JP6644857B2 - Melting equipment - Google Patents

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JP6644857B2
JP6644857B2 JP2018212205A JP2018212205A JP6644857B2 JP 6644857 B2 JP6644857 B2 JP 6644857B2 JP 2018212205 A JP2018212205 A JP 2018212205A JP 2018212205 A JP2018212205 A JP 2018212205A JP 6644857 B2 JP6644857 B2 JP 6644857B2
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dialysis
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鈴木 宏章
宏章 鈴木
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Nikkiso Co Ltd
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本発明は、透析用粉末薬剤を溶解して透析用原液を得るための溶解装置に関するものである。   TECHNICAL FIELD The present invention relates to a dissolving apparatus for dissolving a powder drug for dialysis to obtain a stock solution for dialysis.

病院等で腎不全患者の治療に使用される透析液は、一般に重炭酸塩系と酢酸系とに区分され、このうち重炭酸塩系の透析液は、重炭酸ナトリウムを含まないもの(以下、A剤という。)と重炭酸ナトリウム(以下、B剤という。)の2種類の薬剤に水を混合して調整されるものである。近年、運搬性向上の観点から、これらA剤及びB剤を粉末化したもの(以下、「透析用粉末薬剤」という。)を透析治療時間の前に溶解する試みがなされているが、溶解後の溶液(特にB剤)については経時的に濃度の低下が生じやすく、大量の溶液を作り置きしておくことが難しかった。   Dialysis fluids used for treatment of patients with renal failure in hospitals and the like are generally classified into bicarbonate and acetic acid, and bicarbonate-based dialysate does not contain sodium bicarbonate (hereinafter, referred to as It is adjusted by mixing water with two kinds of chemicals, that is, agent A) and sodium bicarbonate (hereinafter, agent B). In recent years, from the viewpoint of improving transportability, attempts have been made to dissolve a powdered version of these agents A and B (hereinafter referred to as “dialysis powder drug”) before the dialysis treatment time. With regard to the solution (particularly, the agent B), the concentration tends to decrease with time, and it was difficult to prepare a large amount of the solution.

このため、透析治療毎に溶解作業が必要となり、従来から溶解のための溶解装置が各種提案されている。例えば特許文献1には、2つの溶解槽を併設した溶解装置が開示されている。かかる構成により、透析終了後、一方の溶解槽に次回の透析に備えて予め透析用粉末薬剤を投入しておき、他方の溶解槽は次回の透析が開始されるまでの間に、洗浄消毒を行うことができる。また、透析中、一方の溶解槽から透析液原液を人工透析液供給装置に供給している間に、他方の溶解槽で透析用粉末薬剤の追加溶解を行うことができる。   Therefore, a dissolving operation is required for each dialysis treatment, and various dissolving apparatuses for dissolving have been conventionally proposed. For example, Patent Literature 1 discloses a melting apparatus provided with two melting tanks. With this configuration, after the dialysis is completed, one of the dissolving tanks is charged with the dialysis powder drug in advance in preparation for the next dialysis, and the other dissolving tank is washed and disinfected before the next dialysis is started. It can be carried out. In addition, during the dialysis, while the dialysate stock solution is being supplied from one dissolving tank to the artificial dialysate supply device, the other dissolving tank can additionally dissolve the dialysis powder drug.

特開2001−9028号公報JP 2001-9028 A

しかしながら、上記従来技術においては、溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の量の適否を判断することが困難であったので、作業者が間違った量の透析用粉末薬剤を投入してしまった場合、不適切な濃度の透析用原液が生成されてしまうという問題があった。また、透析用原液の電導度を測定し、その測定値に基づいて透析用粉末薬剤の投入量の適否を判断することも考えられるが、その場合、攪拌生成後に初めて投入量の適否が判断できることから、投入量が不適切と判断されると、攪拌生成作業をもう一度やり直す必要があった。   However, in the above prior art, it was difficult to judge the appropriateness of the amount of the dialysis powdered drug introduced into the dissolving tank with respect to the amount of water supplied into the dissolving tank. When the amount of the dialysis powder drug is added, there is a problem that an dialysis stock solution having an inappropriate concentration is generated. It is also conceivable to measure the conductivity of the undiluted solution for dialysis and determine the appropriateness of the dosage of the powdered dialysis drug based on the measured value. Therefore, when it is determined that the input amount is inappropriate, it is necessary to perform the stirring and generating operation again.

本発明は、このような事情に鑑みてなされたもので、溶解槽内に投入した透析用粉末薬剤の量の適否を簡易な構成で精度よく判断することができる溶解装置を提供することにある。   The present invention has been made in view of such circumstances, and it is an object of the present invention to provide a dissolving apparatus capable of accurately judging the appropriateness of the amount of a dialysis powder drug put into a dissolving tank with a simple configuration. .

請求項1記載の発明は、透析用粉末薬剤を溶解して透析用原液を得るための溶解装置において、前記透析用粉末薬剤を収容し得る溶解槽と、前記溶解槽に前記透析用粉末薬剤を溶解するための水を供給するための給水ラインと、前記溶解槽内の溶液を攪拌し得る攪拌手段と、前記溶解槽内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能な液位検出手段と、前記液位検出手段により検出された液位に基づいて、前記溶解槽内に供給された水の量に対する前記溶解槽内に投入された透析用粉末薬剤の量の適否を判断し得る判断手段とを備え、前記判断手段は、前記撹拌手段による前記溶液の撹拌を行う前において、前記溶解槽内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、前記液位検出手段により検出された液位の実測値とを比較し、又は前記攪拌手段による前記溶液の攪拌が終了した後において、前記溶解槽内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、前記液位検出手段により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から前記溶解槽内に供給された水の量に対する前記溶解槽内に投入された透析用粉末薬剤の過不足量を算出し得ることを特徴とする。 The invention according to claim 1 is a dissolving apparatus for dissolving a dialysis powder drug to obtain a stock solution for dialysis, wherein a dissolution tank capable of containing the dialysis powder drug, and the dialysis powder drug in the dissolution tank. A water supply line for supplying water for dissolution, a stirring means capable of stirring the solution in the dissolving tank, and a continuous and real-time detection of the level of the water or the solution supplied to the dissolving tank Whether the amount of the dialysis powder drug introduced into the dissolving tank is appropriate for the amount of water supplied to the dissolving tank based on the liquid level detected by the liquid level detecting means and the liquid level detected by the liquid level detecting means. Before the solution is stirred by the stirring means , the determination means of the dialysis powder drug that has been injected with respect to the amount of water supplied into the dissolution tank. The theoretical value of the liquid level when the volume is Compares the measured value of the liquid level detected by the liquid level detecting means, or after the agitation of the solution by the stirring means is completed, is turned relative to the amount of water supplied to the dissolving tank The theoretical value of the liquid level when the amount of the powdered drug for dialysis is appropriate is compared with the measured value of the liquid level detected by the liquid level detecting means, and the theoretical value and the measured value of the liquid level are compared . The difference between the difference and the amount of water supplied to the dissolving tank with respect to the amount of water supplied to the dissolving tank can be calculated.

請求項2記載の発明は、請求項1記載の溶解装置において、前記攪拌手段による攪拌が所定時間行われるよう設定されるとともに、当該所定時間経過後、前記判断手段により前記溶解槽内に供給された水の量に対する前記溶解槽内に投入された透析用粉末薬剤の量が適切でないと判断された場合、その旨を報知することを特徴とする。   According to a second aspect of the present invention, in the dissolving apparatus according to the first aspect, the stirring by the agitating means is set to be performed for a predetermined time, and after the predetermined time has elapsed, the stirring is supplied into the melting tank by the determining means. When it is determined that the amount of the dialysis powdered drug introduced into the dissolution tank with respect to the amount of water that has been discharged is not appropriate, a notification to that effect is provided.

請求項3記載の発明は、請求項1又は請求項2記載の溶解装置において、前記溶解槽内に投入された前記透析用粉末薬剤の量を入力する入力手段を具備するとともに、前記判断手段は、当該入力手段で入力された入力値と前記液位検出手段により検出された液位とに基づいて、透析用粉末薬剤の投入量の適宜を判断し得ることを特徴とする。   According to a third aspect of the present invention, in the dissolving apparatus of the first or second aspect, the dissolving apparatus further includes an input unit for inputting an amount of the powdered dialysis agent charged into the dissolving tank. According to another aspect of the present invention, it is possible to appropriately determine the input amount of the dialysis powder drug based on the input value input by the input means and the liquid level detected by the liquid level detecting means.

請求項4記載の発明は、請求項1〜3の何れか1つに記載の溶解装置において、前記液位検出手段により検出された液位に基づいて、前記溶解槽内で生成された透析用原液の容量を算出し得ることを特徴とする。   According to a fourth aspect of the present invention, there is provided the lysing apparatus according to any one of the first to third aspects, wherein the dialysis is generated in the lysing tank based on the liquid level detected by the liquid level detecting means. It is characterized in that the volume of the stock solution can be calculated.

請求項1の発明によれば、溶解槽内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能な液位検出手段と、液位検出手段により検出された液位に基づいて、溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の量の適否を判断し得る判断手段とを備えたので、溶解槽内に投入した透析用粉末薬剤の量の適否を簡易な構成で精度よく判断することができる。   According to the invention of claim 1, a liquid level detecting means capable of continuously and in real time detecting the liquid level of the water or the solution supplied into the dissolving tank, and a liquid level detected by the liquid level detecting means. The determination means for judging the appropriateness of the amount of the powdered dialysis drug introduced into the dissolving tank with respect to the amount of water supplied into the dissolving tank, Appropriateness of the amount can be accurately determined with a simple configuration.

また、判断手段は、溶解槽内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、液位検出手段により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の量の適否を判断し得るので、投入された透析用粉末薬剤の量の適否をより精度よく判断することができる。   Further, the determining means includes a theoretical value of the liquid level when the amount of the powdered dialysis drug charged with respect to the amount of water supplied into the dissolving tank is appropriate, and a liquid detected by the liquid level detecting means. The measured value of the liquid level is compared with the theoretical value of the liquid level and the difference between the measured value and the measured value is used to judge whether or not the amount of the dialysis powder drug introduced into the dissolving tank with respect to the amount of water supplied into the dissolving tank is appropriate. Therefore, the appropriateness of the amount of the supplied dialysis powder medicine can be more accurately determined.

さらに、判断手段は、液位の理論値と実測値との差から溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の過不足量を算出し得るので、投入された透析用粉末薬剤の量の適否に加え、不足量又は過多量を把握することができ、適正とするために透析用粉末薬剤又は水をどの程度追加すべきか報知させることができる。   Furthermore, since the determination means can calculate the excess or deficiency of the dialysis powder drug introduced into the dissolving tank with respect to the amount of water supplied to the dissolving tank from the difference between the theoretical value and the measured value of the liquid level, In addition to the appropriateness of the amount of the supplied dialysis powder drug, it is possible to grasp the shortage or excess amount, and to be notified of how much dialysis powder drug or water should be added in order to make it appropriate.

請求項2の発明によれば、攪拌手段による攪拌が所定時間行われるよう設定されるとともに、当該所定時間経過後、判断手段により溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の量が適切でないと判断された場合、その旨を報知するので、投入された透析用粉末薬剤の量が適切でない透析用原液を透析治療装置側に送液してしまうのを防止することができる。   According to the second aspect of the present invention, the stirring by the stirring means is set to be performed for a predetermined time, and after the predetermined time has elapsed, the stirring means is supplied to the dissolving tank with respect to the amount of water supplied to the dissolving tank. If it is determined that the amount of the dialysis powder drug is not appropriate, the user is notified that the amount of the dialysis powder drug is not appropriate. Can be prevented.

請求項3の発明によれば、溶解槽内に投入された透析用粉末薬剤の量を入力する入力手段を具備するとともに、判断手段は、当該入力手段で入力された入力値と液位検出手段により検出された液位とに基づいて、透析用粉末薬剤の投入量の適宜を判断し得るので、溶解装置に対して透析用粉末薬剤の投入量を確実に把握させることができ、透析用粉末薬剤の投入量の適否を精度よく判断させることができる。   According to the invention of claim 3, there is provided input means for inputting an amount of the dialysis powdered drug put into the dissolving tank, and the judging means comprises an input value inputted by the input means and a liquid level detecting means. Based on the liquid level detected by the method, it is possible to determine the appropriate amount of the powder medicine for dialysis, it is possible to reliably know the amount of the powder medicine for dialysis to the dissolution apparatus, the powder for dialysis Appropriateness of the dosage of the medicine can be accurately determined.

請求項4の発明によれば、液位検出手段により検出された液位に基づいて、溶解槽内で生成された透析用原液の容量を算出し得るので、液位検出手段について、投入された透析用粉末薬剤の量の適否を判断するための手段として機能させるのに加え、溶解槽内で生成された透析用原液の容量を算出するための手段として機能させることができる。   According to the invention of claim 4, the volume of the undiluted dialysis solution generated in the dissolving tank can be calculated based on the liquid level detected by the liquid level detecting means. In addition to functioning as a means for determining the appropriateness of the amount of the dialysis powder drug, it can function as a means for calculating the volume of the dialysis stock solution generated in the dissolution tank.

本発明の実施形態に係る溶解装置を示す平面図及び正面図Plan view and front view showing a melting apparatus according to an embodiment of the present invention. 同溶解装置の内部構成を示す模式図Schematic diagram showing the internal configuration of the melting device 同溶解装置における制御内容を示すフローチャートFlow chart showing control contents in the melting apparatus 本発明の他の実施形態に係る溶解装置の制御内容を示すフローチャートFlowchart showing control contents of the melting apparatus according to another embodiment of the present invention.

以下、本発明の実施形態について図面を参照しながら具体的に説明する。
本実施形態に係る溶解装置は、透析用粉末薬剤を溶解し透析用原液を得るものであって、図1、2に示すように、透析用粉末薬剤を収容し得る溶解槽2及び補助溶解槽3と、これら溶解槽2及び補助溶解槽3のそれぞれに透析用粉末薬剤を溶解するための水を供給するための給水ラインL1、L2と、溶解槽2及び補助溶解槽3内の液体を攪拌し得る攪拌手段4、5と、液位検出手段6と、記憶手段8及び算出手段9を有した判断手段7と、入力手段10と、表示手段11とから主に構成される。
Hereinafter, embodiments of the present invention will be specifically described with reference to the drawings.
The dissolution apparatus according to the present embodiment is for dissolving a dialysis powder drug to obtain a stock solution for dialysis, and as shown in FIGS. 1 and 2, a dissolution tank 2 and an auxiliary dissolution tank capable of containing the dialysis powder drug. 3, water supply lines L1 and L2 for supplying water for dissolving the dialysis powder drug to each of the dissolving tank 2 and the auxiliary dissolving tank 3, and stirring the liquid in the dissolving tank 2 and the auxiliary dissolving tank 3 It mainly comprises: stirring means 4 and 5 which can be used; liquid level detecting means 6; determining means 7 having storage means 8 and calculating means 9; input means 10; and display means 11.

溶解槽2は、重炭酸ナトリウムを含まないもの(A剤)又は重炭酸ナトリウム(B剤)の2種類のうち何れかから成る透析用粉末薬剤を投入可能な収容空間を有するとともに、給水源Aから延設された給水ラインL1が接続されている。かかる給水ラインL1には、電磁弁等から成るバルブV1が配設されており、このバルブV1を開状態とすることにより溶解槽2内に給水可能とされている。しかして、給水源Aから所定量の水を溶解槽2内に供給して収容させた後、その水の量に対して決められた量(規定量)の透析用粉末薬剤を溶解槽2に投入して攪拌することにより、所定量及び所定濃度の透析用原液を得ることができる。   The dissolving tank 2 has a storage space in which a dialysis powder drug composed of any one of two types, one not containing sodium bicarbonate (agent A) or sodium bicarbonate (agent B), can be charged, and a water source A Is connected to a water supply line L1 extending from the water supply line L1. A valve V1 composed of an electromagnetic valve or the like is provided in the water supply line L1, and water can be supplied into the dissolution tank 2 by opening the valve V1. Thus, after a predetermined amount of water is supplied from the water supply source A into the dissolving tank 2 and accommodated therein, a predetermined amount (prescribed amount) of the dialysis powder drug for the amount of water is supplied to the dissolving tank 2. By adding and stirring, a dialysis stock solution having a predetermined amount and a predetermined concentration can be obtained.

補助溶解槽3は、溶解槽2に投入される透析用粉末薬剤と同種の透析用粉末薬剤を投入可能な空間を有すると共に、溶解槽2の攪拌ラインL3から延設された給水ラインL2が接続されている。かかる給水ラインL2には、電磁弁等からなるバルブV2が配設されており、このバルブV2を開状態にすることにより、溶解槽2より補助溶解槽3内に給水可能とされている。かかる補助溶解槽3は、溶解槽2に比べて相対的に容量が小さなタンクとされ、オーバーフローラインL5にて溶解槽2に接続されている。   The auxiliary dissolving tank 3 has a space in which the same kind of dialysis powder medicine as the dialysis powder medicine to be introduced into the dissolution tank 2 can be introduced, and a water supply line L2 extending from the stirring line L3 of the dissolution tank 2 is connected. Have been. A valve V2 composed of an electromagnetic valve or the like is provided in the water supply line L2. By opening this valve V2, water can be supplied from the dissolution tank 2 into the auxiliary dissolution tank 3. The auxiliary dissolving tank 3 is a tank whose capacity is relatively smaller than that of the dissolving tank 2, and is connected to the dissolving tank 2 via an overflow line L5.

しかして、補助溶解槽3に予め透析用粉末薬剤を投入しておき、治療時、溶解槽2に定められた十分な量の給水を行い、給水ラインL2から給水しつつ攪拌するとともに、攪拌ラインL3に配設されたバルブV3を閉状態にして、オーバーフローラインL5を介して溶解槽2にも溶解液を送液することにより、溶解槽2と補助溶解槽3との両方によって所定量及び所定濃度の透析用原液を生成する。そして、先ず溶解槽2内の透析用原液を透析治療装置側(透析液供給装置等)に送液し、当該溶解槽2が空になると、補助溶解槽3内の透析用原液を継続して送液することができる。なお、補助溶解槽3内の透析用原液を送液している間、溶解槽2に透析用粉末薬剤を投入して溶解させることで、当該溶解槽2単独で透析用原液を生成することができる。   Thus, the powder medicine for dialysis is previously charged into the auxiliary dissolving tank 3, and during treatment, a sufficient amount of water specified in the dissolving tank 2 is supplied, and while the water is supplied from the water supply line L2, stirring is performed. By closing the valve V3 disposed in L3 and sending the dissolving solution also to the dissolving tank 2 via the overflow line L5, a predetermined amount and a predetermined amount are determined by both the dissolving tank 2 and the auxiliary dissolving tank 3. Produce a concentrated stock solution for dialysis. Then, the dialysis stock solution in the dissolution tank 2 is first sent to the dialysis treatment device side (dialysis fluid supply device, etc.), and when the lysis tank 2 becomes empty, the dialysis stock solution in the auxiliary lysis tank 3 is continued. Liquid can be sent. In addition, while feeding the undiluted solution for dialysis in the auxiliary dissolution tank 3, the undiluted solution for dialysis can be generated by the dissolution tank 2 alone by introducing and dissolving the dialysis powder drug into the dissolution tank 2. it can.

よって、補助溶解槽3を具備することにより、治療前(治療前日の夜等)においては、補助溶解槽3に透析用粉末薬剤が投入された状態で溶解槽2に対する洗浄や消毒等を行わせることができるとともに、治療中においては、貯槽として機能させることができる。また、本実施形態に適用される透析用粉末薬剤は、溶解袋に所定量毎に袋詰めされており、作業者が溶解袋を破り、内部の透析用粉末薬剤を溶解槽2又は補助溶解槽3に投入するようになっている。   Therefore, by providing the auxiliary dissolving tank 3, before the treatment (eg, the night before the treatment), the dissolving tank 2 is washed or disinfected while the dialysis powder drug is charged in the auxiliary dissolving tank 3. It can function as a reservoir during treatment. Further, the dialysis powder drug applied to the present embodiment is packed in a dissolving bag at predetermined intervals, and an operator breaks the dissolution bag and dissolves the dialysis powder drug inside the dissolution tank 2 or the auxiliary dissolution tank. 3

攪拌手段4は、溶解槽2内に収容された液体(溶液)を攪拌するためのもので、本実施形態においては、循環ラインL3の先端に接続されたノズルから成る。この循環ラインL3は、溶解槽2の底面から延設され、その先端が当該溶解槽2内に配設された攪拌手段4に接続された循環流路から成るとともに、流路の途中にポンプP1が配設されたものである。しかして、ポンプP1を駆動させると、溶解槽2の液体が攪拌手段4から噴出して循環し得るので、当該溶解槽2内の液体を攪拌することができるのである。   The stirring means 4 is for stirring the liquid (solution) contained in the dissolving tank 2 and, in the present embodiment, comprises a nozzle connected to the tip of the circulation line L3. The circulation line L3 extends from the bottom surface of the dissolving tank 2 and has a distal end formed of a circulating passage connected to the stirring means 4 disposed in the dissolving tank 2, and a pump P1 provided in the middle of the passage. Is arranged. When the pump P1 is driven, the liquid in the dissolving tank 2 can be ejected from the stirring means 4 and circulated, so that the liquid in the dissolving tank 2 can be stirred.

攪拌手段5は、補助溶解槽3内に収容された液体(溶液)を攪拌するためのもので、本実施形態においては、給水ラインL2の先端に接続されたノズルから成る。この給水ラインL2は、溶解槽2の攪拌ラインL3から延設され、その先端が当該補助溶解槽3内に配設された攪拌手段5に接続されている。しかして、溶解槽2に定められた十分な量の給水を行い、その後バルブV2を開きポンプP1を駆動させると、溶解槽2の液体が攪拌手段5から噴出して、当該補助溶解槽3内の透析用粉末薬剤を攪拌するとともに、攪拌ラインL3に配設されたバルブV3を閉状態にして、オーバーフローラインL5を介して溶解槽2にも溶解液を送液し、溶解槽2と補助溶解槽3との両方によって攪拌溶解を行う。   The stirring means 5 is for stirring the liquid (solution) contained in the auxiliary dissolving tank 3, and in the present embodiment, is composed of a nozzle connected to the tip of the water supply line L2. The water supply line L2 extends from the stirring line L3 of the dissolving tank 2 and has a leading end connected to the stirring means 5 provided in the auxiliary dissolving tank 3. When a sufficient amount of water is supplied to the dissolving tank 2 and the valve V2 is opened and the pump P1 is driven thereafter, the liquid in the dissolving tank 2 gushes from the stirring means 5 and the inside of the auxiliary dissolving tank 3 The dialysis powder medicine is stirred and the valve V3 disposed on the stirring line L3 is closed, and the dissolving solution is also sent to the dissolving tank 2 via the overflow line L5, and the dissolving tank 2 and the auxiliary dissolving are dissolved. Stir-dissolution is carried out both with the tank 3.

なお、本実施形態に係る攪拌手段4、5は、循環流路から成る循環ラインL3、給水ラインL2の先端に接続されたノズルから成るものとされているが、溶解槽2及び補助溶解槽3内の溶液を攪拌し得るものであれば、他の形態のもの(例えば、溶解槽2及び補助溶解槽3内で回転駆動可能なインペラ等)としてもよい。また、溶解槽2及び補助溶解槽3の上部に液体をシャワー状に噴出し得るシャワー手段を設け、循環ラインL3、給水ラインL2の先端に当該シャワー手段を接続するようにしてもよい。   In addition, the stirring means 4 and 5 according to the present embodiment are configured to include a circulation line L3 composed of a circulation flow path and a nozzle connected to the tip of the water supply line L2. Other forms (for example, an impeller or the like that can be driven to rotate in the dissolving tank 2 and the auxiliary dissolving tank 3) may be used as long as the solution inside can be stirred. Further, a shower means capable of ejecting a liquid in a shower shape may be provided above the dissolving tank 2 and the auxiliary dissolving tank 3, and the shower means may be connected to the ends of the circulation line L3 and the water supply line L2.

液位検出手段6は、溶解槽2に配設されたセンサから成るもので、溶解槽2内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能なものである。本実施形態に係る液位検出手段6は、溶解槽2の収容空間内において鉛直方向に延設された変位部6aと、溶解槽2内に収容された液体の液面に浮きつつ変位部6aに沿って上下移動可能な浮き手段6bとを有した磁歪式リニア変位センサで構成されており、浮き手段6bの変位部6aに対する位置を連続的且つリアルタイムに検出することにより、液面(すなわち液位)を検知可能とされている。   The liquid level detecting means 6 comprises a sensor arranged in the dissolving tank 2 and can continuously and in real time detect the liquid level of the water or the solution supplied into the dissolving tank 2. The liquid level detecting means 6 according to the present embodiment includes a displacement part 6a extending vertically in the accommodation space of the dissolving tank 2 and a displacement part 6a floating on the liquid surface of the liquid contained in the dissolving tank 2. And a floating means 6b capable of moving up and down along the axis. The position of the floating means 6b with respect to the displacement portion 6a is detected continuously and in real time, and the Position) can be detected.

なお、液位検出手段6は、溶解槽2内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能なものであれば、接触式又は非接触式のどちらのタイプでもよく、本実施形態の如く浮き手段による磁歪式リニア変位センサの他、超音波センサ等により構成するようにしてもよい。また、本実施形態においては、液位検出手段6が溶解槽2のみに配設されているが、当該溶解槽2と共に補助溶解槽3にも配設するようにしてもよい。   The liquid level detecting means 6 may be either a contact type or a non-contact type as long as the liquid level of the water or the solution supplied into the dissolving tank 2 can be detected continuously and in real time. In addition to the magnetostrictive linear displacement sensor using the floating means as in the present embodiment, an ultrasonic sensor or the like may be used. Further, in this embodiment, the liquid level detecting means 6 is provided only in the dissolving tank 2, but may be provided in the auxiliary dissolving tank 3 together with the dissolving tank 2.

また、本実施形態に係る溶解装置1の筐体部には、入力手段10と、表示手段11とが配設されている。入力手段10は、操作者が入力操作可能な操作スイッチやタッチパネル等により構成されたもので、本実施形態においては、溶解槽2又は補助溶解槽3内に投入された透析用粉末薬剤の量を入力し得るものとされている。表示手段11は、液晶モニタ等により構成されたもので、溶解作業に関する種々表示を行い得るものとされている。   In addition, an input unit 10 and a display unit 11 are provided in the housing of the melting apparatus 1 according to the present embodiment. The input means 10 is configured by an operation switch, a touch panel, and the like that can be operated by an operator. In the present embodiment, the input means 10 controls the amount of the dialysis powder drug that has been put into the dissolution tank 2 or the auxiliary dissolution tank 3. It can be entered. The display means 11 is constituted by a liquid crystal monitor or the like, and is capable of performing various displays relating to the melting operation.

ここで、本実施形態に係る溶解装置1は、液位検出手段6、入力手段10及び表示手段11等と電気的に接続された判断手段7を具備している。かかる判断手段7は、例えばマイコン等から成るもので、液位検出手段6により検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断し得るよう構成されている。   Here, the dissolving apparatus 1 according to the present embodiment includes a determination unit 7 electrically connected to the liquid level detection unit 6, the input unit 10, the display unit 11, and the like. The judging means 7 comprises, for example, a microcomputer or the like. Based on the liquid level detected by the liquid level detecting means 6, the dialysis injected into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2 is performed. It is configured to be able to determine the appropriateness of the amount of the powder medicine for use.

本実施形態に係る判断手段7は、溶解槽2内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合(すなわち、所定量の水に対して予め定められた規定量の透析用粉末薬剤が投入された場合)の液位の理論値と、液位検出手段6により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断し得るものとされている。なお、「溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否」を判断することにより、同時に、「溶解槽2内に投入された透析用粉末薬剤の量に対する溶解槽2内に供給された水の量の適否」も判断することができる。   The determination means 7 according to the present embodiment determines that the amount of the dialysis powder medicine that has been input is appropriate for the amount of water supplied into the dissolution tank 2 (that is, a predetermined amount of water is predetermined. The theoretical value of the liquid level when the specified amount of the dialysis powder drug is supplied) is compared with the actual measured value of the liquid level detected by the liquid level detecting means 6, and the theoretical value of the liquid level and the actual measured value are compared. From the difference from the value, it is possible to judge whether the amount of the dialysis powder drug introduced into the dissolving tank 2 is appropriate or not with respect to the amount of water supplied into the dissolving tank 2. It should be noted that by judging “the suitability of the amount of the dialysis powder medicine charged into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2”, at the same time, “dialysis charged into the dissolving tank 2” is determined. The appropriateness of the amount of water supplied into the dissolving tank 2 with respect to the amount of the powdered chemical for use. "

具体的には、判断手段7は、溶解槽2内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合(すなわち、所定量の水に対して予め定められた規定量の透析用粉末薬剤が投入された場合)の液位の理論値を記憶する記憶手段8と、該記憶手段8にて記憶された液位の理論値と液位検出手段6により検出された液位の実測値とを比較(例えば、液位の理論値と液位の実測値との減算や比を算出)する算出手段9とを具備しており、液位の理論値と実測値とが略同一であれば、給水量に対する透析用粉末薬剤の投入量が適正であると判断するようになっている。   Specifically, the judging means 7 determines that the amount of the dialysis powdered drug supplied is appropriate for the amount of water supplied into the dissolving tank 2 (that is, the predetermined amount of water is determined in advance for a predetermined amount of water). Storage means 8 for storing the theoretical value of the liquid level when the prescribed specified amount of the dialysis powder drug is introduced), and the theoretical value of the liquid level and the liquid level detecting means 6 stored in the storage means 8. Calculating means 9 for comparing the detected liquid level with the actually measured value (for example, subtracting the theoretical value of the liquid level from the actually measured value of the liquid level or calculating the ratio); If the measured values are substantially the same, it is determined that the input amount of the powdery drug for dialysis with respect to the water supply amount is appropriate.

一方、本実施形態においては、溶解槽2内に投入された透析用粉末薬剤の量(具体的には、使用した溶解袋の数)を入力手段10にて入力させるとともに、当該入力手段10で入力された入力値と液位検出手段6により検出された液位とに基づいて、透析用粉末薬剤の投入量の適宜を判断し得るものとされている。すなわち、判断手段7は、入力手段10で入力された入力値(溶解袋の数)にて透析用粉末薬剤の投入量(溶解袋の数×1つの溶解袋の容量)を把握し、その入力値と給水量とを比べて「適否」を判断するのである。これにより、溶解装置に対して透析用粉末薬剤の投入量を確実に把握させることができ、透析用粉末薬剤の投入量の適否を精度よく判断させることができる。   On the other hand, in the present embodiment, the amount (specifically, the number of used dissolving bags) of the powdered dialysis agent charged into the dissolving tank 2 is input by the input unit 10, and Based on the input value input and the liquid level detected by the liquid level detecting means 6, it is possible to judge the appropriateness of the input amount of the dialysis powder drug. That is, the judging means 7 grasps the input amount (the number of dissolving bags × the capacity of one dissolving bag) of the powdered drug for dialysis based on the input value (the number of dissolving bags) inputted by the input means 10 and inputs the same. The value is determined by comparing the value with the amount of water supply. Thus, the dispensing device can be reliably made aware of the input amount of the dialysis powder drug, and can appropriately determine whether the input amount of the dialysis powder drug is appropriate.

そして、判断手段7は、液位の実測値が液位の理論値より大きい値の場合、給水量に対する透析用粉末薬剤の投入量が過多である(投入すべき透析用粉末薬剤より多い)と判断するとともに、液位の実測値が液位の理論値より小さい場合、給水量に対する透析用粉末薬剤の投入量が不足である(投入すべき透析用粉末薬剤より少ない)と判断し、給水量に対する透析用粉末薬剤の量が何れも「適正」でないと判断するようになっている。   Then, when the measured value of the liquid level is larger than the theoretical value of the liquid level, the judging means 7 determines that the input amount of the dialysis powder drug to the water supply amount is excessive (greater than the dialysis powder drug to be input). If the actual measured value of the liquid level is smaller than the theoretical value of the liquid level, it is determined that the supply amount of the dialysis powder drug to the water supply amount is insufficient (less than the dialysis powder drug to be supplied), and the water supply amount is determined. It is determined that none of the amounts of the dialysis powder drug is "appropriate".

さらに、本実施形態に係る判断手段7の算出手段9は、液位の理論値と実測値との差から溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の過不足量(不足量又は過多量)を算出し得るよう構成されている。これにより、投入された透析用粉末薬剤の量の適否に加え、不足量又は過多量を把握することができ、適正とするために透析用粉末薬剤又は水をどの程度追加すべきか報知させることができる。   Further, the calculating means 9 of the judging means 7 according to the present embodiment calculates the difference between the theoretical value and the measured value of the liquid level for the amount of water supplied to the dissolving tank 2 with respect to the amount of water supplied to the dissolving tank 2 for dialysis. It is configured to be able to calculate the excess or deficiency (insufficient or excessive) of the powdered medicine. With this, in addition to the appropriateness of the amount of the powdered dialysis powder, the shortage or the excess can be grasped, and the amount of the powdered dialysis drug or water to be made appropriate can be notified. it can.

またさらに、本実施形態に係る判断手段7の算出手段9は、液位検出手段6により検出された液位に基づいて、溶解槽2内で生成された透析用原液の容量を算出し得るよう構成されている。溶解槽2内で生成された透析用原液の容量を算出することにより、例えば透析治療が終了するまで透析用原液が足りるか否かを判断することができる。したがって、液位検出手段6について、投入された透析用粉末薬剤の量の適否を判断するための手段として機能させるのに加え、溶解槽2内で生成された透析用原液の容量を算出するための手段として機能させることができる。   Furthermore, the calculating means 9 of the determining means 7 according to the present embodiment can calculate the volume of the undiluted dialysis solution generated in the dissolving tank 2 based on the liquid level detected by the liquid level detecting means 6. It is configured. By calculating the volume of the undiluted dialysis solution generated in the dissolving tank 2, it is possible to judge whether the undiluted dialysis solution is sufficient, for example, until the dialysis treatment is completed. Therefore, in addition to functioning the liquid level detecting means 6 as a means for judging the appropriateness of the amount of the supplied dialysis powder drug, the liquid level detecting means 6 calculates the volume of the dialysis stock solution generated in the dissolution tank 2. Function.

また、本実施形態に係る溶解装置1は、攪拌手段4による攪拌が所定時間行われるよう設定されるとともに、当該所定時間経過後、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量が適切でないと判断された場合、その旨を報知するようになっている。当該報知は、例えば表示手段11による表示の他、音声によるお知らせ、ブザー等の警告音等であってもよい。   Further, the dissolving apparatus 1 according to the present embodiment is set so that the stirring by the stirring means 4 is performed for a predetermined time, and after the predetermined time has elapsed, the determination means 7 controls the amount of water supplied into the dissolving tank 2. If it is determined that the amount of the powdered dialysis drug introduced into the dissolving tank 2 is not appropriate, the fact is notified. The notification may be, for example, a notification by sound, a warning sound such as a buzzer, or the like, in addition to the display by the display unit 11.

さらに、本実施形態においては、溶解槽2内に水及び透析用粉末薬剤が収容された状態であって攪拌手段4による攪拌前に、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断するよう構成されており、記憶手段8には、水に透析用粉末薬剤が全く溶けていないときの液位(未溶解時の液位)が「液位の理論値」として記憶されている。   Further, in the present embodiment, the amount of water supplied into the dissolving tank 2 by the judging means 7 before the stirring by the stirring means 4 in a state where the water and the dialysis powder drug are contained in the dissolving tank 2. It is configured to judge the appropriateness of the amount of the dialysis powder drug charged into the dissolution tank 2 with respect to the water level in the storage means 8 when the dialysis powder drug is not completely dissolved in water (undissolved). (The liquid level at the time) is stored as “theoretical value of the liquid level”.

次に、本実施形態に係る溶解装置1の制御内容(溶解槽2単独による透析用原液の作製)について、図3のフローチャートに基づいて説明する。
先ず、作業者は、投入する透析用粉末薬剤の量(すなわち、使用する溶解袋の数)を入力手段10にて入力(S1)した後、バルブV1を開状態とすることで溶解槽2内に所定量の水を供給させ(S2)、入力手段10に入力した量(溶解袋)の透析用粉末薬剤を溶解槽2に投入する(S3)。
Next, the contents of control of the dissolving apparatus 1 according to the present embodiment (production of a stock solution for dialysis using the dissolving tank 2 alone) will be described based on the flowchart of FIG.
First, the operator inputs (S1) the amount of the dialysis powder medicine to be charged (that is, the number of dissolving bags to be used) with the input means 10 and then opens the valve V1 to open the dissolving tank 2. Is supplied with a predetermined amount of water (S2), and the amount (dissolution bag) of the dialysis powder medicine input to the input means 10 is put into the dissolution tank 2 (S3).

そして、液位検出手段6にて透析用粉末薬剤の投入直後の液位を検出し(S4)、その検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断手段7にて判断する(S5)。このS5にて透析用粉末薬剤の量が適正であると判断されると、S6に進み、ポンプP1を駆動して攪拌手段4を作動させ、溶解槽2内の水及び透析用粉末薬剤を攪拌して溶解させることにより所定濃度の透析用原液を作製する。   Then, the liquid level detection means 6 detects the liquid level immediately after the introduction of the dialysis powder drug (S4), and based on the detected liquid level, the dissolution tank with respect to the amount of water supplied into the dissolution tank 2. The determination means 7 determines whether the amount of the powdered dialysis drug introduced into the sample 2 is appropriate (S5). If it is determined in step S5 that the amount of the dialysis powder drug is appropriate, the process proceeds to S6, in which the pump P1 is driven to activate the stirring means 4, and the water in the dissolution tank 2 and the dialysis powder drug are stirred. To prepare a stock solution for dialysis at a predetermined concentration.

一方、S5にて透析用粉末薬剤の量が適正でないと判断されると、S7に進み、液位検出手段6にて検出された液位が規定より低いか否かが判断され、低いと判断されると、透析用粉末薬剤の投入量が不足していると判断できるので、S8に進み、算出手段9にて当該不足量を算出するとともに、その不足量に応じた追加投入量(追加する溶解袋の数)を表示手段11にて表示することで追加投入を指示する。   On the other hand, if it is determined in S5 that the amount of the dialysis powder drug is not appropriate, the process proceeds to S7, where it is determined whether or not the liquid level detected by the liquid level detecting means 6 is lower than a specified value. Then, since it can be determined that the input amount of the powder medicine for dialysis is insufficient, the process proceeds to S8, and the calculating unit 9 calculates the insufficient amount, and further adds (adds) the amount according to the insufficient amount. The number of dissolving bags) is displayed on the display means 11 to instruct additional feeding.

そして、S9にて作業者による入力操作を待ち、入力操作が行われると、その入力が作業を継続する旨の指示であるか否かが判断される(S10)。S10にて作業を継続する旨の指示が入力されたと判断されると、S3に進み、表示手段11で表示された追加投入量の透析用粉末薬剤を溶解槽2に投入させる。なお、S10にて作業を継続しない旨の指示が入力されたと判断されると、S11に進み、溶解槽2内の溶液を廃棄させる。   In S9, an input operation by the operator is waited. When the input operation is performed, it is determined whether or not the input is an instruction to continue the operation (S10). If it is determined in S10 that an instruction to continue the work has been input, the process proceeds to S3, and the additional amount of the dialysis powder medicine displayed on the display means 11 is injected into the dissolution tank 2. If it is determined in S10 that an instruction not to continue the work has been input, the process proceeds to S11, and the solution in the dissolution tank 2 is discarded.

また、S7にて液位検出手段6にて検出された液位が規定より高いと判断されると、透析用粉末薬剤の投入量が過多である(給水量が不足している)と判断できるので、S12に進み、算出手段9にて当該過多量を算出するとともに、その過多量に応じた誤投入量(誤って使用した溶解袋の数)を表示手段11にて表示する。そして、S13にて作業者による入力操作を待ち、入力操作が行われると、その入力が作業を継続する旨の指示であるか否かが判断される(S14)。   When it is determined in S7 that the liquid level detected by the liquid level detecting means 6 is higher than the specified value, it can be determined that the amount of the powdered dialysis agent used is excessive (the amount of supplied water is insufficient). Therefore, the process proceeds to S12, and the calculating means 9 calculates the excess amount, and displays the erroneous input amount (the number of erroneously used dissolving bags) corresponding to the excess amount on the display means 11. Then, in S13, an input operation by the operator is waited, and when the input operation is performed, it is determined whether or not the input is an instruction to continue the operation (S14).

S14にて業を継続する旨の指示が入力されたと判断されると、S15に進み、給水量に適合する透析用粉末薬剤の投入量(溶解袋の数)に入力値が変更され、S2に戻ることとなる。なお、S14にて作業を継続しない旨の指示が入力されたと判断されると、S16に進み、溶解槽2内の溶液を廃棄させる。以上で、攪拌手段4による攪拌前に、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断するための制御が終了することとなる。   If it is determined in S14 that an instruction to continue the operation has been input, the process proceeds to S15, in which the input value is changed to the input amount (the number of dissolving bags) of the dialysis powder drug suitable for the water supply amount, and the process proceeds to S2. I will return. If it is determined in S14 that an instruction not to continue the work has been input, the process proceeds to S16, and the solution in the dissolution tank 2 is discarded. As described above, before the stirring by the stirring means 4, the control for judging by the judging means 7 whether or not the amount of the dialysis powder drug put into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2 is appropriate. It will end.

上記実施形態によれば、溶解槽2内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能な液位検出手段6と、液位検出手段6により検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断し得る判断手段7とを備えたので、溶解槽2内に投入した透析用粉末薬剤の量の適否を簡易な構成で精度よく判断することができる。   According to the above embodiment, the liquid level detecting means 6 capable of detecting the liquid level of the water or the solution supplied into the dissolving tank 2 continuously and in real time, and the liquid level detected by the liquid level detecting means 6 A determination means 7 for determining whether or not the amount of the dialysis powdered drug introduced into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2 is provided. Appropriateness of the amount of the dialysis powder drug can be accurately determined with a simple configuration.

特に、本実施形態に係る判断手段7は、溶解槽2内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、液位検出手段により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断し得るので、投入された透析用粉末薬剤の量の適否をより精度よく判断することができる。   In particular, the judging means 7 according to the present embodiment determines the theoretical value of the liquid level when the amount of the powdered dialysis medicine supplied is appropriate for the amount of water supplied into the dissolving tank 2, and the liquid level. The measured level of the liquid detected by the detecting means is compared with the measured value, and the difference between the theoretical value and the measured value of the level is compared with the amount of water supplied to the dissolving tank 2 for the dialysis injected into the dissolving tank 2. The appropriateness of the amount of the powder medicine for dialysis can be determined, so that the appropriateness of the amount of the supplied dialysis powder medicine can be determined with higher accuracy.

さらに、本実施形態においては、攪拌手段4による攪拌が所定時間行われるよう設定されるとともに、当該所定時間経過後、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量が適切でないと判断された場合、その旨を報知するので、投入された透析用粉末薬剤の量が適切でない透析用原液を透析治療装置側(透析液供給装置等)に送液してしまうのを防止することができる。なお、攪拌のための所定時間は、予め記憶されていてもよく、或いは入力手段10にて入力するものであってもよい。   Furthermore, in the present embodiment, the stirring by the stirring means 4 is set to be performed for a predetermined time, and after the predetermined time has elapsed, the determination means 7 controls the amount of water supplied to the dissolution tank 2 with respect to the amount of water supplied into the dissolution tank 2. If it is determined that the amount of the dialysis powder drug input to the dialysis treatment device is not appropriate, the user is notified that the amount of the dialysis powder drug input is not appropriate. To the apparatus) can be prevented. The predetermined time for stirring may be stored in advance, or may be input by the input unit 10.

またさらに、本実施形態においては、溶解槽2内に水及び透析用粉末薬剤が収容された状態であって攪拌手段4による攪拌前に、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断するので、透析用原液の生成作業前に確実に透析用粉末薬剤の投入量の適否を判断することができ、投入量が適正でないと判断された場合であっても攪拌作業を繰り返し行わせる必要がないことから作業性を向上させることができる。   Further, in the present embodiment, the water supplied to the dissolving tank 2 by the judging means 7 before the stirring by the stirring means 4 is a state in which the water and the dialysis powder drug are contained in the dissolving tank 2. Since the suitability of the amount of the powdered dialysis drug in the dissolution tank 2 with respect to the amount is determined, it is possible to reliably determine the appropriateness of the input amount of the powdered dialysis drug before the work of generating the undiluted dialysis solution. Even when it is determined that the amount is not appropriate, the workability can be improved because it is not necessary to repeatedly perform the stirring operation.

次に、本発明の他の実施形態に係る溶解装置1の制御内容について、図4のフローチャートに基づいて説明する。ここで、本実施形態においては、攪拌手段4による攪拌後に、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断するよう構成されており、記憶手段8には、水に透析用粉末薬剤が完全に溶けときの液位(溶解時の液位)が「液位の理論値」として記憶されている。 Next, the control contents of the melting apparatus 1 according to another embodiment of the present invention will be described based on the flowchart of FIG. Here, in the present embodiment, after the stirring by the stirring means 4, the judging means 7 judges whether the amount of the dialysis powder drug put into the dissolving tank 2 is appropriate for the amount of water supplied into the dissolving tank 2. being configured to, in the storage means 8, dialysis water powder medicament liquid level when fully melted (dissolution time of the liquid level) is stored as "theoretical value of the liquid level."

先ず、作業者は、投入する透析用粉末薬剤の量(すなわち、使用する溶解袋の数)を入力手段10にて入力(S1)した後、バルブV1を開状態とすることで溶解槽2内に所定量の水を供給させ(S2)、入力手段10に入力した量(溶解袋)の透析用粉末薬剤を溶解槽2に投入する(S3)。そして、S4にてポンプP1を駆動して攪拌手段4を作動させ、溶解槽2内の水及び透析用粉末薬剤を所定時間攪拌して溶解させることにより溶液(透析用原液)を作製する。   First, the operator inputs (S1) the amount of the dialysis powder medicine to be charged (that is, the number of dissolving bags to be used) with the input means 10 and then opens the valve V1 to open the dissolving tank 2. Is supplied with a predetermined amount of water (S2), and the amount (dissolution bag) of the dialysis powder medicine input to the input means 10 is put into the dissolution tank 2 (S3). Then, in step S4, the pump P1 is driven to operate the stirring means 4, and the water and the dialysis powder drug in the dissolution tank 2 are stirred and dissolved for a predetermined time to prepare a solution (undiluted solution for dialysis).

その後、液位検出手段6にて水及び透析用粉末薬剤の攪拌終了後の液位を検出し(S5)、その検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断手段7にて判断する(S6)。このS6にて透析用粉末薬剤の量が適正であると判断されると、一連の攪拌及び溶解作業が終了することとなる。   Then, the liquid level after the completion of the stirring of the water and the dialysis powder drug is detected by the liquid level detecting means 6 (S5), and based on the detected liquid level, the amount of water supplied into the dissolving tank 2 is determined. The determination means 7 determines whether or not the amount of the dialysis powdered drug that has been introduced into the dissolving tank 2 is appropriate (S6). If it is determined in step S6 that the amount of the dialysis powder drug is appropriate, a series of stirring and dissolving operations is completed.

一方、S6にて透析用粉末薬剤の量が適正でないと判断されると、S7に進み、液位検出手段6にて検出された液位が規定より低いか否かが判断されるとともに、図示しない電導度計にて検出された濃度が所定より低いか否かが判断される。S7にて、液位検出手段6にて検出された液位が規定より低く、且つ、電導度計にて検出された濃度が所定より低いと判断されると、透析用粉末薬剤の投入量が不足していると判断できるので、S8に進み、算出手段9にて当該不足量を算出するとともに、その不足量に応じた追加投入量(追加する溶解袋の数)を表示手段11にて表示することで追加投入を指示する。   On the other hand, if it is determined in S6 that the amount of the dialysis powder drug is not appropriate, the process proceeds to S7, where it is determined whether or not the liquid level detected by the liquid level detecting means 6 is lower than a specified value. It is determined whether or not the concentration detected by the conductivity meter is lower than a predetermined value. In S7, when it is determined that the liquid level detected by the liquid level detecting means 6 is lower than the specified value and the concentration detected by the conductivity meter is lower than a predetermined value, the input amount of the powder medicine for dialysis is reduced. Since it can be determined that there is a shortage, the process proceeds to S8, and the calculating unit 9 calculates the shortage amount, and displays the additional input amount (the number of dissolving bags to be added) according to the shortage on the display unit 11. Instruct additional input.

そして、S9にて作業者による入力操作を待ち、入力操作が行われると、その入力が作業を継続する旨の指示であるか否かが判断される(S10)。S10にて作業を継続する旨の指示が入力されたと判断されると、S3に進み、表示手段11で表示された追加投入量の透析用粉末薬剤を溶解槽2に投入させる。なお、S10にて作業を継続しない旨の指示が入力されたと判断されると、S11に進み、溶解槽2内の溶液を廃棄させる。   In S9, an input operation by the operator is waited. When the input operation is performed, it is determined whether or not the input is an instruction to continue the operation (S10). If it is determined in S10 that an instruction to continue the work has been input, the process proceeds to S3, and the additional amount of the dialysis powder medicine displayed on the display means 11 is injected into the dissolution tank 2. If it is determined in S10 that an instruction not to continue the work is input, the process proceeds to S11, and the solution in the dissolution tank 2 is discarded.

また、S7にて液位検出手段6にて検出された液位が規定より高く、且つ、電導度計にて検出された濃度が所定より高いと判断されると、透析用粉末薬剤の投入量が過多である(給水量が不足している)と判断できるので、S12に進み、算出手段9にて当該過多量を算出するとともに、その過多量に応じた誤投入量(誤って使用した溶解袋の数)を表示手段11にて表示する。そして、S13にて作業者による入力操作を待ち、入力操作が行われると、その入力が作業を継続する旨の指示であるか否かが判断される(S14)。   If it is determined in S7 that the liquid level detected by the liquid level detecting means 6 is higher than the specified value and the concentration detected by the electric conductivity meter is higher than a predetermined value, the amount of the dialysis powder drug to be injected is determined. Can be determined to be excessive (the amount of supplied water is insufficient), the process proceeds to S12, and the calculating means 9 calculates the excessive amount, and the erroneous input amount (the erroneously used melting The number of bags is displayed on the display means 11. Then, in S13, an input operation by the operator is waited, and when the input operation is performed, it is determined whether or not the input is an instruction to continue the operation (S14).

S14にて業を継続する旨の指示が入力されたと判断されると、S15に進み、給水量に適合する透析用粉末薬剤の投入量(溶解袋の数)に入力値が変更され、S2に戻ることとなる。なお、S14にて作業を継続しない旨の指示が入力されたと判断されると、S16に進み、溶解槽2内の溶液を廃棄させる。以上で、攪拌手段4による攪拌後に、判断手段7により溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断するための制御が終了することとなる。   If it is determined in S14 that an instruction to continue the operation has been input, the process proceeds to S15, in which the input value is changed to the input amount (the number of dissolving bags) of the dialysis powder drug suitable for the water supply amount, and the process proceeds to S2. I will return. If it is determined in S14 that an instruction not to continue the work is input, the process proceeds to S16, and the solution in the dissolution tank 2 is discarded. As described above, after the stirring by the stirring means 4, the control for judging the appropriateness of the amount of the dialysis powder drug put into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2 by the judging means 7 ends. Will be done.

上記実施形態によれば、先の実施形態と同様、溶解槽2内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能な液位検出手段6と、液位検出手段6により検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断し得る判断手段7とを備えたので、溶解槽2内に投入した透析用粉末薬剤の量の適否を簡易な構成で精度よく判断することができる。   According to the above embodiment, as in the previous embodiment, the liquid level detecting means 6 capable of continuously and real time detecting the liquid level of the water or the solution supplied into the dissolving tank 2 and the liquid level detecting means 6 And determining means 7 for determining, based on the detected liquid level, whether the amount of the dialysis powdered drug introduced into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2 is appropriate. Appropriateness of the amount of the dialysis powder drug put into the dissolution tank 2 can be accurately determined with a simple configuration.

特に、本実施形態によれば、S7にて、液位検出手段6にて検出された液位が規定より低いか否かの判断に加え、電導度計にて検出された濃度が所定より低いか否かの判断がなされているので、当該液位の相違が透析用粉末薬剤の溶け残りに起因しているのか否かをも判別することができ、より精度が高い判断手段7による判断を行わせることができるのである。なお、S7において、先の実施形態と同様、液位検出手段6にて検出された液位が規定より低いか否かの判断のみ行わせるものとしてもよい。   In particular, according to the present embodiment, in S7, in addition to determining whether the liquid level detected by the liquid level detecting means 6 is lower than a specified value, the concentration detected by the conductivity meter is lower than a predetermined value. Since it has been determined whether or not the difference in the liquid level is caused by the undissolved portion of the dialysis powder drug, it is possible to determine whether or not the difference in the liquid level is due to the undissolved portion of the dialysis powder drug. It can be done. In S7, as in the previous embodiment, only the determination as to whether or not the liquid level detected by the liquid level detecting means 6 is lower than a specified value may be made.

以上、本実施形態について説明したが、本発明はこれに限定されず、液位検出手段6により検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の量の適否を判断し得る判断手段を具備したものであれば、液位の理論値と実測値との差を算出するものに限らず、他のパラメータから判断するものとしてもよい。また、本実施形態においては、溶解槽2内に供給された水の量に対する溶解槽2内に投入された透析用粉末薬剤の過不足量を算出手段9にて算出しているが、当該算出を行わず、透析用粉末薬剤の投入量の適否のみを判断するものとしてもよい。   The present embodiment has been described above, but the present invention is not limited to this. Based on the liquid level detected by the liquid level detecting means 6, the amount of water supplied to the As long as it is provided with a judging means capable of judging the appropriateness of the amount of the dialysis powder drug put into the apparatus, the judgment is not limited to calculating the difference between the theoretical value and the actually measured value of the liquid level, and from other parameters. You may do it. In this embodiment, the calculating means 9 calculates the excess or deficiency of the powdered dialysis agent charged into the dissolving tank 2 with respect to the amount of water supplied into the dissolving tank 2. May not be performed, and only the appropriateness of the input amount of the dialysis powder drug may be determined.

なお、本実施形態においては、溶解槽2に加えて補助溶解槽3を具備しているが、溶解槽2のみを具備したもの、或いは補助溶解槽3にも溶解槽2と同様の液位検出手段6を具備させ、その液位検出手段6を判断手段7に電気的に接続したもの等としてもよい。さらに、2つの溶解槽のそれぞれで透析用粉末薬剤を溶解して透析用原液を生成し得るものとし、それら溶解槽から透析治療装置側(透析液供給装置等)に対して交互に送液し得るものとしてもよい。また、本実施形態においては、溶解槽2及び補助溶解槽3に同種の透析用粉末薬剤を投入して溶解するものとしているが、溶解槽2と補助溶解槽3がそれぞれ独立して溶解が可能な配管構成であれば、互いに異なる透析用粉末薬剤(A剤とB剤)をそれぞれ投入して溶解可能なものとしてもよい。   In the present embodiment, the auxiliary dissolving tank 3 is provided in addition to the dissolving tank 2, but the liquid dissolving tank 2 alone or the auxiliary dissolving tank 3 has the same liquid level detection as the dissolving tank 2. Means 6 may be provided, and the liquid level detecting means 6 may be electrically connected to the judging means 7. Further, it is assumed that the dialysis powder drug can be dissolved in each of the two dissolution tanks to produce a stock solution for dialysis, and the solution is alternately sent from these dissolution tanks to the dialysis treatment device side (dialysis solution supply device, etc.). It may be obtained. Further, in the present embodiment, the same type of dialysis powder drug is supplied and dissolved in the dissolving tank 2 and the auxiliary dissolving tank 3, but the dissolving tank 2 and the auxiliary dissolving tank 3 can be independently dissolved. With a proper piping configuration, different dialysis powder drugs (agent A and agent B) may be charged and dissolved, respectively.

さらに、判断手段7は、液位検出手段6により検出された液位に基づいて、溶解槽2内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の量の適否を判断しているが、液位検出手段6により検出された液位に基づいて、溶解槽2内で生成された溶液における透析用粉末薬剤の溶け残りの有無の判断も併せて行うものとしてもよい。この場合、判断手段7は、透析用粉末薬剤が水に完全に溶解したときの液位の理論値と、液位検出手段6により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から透析用粉末薬剤の溶け残りの有無を判断するのが好ましい。これにより、液位検出手段6について、投入された透析用粉末薬剤の量の適否を判断するための手段として機能させるのに加え、透析用粉末薬剤の溶け残りの有無を判断するための手段として機能させることができる。   Further, the judging means 7 judges whether or not the amount of the dialysis powder drug charged into the dissolving tank with respect to the amount of water supplied into the dissolving tank 2 based on the liquid level detected by the liquid level detecting means 6. Although the determination is made, the determination of the presence or absence of the undissolved powder medicine for dialysis in the solution generated in the dissolving tank 2 may be performed based on the liquid level detected by the liquid level detecting means 6. . In this case, the judging means 7 compares the theoretical value of the liquid level when the powdered dialysis drug is completely dissolved in water with the actually measured value of the liquid level detected by the liquid level detecting means 6, and It is preferable to determine the presence or absence of undissolved powder medicine for dialysis from the difference between the theoretical value and the measured value. Thus, the liquid level detecting means 6 functions as a means for judging the appropriateness of the amount of the supplied dialysis powder medicine, and as a means for judging whether or not the dialysis powder medicine remains undissolved. Can work.

液位検出手段により検出された液位に基づいて、溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の量の適否を判断し得るとともに、溶解槽内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、液位検出手段により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から溶解槽内に供給された水の量に対する溶解槽内に投入された透析用粉末薬剤の過不足量を算出し得る溶解装置であれば、外観形状が異なるもの或いは他の機能が付加されたもの等にも適用することができる。   Based on the liquid level detected by the liquid level detecting means, it is possible to judge the suitability of the amount of the dialysis powder drug put into the dissolution tank with respect to the amount of water supplied into the dissolution tank, The theoretical value of the liquid level when the amount of the supplied dialysis powder drug is appropriate with respect to the supplied water amount is compared with the actually measured value of the liquid level detected by the liquid level detecting means. If it is a dissolving device that can calculate the excess or deficiency of the powdered dialysis drug introduced into the dissolving tank with respect to the amount of water supplied into the dissolving tank from the difference between the theoretical value and the measured value of the liquid level, However, the present invention can be applied to a device having a different function or a device having another function.

1 溶解装置
2 溶解槽
3 補助溶解槽
4 攪拌手段
5 攪拌手段
6 液位検出手段
7 判断手段
8 記憶手段
9 算出手段
10 入力手段
11 表示手段
L1、L2 給水ライン
DESCRIPTION OF SYMBOLS 1 Dissolution apparatus 2 Dissolution tank 3 Auxiliary dissolution tank 4 Stirring means 5 Stirring means 6 Liquid level detection means 7 Judgment means 8 Storage means 9 Calculation means 10 Input means 11 Display means L1, L2 Water supply line

Claims (4)

透析用粉末薬剤を溶解して透析用原液を得るための溶解装置において、
前記透析用粉末薬剤を収容し得る溶解槽と、
前記溶解槽に前記透析用粉末薬剤を溶解するための水を供給するための給水ラインと、
前記溶解槽内の溶液を攪拌し得る攪拌手段と、
前記溶解槽内に供給された水又は溶液の液位を連続的且つリアルタイムに検出可能な液位検出手段と、
前記液位検出手段により検出された液位に基づいて、前記溶解槽内に供給された水の量に対する前記溶解槽内に投入された透析用粉末薬剤の量の適否を判断し得る判断手段と、
を備え、前記判断手段は、前記撹拌手段による前記溶液の撹拌を行う前において、前記溶解槽内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、前記液位検出手段により検出された液位の実測値とを比較し、又は前記攪拌手段による前記溶液の攪拌が終了した後において、前記溶解槽内に供給された水の量に対して投入された透析用粉末薬剤の量が適正である場合の液位の理論値と、前記液位検出手段により検出された液位の実測値とを比較し、当該液位の理論値と実測値との差から前記溶解槽内に供給された水の量に対する前記溶解槽内に投入された透析用粉末薬剤の過不足量を算出し得ることを特徴とする溶解装置。
In a dissolving apparatus for dissolving a dialysis powder drug to obtain a dialysis stock solution,
A dissolution tank capable of containing the dialysis powder drug,
A water supply line for supplying water for dissolving the dialysis powder drug to the dissolution tank,
Stirring means capable of stirring the solution in the dissolving tank,
Liquid level detection means capable of continuously and in real time detecting the liquid level of the water or solution supplied into the dissolving tank,
Based on the liquid level detected by the liquid level detecting means, a determining means capable of determining whether the amount of the dialysis powder drug put into the dissolving tank with respect to the amount of water supplied into the dissolving tank is appropriate. ,
The determination means, before performing the stirring of the solution by the stirring means , the amount of the dialysis powder drug that is input to the amount of water supplied into the dissolution tank is appropriate Compare the theoretical value of the liquid level with the actually measured value of the liquid level detected by the liquid level detecting means, or after the stirring of the solution by the stirring means is completed, the water supplied into the dissolving tank. The theoretical value of the liquid level when the amount of the dialysis powdered drug that has been input with respect to the amount of the liquid is appropriate, and the actual measured value of the liquid level detected by the liquid level detecting means are compared . A dissolving apparatus characterized in that it is possible to calculate an excess or deficiency of a powdered dialysis agent introduced into the dissolving tank with respect to an amount of water supplied into the dissolving tank from a difference between a theoretical value and an actually measured value.
前記攪拌手段による攪拌が所定時間行われるよう設定されるとともに、当該所定時間経過後、前記判断手段により前記溶解槽内に供給された水の量に対する前記溶解槽内に投入された透析用粉末薬剤の量が適切でないと判断された場合、その旨を報知することを特徴とする請求項1記載の溶解装置。   The stirring by the stirring means is set to be performed for a predetermined time, and after the lapse of the predetermined time, the dialysis powder drug put into the dissolution tank with respect to the amount of water supplied to the dissolution tank by the determination means. 2. The dissolving apparatus according to claim 1, wherein when it is determined that the amount is not appropriate, the fact is notified. 前記溶解槽内に投入された前記透析用粉末薬剤の量を入力する入力手段を具備するとともに、前記判断手段は、当該入力手段で入力された入力値と前記液位検出手段により検出された液位とに基づいて、透析用粉末薬剤の投入量の適宜を判断し得ることを特徴とする請求項1又は請求項2記載の溶解装置。   Input means for inputting the amount of the dialysis powder drug put into the dissolving tank is provided, and the determination means includes an input value input by the input means and a liquid detected by the liquid level detection means. 3. The dissolving apparatus according to claim 1, wherein an appropriate amount of the injection amount of the dialysis powder drug can be determined based on the position. 前記液位検出手段により検出された液位に基づいて、前記溶解槽内で生成された透析用原液の容量を算出し得ることを特徴とする請求項1〜3の何れか1つに記載の溶解装置。   The volume of the undiluted dialysis solution generated in the dissolution tank can be calculated based on the liquid level detected by the liquid level detection unit, according to any one of claims 1 to 3, wherein Melting equipment.
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