JP6444314B2 - 試料ハンドリングのためのシステムおよびデバイス - Google Patents

試料ハンドリングのためのシステムおよびデバイス Download PDF

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Publication number
JP6444314B2
JP6444314B2 JP2015552774A JP2015552774A JP6444314B2 JP 6444314 B2 JP6444314 B2 JP 6444314B2 JP 2015552774 A JP2015552774 A JP 2015552774A JP 2015552774 A JP2015552774 A JP 2015552774A JP 6444314 B2 JP6444314 B2 JP 6444314B2
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basket
tray
well
wall
side wall
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JP2016505855A5 (enExample
JP2016505855A (ja
Inventor
ロスティスラフ チェルノモルスキー，
ロスティスラフ チェルノモルスキー，
ニコラス ゲール，
ニコラス ゲール，
サム チチョン，
サム チチョン，
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B01L2300/0618—Holders integrated in container to position an object for removable separation walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Robotics (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2015552774A 2013-01-11 2014-01-09 試料ハンドリングのためのシステムおよびデバイス Active JP6444314B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361751508P 2013-01-11 2013-01-11
US61/751,508 2013-01-11
PCT/US2014/010887 WO2014110267A1 (en) 2013-01-11 2014-01-09 Systems and devices for sample handling

Publications (3)

Publication Number Publication Date
JP2016505855A JP2016505855A (ja) 2016-02-25
JP2016505855A5 JP2016505855A5 (enExample) 2017-10-12
JP6444314B2 true JP6444314B2 (ja) 2018-12-26

Family

ID=50001328

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015552774A Active JP6444314B2 (ja) 2013-01-11 2014-01-09 試料ハンドリングのためのシステムおよびデバイス

Country Status (17)

Country Link
US (2) US9632101B2 (enExample)
EP (1) EP2943280B1 (enExample)
JP (1) JP6444314B2 (enExample)
KR (1) KR101995767B1 (enExample)
CN (2) CN104936698B (enExample)
AU (1) AU2014205375B2 (enExample)
BR (1) BR112015016544B1 (enExample)
CA (1) CA2896092C (enExample)
ES (1) ES2872389T3 (enExample)
IL (1) IL239498B (enExample)
MX (1) MX357979B (enExample)
MY (1) MY174743A (enExample)
NZ (2) NZ739844A (enExample)
RU (1) RU2663754C2 (enExample)
SG (2) SG11201504802WA (enExample)
WO (1) WO2014110267A1 (enExample)
ZA (1) ZA201504490B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110308336A1 (en) * 2010-06-16 2011-12-22 Identigene, L.L.C. Methods and apparatus for specimen collection and transport
CA2896092C (en) 2013-01-11 2019-07-16 Regeneron Pharmaceuticals, Inc. Systems and devices for sample handling
EP3411150A2 (en) 2016-02-04 2018-12-12 Massachusetts Institute of Technology Modular organ microphysiological system with integrated pumping, leveling, and sensing
WO2017151098A1 (en) * 2016-02-29 2017-09-08 Hewlett-Packard Development Company, L.P. Liquid directing sample container
US11142738B2 (en) * 2016-10-25 2021-10-12 The Regents Of The University Of California Sieve system and methods for cell media exchange
US12655379B2 (en) * 2017-01-18 2026-06-16 Shinko Chemical Co., Ltd. Device for evaluation of chemical substance and method for evaluation of chemical substance
KR102370055B1 (ko) 2018-01-08 2022-03-03 일루미나, 인코포레이티드 반도체-기반 검출을 사용하는 고-처리율 서열분석용 시스템 및 디바이스
NL2020621B1 (en) 2018-01-08 2019-07-15 Illumina Inc Multiplexing of an active sensor detector using structured illumination
US11378544B2 (en) * 2018-01-08 2022-07-05 Illumina, Inc. High-throughput sequencing with semiconductor-based detection
US11749437B2 (en) 2018-05-01 2023-09-05 Massachusetts Institute Of Technology Pumps and hardware for organ-on-chip platforms
KR102133908B1 (ko) 2018-10-17 2020-07-14 주식회사 아이센스 원심분리와 자동분석이 가능한 카트리지
CN113302278A (zh) * 2018-11-16 2021-08-24 爱新诺有限公司 实验室器具和用于在细胞培养过程中处理实验室器具的处理系统
WO2020098957A1 (en) 2018-11-16 2020-05-22 Aixinno Limited A process module for an automated biology system
EP3881082B1 (en) 2018-11-16 2024-03-13 Aixinno Limited Module for an automated biology laboratory system with an interface to transfer microplates or lab-ware
EP3902632A1 (en) * 2018-12-28 2021-11-03 Astraveus Device and method for handling a particle suspension
WO2020225420A1 (en) * 2019-05-08 2020-11-12 Scienion Ag Assay plate with nano-vessels and sample recovery assembly
CN114008462B (zh) * 2019-06-19 2026-01-16 生命技术公司 试剂容器和使用方法
US11534766B2 (en) * 2019-09-06 2022-12-27 Rushabh Instruments, Llc Immuno histo chemistry tissue processing system
US20230002713A1 (en) * 2019-11-19 2023-01-05 Jennifer Hui-Chun Ho Cell culture system and methods of using the same
KR102360717B1 (ko) * 2020-02-10 2022-02-10 주식회사 아이센스 반사형 포토센서를 이용한 전혈, 혈장 및 미흡입 자동구분방법
KR102145842B1 (ko) * 2020-03-06 2020-08-19 주식회사 퀀타매트릭스 정확한 관찰이 용이한 신속한 세포배양검사 장치
KR102127765B1 (ko) * 2020-03-06 2020-06-29 주식회사 퀀타매트릭스 고형화된 유체의 이탈을 방지할 수 있는 신속한 세포배양검사 장치
KR102132635B1 (ko) * 2020-03-16 2020-07-10 주식회사 퀀타매트릭스 유체막 두께가 일정한 신속한 세포배양검사 장치
US11732964B2 (en) * 2020-04-15 2023-08-22 Navinta Iii Inc Lyophilization promoting element
EP4232553A1 (en) * 2020-10-22 2023-08-30 Molecular Devices (Austria) GmbH Microplates for automating organoid cultivation
US11879117B2 (en) * 2020-11-10 2024-01-23 C.C. Imex Gel tray for bacteria transformation lab
US11879118B2 (en) * 2020-11-10 2024-01-23 C.C. Imex Gel tray for bacteria transformation lab
CN113075206A (zh) * 2021-02-22 2021-07-06 青岛市妇女儿童医院 一种基于生殖医学科男性精子的检验装置
PL4056272T3 (pl) * 2021-03-11 2026-05-25 Euroimmun Medizinische Labordiagnostika Ag Urządzenie do przytrzymywania każdorazowych elementów membranowych w każdorazowych wgłębieniach płytki wielodołkowej
US20250313789A1 (en) * 2022-05-20 2025-10-09 Public University Corporation Nagoya City University Cell culture substrate and cell culture method
CN115895885B (zh) * 2022-12-02 2026-07-28 安徽省立医院(中国科学技术大学附属第一医院) 一种机械辅助解冻胚胎的装置及方法
EP4763335A1 (en) * 2024-12-20 2026-06-24 Koninklijke Philips N.V. Systems and methods for testing biological material
WO2026131215A1 (en) 2024-12-18 2026-06-25 Koninklijke Philips N.V. Systems and methods for testing biological material
CN120424767A (zh) * 2025-07-09 2025-08-05 中国农业科学院果树研究所 生物细胞培养容器

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828386A (en) * 1987-06-19 1989-05-09 Pall Corporation Multiwell plates containing membrane inserts
US5141718A (en) * 1990-10-30 1992-08-25 Millipore Corporation Test plate apparatus
US5534227A (en) * 1995-06-05 1996-07-09 Becton, Dickinson And Company Thermoform dish insert
US5643228A (en) 1995-11-13 1997-07-01 Uresil Corporation Catheter
JP3201965B2 (ja) * 1995-12-28 2001-08-27 アロカ株式会社 試薬処理用の試料容器及び生物組織の処理装置
US5976470A (en) 1998-05-29 1999-11-02 Ontogen Corporation Sample wash station assembly
JP4471648B2 (ja) * 2001-05-30 2010-06-02 バイオレックス・セラピューティクス インコーポレイテッド 高スループットスクリーニングのためのプレートおよび方法
US20040043398A1 (en) * 2002-04-15 2004-03-04 Demetrio Sanchez-Martinez Use of the multipin platform as anchor device
US6943009B2 (en) * 2002-05-15 2005-09-13 Corning Incorporated Multi-well assembly for growing cultures in-vitro
EP1547686A1 (en) * 2003-12-22 2005-06-29 F.Hoffmann-La Roche Ag Microtiter plate, system and method for processing samples
JP2008529825A (ja) * 2005-01-20 2008-08-07 スリーエム イノベイティブ プロパティズ カンパニー 構造化ポリマーフィルムおよびその製造方法
FR2881434B1 (fr) * 2005-02-02 2007-05-11 Coletica Sa Dispositif de support de culture de cellules
US20060286003A1 (en) * 2005-06-16 2006-12-21 Desilets Kenneth G Multi-well filter plate with shifted wells and U-bottom receiver plate
WO2009012808A1 (en) * 2007-07-23 2009-01-29 Tecan Trading Ag Collection/extraction container for biological material in forensic samples
US8877141B2 (en) 2007-09-06 2014-11-04 Qiagen Sciences Llc System for preparing arrays of biomolecules
US7858371B2 (en) * 2007-09-26 2010-12-28 Weyerhaeuser Nr Company Method of separating embryo suspension mass
WO2009102466A1 (en) * 2008-02-14 2009-08-20 The General Hospital Corporation Well-based flow system for cell culture
GB0913258D0 (en) * 2009-07-29 2009-09-02 Dynex Technologies Inc Reagent dispenser
WO2011037920A2 (en) 2009-09-23 2011-03-31 The Johns Hopkins University Sample processing device
CA2896092C (en) 2013-01-11 2019-07-16 Regeneron Pharmaceuticals, Inc. Systems and devices for sample handling

Also Published As

Publication number Publication date
CN107497506B (zh) 2020-04-10
US9896653B2 (en) 2018-02-20
CN104936698B (zh) 2017-09-12
NZ709321A (en) 2018-02-23
MX2015008976A (es) 2015-09-29
CA2896092A1 (en) 2014-07-17
SG11201504802WA (en) 2015-07-30
BR112015016544A2 (pt) 2017-07-11
SG10201706279PA (en) 2017-09-28
BR112015016544A8 (pt) 2019-10-29
MY174743A (en) 2020-05-13
NZ739844A (en) 2020-07-31
HK1212285A1 (en) 2016-06-10
US9632101B2 (en) 2017-04-25
JP2016505855A (ja) 2016-02-25
WO2014110267A1 (en) 2014-07-17
US20170191014A1 (en) 2017-07-06
ES2872389T3 (es) 2021-11-02
CN104936698A (zh) 2015-09-23
IL239498A0 (en) 2015-08-31
RU2663754C2 (ru) 2018-08-09
MX357979B (es) 2018-08-01
CN107497506A (zh) 2017-12-22
AU2014205375B2 (en) 2018-03-08
IL239498B (en) 2018-03-29
ZA201504490B (en) 2016-05-25
AU2014205375A1 (en) 2015-07-09
KR20150104569A (ko) 2015-09-15
EP2943280A1 (en) 2015-11-18
RU2015132612A (ru) 2017-02-16
CA2896092C (en) 2019-07-16
US20140196550A1 (en) 2014-07-17
EP2943280B1 (en) 2021-05-12
BR112015016544B1 (pt) 2022-01-11
KR101995767B1 (ko) 2019-07-03

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