JP6435127B2 - Melting equipment - Google Patents

Description

  The present invention relates to a dissolution apparatus for dissolving a powder drug for dialysis to obtain a stock solution for dialysis.

  Dialysis fluids used for the treatment of patients with renal failure in hospitals are generally divided into bicarbonate and acetic acid. Of these, bicarbonate-based dialysate does not contain sodium bicarbonate (hereinafter referred to as “bicarbonate”). It is prepared by mixing water with two types of drugs, called A agent and sodium bicarbonate (hereinafter referred to as B agent). In recent years, from the viewpoint of improving transportability, attempts have been made to dissolve these A agent and B agent powder (hereinafter referred to as “dialysis powder drug”) before dialysis treatment time. As for the solution (especially B agent), the concentration was likely to decrease over time, and it was difficult to prepare a large amount of solution.

  For this reason, dissolution work is required for each dialysis treatment, and various dissolution apparatuses for dissolution have been proposed. For example, Patent Document 1 discloses a melting apparatus provided with two melting tanks. With this configuration, after completion of dialysis, a powder drug for dialysis is put in advance in one dissolution tank for the next dialysis, and the other dissolution tank is washed and disinfected until the next dialysis is started. It can be carried out. Further, during the dialysis, while the dialysate stock solution is supplied from one dissolution tank to the artificial dialysate supply device, the powder drug for dialysis can be additionally dissolved in the other dissolution tank.

JP 2001-9028 A

  However, in the above prior art, it was difficult to determine the suitability of the amount of the dialysis powder drug charged in the dissolution tank relative to the amount of water supplied in the dissolution tank. When an amount of powder drug for dialysis is charged, there is a problem that an undiluted stock solution for dialysis is generated. In addition, it may be possible to measure the conductivity of the dialysis stock solution and determine the suitability of the dosage of the dialysis powder drug based on the measured value. Therefore, if it was determined that the input amount was inappropriate, the agitation generation work had to be performed again.

  The present invention has been made in view of such circumstances, and it is an object of the present invention to provide a dissolution apparatus that can accurately determine the suitability of the amount of the powdered dialysis drug charged into the dissolution tank with a simple configuration. .

The invention described in claim 1 is a dissolution apparatus for dissolving a dialysis powder drug to obtain a dialysis stock solution, a dissolution tank capable of containing the dialysis powder drug, and the dialysis powder drug in the dissolution tank. Water supply line for supplying water for dissolution, stirring means for stirring the solution in the dissolution tank, and the level of water or solution supplied in the dissolution tank can be detected continuously and in real time Based on the liquid level detected by the liquid level detection means in a state where water and the powder drug for dialysis are contained in the dissolution tank and before stirring by the stirring means , And determining means capable of determining whether or not the amount of the dialysis powder drug charged in the dissolution tank relative to the amount of water supplied in the dissolution tank is appropriate.

  According to a second aspect of the present invention, there is provided the dissolution apparatus according to the first aspect, wherein the determining means is configured such that the amount of the powdered dialysis drug charged relative to the amount of water supplied into the dissolution tank is appropriate. The theoretical value of the liquid level is compared with the measured value of the liquid level detected by the liquid level detecting means, and the water supplied into the dissolution tank is calculated from the difference between the theoretical value of the liquid level and the measured value. It is possible to determine whether or not the amount of the powder drug for dialysis charged into the dissolution tank with respect to the amount is appropriate.

  According to a third aspect of the present invention, there is provided the dissolution apparatus according to the second aspect, wherein the determination means is configured to determine the amount of water supplied into the dissolution tank based on a difference between a theoretical value and an actual measurement value of the liquid level. It is characterized in that the excess or deficiency of the powder drug for dialysis put in the inside can be calculated.

  According to a fourth aspect of the present invention, in the dissolution apparatus according to any one of the first to third aspects, the determination unit is set so that the stirring by the stirring unit is performed for a predetermined time, and after the predetermined time has elapsed. When it is determined that the amount of the powder drug for dialysis charged in the dissolution tank relative to the amount of water supplied in the dissolution tank is not appropriate, the fact is notified.

The invention according to claim 5 comprises an input means for inputting the amount of the powder drug for dialysis charged into the dissolution tank in the dissolution apparatus according to any one of claims 1 to 4 , The determination means can determine an appropriate amount of the dialysis powder drug based on the input value input by the input means and the liquid level detected by the liquid level detection means.

A sixth aspect of the present invention is the lysis device according to any one of the first to fifth aspects, wherein the dialysis device is generated in the dissolution tank based on the liquid level detected by the liquid level detecting means. The volume of the stock solution can be calculated.

According to invention of Claim 1, based on the liquid level detected by the liquid level detection means which can detect the liquid level of the water or solution supplied in the dissolution tank continuously and in real time, and the liquid level detection means And a judgment means that can judge the suitability of the amount of the dialysis powder drug charged in the dissolution tank relative to the amount of water supplied in the dissolution tank, so that the dialysis powder drug charged in the dissolution tank Appropriateness of the quantity can be accurately determined with a simple configuration.
In addition, when water and dialysis powder medicine are contained in the dissolution tank, and before stirring by the stirring means, the dialysis use that has been put into the dissolution tank with respect to the amount of water supplied into the dissolution tank by the judgment means Since the appropriateness of the amount of powdered drug is determined, it is possible to reliably determine the appropriateness of the amount of powdered drug for dialysis prior to the production of the dialysis stock solution. In addition, workability can be improved because it is not necessary to repeat the stirring operation.

  According to the invention of claim 2, the determination means includes the theoretical value of the liquid level when the amount of the powdered dialysis drug charged with respect to the amount of water supplied into the dissolution tank is appropriate, and the liquid level. Compared with the measured value of the liquid level detected by the detection means, the dialysis powder charged in the dissolution tank with respect to the amount of water supplied into the dissolution tank from the difference between the theoretical value and the measured value of the liquid level Since the suitability of the amount of the drug can be determined, the suitability of the amount of the powdered dialysis drug charged can be determined with higher accuracy.

  According to the invention of claim 3, the judging means is based on the difference between the theoretical value of the liquid level and the actually measured value, the excess or deficiency of the powder drug for dialysis put into the dissolving tank relative to the amount of water supplied into the dissolving tank. Since the amount can be calculated, in addition to the appropriateness of the amount of powdered dialysis drug added, it is possible to grasp the shortage or excess, and how much dialysis powdered drug or water should be added to make it appropriate Can be informed.

  According to the invention of claim 4, it is set so that the stirring by the stirring means is performed for a predetermined time, and after the predetermined time has elapsed, the water is supplied into the dissolution tank with respect to the amount of water supplied into the dissolution tank by the determination means. If it is determined that the amount of the dialysis powder drug is not appropriate, a notification to that effect will be sent, and the dialysis stock solution with an inappropriate dialysis powder drug amount will be sent to the dialysis treatment device side. Can be prevented.

According to the invention of claim 5 , the input means for inputting the amount of the dialysis powder medicine charged into the dissolution tank is provided, and the judging means is the input value and liquid level detecting means inputted by the input means. Therefore, it is possible to determine the appropriate amount of the dialysis powder drug on the basis of the liquid level detected by the above, so that the dialysis powder drug can be surely grasped by the dissolving device. It is possible to accurately determine whether or not the dose of the medicine is appropriate.

According to the invention of claim 6 , since the volume of the dialysis stock solution generated in the dissolution tank can be calculated based on the liquid level detected by the liquid level detection means, the liquid level detection means was inserted. In addition to functioning as a means for determining the suitability of the amount of the powder drug for dialysis, it can function as a means for calculating the volume of the dialysis stock solution produced in the dissolution tank.

The top view and front view which show the melt | dissolution apparatus which concerns on embodiment of this invention Schematic diagram showing the internal configuration of the dissolution apparatus Flow chart showing control contents in the dissolution apparatus The flowchart which shows the control content of the melt | dissolution apparatus which concerns on other embodiment of this invention.

Hereinafter, embodiments of the present invention will be specifically described with reference to the drawings.
The dissolution apparatus according to the present embodiment dissolves a dialysis powder drug to obtain a dialysis stock solution. As shown in FIGS. 1 and 2, a dissolution tank 2 and an auxiliary dissolution tank that can accommodate a dialysis powder drug 3, the water supply lines L1 and L2 for supplying water for dissolving the dialysis powder drug to each of the dissolution tank 2 and the auxiliary dissolution tank 3, and the liquid in the dissolution tank 2 and the auxiliary dissolution tank 3 are stirred. Mainly composed of agitation means 4 and 5, a liquid level detection means 6, a determination means 7 having a storage means 8 and a calculation means 9, an input means 10, and a display means 11.

  The dissolution tank 2 has a storage space in which a powder drug for dialysis composed of either one of sodium bicarbonate (A agent) or sodium bicarbonate (B agent) can be charged, and a water supply source A A water supply line L1 extending from is connected. The water supply line L1 is provided with a valve V1 composed of an electromagnetic valve or the like, and water can be supplied into the dissolution tank 2 by opening the valve V1. Thus, after supplying a predetermined amount of water from the water supply source A into the dissolution tank 2 and storing it, a predetermined amount of the powdered dialysis drug for the amount of the water is supplied to the dissolution tank 2. By adding and stirring, a dialysis stock solution having a predetermined amount and a predetermined concentration can be obtained.

  The auxiliary dissolution tank 3 has a space where a dialysis powder drug of the same type as the dialysis powder charged in the dissolution tank 2 can be charged, and a water supply line L2 extending from the stirring line L3 of the dissolution tank 2 is connected. Has been. The water supply line L2 is provided with a valve V2 composed of an electromagnetic valve or the like. By opening the valve V2, water can be supplied from the dissolution tank 2 into the auxiliary dissolution tank 3. The auxiliary dissolution tank 3 is a tank having a relatively small capacity compared to the dissolution tank 2, and is connected to the dissolution tank 2 through an overflow line L5.

  Accordingly, the powder drug for dialysis is put in advance in the auxiliary dissolution tank 3, and a sufficient amount of water determined in the dissolution tank 2 is supplied at the time of treatment, and stirring is performed while supplying water from the water supply line L2. The valve V3 disposed in L3 is closed, and the solution is sent to the dissolution tank 2 via the overflow line L5, so that both the dissolution tank 2 and the auxiliary dissolution tank 3 have a predetermined amount and a predetermined amount. Concentrate stock solution for dialysis is produced. First, the dialysis stock solution in the dissolution tank 2 is sent to the dialysis treatment device side (dialysis solution supply device etc.), and when the dissolution tank 2 is empty, the dialysis stock solution in the auxiliary dissolution tank 3 is continued. The liquid can be sent. In addition, while the undiluted solution for dialysis in the auxiliary dissolving tank 3 is being fed, the undiluted solution for dialysis can be generated by the dissolving tank 2 alone by introducing and dissolving the dialysis powder drug in the dissolving tank 2. it can.

  Therefore, by providing the auxiliary dissolution tank 3, before treatment (the night before the treatment, etc.), the dissolution tank 2 is cleaned or disinfected with the powder for dialysis charged in the auxiliary dissolution tank 3. It can function as a reservoir during treatment. Moreover, the powder medicine for dialysis applied to this embodiment is packed in a dissolution bag every predetermined amount, and the operator breaks the dissolution bag, and the powder medicine for dialysis in the dissolution tank 2 or the auxiliary dissolution tank. 3 is to be input.

  The agitation means 4 is for agitating the liquid (solution) accommodated in the dissolution tank 2, and in the present embodiment, comprises a nozzle connected to the tip of the circulation line L3. The circulation line L3 extends from the bottom surface of the dissolution tank 2, and includes a circulation flow path connected to stirring means 4 disposed in the dissolution tank 2, and a pump P1 in the middle of the flow path. Is arranged. Thus, when the pump P1 is driven, the liquid in the dissolution tank 2 can be ejected from the stirring means 4 and circulated, so that the liquid in the dissolution tank 2 can be stirred.

  The stirring means 5 is for stirring the liquid (solution) stored in the auxiliary dissolution tank 3, and in the present embodiment, is composed of a nozzle connected to the tip of the water supply line L2. The water supply line L <b> 2 extends from the stirring line L <b> 3 of the dissolution tank 2, and the tip thereof is connected to the stirring means 5 disposed in the auxiliary dissolution tank 3. Then, when a sufficient amount of water set in the dissolution tank 2 is supplied, and then the valve V2 is opened and the pump P1 is driven, the liquid in the dissolution tank 2 is ejected from the stirring means 5, and the inside of the auxiliary dissolution tank 3 In addition to stirring the dialysis powder drug, the valve V3 disposed in the stirring line L3 is closed, and the solution is also fed to the dissolution tank 2 via the overflow line L5. Stirring and dissolution are performed both in the tank 3.

  In addition, although the stirring means 4 and 5 which concern on this embodiment consist of the nozzle connected to the front-end | tip of the circulation line L3 which consists of a circulation flow path, and the water supply line L2, the dissolution tank 2 and the auxiliary dissolution tank 3 are used. As long as it can stir the solution inside, it may be in another form (for example, an impeller that can be rotationally driven in the dissolution tank 2 and the auxiliary dissolution tank 3). Further, shower means capable of ejecting liquid in a shower shape may be provided on the upper part of the dissolution tank 2 and the auxiliary dissolution tank 3, and the shower means may be connected to the ends of the circulation line L3 and the water supply line L2.

  The liquid level detection means 6 is composed of a sensor disposed in the dissolution tank 2 and can continuously and in real time detect the liquid level of the water or solution supplied into the dissolution tank 2. The liquid level detection means 6 according to the present embodiment includes a displacement part 6a extending in the vertical direction in the accommodation space of the dissolution tank 2, and a displacement part 6a while floating on the liquid level of the liquid accommodated in the dissolution tank 2. The magnetostrictive linear displacement sensor has a floating means 6b that can move up and down along the surface of the liquid. By detecting the position of the floating means 6b relative to the displacement portion 6a continuously and in real time, Can be detected.

  The liquid level detection means 6 may be either a contact type or a non-contact type as long as the liquid level of the water or solution supplied into the dissolution tank 2 can be detected continuously and in real time. In addition to the magnetostrictive linear displacement sensor using the floating means as in the present embodiment, an ultrasonic sensor or the like may be used. In the present embodiment, the liquid level detecting means 6 is disposed only in the dissolution tank 2, but it may be disposed in the auxiliary dissolution tank 3 together with the dissolution tank 2.

  Moreover, the input means 10 and the display means 11 are arrange | positioned at the housing | casing part of the melting apparatus 1 which concerns on this embodiment. The input means 10 is constituted by an operation switch or a touch panel that can be input by an operator. In this embodiment, the input means 10 indicates the amount of the dialysis powder drug introduced into the dissolution tank 2 or the auxiliary dissolution tank 3. It can be entered. The display means 11 is composed of a liquid crystal monitor or the like, and is capable of performing various displays relating to the melting operation.

  Here, the dissolution apparatus 1 according to the present embodiment includes a determination means 7 electrically connected to the liquid level detection means 6, the input means 10, the display means 11, and the like. The determination means 7 comprises, for example, a microcomputer or the like, and based on the liquid level detected by the liquid level detection means 6, dialysis charged into the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2. It is configured to be able to judge the suitability of the amount of powder drug for use.

  The determination means 7 according to the present embodiment is determined in advance when the amount of the dialysis powder drug added to the amount of water supplied into the dissolution tank 2 is appropriate (that is, predetermined for a predetermined amount of water). The theoretical value of the liquid level in the case where the prescribed amount of powdered drug for dialysis is added) and the actual value of the liquid level detected by the liquid level detection means 6 are compared, and the theoretical value and the actual value of the liquid level are compared. From the difference between the two values, it is possible to determine whether or not the amount of the powder drug for dialysis charged into the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2 can be judged. At the same time, by determining whether or not the amount of the dialysis powder drug charged in the dissolution tank 2 with respect to the amount of water supplied in the dissolution tank 2 was determined, the “dialysis charged in the dissolution tank 2” It is also possible to determine whether the amount of water supplied into the dissolution tank 2 with respect to the amount of the powder medicine for use is appropriate.

  Specifically, the determination means 7 determines in advance when the amount of the dialysis powder drug added to the amount of water supplied into the dissolution tank 2 is appropriate (that is, predetermined for a predetermined amount of water). Storage means 8 for storing the theoretical value of the liquid level when the prescribed amount of powdered dialysis drug is charged, and the theoretical value of the liquid level stored in the storage means 8 and the liquid level detection means 6. And a calculating means 9 for comparing the actual value of the detected liquid level (for example, subtracting or calculating the ratio between the theoretical value of the liquid level and the actual value of the liquid level). If the measured value is substantially the same, it is determined that the amount of the dialysis powder drug to be supplied relative to the amount of water supply is appropriate.

  On the other hand, in the present embodiment, the input means 10 inputs the amount of the dialysis powder medicine charged into the dissolution tank 2 (specifically, the number of dissolution bags used). Based on the inputted input value and the liquid level detected by the liquid level detecting means 6, it is possible to determine the appropriate amount of the dialysis powder drug to be charged. That is, the judging means 7 grasps the input amount of the dialysis powder drug (the number of dissolving bags × the capacity of one dissolving bag) from the input value (the number of dissolving bags) input by the input means 10 and inputs the input. The value and the amount of water supply are compared to determine “propriety”. Thereby, it is possible to make the dissolving device surely grasp the input amount of the powder drug for dialysis, and to accurately determine the suitability of the input amount of the powder drug for dialysis.

  Then, when the actual measurement value of the liquid level is larger than the theoretical value of the liquid level, the judging means 7 indicates that the amount of the dialysis powder drug to be supplied with respect to the water supply amount is excessive (more than the dialysis powder drug to be added). In addition, if the measured value of the liquid level is smaller than the theoretical value of the liquid level, it is determined that the amount of the dialysis powder medicine to be supplied is insufficient (less than the dialysis powder medicine to be added), and the water supply amount It is determined that the amount of the dialysis powder drug is not “appropriate”.

  Furthermore, the calculation means 9 of the judgment means 7 according to the present embodiment is for dialysis used in the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2 from the difference between the theoretical value and the actual measurement value of the liquid level. An excessive or insufficient amount (insufficient or excessive amount) of the powder drug is calculated. In this way, in addition to the appropriateness of the amount of the dialysis powder drug introduced, it is possible to grasp the shortage or excess amount, and to inform the extent to which the dialysis powder drug or water should be added to make it appropriate. it can.

  Furthermore, the calculation means 9 of the determination means 7 according to the present embodiment can calculate the volume of the dialysis stock solution generated in the dissolution tank 2 based on the liquid level detected by the liquid level detection means 6. It is configured. By calculating the volume of the dialysis stock solution produced in the dissolution tank 2, for example, it can be determined whether or not the dialysis stock solution is sufficient until the dialysis treatment is completed. Therefore, in order to make the liquid level detection means 6 function as a means for determining the suitability of the amount of the charged dialysis powder drug, in order to calculate the volume of the dialysis stock solution generated in the dissolution tank 2. It can function as a means.

  In addition, the dissolving device 1 according to the present embodiment is set so that the stirring by the stirring means 4 is performed for a predetermined time, and with respect to the amount of water supplied into the dissolving tank 2 by the judging means 7 after the predetermined time has elapsed. When it is determined that the amount of the powder drug for dialysis charged into the dissolution tank 2 is not appropriate, a notification to that effect is given. The notification may be, for example, a notification by sound, a warning sound such as a buzzer, in addition to the display by the display unit 11.

  Furthermore, in the present embodiment, the amount of water supplied into the dissolution tank 2 by the determination means 7 before the stirring by the stirring means 4 is performed in a state where water and the dialysis powder drug are contained in the dissolution tank 2. It is configured to determine whether or not the amount of the dialysis powder drug charged into the dissolution tank 2 is appropriate, and the storage means 8 stores the liquid level when the dialysis powder drug is not dissolved in water (undissolved). Liquid level at time) is stored as “theoretical value of liquid level”.

Next, the control content of the dissolution apparatus 1 according to the present embodiment (production of a dialysis stock solution using the dissolution tank 2 alone) will be described based on the flowchart of FIG.
First, the operator inputs (S1) the amount of the dialysis powder drug to be charged (that is, the number of dissolution bags to be used) by the input means 10 and then opens the valve V1 so that the inside of the dissolution tank 2 is opened. Is supplied with a predetermined amount of water (S2), and the amount of dialysis powder drug input to the input means 10 (dissolution bag) is charged into the dissolution tank 2 (S3).

  Then, the liquid level detection means 6 detects the liquid level immediately after the introduction of the dialysis powder medicine (S4), and based on the detected liquid level, the dissolution tank for the amount of water supplied into the dissolution tank 2 2 is judged by the judging means 7 (S5). If it is determined in S5 that the amount of the dialysis powder drug is appropriate, the process proceeds to S6, where the pump P1 is driven to actuate the agitating means 4 to agitate the water in the dissolution tank 2 and the dialysis powder drug. Then, a stock solution for dialysis having a predetermined concentration is prepared by dissolving them.

  On the other hand, if it is determined in S5 that the amount of the powder drug for dialysis is not appropriate, the process proceeds to S7, in which it is determined whether or not the liquid level detected by the liquid level detection means 6 is lower than the standard, and it is determined that the level is low. Then, since it can be determined that the input amount of the powder drug for dialysis is insufficient, the process proceeds to S8, the shortage amount is calculated by the calculation means 9, and an additional input amount (added) corresponding to the shortage amount is added. The number of dissolution bags) is displayed on the display means 11 to instruct additional charging.

  Then, in S9, the operator waits for an input operation, and when the input operation is performed, it is determined whether or not the input is an instruction to continue the work (S10). If it is determined in S10 that an instruction to continue the operation has been input, the process proceeds to S3, and the additional charging amount of the dialysis powder drug displayed on the display means 11 is input to the dissolution tank 2. If it is determined in S10 that an instruction not to continue the operation has been input, the process proceeds to S11 and the solution in the dissolution tank 2 is discarded.

  If it is determined in S7 that the liquid level detected by the liquid level detection means 6 is higher than the specified level, it can be determined that the amount of the dialysis powder drug input is excessive (the amount of water supply is insufficient). Therefore, the process proceeds to S12, where the calculation means 9 calculates the excess amount, and the display means 11 displays the erroneous input amount (the number of dissolution bags used in error) corresponding to the excess amount. Then, in S13, the operator waits for an input operation. When the input operation is performed, it is determined whether or not the input is an instruction to continue the work (S14).

  If it is determined in S14 that an instruction to continue the operation has been input, the process proceeds to S15, where the input value is changed to the input amount of dialysis powder drug (number of dissolution bags) suitable for the amount of water supply, and to S2. Will return. If it is determined in S14 that an instruction not to continue the operation has been input, the process proceeds to S16 and the solution in the dissolution tank 2 is discarded. Thus, before the stirring by the stirring means 4, the control for determining the suitability of the amount of the dialysis powder drug introduced into the dissolution tank 2 relative to the amount of water supplied into the dissolution tank 2 by the determination means 7. It will end.

  According to the above embodiment, based on the liquid level detection means 6 capable of continuously and in real time detecting the liquid level of the water or solution supplied into the dissolution tank 2 and the liquid level detected by the liquid level detection means 6. And a determination means 7 for determining whether or not the amount of the powdered dialysis drug charged into the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2 is provided. Appropriateness of the amount of the powder drug for dialysis can be accurately determined with a simple configuration.

  In particular, the determination means 7 according to the present embodiment includes the theoretical value of the liquid level when the amount of the powdered dialysis drug charged with respect to the amount of water supplied into the dissolution tank 2 is appropriate, and the liquid level. The actual value of the liquid level detected by the detecting means is compared, and the dialysis charged into the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2 from the difference between the theoretical value and the actual measurement value of the liquid level. Therefore, the suitability of the amount of the powdered dialysis drug charged can be judged with higher accuracy.

  Further, in the present embodiment, the stirring by the stirring means 4 is set to be performed for a predetermined time, and after the predetermined time has elapsed, the inside of the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2 by the determination means 7 If it is determined that the amount of the dialysis powder drug added to the dialysis agent is not appropriate, a notification to that effect will be made. It is possible to prevent the liquid from being fed to an apparatus or the like. The predetermined time for stirring may be stored in advance or may be input by the input means 10.

  Furthermore, in this embodiment, the water supplied in the dissolution tank 2 by the determination means 7 before the stirring by the stirring means 4 is performed in a state where water and the powder drug for dialysis are accommodated in the dissolution tank 2. Since the appropriateness of the amount of the dialysis powder drug charged into the dissolution tank 2 with respect to the amount is determined, it is possible to reliably determine the appropriateness of the dialysis powder drug input before the dialysis stock solution is generated. Even if it is determined that the amount is not appropriate, the workability can be improved because it is not necessary to repeat the stirring operation.

  Next, the control content of the melting apparatus 1 according to another embodiment of the present invention will be described based on the flowchart of FIG. Here, in this embodiment, after the stirring by the stirring means 4, it is determined whether or not the amount of the dialysis powder drug introduced into the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2 by the determination means 7 is determined. The storage means 8 stores the liquid level when the powder drug for dialysis is not completely dissolved in water (the liquid level at the time of dissolution) as “theoretical value of the liquid level”.

  First, the operator inputs (S1) the amount of the dialysis powder drug to be charged (that is, the number of dissolution bags to be used) by the input means 10 and then opens the valve V1 so that the inside of the dissolution tank 2 is opened. Is supplied with a predetermined amount of water (S2), and the amount of dialysis powder drug input to the input means 10 (dissolution bag) is charged into the dissolution tank 2 (S3). Then, in S4, the pump P1 is driven to operate the stirring means 4, and the solution (dialysis stock solution) is prepared by stirring and dissolving the water and the powder drug for dialysis in the dissolution tank 2 for a predetermined time.

  Thereafter, the liquid level detecting means 6 detects the liquid level after the stirring of the water and the powder drug for dialysis (S5), and the amount of water supplied into the dissolution tank 2 based on the detected liquid level. The determination means 7 determines whether or not the amount of the dialysis powder drug charged into the dissolution tank 2 is appropriate (S6). If it is determined in S6 that the amount of the powder drug for dialysis is appropriate, a series of stirring and dissolving operations are completed.

  On the other hand, when it is determined in S6 that the amount of the powder drug for dialysis is not appropriate, the process proceeds to S7, where it is determined whether or not the liquid level detected by the liquid level detection means 6 is lower than the specified level. It is determined whether or not the concentration detected by the conductivity meter is lower than a predetermined value. In S7, when it is determined that the liquid level detected by the liquid level detection means 6 is lower than the specified level and the concentration detected by the conductivity meter is lower than the predetermined level, the amount of the powdered dialysis drug charged is Since it can be determined that there is a shortage, the process proceeds to S8, where the calculation means 9 calculates the shortage amount, and the additional charge amount (number of dissolution bags to be added) corresponding to the shortage amount is displayed on the display means 11. To instruct additional input.

  Then, in S9, the operator waits for an input operation, and when the input operation is performed, it is determined whether or not the input is an instruction to continue the work (S10). If it is determined in S10 that an instruction to continue the operation has been input, the process proceeds to S3, and the additional charging amount of the dialysis powder drug displayed on the display means 11 is input to the dissolution tank 2. If it is determined in S10 that an instruction not to continue the operation has been input, the process proceeds to S11 and the solution in the dissolution tank 2 is discarded.

  If it is determined in S7 that the liquid level detected by the liquid level detecting means 6 is higher than the specified level and the concentration detected by the conductivity meter is higher than a predetermined level, the amount of powdered drug for dialysis input Can be determined to be excessive (the amount of water supply is insufficient), the process proceeds to S12, the calculation means 9 calculates the excess amount, and an erroneous input amount corresponding to the excess amount (dissolved by mistake) The number of bags) is displayed on the display means 11. Then, in S13, the operator waits for an input operation. When the input operation is performed, it is determined whether or not the input is an instruction to continue the work (S14).

  If it is determined in S14 that an instruction to continue the operation has been input, the process proceeds to S15, where the input value is changed to the input amount of dialysis powder drug (number of dissolution bags) suitable for the amount of water supply, and to S2. Will return. If it is determined in S14 that an instruction not to continue the operation has been input, the process proceeds to S16 and the solution in the dissolution tank 2 is discarded. As described above, after the stirring by the stirring means 4, the control for determining the suitability of the amount of the dialysis powder drug introduced into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2 by the determining means 7 is completed. Will be.

  According to the above embodiment, as in the previous embodiment, the liquid level detection means 6 capable of continuously and in real time detecting the liquid level of the water or the solution supplied into the dissolution tank 2, and the liquid level detection means 6. Since it has a judgment means 7 that can judge the suitability of the amount of the dialysis powder drug charged in the dissolution tank 2 with respect to the amount of water supplied in the dissolution tank 2 based on the detected liquid level, Appropriateness of the amount of the powder drug for dialysis charged into the dissolution tank 2 can be accurately determined with a simple configuration.

  In particular, according to the present embodiment, in S7, in addition to determining whether or not the liquid level detected by the liquid level detection means 6 is lower than a specified level, the concentration detected by the conductivity meter is lower than a predetermined level. Therefore, it is possible to determine whether or not the difference in the liquid level is caused by the undissolved residue of the powder drug for dialysis. It can be done. In S7, as in the previous embodiment, only the determination of whether or not the liquid level detected by the liquid level detection means 6 is lower than the standard may be performed.

  As mentioned above, although this embodiment was described, this invention is not limited to this, Based on the liquid level detected by the liquid level detection means 6, the inside of the dissolution tank 2 with respect to the quantity of the water supplied in the dissolution tank 2 As long as it is equipped with a judgment means that can judge the appropriateness of the amount of the dialysis powder drug that is put into the product, it is not limited to the one that calculates the difference between the theoretical value and the actual value of the liquid level, but it can be judged from other parameters. It is good also as what to do. In the present embodiment, the calculation means 9 calculates the excess / deficiency of the powder drug for dialysis charged in the dissolution tank 2 with respect to the amount of water supplied in the dissolution tank 2. It is good also as what judges only the propriety of the input amount of the powder medicine for dialysis.

  In the present embodiment, the auxiliary dissolution tank 3 is provided in addition to the dissolution tank 2, but the liquid level detection similar to that of the dissolution tank 2 is also provided in the auxiliary dissolution tank 3 or the auxiliary dissolution tank 3. Means 6 may be provided, and the liquid level detection means 6 may be electrically connected to the determination means 7. Furthermore, it is assumed that the dialysis powder drug can be dissolved in each of the two dissolution tanks to produce a dialysis stock solution, and the solution is alternately sent from these dissolution tanks to the dialysis treatment device side (dialysis solution supply device, etc.). It may be obtained. In the present embodiment, the same type of dialysis powder drug is added to the dissolution tank 2 and the auxiliary dissolution tank 3 for dissolution, but the dissolution tank 2 and the auxiliary dissolution tank 3 can be dissolved independently. If it is a simple piping configuration, different powder drugs for dialysis (agent A and agent B) may be added and dissolved.

  Further, the judging means 7 determines whether or not the amount of the powder drug for dialysis charged in the dissolving tank is appropriate for the amount of water supplied in the dissolving tank 2 based on the liquid level detected by the liquid level detecting means 6. Although it is determined, based on the liquid level detected by the liquid level detection means 6, it may be determined whether or not the dialysis powder drug remains undissolved in the solution generated in the dissolution tank 2. . In this case, the judging means 7 compares the theoretical value of the liquid level when the powder drug for dialysis is completely dissolved in water with the actual value of the liquid level detected by the liquid level detecting means 6, and the liquid level It is preferable to determine whether or not the powder drug for dialysis remains undissolved from the difference between the theoretical value and the actually measured value. As a result, in addition to causing the liquid level detection means 6 to function as a means for determining the suitability of the amount of the dialysis powder drug added, as a means for determining whether or not the dialysis powder drug remains undissolved. Can function.

Based on the liquid level detected by the liquid level detection means before the stirring by the stirring means in a state where water and the powder drug for dialysis are contained in the dissolution tank, the amount of water supplied to the dissolution tank is Any dissolution apparatus that can determine whether or not the amount of the dialysis powder medicine charged in the dissolution tank can be determined can be applied to a device having a different external shape or one having other functions.

DESCRIPTION OF SYMBOLS 1 Dissolution apparatus 2 Dissolution tank 3 Auxiliary dissolution tank 4 Stirring means 5 Stirring means 6 Liquid level detection means 7 Judgment means 8 Storage means 9 Calculation means 10 Input means 11 Display means L1, L2 Water supply line

Claims (6)

In a dissolution apparatus for dissolving a dialysis powder drug to obtain a dialysis stock solution,
A dissolution tank capable of containing the powder drug for dialysis;
A water supply line for supplying water for dissolving the powder drug for dialysis to the dissolution tank;
A stirring means capable of stirring the solution in the dissolution tank;
Liquid level detection means capable of continuously and in real time detecting the liquid level of water or solution supplied into the dissolution tank;
Based on the liquid level detected by the liquid level detecting means before the stirring by the stirring means in a state where water and the powder drug for dialysis are accommodated in the dissolving tank, they are supplied into the dissolving tank. Judgment means capable of judging the suitability of the amount of the powder drug for dialysis charged into the dissolution tank with respect to the amount of water,
A melting apparatus comprising:   The determination means is detected by the theoretical value of the liquid level when the amount of the powder drug for dialysis charged with respect to the amount of water supplied into the dissolution tank is appropriate, and detected by the liquid level detection means. Compared with the measured value of the liquid level, from the difference between the theoretical value and the measured value of the liquid level, the amount of the powder drug for dialysis charged into the dissolution tank relative to the amount of water supplied into the dissolution tank The dissolution apparatus according to claim 1, wherein suitability can be determined.   The determination means can calculate an excess / deficiency amount of the powder drug for dialysis introduced into the dissolution tank with respect to the amount of water supplied into the dissolution tank from the difference between the theoretical value and the actual measurement value of the liquid level. The melting apparatus according to claim 2.   The powder drug for dialysis is set so that stirring by the stirring means is performed for a predetermined time, and after the predetermined time has elapsed, the powder drug for dialysis charged into the dissolution tank with respect to the amount of water supplied into the dissolution tank by the determination means When it is judged that the quantity of is unsuitable, it will alert | report that, The melt | dissolution apparatus as described in any one of Claims 1-3 characterized by the above-mentioned. An input means for inputting the amount of the dialysis powder drug charged into the dissolution tank is provided, and the determination means includes an input value input by the input means and a liquid detected by the liquid level detection means. The dissolution apparatus according to any one of claims 1 to 4 , wherein an appropriate amount of the powder drug for dialysis can be determined based on the position. Based on the detected liquid level by the liquid level detecting means, according to any one of claims 1 to 5, characterized in that to calculate: volume of dialysis concentrate produced in the dissolving tank Melting device.

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