JP6465857B2 - 外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬 - Google Patents

外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬 Download PDF

Info

Publication number
JP6465857B2
JP6465857B2 JP2016503010A JP2016503010A JP6465857B2 JP 6465857 B2 JP6465857 B2 JP 6465857B2 JP 2016503010 A JP2016503010 A JP 2016503010A JP 2016503010 A JP2016503010 A JP 2016503010A JP 6465857 B2 JP6465857 B2 JP 6465857B2
Authority
JP
Japan
Prior art keywords
reagent
cell
cosmotrope
buffer
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016503010A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016512693A5 (cg-RX-API-DMAC7.html
JP2016512693A (ja
Inventor
ベイカー，トニー，ケイ
Original Assignee
トラッキー・アプライド・ゲノミクス，エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by トラッキー・アプライド・ゲノミクス，エルエルシー filed Critical トラッキー・アプライド・ゲノミクス，エルエルシー
Publication of JP2016512693A publication Critical patent/JP2016512693A/ja
Publication of JP2016512693A5 publication Critical patent/JP2016512693A5/ja
Application granted granted Critical
Publication of JP6465857B2 publication Critical patent/JP6465857B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2016503010A 2013-03-15 2014-03-14 外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬 Active JP6465857B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361798627P 2013-03-15 2013-03-15
US61/798,627 2013-03-15
PCT/US2014/029198 WO2014144682A1 (en) 2013-03-15 2014-03-14 Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue

Publications (3)

Publication Number Publication Date
JP2016512693A JP2016512693A (ja) 2016-05-09
JP2016512693A5 JP2016512693A5 (cg-RX-API-DMAC7.html) 2017-04-13
JP6465857B2 true JP6465857B2 (ja) 2019-02-06

Family

ID=51528685

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016503010A Active JP6465857B2 (ja) 2013-03-15 2014-03-14 外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬

Country Status (17)

Country Link
US (5) US9113623B2 (cg-RX-API-DMAC7.html)
EP (2) EP2970878B1 (cg-RX-API-DMAC7.html)
JP (1) JP6465857B2 (cg-RX-API-DMAC7.html)
CN (2) CN105121629B (cg-RX-API-DMAC7.html)
CA (1) CA2941929C (cg-RX-API-DMAC7.html)
CY (1) CY1120801T1 (cg-RX-API-DMAC7.html)
DK (1) DK2970878T3 (cg-RX-API-DMAC7.html)
ES (1) ES2684582T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20181352T1 (cg-RX-API-DMAC7.html)
HU (1) HUE039933T2 (cg-RX-API-DMAC7.html)
LT (1) LT2970878T (cg-RX-API-DMAC7.html)
PL (1) PL2970878T3 (cg-RX-API-DMAC7.html)
PT (1) PT2970878T (cg-RX-API-DMAC7.html)
RS (1) RS57900B1 (cg-RX-API-DMAC7.html)
SI (1) SI2970878T1 (cg-RX-API-DMAC7.html)
SM (1) SMT201800457T1 (cg-RX-API-DMAC7.html)
WO (1) WO2014144682A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2970878T (lt) 2013-03-15 2018-11-12 Truckee Applied Genomics, Llc Vėžio ląstelių chirurginiu būdu pašalintame audinyje gyvybingumo palaikymo būdai ir reagenatai
EP3224359B1 (en) 2014-11-25 2023-10-25 Bio-Rad Laboratories, Inc. Arginine improves polymerase storage stability
CN107333750A (zh) * 2017-06-11 2017-11-10 成都吱吖科技有限公司 一种长时血液细胞稳定剂
WO2021055170A1 (en) * 2019-09-17 2021-03-25 Longhorn Vaccines And Diagnostics, Llc Multipurpose compositions for collecting and transporting biological material
WO2022010916A1 (en) * 2020-07-07 2022-01-13 Truckee Applied Genomics, Llc Cell preservation reagents and methods of use
CN117063915A (zh) * 2023-08-17 2023-11-17 镜像绮点(上海)细胞技术有限公司 原代肿瘤细胞冻存液

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409826A (en) * 1993-06-08 1995-04-25 Coulter Corporation Preserved, non-infectious control cells prepared by the modulation or modification of normal cells
JP2000509018A (ja) * 1996-03-26 2000-07-18 イーライ・リリー・アンド・カンパニー 肥満タンパク質製剤
US20010007673A1 (en) 1999-11-12 2001-07-12 Merrill Seymour Goldenberg Sustained-release delayed gels
US20080064108A1 (en) 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
JP2001526051A (ja) 1997-12-10 2001-12-18 シエラ ダイアグノスティクス，インク． 体液中のｄｎａを保存するための方法及び試薬
DE60116673T2 (de) * 2000-12-04 2006-08-10 Lymphotec Inc. Zellkonservierungsflüssigkeit und verfahren zur zellkonservierung mit dieser flüssigkeit
KR20020066778A (ko) 2001-02-13 2002-08-21 한국과학기술연구원 체내 난흡수 물질의 흡수촉진용 조성물과 제형 및 그의제조방법
WO2008111981A1 (en) 2007-03-14 2008-09-18 Sierra Molecular Corporation Compositions, systems, and methods for preservation of macromolecules
US20040214203A1 (en) * 2002-12-12 2004-10-28 Oncotech, Inc. Genes related to sensitivity and resistance to chemotherapeutic drug treatment
US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
KR20090098957A (ko) 2006-09-12 2009-09-18 시에라 몰레큘러 코포레이션 카오트로프의 완충용액을 사용하는 핵산을 대상으로 하는 분자분석 간섭의 제거
US8080645B2 (en) * 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US8652782B2 (en) * 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
AU2007308865A1 (en) 2006-10-27 2008-05-02 Sierra Molecular Corporation Penetratable septum cap
EP2094846B8 (en) 2006-12-13 2013-10-16 Roche Diagnostics GmbH Use of tde for the isolation of nucleic acids
JP2010535013A (ja) 2007-03-14 2010-11-18 シエラ モレキュラー コーポレイション 細胞および／または高分子の保存および／または安定化のための組成物、システムおよび方法
CA2705417A1 (en) * 2007-11-12 2009-05-22 Bipar Sciences, Inc. Treatment of uterine cancer and ovarian cancer with a parp inhibitor alone or in combination with anti-tumor agents
US20100003748A1 (en) * 2008-07-03 2010-01-07 Tony Baker Compositions, systems, and methods for stabilization of a cell and/or macromolecule
US20110165611A1 (en) 2008-09-04 2011-07-07 Chun Li Dual modality detection of apoptosis
US9133343B2 (en) 2009-11-30 2015-09-15 Enzo Biochem, Inc. Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications
CN102318597B (zh) * 2011-08-19 2013-04-03 张雪云 一种液基细胞保存液组合物及其制备方法
LT2970878T (lt) 2013-03-15 2018-11-12 Truckee Applied Genomics, Llc Vėžio ląstelių chirurginiu būdu pašalintame audinyje gyvybingumo palaikymo būdai ir reagenatai

Also Published As

Publication number Publication date
WO2014144682A4 (en) 2014-12-24
HRP20181352T1 (hr) 2018-12-14
US20170215410A1 (en) 2017-08-03
CA2941929C (en) 2021-02-23
US20150230454A1 (en) 2015-08-20
US9113623B2 (en) 2015-08-25
CA2941929A1 (en) 2014-09-18
SI2970878T1 (sl) 2019-02-28
EP2970878A1 (en) 2016-01-20
EP2970878B1 (en) 2018-05-23
US20140272921A1 (en) 2014-09-18
US10772318B2 (en) 2020-09-15
CY1120801T1 (el) 2019-12-11
SMT201800457T1 (it) 2018-11-09
ES2684582T3 (es) 2018-10-03
PT2970878T (pt) 2018-10-09
HK1220481A1 (en) 2017-05-05
EP3581643A1 (en) 2019-12-18
CN112806352A (zh) 2021-05-18
RS57900B1 (sr) 2019-01-31
EP2970878A4 (en) 2016-08-03
CN105121629A (zh) 2015-12-02
LT2970878T (lt) 2018-11-12
PL2970878T3 (pl) 2019-01-31
HUE039933T2 (hu) 2019-02-28
US20160235055A1 (en) 2016-08-18
WO2014144682A8 (en) 2015-08-13
JP2016512693A (ja) 2016-05-09
DK2970878T3 (en) 2018-09-03
US9565852B2 (en) 2017-02-14
US9445586B2 (en) 2016-09-20
CN105121629B (zh) 2020-12-18
US20150327539A1 (en) 2015-11-19
WO2014144682A1 (en) 2014-09-18
US9949474B2 (en) 2018-04-24

Similar Documents

Publication Publication Date Title
US10772318B2 (en) Methods and reagents for maintaining the visability of cancer cells in surgically removed tissue
Viertler et al. A new technology for stabilization of biomolecules in tissues for combined histological and molecular analyses
EP3705582B1 (en) Compositions and methods for dna and rna extraction from tissue samples
US11313772B2 (en) Fixatives and methods of use
US20230357825A1 (en) Cell preservation reagents and methods of use
CN105684989A (zh) 一种肝癌pdx标准化模型库
Kap et al. The influence of tissue procurement procedures on RNA integrity, gene expression, and morphology in porcine and human liver tissue
Welson et al. Evaluation of time passed since death by examination of oxidative stress markers, histopathological, and molecular changes of major organs in male albino rats
CN114875022B (zh) 尿液保存液、保存方法和尿液保存管
Nguyen et al. Ovarian tissue cryopreservation and transplantation in patients with central nervous system tumours
Das et al. Establishing a standardized method for the effective intraoperative collection and biological preservation of brain tumor tissue samples using a novel tissue preservation system: a pilot study
Kopanja et al. Proliferation defects and genome instability in cells lacking Cul4A
Gillio-Meina et al. Translational research in pediatrics IV: solid tissue collection and processing
Lugli et al. Laser-capture microdissection of human prostatic epithelium for RNA analysis
Sherker et al. Optimal preservation of liver biopsy samples for downstream translational applications
HK40018836A (en) Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue
Biskup et al. Test of the FlashFREEZE unit in tissue samples freezing for biobanking purposes
CN116426480A (zh) 一种人胶质母细胞瘤细胞系y1203及其应用
HK1220481B (en) Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue
US12111239B2 (en) Methods and kits for isolating whole cells from frozen tissues for cell fingerprinting
Shyu et al. Kinetics and functional assay of liver repopulation after human cord blood transplantation
Yamazaki et al. PAXgene-fixed paraffin-embedded sample is applicable to laser capture microdissection with well-balanced RNA quality and tissue morphology
JP2021176279A (ja) 動物組織の解析方法
WO2017160147A1 (en) Organotypic culture system

Legal Events

Date Code Title Description
A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A525

Effective date: 20150928

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170310

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170310

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180117

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180130

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180424

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180727

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20181211

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20190108

R150 Certificate of patent or registration of utility model

Ref document number: 6465857

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250