CA2941929C - Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue - Google Patents
Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue Download PDFInfo
- Publication number
- CA2941929C CA2941929C CA2941929A CA2941929A CA2941929C CA 2941929 C CA2941929 C CA 2941929C CA 2941929 A CA2941929 A CA 2941929A CA 2941929 A CA2941929 A CA 2941929A CA 2941929 C CA2941929 C CA 2941929C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- reagent
- cells
- chelator
- tag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Physiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361798627P | 2013-03-15 | 2013-03-15 | |
| US61/798,627 | 2013-03-15 | ||
| PCT/US2014/029198 WO2014144682A1 (en) | 2013-03-15 | 2014-03-14 | Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2941929A1 CA2941929A1 (en) | 2014-09-18 |
| CA2941929C true CA2941929C (en) | 2021-02-23 |
Family
ID=51528685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2941929A Active CA2941929C (en) | 2013-03-15 | 2014-03-14 | Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US9113623B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2970878B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6465857B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN105121629B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2941929C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1120801T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2970878T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2684582T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20181352T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE039933T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT2970878T (cg-RX-API-DMAC7.html) |
| PL (1) | PL2970878T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2970878T (cg-RX-API-DMAC7.html) |
| RS (1) | RS57900B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2970878T1 (cg-RX-API-DMAC7.html) |
| SM (1) | SMT201800457T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014144682A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2970878T (lt) | 2013-03-15 | 2018-11-12 | Truckee Applied Genomics, Llc | Vėžio ląstelių chirurginiu būdu pašalintame audinyje gyvybingumo palaikymo būdai ir reagenatai |
| EP3224359B1 (en) | 2014-11-25 | 2023-10-25 | Bio-Rad Laboratories, Inc. | Arginine improves polymerase storage stability |
| CN107333750A (zh) * | 2017-06-11 | 2017-11-10 | 成都吱吖科技有限公司 | 一种长时血液细胞稳定剂 |
| WO2021055170A1 (en) * | 2019-09-17 | 2021-03-25 | Longhorn Vaccines And Diagnostics, Llc | Multipurpose compositions for collecting and transporting biological material |
| WO2022010916A1 (en) * | 2020-07-07 | 2022-01-13 | Truckee Applied Genomics, Llc | Cell preservation reagents and methods of use |
| CN117063915A (zh) * | 2023-08-17 | 2023-11-17 | 镜像绮点(上海)细胞技术有限公司 | 原代肿瘤细胞冻存液 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5409826A (en) * | 1993-06-08 | 1995-04-25 | Coulter Corporation | Preserved, non-infectious control cells prepared by the modulation or modification of normal cells |
| JP2000509018A (ja) * | 1996-03-26 | 2000-07-18 | イーライ・リリー・アンド・カンパニー | 肥満タンパク質製剤 |
| US20010007673A1 (en) | 1999-11-12 | 2001-07-12 | Merrill Seymour Goldenberg | Sustained-release delayed gels |
| US20080064108A1 (en) | 1997-12-10 | 2008-03-13 | Tony Baker | Urine Preservation System |
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| JP2001526051A (ja) | 1997-12-10 | 2001-12-18 | シエラ ダイアグノスティクス，インク． | 体液中のｄｎａを保存するための方法及び試薬 |
| DE60116673T2 (de) * | 2000-12-04 | 2006-08-10 | Lymphotec Inc. | Zellkonservierungsflüssigkeit und verfahren zur zellkonservierung mit dieser flüssigkeit |
| KR20020066778A (ko) | 2001-02-13 | 2002-08-21 | 한국과학기술연구원 | 체내 난흡수 물질의 흡수촉진용 조성물과 제형 및 그의제조방법 |
| WO2008111981A1 (en) | 2007-03-14 | 2008-09-18 | Sierra Molecular Corporation | Compositions, systems, and methods for preservation of macromolecules |
| US20040214203A1 (en) * | 2002-12-12 | 2004-10-28 | Oncotech, Inc. | Genes related to sensitivity and resistance to chemotherapeutic drug treatment |
| US8793895B2 (en) * | 2006-02-10 | 2014-08-05 | Praxair Technology, Inc. | Lyophilization system and method |
| KR20090098957A (ko) | 2006-09-12 | 2009-09-18 | 시에라 몰레큘러 코포레이션 | 카오트로프의 완충용액을 사용하는 핵산을 대상으로 하는 분자분석 간섭의 제거 |
| US8080645B2 (en) * | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| US8652782B2 (en) * | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
| AU2007308865A1 (en) | 2006-10-27 | 2008-05-02 | Sierra Molecular Corporation | Penetratable septum cap |
| EP2094846B8 (en) | 2006-12-13 | 2013-10-16 | Roche Diagnostics GmbH | Use of tde for the isolation of nucleic acids |
| JP2010535013A (ja) | 2007-03-14 | 2010-11-18 | シエラ モレキュラー コーポレイション | 細胞および／または高分子の保存および／または安定化のための組成物、システムおよび方法 |
| CA2705417A1 (en) * | 2007-11-12 | 2009-05-22 | Bipar Sciences, Inc. | Treatment of uterine cancer and ovarian cancer with a parp inhibitor alone or in combination with anti-tumor agents |
| US20100003748A1 (en) * | 2008-07-03 | 2010-01-07 | Tony Baker | Compositions, systems, and methods for stabilization of a cell and/or macromolecule |
| US20110165611A1 (en) | 2008-09-04 | 2011-07-07 | Chun Li | Dual modality detection of apoptosis |
| US9133343B2 (en) | 2009-11-30 | 2015-09-15 | Enzo Biochem, Inc. | Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications |
| CN102318597B (zh) * | 2011-08-19 | 2013-04-03 | 张雪云 | 一种液基细胞保存液组合物及其制备方法 |
| LT2970878T (lt) | 2013-03-15 | 2018-11-12 | Truckee Applied Genomics, Llc | Vėžio ląstelių chirurginiu būdu pašalintame audinyje gyvybingumo palaikymo būdai ir reagenatai |
-
2014
- 2014-03-14 LT LTEP14763797.9T patent/LT2970878T/lt unknown
- 2014-03-14 PT PT14763797T patent/PT2970878T/pt unknown
- 2014-03-14 JP JP2016503010A patent/JP6465857B2/ja active Active
- 2014-03-14 CN CN201480014875.5A patent/CN105121629B/zh active Active
- 2014-03-14 DK DK14763797.9T patent/DK2970878T3/en active
- 2014-03-14 CN CN202011428224.4A patent/CN112806352A/zh active Pending
- 2014-03-14 HU HUE14763797A patent/HUE039933T2/hu unknown
- 2014-03-14 ES ES14763797.9T patent/ES2684582T3/es active Active
- 2014-03-14 HR HRP20181352TT patent/HRP20181352T1/hr unknown
- 2014-03-14 EP EP14763797.9A patent/EP2970878B1/en active Active
- 2014-03-14 EP EP18173516.8A patent/EP3581643A1/en not_active Withdrawn
- 2014-03-14 RS RS20180976A patent/RS57900B1/sr unknown
- 2014-03-14 US US14/211,578 patent/US9113623B2/en active Active
- 2014-03-14 CA CA2941929A patent/CA2941929C/en active Active
- 2014-03-14 SI SI201430839T patent/SI2970878T1/sl unknown
- 2014-03-14 WO PCT/US2014/029198 patent/WO2014144682A1/en not_active Ceased
- 2014-03-14 SM SM20180457T patent/SMT201800457T1/it unknown
- 2014-03-14 PL PL14763797T patent/PL2970878T3/pl unknown
-
2015
- 2015-05-01 US US14/702,643 patent/US9565852B2/en active Active
- 2015-05-14 US US14/712,750 patent/US9445586B2/en active Active
-
2016
- 2016-02-02 US US15/013,541 patent/US9949474B2/en active Active
-
2017
- 2017-02-13 US US15/431,478 patent/US10772318B2/en active Active
-
2018
- 2018-08-23 CY CY181100877T patent/CY1120801T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10772318B2 (en) | Methods and reagents for maintaining the visability of cancer cells in surgically removed tissue | |
| Viertler et al. | A new technology for stabilization of biomolecules in tissues for combined histological and molecular analyses | |
| RU2743169C2 (ru) | Репрезентативная диагностика | |
| Steu et al. | A procedure for tissue freezing and processing applicable to both intra-operative frozen section diagnosis and tissue banking in surgical pathology | |
| CN105684989A (zh) | 一种肝癌pdx标准化模型库 | |
| Bertilsson et al. | A new method to provide a fresh frozen prostate slice suitable for gene expression study and MR spectroscopy | |
| Nechifor-Boilă et al. | The storage period of the formalin-fixed paraffin-embedded tumor blocks does not influence the concentration and purity of the isolated DNA in a series of 83 renal and thyroid carcinomas | |
| Vincek et al. | Methodology for preservation of high molecular-weight RNA in paraffin-embedded tissue: application for laser-capture microdissection | |
| Gillio-Meina et al. | Translational research in pediatrics IV: solid tissue collection and processing | |
| US20100323907A1 (en) | Frozen cell and tissue microarrays | |
| Unhale et al. | Stabilization of tissue specimens for pathological examination and biomedical research | |
| HK40018836A (en) | Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue | |
| HK1220481B (en) | Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue | |
| CN116426480A (zh) | 一种人胶质母细胞瘤细胞系y1203及其应用 | |
| Shankar et al. | Biobanking for cancer research: preservation of tissue integrity–some technical considerations | |
| Liehr | Characterization of archived formalin-fixed/paraffin-embedded or cryofixed tissue, including nucleus extraction | |
| Shao et al. | Frozen tissue preparation for high-resolution multiplex histological analyses of human brain specimens | |
| US12111239B2 (en) | Methods and kits for isolating whole cells from frozen tissues for cell fingerprinting | |
| Pendina et al. | Successive Detection of Telomerase by IHC and Assessment of Telomere Length by Q-FISH in Paucicellular Cumulus Samples from Cumulus-Oocyte Complexes Obtained in Assisted Reproduction Programs | |
| Santos et al. | Influence of external factors on the preservation of human nervous tissue for histological studies | |
| Topal et al. | Heat-Stressed Brains: Epigenetic and Mitochondrial Signatures in Zebrafish | |
| Yamazaki et al. | PAXgene-fixed paraffin-embedded sample is applicable to laser capture microdissection with well-balanced RNA quality and tissue morphology | |
| JP2021176279A (ja) | 動物組織の解析方法 | |
| Krajewski et al. | Image Analysis Algorithms for Immunohistochemical Assessment of Cell Death | |
| HK1259849B (zh) | 代表性診斷 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180723 |