JPH08217684A - Composition for decomposition of lipid - Google Patents

Abstract

PURPOSE: To obtain a. composition for decomposing lipid, having action promot ing decomposition of lipid. CONSTITUTION: This composition for decomposing lipid is obtained by blending 0.001-30.0wt.% of an extract extracted from a plant belonging to the genus Lavandula of the family Labiatac, e.g. Lavandula, angustifolia, lavender, Lavandula angustifolia pirenica, spike lavender or lavandin in an amount of 0.001-30.0wt.% based on the total composition in terms of dried material.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a lipid decomposing composition having an action of promoting lipid decomposition.

[0002]

2. Description of the Related Art Conventionally, in order to reduce excess fat in the body and maintain a lean body, in addition to various exercises and dietary restrictions, a massage gel for promoting metabolism in the body, It is known to use cosmetics such as cream. However, a skin external preparation for promoting the lipolysis of fat cells constituting fat and aiming at a slimming effect has not yet been developed.

On the other hand, regarding Lavandura plants belonging to the Lamiaceae family, for example, lavender and the like have been used as perfumes and bath salts as aromatic agents for a long time (JP-A-3-170).
13 and Japanese Examined Patent Publication No. 5-45567), recently, a skin external preparation has been known by utilizing the fact that lavender plants have cell activating properties and ultraviolet absorbing properties (Japanese Patent Application Laid-Open No. 64-6456). -83013). However, the lipolysis-promoting action of adipocytes possessed by the plant of the genus Lauandra is not known so far.

[0004]

[Means for Solving the Problems] The present inventors have conducted extensive studies as to whether or not there is a substance that accelerates lipolysis of adipocytes, and as a result, found that an extract extracted from the genus Lauandura belonging to the Lamiaceae has the effect. The present invention has been completed.

That is, the present invention is a composition for degrading lipids, which comprises an extract extracted from a plant of the genus Lauandura of the Lamiaceae family as an active ingredient. The composition for lipolysis in the present invention is preferably a skin external preparation for lipolysis.

The structure of the present invention will be described in detail below. The Lamiaceae plant used in the present invention has about 20 plants.
Includes seeds residue, for example, Lauandura, Angustifolia, Lavender, Lauandra Angustifolia Pyreneika, Spike Lavender, Lavandin and the like. As these plants, flowers, stems, fruits, seeds, roots and whole plants are used, and flowers are preferably used.
The extraction method is not particularly limited, for example, water, hydrophilic organic solvents such as alcohol, or a mixed solution thereof,
Alternatively, it is extracted with a polyhydric alcohol such as glycerin or 1,3-butylene glycol, or a mixed liquid of water and a polyhydric alcohol. The compounding amount of the extract in the composition is 0.001 to 30.0 in terms of dry matter in the composition for lipolysis.
%, Preferably 0.01-10.0% by weight.
When the amount of the extract compounded is less than 0.001% by weight, a sufficient lipolytic effect is not obtained, and even when it exceeds 30.0% by weight, the enhancement of the lipolytic effect is not observed.

If desired, the composition for decomposing lipids of the present invention may contain various components generally used in cosmetics, pharmaceuticals, etc. within a range that does not impair the effects of the present invention. Examples of such components include the following.

Vitamin oils, vitamins A such as retinol and retinol acetate, riboflavin, riboflavin butyrate,
Vitamin B ₂ such as flavin adenine nucleotide, pyridoxine hydrochloride, vitamin B ₆ such as pyridoxine dioctanoate, L-ascorbic acid, L-ascorbic acid dipalmitate, L-ascorbic acid-2
-Vitamin Cs such as sodium sulfate, L-ascorbic acid phosphoric acid ester, DL-α-tocopherol-L-ascorbic acid phosphoric acid diester dipotassium, calcium pantothenate, D-pantothenyl alcohol, pantothenyl ethyl ether, acetylpantothenyl Pantothenic acids such as ethyl ether, vitamin Ds such as ergocalciferol, cholecalciferol, nicotinic acids such as nicotinic acid, nicotinamide, benzyl nicotinate, α-tocopherol, tocopherol acetate, DL-α-tocopherol nicotinate, Examples thereof include vitamin Es such as DL-α-tocopherol succinate, vitamins such as vitamin P and biotin.

The liquid oils and fats include avocado oil, camellia oil, evening primrose oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil,
Castor oil, linseed oil, safflower oil, cottonseed oil, eno oil,
Soybean oil, peanut oil, teaseed oil, kaya oil, rice bran oil, cinnamon oil, Japanese tung oil, jojoba oil, germ oil, triglycerin, glyceryl trioctanoate, glyceryl triisopalmitate, etc., are solid cacao. Fat, coconut oil, horse fat, hydrogenated coconut oil, palm oil, beef tallow, sheep fat, hydrogenated beef tallow, palm kernel oil, pork fat, beef bone fat, mokuro kernel oil, hydrogenated oil, beef tallow, mokurou, hydrogenated castor oil Examples of waxes include beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, ivota wax, whale wax, montan wax, nukarou, lanolin, capock wax, lanolin acetate, liquid lanolin, sugarcane wax, lanolin fatty acid isopropyl, hexyl laurate, reduced lanolin. , Jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether Hydrocarbon oils such as POE lanolin alcohol acetate, POE cholesterol ether, lanolin fatty acid polyethylene glycol, and POE hydrogenated lanolin alcohol ether include liquid paraffin, ozokerite, squalene, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, etc. Oil is included.

Examples of the higher fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, 12-hydroxystearic acid, undecylenic acid, tall acid, isostearic acid, linoleic acid and linolein. Acid, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and the like.

Examples of the higher alcohols include linear alcohols such as lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol and cetostearyl alcohol, monostearyl glycerin ether (batyl alcohol), 2-decyltetradecyl alcohol. Examples thereof include branched chain alcohols such as knoll, lanolin alcohol, cholesterol, phytosterol, hexyldecanol, isostearyl alcohol, and octyldodecanol.

As synthetic ester oils, isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate,
Decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, 1
Cholesteryl 2-hydroxystearate, ethylene glycol di-2-ethylhexylate, dipentaerythritol fatty acid ester, N-alkyl glycol monoisostearate, neopentyl glycol dicaprate, diisostearyl malate, glycerin di-2-heptylundecanoate. Trimethylolpropane tri-2-ethylhexylate, trimethylolpropane triisostearate, penta-2-erythritol tetrahexylhexanoate, glycerin tri-2-ethylhexylate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glycerin trimyristate, tri-2-
Heptylundecanoic acid glyceride, castor oil fatty acid methyl ester, oleic acid oil, cetostearyl alcohol, acetoglyceride, 2-heptylundecyl palmitate, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, adipic acid Di-2-heptyl undecyl, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate. , Ethyl acetate, butyl acetate, amyl acetate, triethyl citrate and the like.

Examples of the silicone include chain polysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane and methylhydrogenpolysiloxane, and cyclic polymers such as decamethylpolysiloxane, dodecamethylpolysiloxane and tetramethyltetrahydrogenpolysiloxane. Examples thereof include polysiloxane, silicone resin having a three-dimensional network structure, and silicone rubber.

Examples of moisturizers include polyethylene glycol, propylene glycol, glycerin, 1,3
-Butylene glycol, hexylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, caronic acid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, bile salt, dl-pyrrolidone carboxylate , Short-chain soluble collagen, diglycerin (EO) PO adduct, Isyobara extract, Yarrow extract, Merrilot extract and the like.

As the ultraviolet absorber, para-aminobenzoic acid (hereinafter abbreviated as PABA), PABA monoglycerin ester, N, N-dipropoxy PABA ethyl ester, N, N-diethoxy PABA ethyl ester, N,
Benzoic acid type UV absorbers such as N-dimethyl PABA ethyl ester, N, N-dimethyl PABA butyl ester, anthranilic acid type UV absorbers such as homomenthyl-N-acetylanthranilate, amyl salicylate,
Salicylic acid type UV absorbers such as menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate, octylcinnamate, ethyl-4-isopropylcinnamate, methyl-2,5-diisopropylcinnamate , Ethyl-2,
4-diisopropylcinnamate, methyl-2,4-diisopropylcinnamate, propyl-p-methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, octyl-p-methoxycinnamate (2- Ethylhexyl-p
-Methoxycinnamate), 2-ethoxyethyl-p-
Methoxycinnamate, cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate, glyceryl mono-2-ethylhexanoyl-diparamethoxy Cinnamates, 3,4,5-trimethoxycinnamic acid 3-methyl-4- [methylbis (trimethylsiloxy) silyl] butyl and other cinnamic acid type UV absorbers, 2,4-dihydroxybenzophenone, 2,2 '
-Dihydroxy-4-methoxybenzophenone, 2,
2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2 ', 4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2
-Ethylhexyl-4'-phenyl-benzophenone-
Benzophenone-based UV absorbers such as 2-carboxylate, hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone, 3-
(4'-methylbenzylidene) -d, l-camphor, 3
-Benzylidene-d, l-camphor, urocanic acid,
Urocanic acid ethyl ester, 2-phenyl-5-methylbenzoxazole, 2,2'-hydroxy-5-methylphenylbenzotriazole, 2- (2'-hydroxy-5'-t-octylphenyl) benzotriazole, 2 -(2'-hydroxy-5'-methylphenylbenzotriazole, dibenzalazine, dianisoylmethane, 4-methoxy-4'-t-butyldibenzoylmethane, 5- (3,3-dimethyl-2-norbornylidene)
-3-Pentan-2-one and the like can be mentioned.

Examples of the anionic surfactant include a base for soap, a fatty acid soap such as sodium laurate and sodium palmitate, a higher alkyl sulfate ester salt such as sodium lauryl sulfate and K lauryl sulfate,
POE lauryl sulfate triethanolamine, POE sodium lauryl sulfate and other alkyl ether sulfate salts, lauroyl sarcosine sodium and other N-acyl sarcosinic acid, N-myristoyl-N-methyl taurine sodium, coconut oil fatty acid methyl tauride sodium,
Higher fatty acid amide sulfonate such as sodium lauryl methyl tauride, sodium phosphate ester such as POE oleyl ether phosphate, POE stearyl ether phosphate, sodium di-2-ethylhexyl sulfosuccinate, monolauroyl monoethanolamide polyoxyethylene Sodium sulfosuccinate, lauryl polypropylene glycol sulfosuccinate such as sodium sulfosuccinate, sodium linear dodecylbenzene sulfonate, triethanolamine linear dodecyl benzene sulfonate, alkylbenzene sulfonates such as linear dodecyl benzene sulfonate, monosodium N-lauroyl glutamate , N-stearoyl glutamate disodium, N-myristoyl-L-glutamate monosodium, etc. Acyl glutamate, hardened coconut oil fatty acid glycerin sodium sulfate and other higher fatty acid ester sulfate ester salt, funnel oil and other sulfated oil, POE alkyl ether carboxylic acid, POE alkyl allyl ether carboxylate, α-olefin sulfonate, higher salt Fatty acid ester sulfonate, secondary alcohol sulfate ester salt, higher fatty acid alkylolamide sulfate ester salt,
Lauroyl monoethanolamide sodium succinate,
N-palmitoyl aspartic acid ditriethanolamine, sodium caseinate and the like can be mentioned.

Examples of the cationic surfactant include alkyltrimethylammonium salts such as stearyltrimethylammonium chloride and lauryltrimethylammonium chloride, distearyldimethylammonium dialkyldimethylammonium chloride, poly (N, N'-dimethyl-3, chloride). 5-methylene piperidinium), an alkylpyridinium salt such as cetylpyridinium chloride, an alkyl quaternary ammonium salt, an alkyldimethylbenzyl ammonium salt, an alkylisoquinolinium salt, a dialkylmorphonium salt, a POE alkylamine, an alkylamine salt, Examples thereof include polyamine fatty acid derivatives, amyl alcohol fatty acid derivatives, benzalkonium chloride and benzethonium chloride.

Examples of the amphoteric surfactant include 2-undecyl-N, N, N- (hydroxyethylcarboxymethyl) -2-imidazoline sodium and 2-cocoyl-2-imidazolinium hydroxide-1-carboxy. Imidazoline-based amphoteric surfactants such as ethyloxy disodium salt, 2-heptadecyl-N-carboxymethyl-
N-hydroxyethyl imidazolinium betaine, lauryl dimethylamino acetic acid betaine, alkyl betaine,
Examples thereof include betaine-based surfactants such as amidobetaine and sulfobetaine.

Examples of lipophilic nonionic surfactants include sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, Penta-2-ethylhexylate diglycerol sorbitan, tetra-2-ethylhexylate diglycerol sorbitan, and other sorbitan fatty acid esters, monocotton seed oil fatty acid glycerin, monoerucate glycerin, sesquioleate glycerin, monostearate glycerin, α,
Glycerin polyglycerin fatty acids such as α'-oleic acid glycerin pyroglutamate, glyceryl monostearate malic acid, propylene glycol fatty acid esters such as propylene glycol monostearate, hydrogenated castor oil derivative, glycerin alkyl ether, polyoxyethylene methyl Examples thereof include polysiloxane copolymers.

Examples of hydrophilic nonionic surfactants include POE sorbitan monooleate, POE-sorbitan monostearate, POE sorbitan tetraoleate and other POE sorbitan fatty acid esters, POE.
-Sorbit monolaurate, POE-Sorbit monooleate, POE-Sorbit pentaoleate, P
POE sorbit fatty acid esters such as OE-sorbit monostearate, POE-glycerin monostearate, POE-glycerin monoisostearate, PO
POE glycerin fatty acid esters such as E-glycerin triisostearate, POE monooleate, POE
POE fatty acid esters such as distearate, POE monodioleate, ethylene glycol distearate,
POE lauryl ether, POE oleyl ether, P
OE stearyl ether, POE behenyl ether, P
POE alkyl ethers such as OE2-octyl dodecyl ether and POE cholestanol ether, POE alkyl phenyl ethers such as POE octyl phenyl ether, POE nonyl phenyl ether, POE dinonyl phenyl ether, and Pluronic types such as Pluronic, POE / POP Cetyl ether, POE / PO
P2-decyl tetradecyl ether, POE / POP monobutyl ether, POE / POP hydrogenated lanolin, PO
POE / POP alkyl ethers such as E / POP glycerin ether, tetra-POE / tetra-POP ethylenediamine condensates such as Tetronic, POE castor oil,
POE hydrogenated castor oil, POE hydrogenated castor oil monoisostearate, POE hydrogenated castor oil triisostearate,
POE hydrogenated castor oil monopyroglutamic acid monoisostearate diester, POE hydrogenated castor oil maleic acid, and other POE castor oil hydrogenated castor oil derivatives, POE sorbitol beeswax, and other POE beeswax lanolin derivatives, coconut oil fatty acid diethanolamide, lauric acid monoethanolamide Alkanol amides such as fatty acid isopropanolamide, POE propylene glycol fatty acid ester, POE alkylamine, POE fatty acid amide, sucrose fatty acid ester, POE nonylphenylformaldehyde condensate, alkylethoxydimethylamine oxide, and trioleylphosphoric acid.

In addition, antiseptics such as ethyl paraben and butyl paraben, glycyrrhizic acid derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, zinc oxide, anti-inflammatory agents such as allantoin, placenta extract, glutathione, and Yukinoshita extract whitening agents , Oataku, Ouren, Sikon, Peony, Assembly, Birch, Sage,
Loquats, carrots, aloe, mallow, iris, grapes, quinine, loofah, lilies, saffron, senkyu, ginger, capsicum, ononis, rosemary, garlic, capsicum, chimpi, toki, seaweed,
Extracts such as tea, royal jelly, photosensitizers, cholesterol derivatives, activators such as calf blood extracts, nonyl acid warenylamide, nicotinic acid benzyl ester, nicotinic acid β
-Butoxyethyl ester, capsaicin, zingerone, cantharis tincture, ictamol, caffeine, tannic acid, α-borneol, tocopherol nicotinate, inositol hexanicotinate, cyclandrate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthin, γ- There are blood circulation promoters such as oryzanol, and antiseborrheic agents such as sulfur and thiantol.

Examples of natural water-soluble polymers include, for example, araavia gum, tragacanth gum, galactan, guar gum, carob gum, karaya gum, carrageenan, pectin, agar, quince seed (quince), arge colloid (cassius extract), starch (rice, corn, Potatoes, wheat), plant-based polymers such as glycyrrhizinate, microbial-based polymers such as xanthan gum, dextran, succinoglucan, and vullan, collagen,
Animal-based macromolecules such as casein, albumin and gelatin can be mentioned.

As the semi-synthetic water-soluble polymer, for example,
Starch polymers such as carboxymethyl starch and methyl hydroxypropyl starch, methyl cellulose, nitrocellulose, ethyl cellulose, methyl hydroxypropyl cellulose, hydroxyethyl cellulose, sodium cellulose sulfate, hydroxypropyl cellulose, sodium carboxymethyl cellulose (CM
C), crystalline cellulose, cellulose-based polymers such as cellulose powder, and alginic acid-based polymers such as sodium alginate and propylene glycol alginate.

As the synthetic water-soluble polymer, for example, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, vinyl polymers such as carboxyvinyl polymer (Carbopol), polyethylene glycol.
Polyoxyethylene polymers such as 2,000, 4,000 and 6,000, polyoxyethylene polyoxypropylene copolymer copolymers, acrylic polymers such as sodium polyacrylate, polyethyl acrylate and polyacrylamide, polyethyleneimine, Examples include cationic polymers.

Examples of the inorganic water-soluble polymer include bentonite, AlMg silicate (veegum), laponite, hectorite, and silicic acid anhydride.

Examples of the thickener include gum arabic,
Carrageenan, karaya gum, tragacanth gum, carob gum, quince seed (quince), casein, dextrin, gelatin, sodium pectate, sodium alginate, methyl cellulose, ethyl cellulose,
CMC, hydroxyethyl cellulose, hydroxypropyl cellulose, PVA, PVM, PVP, sodium polyacrylate, carboxyvinyl polymer, locust bean gum, guar gum, tamarind gum, dialkyldimethylammonium sulfate cellulose, xanthan gum, magnesium aluminum silicate, bentonite,
Hectorite and the like can be mentioned.

As powder components, talc, kaolin, mica, sericite, muscovite, phlogopite, synthetic mica, phlogopite, biotite, lithia mica, vermiculite,
Magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, tungstate metal salt, magnesium, silica, zeolite, barium sulfate, calcined calcium sulfate (calculated gypsum), calcium phosphate, Fluorapatite, hydroxyapatite, ceramic powder, metallic soap (zinc myristate, calcium palmitate, aluminum stearate), inorganic powder such as boron nitride, polyamide resin powder (nylon powder), polyethylene powder, polymethylmethacrylate powder, polystyrene Powder, styrene-acrylic acid copolymer resin powder, benzoguanamine resin powder, polytetrafluoroethylene powder, organic powder such as cellulose powder, inorganic white such as titanium dioxide and zinc oxide Fee, iron oxide (red iron oxide),
Inorganic red pigments such as iron titanate, inorganic brown pigments such as γ-iron oxide, inorganic yellow pigments such as yellow iron oxide and ocher, and inorganic black pigments such as black iron oxide, carbon black, and lower titanium oxide. , Mango Violet, Cobalt Violet and other inorganic purple pigments, Chromium oxide, Chromium hydroxide, Cobalt titanate and other inorganic green pigments, Ultramarine blue, Navy blue and other inorganic blue pigments, Titanium oxide coated mica, Titanium oxide coated oxychloride Bismuth, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, pearl pigments such as fish scale foil, aluminum powder,
Metal powder pigments such as copper powder, red 201, red 202, red 204, red 205, red 220
No., Red 226, Red 228, Red 405, Orange 203, Orange 204, Yellow 205, Yellow 401
No., organic pigments such as Blue No. 404, Red No. 3, Red 10
4, Red 106, Red 227, Red 230, Red 401, Red 505, Orange 205, Yellow 4,
Organic pigments such as zirconium, barium or aluminum lake such as yellow 5, yellow 202, yellow 203, green 3 and blue 1; natural pigments such as chlorophyll and β-carotene; perfume, water, alcohol, titanium yellow,
Coloring agents such as cursamine and safflower red can be appropriately blended as necessary.

The dosage form of the composition for decomposing lipids of the present invention is arbitrary, for example, an oily preparation, a solubilization system of a lotion, an emulsion system such as an emulsion or a cream, or an ointment, a dispersion or a powder. Can be taken.

[0029]

EXAMPLES The present invention will be described in more detail with reference to examples. The present invention is not limited to this. The blending amount is% by weight. Prior to the examples, the effect of the present invention is shown by experimental data.

(Evaluation method) The isolation of adipocytes from adipose tissue was carried out by the method of Rodbell (M. Rodbell, JBC, 239 (2),
1964). Human adipose tissue obtained by liposuction was cut into 2-3 mm pieces and incubated (37 ° C, 45-60 minutes) in a 0.05% collagenase solution (containing Hanks buffer and 4% glucose). . Then, the mixture was filtered to remove undigested adipose tissue, and centrifuged (1,000 rpm, 1 minute). Since the specific gravity of adipocytes is less than 1, they float above. The lower layer solution was removed, and a culture solution (199 medium containing 10% newborn calf serum) was added and redispersed. Repeat centrifugation and medium addition twice,
Collagenase was removed. Finally 30m of the medium described in Table 1
1 was added to disperse the cells, and the cells were cultivated for 1 day in rotation. The extract concentration in each sample was 0.1% by weight. The lipid content of adipocytes before and after the culture was quantified using Triglyceride-Test Wako (Wako Pure Chemical Industries, Ltd.) (a color reagent for lipid quantification) to measure the amount of degraded lipid (mg / tube). The experimental results are shown in Table 1.

[0031]

[Table 1] ───────────────────────────── Sample Amount of degraded lipid (mg / tube) ──────── ───────────────────── Unadded 0.35 ± 0.09 Lauandra extract 1.12 ± 0.10 Lavender extract 1.50 ± 0.12 Lavandin extract 1.34 ± 0.15 ────── ───────────────────────

From Table 1, it can be seen that the extract of the plant of the genus Lauandra belonging to the Lamiaceae promotes lipolysis.

Example 1 Lotion (1) Lauandra extract 0.5% by weight (2) Tocopherol acetate 0.01 (3) Glycerin 4.0 (4) 1,3-Butylene glycol 4.0 (5) Tea extract 0.1 (6) Ethanol 7.0 (7) Polyoxyethylene (18) Oleyl alcohol ether 0.5 (8) Methylparaben 0.2 (9) Citric acid 0.05 (10) Sodium citrate 0.1 (11) Perfume 0.05 (12) Purified water Residual

(Manufacturing Method) Citric acid, sodium citrate, glycerin, 1,3-butylene glycol, tea extract and Lauandura extract are dissolved in purified water (aqueous phase). Separately, polyoxyethylene (18) oleyl alcohol ether, tocopherol acetate, perfume, and methylparaben were dissolved in ethanol, and this was added to the above aqueous phase to solubilize it, followed by filtration to obtain a lotion.

Example 2 Cream (1) Cetostearyl alcohol 3.5% by weight (2) Squalane 40.0 (3) Beeswax 3.0 (4) Reduced lanolin 5.0 (5) Ethylparaben 0.3 (6) Polyoxyethylene (20) Sorbitan monopalmitin Acid ester 2.0 (7) Stearic acid monoglyceride 2.0 (8) Sodium N-stearoylglutamate 0.5 (9) 2-Hydroxy-4-methoxybenzophenone 1.0 (10) Retinol acetate 2.0 (11) Evening primrose oil 0.05 (12) Perfume 0.05 (13) ) Lavender extract 1.0 (l4) 1,3-butylene glycol 5.0 (15) Dextran sulfate sodium 0.1 (16) Purified water Residual

(Production method) (1) to (12) are melted by heating and 70 ° C.
Add to (13)-(16) warmed to with stirring. After homogenizing with a homomixer to make the emulsified particles fine, the mixture was rapidly cooled with stirring to obtain a cream.

Example 3 Emulsion (1) Stearic acid 1.5% by weight (2) Cetyl alcohol 0.5 (3) Beeswax 2.0 (4) Polyoxyethylene (10) monooleate 1.0 (5) Octyl methoxycinnamate 2.0 ( 6) Birch extract 0.2 (7) Lavandin extract 5.0 (8) Sodium hyaluronate 0.01 (9) Triethanolamine 0.75 (10) Glycerin 7.0 (11) Inosit 0.5 (12) Ginseng extract 0.5 (13) Ethylparaben 0.3 ( 14) Fragrance 0.03 (15) Purified water Residue

(Production method) Birch extract, lavandin extract, sodium hyaluronate, glycerin, inosit, ginseng extract, triethanolamine were added to purified water to obtain 7
Keep at 0 ° C (aqueous phase). Mix with other ingredients and heat to dissolve 7
Keep at 0 ° C (oil phase). The oil phase is added to the aqueous phase for preliminary emulsification, and the mixture is homogenized with a homomixer. Then, it was rapidly cooled with stirring to obtain an emulsion.

Example 4 Foam pack (1) Spike lavender extract 0.1% by weight (2) Seaweed extract 1.0 (3) 1,3-butylene glycol 5.0 (4) Glycerin 7.0 (5) Methylparaben 0.1 (6) Water Potassium oxide 0.15 (7) Stearic acid 0.5 (8) Myristic acid 1.0 (9) Batyl alcohol 1.5 (10) Polyoxyethylene (60) Hydrogenated castor oil 3.0 (11) Perfume 0.05 (12) Liquefied petroleum gas 6.0 (13) Dimethyl ether 3.0 (14) Purified water Residual

(Production method) (1) to (6) were added to (14) and dissolved by heating at 70 ° C., and (7) to (11) heated and stirred at 75 ° C. were added thereto, and the mixture was thoroughly mixed. Cool with stirring. This was filled in a container, and finally (12) and (13) were filled as a propellant to obtain a foam pack.

Example 5 Ointment (1) Angustifolia extract 10.0% by weight (2) Tocopherol acetate 1.0 (3) Retinol palmitate 0.5 (4) Stearyl alcohol 18.0 (5) Mokurou 20.0 (6) Polyoxyethylene (20 ) Monooleate 0.25 (7) Glycerin monostearate 0.3 (8) Vaseline 40.0 (9) Purified water Residue

(Production method) The angustifolia extract was added to purified water and dissolved, and the mixture was kept at 70 ° C (aqueous phase). The remaining components are mixed and dissolved at 70 ° C. (oil phase). The oil phase was added to the aqueous phase, and the mixture was uniformly emulsified with a homomixer and then cooled to obtain an ointment.

Example 6 Emulsion for massage (1) Stearic acid 1.5% by weight (2) Cetyl alcohol 0.5 (3) Polyoxyethylene (10) Monooleate 1.0 (4) Vaseline 3.0 (5) Squalane 10.0 (6) Liquid paraffin 5.0 (7) Glycerin 7.0 (8) 1,3-butylene glycol 5.0 (9) Triethanolamine 0.75 (10) Tocopherol acetate 0.05 (11) Lauandra Angustifolia pyrenica extract 1.0 (12) Ethylparaben 0.25 (13) Fragrance 0.02 (14) Purified water Residue

(Manufacturing method) In purified water, extract of Lauandra angustifolia pyrenika, glycerin,
1,3-Butylene glycol and triethanolamine are added and kept at 70 ° C. (aqueous phase). The other ingredients are mixed, dissolved by heating and kept at 70 ° C. (oil phase). The oil phase is added to the aqueous phase for preliminary emulsification, and the mixture is homogenized with a homomixer. Then, it was rapidly cooled with stirring to obtain a milky lotion for massage.

Example 7 Massage Gel (1) Lauandra Extract 2.0% by Weight (2) 1,3-Butylene Glycol 30.0 (3) Glycerin 40.0 (4) Carboxyvinyl Polymer 0.45 (5) Polyoxyethylene (8) Methyl Polysiloxane 0.5 (6) Squalane 0.5 (7) Potassium hydroxide 0.15 (8) Perfume 0.15 (9) Purified water Residual

(Manufacturing method) Lauandura extract in purified water,
Dissolve 1,3-butylene glycol, glycerin and carboxyvinyl polymer. Separately, a mixture of squalane, polyoxyethylene (8) methylpolysiloxane, and a fragrance was added, and then potassium hydroxide was added to obtain a massage gel.

Example 8 Serum (1) Lavender extract 20.0% by weight (2) Inosit 0.5 (3) Caffeine 0.1 (4) Placenta extract 0.1 (5) Sodium hyaluronate 0.01 (6) Glycerin 10.0 (7) 1,3-Butylene glycol 5.0 (8) Carboxyvinyl polymer 0.3 (9) Ethanol 7.0 (10) Polyoxyethylene (18) Oleyl alcohol ether 0.8 (11) Macadamia nut oil 0.1 (12) Evening primrose oil 0.01 (13) Tocopherol acetate 0.01 (14) Methylparaben 0.15 (15) Perfume 0.1 (16) Potassium hydroxide 0.08 (17) Purified water Residual

(Production method) (1) to (8) are dissolved in (17) and separately
What melt | dissolved (10)-(15) in (9) is added. afterwards,
(16) was added to obtain a serum.

[0049]

Industrial Applicability As described above, the composition for decomposing lipids of the present invention is excellent in the effect of promoting the decomposition of lipids by incorporating the extract of the plant of the genus Lauandra in the Lamiaceae.

Claims (3)

[Claims] 1. A composition for degrading lipids, which comprises an extract extracted from a plant of the genus Lauandra, belonging to the Lamiaceae family, as an active ingredient. 2. The content of the extract extracted from the plant of the genus Lauandra, belonging to the Lamiaceae, is 0.00 based on the total amount of the composition as a dry matter.
The composition for lipolysis according to claim 1, which is 1 to 30.0% by weight. 3. The composition for lipolysis according to claim 1, wherein the composition for lipolysis is an external preparation for skin for lipolysis.