinic acid and the like, preferably glycyrrhizinic acid and a salt thereof, alkyl glycyrrhetinate and a salt thereof, and glycyrrhetinic acid and a salt thereof.
The content of the anti-inflammatory component in the cosmetic is usually 0.01 to 10% by mass, preferably 0.1 to 5% by mass, and more preferably 0.2 to 3% by mass.

Examples of oily components include polar oils, natural oils, hydrocarbon oils, silicone oils and the like.
As polar oils, as synthetic ester oils, isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyl dimethyl octanoate, lactic acid Cetyl, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, ethylene glycol di-2-ethylhexylate, dipentaerythritol fatty acid ester, N-alkyl glycol monoisostearate, neopentyl dicaprate Glycol, diisostearyl malate, glycerin di-2-heptylundecanoate, trimethylolpropane tri-2-ethylhexylate May be mentioned trimethylolpropane triisostearate, tetra-2-ethylhexyl acid pentane erythritol, tri-2-ethylhexyl acid glycerin, trimethylolpropane triisostearate.

  Furthermore, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glycerin trimyristate, glyceride tri-2-heptylundecanoate, castor oil fatty acid methyl ester, oleic acid oil, cetostearyl alcohol, acetoglyceride, palmitic acid 2 -Heptylundecyl, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di-2-heptylundecyl adipate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyl myristate Decyl, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, ethyl acetate, butyl acetate, amyl acetate, triethyl citrate, octyl acetate Kishishin'nameto, etc. may also be mentioned.

  In addition, as natural oil, avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil, castor oil, linseed oil, Safflower oil, cotton seed oil, eno oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, Japanese oak oil, Japanese tung oil, jojoba oil, germ oil, triglycerin, glycerin trioctanoate, glycerin triisopalmitate Etc.

Examples of hydrocarbon oils include isododecane, isohexadecane, squalane, vaseline, hydrogenated poly (C6-12 olefin), hydrogenated polyisobutene and the like, among which vaseline is preferred.
Examples of silicone oils include cyclopentasiloxane, decamethylcyclopentasiloxane, caprylyl methicone, dimethicone, (dimethicone / vinyl dimethicone) crosspolymer, (dimethicone / phenyl vinyl dimethicone) crosspolymer, etc. Highly polymerized dimethicone having a viscosity of 10,000 mPas is preferred.

As a thickener, guar gum, quince seed, carrageenan, galactan, gum arabic, pectin, mannan, starch, xanthan gum, curdlan, methyl cellulose, hydroxyethyl cellulose, carboxymethyl cellulose, methyl hydroxypropyl cellulose, chondroitin sulfate, dermatan sulfate, glycogen, Heparan sulfate, hyaluronic acid, sodium hyaluronate, tragant gum, keratan sulfate, chondroitin sulfate, mucoitin sulfate, hydroxyethyl guar gum, carboxymethyl guar gum, dextran, kerato sulfate, locust bean gum, succinoglucan, caronate, chitin, chitosan, carboxymethyl Chitin, agar, polyvinyl alcohol, polyvinyl pyrrolidone, carboxy vinyl polymer, al Le-modified carboxyvinyl polymers, sodium polyacrylate, polyethylene glycol, and bentonite.

  As powders, the surface may be treated, powders such as mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, anhydrous silicic acid (silica), aluminum oxide, barium sulfate, etc .; Inorganic pigments of bengara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine blue, bitumen, titanium oxide, zinc oxide, which may be treated, mica titanium, fish phosphorus foil, which may be surface-treated Pearl agents such as bismuth oxychloride, red 202 which may be laked, red 228, red 226, yellow 4, blue 404, blue 5, yellow 505, red 230, red 230, red 223 Organic dyes such as No. Orange 201, Red 213, Yellow 204, Yellow 203, Blue 1, Blue 201, Purple 201, Red 204 etc., Polyethylene powder, Polymeta Methyl acrylic acid, nylon powder, organic powders such as organopolysiloxane elastomers, and the like.

  Examples of UV absorbers include para-aminobenzoic acid UV absorbers, anthranilic acid UV absorbers, salicylic acid UV absorbers, cinnamic acid UV absorbers, benzophenone UV absorbers, sugar UV absorbers, 2- (2) UV absorbers such as' -hydroxy-5'-t-octylphenyl) benzotriazole, 4-methoxy-4'-t-butyldibenzoylmethane, and the like can be mentioned.

  As the organic clay mineral, dimethyl distearyl ammonium modified hectorite, benzyl dimethyl stearyl ammonium modified hectorite, trioctylmethyl ammonium hectorite and the like can be mentioned.

  Hereinafter, the present invention will be described in more detail by way of examples, but the present invention is not limited thereto.

Preparation of <1> (W1 + W2) / O-Type Emulsified Composition The (W1 + W2) / O-type emulsified composition of the present invention was prepared according to the formulation shown in Table 1. That is, after stirring and mixing B to form phase D, B, C and D were added to obtain a (W1 + W2) / O type emulsion composition of Example 1.

<2> Observation of Emulsion The (W1 + W2) / O type emulsion composition of Example 1 was observed with a confocal laser scanning microscope (LSM). The measurement was performed using a Carl Zeiss Microsco LSM apparatus at 400 times magnification at room temperature.
The LSM observation image is shown in FIG. Each color of the fluorescent probe contained in each aqueous phase of W1 and W2 is clearly visible, and the (W1 + W2) / O type emulsion composition of the present invention has a stable composition without the two aqueous phases being united. It turned out that it was in the state of coexistence in things.

<3> Evaluation of stability over time
According to the formulation shown in Table 2, a (W1 + W2) / O type emulsion composition of the present invention was produced via D phase emulsification in the same manner as in Example 1 (Example 2).
For comparison, a (W1 + W2) / O type emulsion composition was prepared by the method disclosed in Patent Document 2 with the formulation shown in Table 3. That is, W is added to E and stirred and mixed to obtain a W1 / O type emulsion composition, and then added to T and stirred and mixed to obtain a (W1 + W2) / O type emulsion composition of Comparative Example 1. The
In addition, prescription of Table 2 and Table 3 is the same component and the same compounding quantity.

The (W1 + W2) / O type emulsion compositions of Example 2 and Comparative Example 1 prepared as described above are stored at 5, 20, 40 or 50 ° C. for 2 weeks or 1 month, respectively, and then placed at room temperature for 12 hours. From the above, the emulsion image was observed with a confocal laser microscope using the fluorescent probe in the aqueous phase as a marker. The results are shown in Table 4.
As shown in Table 4, the emulsion composition of the present invention can maintain stable coexistence in the composition without storage of the two aqueous phases even when stored under high temperature conditions. did it. It is considered that this is because the emulsion composition of the present invention has an aqueous phase covered with a very high modulus D-phase film by D-phase emulsification.

  According to the present invention, there is provided a water-in-oil emulsion composition having improved stability over time. In particular, a (W1 + W2) / O type emulsion composition stable over time even under high temperature conditions is provided, and two aqueous phases having different compositions can be stably present in the composition without unity. it can.

Claims (5)

At least one selected from polyhydric alcohol fatty acid ester, silicone surfactant, cationic surfactant, amphoteric surfactant, and anionic surfactant, and polyhydric alcohol, the water phase is D phase Water-in-oil emulsion composition covered with a membrane. The water-in-oil type emulsified composition according to claim 1 , comprising two or more aqueous phases different in composition. The water-in-oil type emulsion composition according to claim 1 or 2 , which is a skin external preparation. The water-in-oil emulsion composition according to claim 3 , which is a cosmetic. The manufacturing method of the water-in-oil type emulsion composition as described in any one of Claims 1-4 including the process of forming an emulsion by D phase emulsification.