JP6416772B2 - ３ｄプリンティングによる小滴集合 - Google Patents

３ｄプリンティングによる小滴集合 Download PDF

Info

Publication number
JP6416772B2
JP6416772B2 JP2015546096A JP2015546096A JP6416772B2 JP 6416772 B2 JP6416772 B2 JP 6416772B2 JP 2015546096 A JP2015546096 A JP 2015546096A JP 2015546096 A JP2015546096 A JP 2015546096A JP 6416772 B2 JP6416772 B2 JP 6416772B2
Authority
JP
Japan
Prior art keywords
droplet
droplets
medium
aqueous medium
hydrophobic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015546096A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016508076A (ja
JP2016508076A5 (enExample
Inventor
ヘーガン プライス ベイリー、ジョン
ヘーガン プライス ベイリー、ジョン
ヴィラー、ガブリエル
ディー グラハム、アレクサンダー
ディー グラハム、アレクサンダー
Original Assignee
オックスフォード ユニヴァーシティ イノヴェーション リミテッド
オックスフォード ユニヴァーシティ イノヴェーション リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オックスフォード ユニヴァーシティ イノヴェーション リミテッド, オックスフォード ユニヴァーシティ イノヴェーション リミテッド filed Critical オックスフォード ユニヴァーシティ イノヴェーション リミテッド
Publication of JP2016508076A publication Critical patent/JP2016508076A/ja
Publication of JP2016508076A5 publication Critical patent/JP2016508076A5/ja
Application granted granted Critical
Publication of JP6416772B2 publication Critical patent/JP6416772B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/112—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30—Auxiliary operations or equipment
    • B29C64/386—Data acquisition or data processing for additive manufacturing
    • B29C64/393—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C69/00—Combinations of shaping techniques not provided for in a single one of main groups B29C39/00 - B29C67/00, e.g. associations of moulding and joining techniques; Apparatus therefore
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C09B57/001—Pyrene dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015546096A 2012-12-07 2013-12-06 ３ｄプリンティングによる小滴集合 Active JP6416772B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1222052.1 2012-12-07
GB201222052 2012-12-07
PCT/GB2013/053229 WO2014087175A2 (en) 2012-12-07 2013-12-06 Droplet assembly by 3d printing

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018188547A Division JP6782746B2 (ja) 2012-12-07 2018-10-03 ３ｄプリンティングによる小滴集合

Publications (3)

Publication Number Publication Date
JP2016508076A JP2016508076A (ja) 2016-03-17
JP2016508076A5 JP2016508076A5 (enExample) 2017-02-02
JP6416772B2 true JP6416772B2 (ja) 2018-10-31

Family

ID=49765557

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015546096A Active JP6416772B2 (ja) 2012-12-07 2013-12-06 ３ｄプリンティングによる小滴集合
JP2018188547A Active JP6782746B2 (ja) 2012-12-07 2018-10-03 ３ｄプリンティングによる小滴集合

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018188547A Active JP6782746B2 (ja) 2012-12-07 2018-10-03 ３ｄプリンティングによる小滴集合

Country Status (6)

Country Link
US (2) US11213797B2 (enExample)
EP (1) EP2928610A2 (enExample)
JP (2) JP6416772B2 (enExample)
KR (2) KR102284661B1 (enExample)
CN (1) CN105188934B (enExample)
WO (1) WO2014087175A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
KR102284661B1 (ko) 2012-12-07 2021-08-02 옥스포드 유니버시티 이노베이션 리미티드 3d 프린팅에 의한 비말 어셈블리
US9854828B2 (en) 2014-09-29 2018-01-02 William Langeland Method, system and apparatus for creating 3D-printed edible objects
CN106273438B (zh) * 2015-05-11 2019-11-05 三纬国际立体列印科技股份有限公司 立体打印成型结构
DE102015212193A1 (de) * 2015-06-30 2017-01-05 Robert Bosch Gmbh 3D-Druck mit verbesserter Formwiedergabe und Festigkeit
GB2546340A (en) * 2016-01-18 2017-07-19 Isis Innovation Improving security protocols
US20190093071A1 (en) 2016-03-01 2019-03-28 Oxford University Innovation Limited 3D Printing Of A Cellularised Scaffold
GB201603591D0 (en) * 2016-03-01 2016-04-13 Isis Innovation Improved promotors and compositions
CN107457983B (zh) * 2016-05-31 2019-11-29 珠海赛纳打印科技股份有限公司 一种3d物体喷墨打印方法及系统
US10654040B2 (en) * 2016-08-18 2020-05-19 Northeastern University Platform for liquid droplet formation and isolation
EP3362260B1 (de) * 2016-10-17 2019-06-19 Wacker Chemie AG Verfahren zur herstellung von siliconelastomerteilen mit erhöhter druckqualität
US11407221B2 (en) 2016-10-25 2022-08-09 Hewlett-Packard Development Company, L.P. Maintaining a print quality parameter in a printer
TWI631985B (zh) * 2016-10-26 2018-08-11 財團法人金屬工業研究發展中心 微粒製造方法
KR101957415B1 (ko) * 2017-06-23 2019-03-12 주식회사 팡세 3d 프린팅용 조성물 및 이를 이용한 3d 프린팅 방법
US11434454B2 (en) 2017-12-22 2022-09-06 Church & Dwight Co., Inc. Laundry detergent composition
CN109581185B (zh) * 2018-11-16 2021-11-09 北京时代民芯科技有限公司 SoC芯片激光模拟单粒子辐照检测及故障定位方法及系统
CN116440969A (zh) * 2018-11-27 2023-07-18 斯蒂拉科技公司 具有优化的相流的微流控芯片架构
EP3898193B1 (en) 2018-12-19 2023-07-26 Jabil Inc. 3d printing liquefier nozzle flexure for improved ironing
CN109885894B (zh) * 2019-01-24 2023-05-05 江西理工大学 一种基于Trefftz多源点配点法的稀土矿层地下水渗流模型
EP3698945B1 (en) * 2019-02-22 2022-05-18 Ricoh Company, Ltd. Solid freeform fabrication object, method of manufacturing solid freeform fabrication object, liquid set for solid freeform fabrication, and device for manufacturing solid freeform fabrication object
CN110075934B (zh) * 2019-03-25 2021-06-01 绍兴钠钇光电有限公司 一种3d打印微流控器件及其大通量制备单分散乳液的方法
US12391938B2 (en) 2019-11-26 2025-08-19 T&R Biofab Co., Ltd. Bio-ink supply system and three-dimensional bioprinting method using same
CN111135882B (zh) * 2019-12-30 2021-07-09 南方科技大学 一种二维流动聚焦装置
EP4130236A4 (en) * 2020-04-03 2025-07-16 Jsr Corp METHOD FOR PRODUCING CELL-CONTAINING EXTRACELLULAR MATRIX, CELL CULTURE METHOD, DEVICE FOR PRODUCING CELL-CONTAINING EXTRACELLULAR MATRIX, AND CONTROL PROGRAM
GB202007478D0 (en) * 2020-05-20 2020-07-01 Univ Oxford Innovation Ltd 3D Tissue printing
CN112588218B (zh) * 2020-12-11 2021-09-21 中国科学院力学研究所 一种实现液滴快速自发旋转的方法
CN114103114A (zh) * 2021-11-23 2022-03-01 西安交通大学 一种制备含固体颗粒核壳复合液滴用同轴针头
WO2024227162A1 (en) * 2023-04-28 2024-10-31 Ohio State Innovation Foundation Droplet impact-induced chemical release from structured fluids
CN117464993B (zh) * 2023-10-18 2024-06-14 浙江大学 一种多喷头阵列3d打印梯度孔隙大孔明胶的装置及方法
CN117124597B (zh) * 2023-10-26 2024-01-23 南昌大学 一种细胞微球3d打印路径规划方法
CN120003023B (zh) * 2025-03-27 2025-11-04 西安交通大学 一种高精度单细胞打印仪器及方法

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812856A (en) * 1987-10-30 1989-03-14 Microfab Technologies, Inc. Method and apparatus for dispensing a fluid with dispersed particles therein
US5104736A (en) 1988-03-03 1992-04-14 Micro-Pak, Inc. Reinforced paucilamellar lipid vesicles
US4934564A (en) * 1989-03-23 1990-06-19 Eastman Kodak Company Drop jet metering method and system
US5858399A (en) 1992-04-09 1999-01-12 Northwestern University Acoustically reflective liposomes and methods to make and use the same
US5464629A (en) * 1993-11-16 1995-11-07 Georgetown University Method of forming hydrogel particles having a controlled size using liposomes
US6531156B1 (en) * 1994-04-15 2003-03-11 Temple University Aqueous solven encapsulation method, apparatus and microcapsules
DE4438232A1 (de) * 1994-10-26 1996-05-02 Guenter Prof Dr Fuhr Kryokonservierung und Tieftemperaturbearbeitung von biologischen Zellen
CA2564120C (en) 1997-01-31 2010-04-13 Skyepharma Inc. Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
US5891467A (en) 1997-01-31 1999-04-06 Depotech Corporation Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
US6106858A (en) 1997-09-08 2000-08-22 Skyepharma, Inc. Modulation of drug loading in multivescular liposomes
US7470547B2 (en) * 2003-07-31 2008-12-30 Biodot, Inc. Methods and systems for dispensing sub-microfluidic drops
US6461812B2 (en) * 1998-09-09 2002-10-08 Agilent Technologies, Inc. Method and multiple reservoir apparatus for fabrication of biomolecular arrays
ATE328670T1 (de) * 1999-11-11 2006-06-15 Trinity College Dublin Vorrichtung und verfahren zur verabreichung von tropfen
US20030048341A1 (en) * 2000-09-25 2003-03-13 Mutz Mitchell W. High-throughput biomolecular crystallization and biomolecular crystal screening
US20020106308A1 (en) * 2001-02-02 2002-08-08 Zweifel Ronald A. Microdrop dispensing apparatus
US20030119193A1 (en) * 2001-04-25 2003-06-26 Robert Hess System and method for high throughput screening of droplets
WO2003004280A2 (en) * 2001-07-05 2003-01-16 Creo Srl Improved uniformity ink jet system
US7943067B2 (en) 2001-08-16 2011-05-17 Polytechnic Institute Of New York University Nanogels and their production using liposomes as reactors
US6995024B2 (en) * 2001-08-27 2006-02-07 Sri International Method and apparatus for electrostatic dispensing of microdroplets
US6962747B1 (en) * 2001-10-23 2005-11-08 Sandia Corporation Self-assembled lipid bilayer materials
US6945638B2 (en) * 2001-10-29 2005-09-20 Therics, Inc. Method and system for controlling the temperature of a dispensed liquid
US6960298B2 (en) 2001-12-10 2005-11-01 Nanogen, Inc. Mesoporous permeation layers for use on active electronic matrix devices
US7160614B2 (en) 2002-11-01 2007-01-09 Sony Corporation Crystalline superfine particles, complex material, method of manufacturing crystalline superfine particles, inverted micelles, inverted micelles enveloping precursor superfine particles, inverted micelles enveloping crystalline superfine particles, and precursor superfine particles
US7914714B2 (en) * 2003-05-14 2011-03-29 The Regents Of The University Of Colorado Methods and apparatus using electrostatic atomization to form liquid vesicles
US7051654B2 (en) * 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
US7217410B2 (en) * 2003-06-17 2007-05-15 The Board Of Trustees Of The Universtiy Of Illinois Surface modified protein microparticles
EP1695696A1 (en) 2003-12-01 2006-08-30 Mitsubishi Pharma Corporation Liposome
WO2005069015A1 (ja) 2004-01-15 2005-07-28 Japan Science And Technology Agency 化学分析装置及び化学分析方法
EP1861194A2 (en) 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
US20060210443A1 (en) * 2005-03-14 2006-09-21 Stearns Richard G Avoidance of bouncing and splashing in droplet-based fluid transport
GB0505971D0 (en) * 2005-03-23 2005-04-27 Isis Innovation Delivery of molecules to a lipid bilayer
JP4533805B2 (ja) * 2005-06-06 2010-09-01 株式会社ミマキエンジニアリング 立体メディアプリント用のインクジェットプリンタとそれを用いたプリント方法
JP2007046595A (ja) 2005-07-15 2007-02-22 Daikin Ind Ltd 回転式圧縮機
JP5114702B2 (ja) * 2005-07-29 2013-01-09 国立大学法人 東京大学 両親媒性単分子膜の接触による二分子膜の形成方法およびその装置
US20070148697A1 (en) * 2005-12-27 2007-06-28 Boston Scientific Scimed, Inc. Methods and system for high throughput screening of polymer materials for medical devices
WO2007094739A1 (en) 2006-02-13 2007-08-23 Agency For Science, Technology And Research Method of processing a biological and/or chemical sample
WO2007101174A2 (en) 2006-02-27 2007-09-07 Arizona Board Of Regents For And On Behalf Of Arizona State University Digital magnetofluidic devices and methods
US8492168B2 (en) * 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US7439014B2 (en) * 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US20090208466A1 (en) * 2006-04-21 2009-08-20 James Yoo Ink-jet printing of tissues
US20070293449A1 (en) 2006-06-20 2007-12-20 Nastech Pharmaceutical Company Inc. Compositions and methods for delivery of double-stranded rna
KR100817086B1 (ko) * 2006-07-21 2008-03-26 삼성전자주식회사 비전도성 모세관 노즐을 구비한 전하집중 방식 액적디스펜싱 장치
GB0614835D0 (en) * 2006-07-26 2006-09-06 Isis Innovation Formation of bilayers of amphipathic molecules
EP2064352B1 (en) 2006-09-19 2019-12-04 The Product Makers (Australia) Pty Ltd Extracts derived from sugar cane and a process for their manufacture
EP1920765A1 (en) * 2006-11-07 2008-05-14 Medigene AG Liposome preparation by single-pass process
US7776927B2 (en) * 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
GB0716264D0 (en) 2007-08-21 2007-09-26 Isis Innovation Bilayers
US8293339B2 (en) * 2007-09-17 2012-10-23 Sri International, Inc. Droplet bilayers
WO2009049089A1 (en) 2007-10-09 2009-04-16 Washington University In St. Louis Ligand directed toroidal nanoparticles for therapy and diagnostic imaging
WO2009076414A2 (en) * 2007-12-10 2009-06-18 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods
US20110076734A1 (en) 2008-03-07 2011-03-31 Drexel University Electrowetting Microarray Printing System and Methods for Bioactive Tissue Construct Manufacturing
US9829488B2 (en) * 2008-03-27 2017-11-28 President And Fellows Of Havard College Paper-based cellular arrays
US20110305761A1 (en) * 2008-06-05 2011-12-15 President And Fellows Of Harvard College Polymersomes, colloidosomes, liposomes, and other species associated with fluidic droplets
US9156010B2 (en) * 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
GB0909154D0 (en) * 2008-09-25 2009-07-08 Nanomaterials Tech Pte Ltd A process for making particles for delivery of drug nanoparticles
US20110250688A1 (en) 2008-11-24 2011-10-13 Immunotrex Corporation Three Dimensional Tissue Generation
JP5487666B2 (ja) 2009-03-23 2014-05-07 コニカミノルタ株式会社 内水相を固定化することを特徴とするリポソームの製造方法
WO2010110471A1 (ja) 2009-03-23 2010-09-30 国立大学法人北海道大学 脂質膜構造体
EP2599548B1 (de) 2009-05-13 2018-07-04 ibidi GmbH Probenträger zum Positionieren einer organischen, biologischen und/oder medizinischen Probe
GB0913823D0 (en) 2009-08-07 2009-09-16 Isis Innovation Bilayers
US8992984B1 (en) 2009-10-21 2015-03-31 Stc.Unm Protocells and their use for targeted delivery of multicomponent cargos to cancer cells
ES2671594T3 (es) * 2010-03-04 2018-06-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Puesto de bioimpresión, ensamblaje que comprende dicho puesto de bioimpresión y método de bioimpresión
US20110312759A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Genetic analysis loc with reagent reservoir
US20120006681A1 (en) * 2010-07-06 2012-01-12 Kaler Karan V I S Controlled Dispensing of Ultrafine, Variable Volume, Emulsion Droplets
KR101550941B1 (ko) 2010-10-14 2015-09-07 (주)아모레퍼시픽 리피드가 코팅된 하이드로겔 입자 및 이의 제조방법
CN103167868B (zh) 2010-10-14 2016-08-03 株式会社爱茉莉太平洋 包覆有脂质的水凝胶粒子及其制备方法
KR20160125530A (ko) * 2010-10-21 2016-10-31 오가노보, 인크. 조직의 제작을 위한 디바이스, 시스템 및 방법
JP2012166159A (ja) 2011-02-15 2012-09-06 Microjet:Kk 吐出装置および吐出する方法
CN102655680B (zh) * 2011-03-02 2017-12-15 山东比特智能科技股份有限公司 一种回程链路上发送测量参考信号的方法及系统
US8944083B2 (en) * 2011-06-15 2015-02-03 Ut-Battelle, Llc Generation of monodisperse droplets by shape-induced shear and interfacial controlled fusion of individual droplets on-demand
WO2013041983A1 (en) 2011-09-19 2013-03-28 Centre National De La Recherche Scientifique Microfluidic system
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
US20130319861A1 (en) * 2012-05-30 2013-12-05 Berkeley Lights, Inc. Outputting A Droplet Of Liquid Medium From A Device For Processing Micro-Objects In The Medium
US9223317B2 (en) * 2012-06-14 2015-12-29 Advanced Liquid Logic, Inc. Droplet actuators that include molecular barrier coatings
US20140023697A1 (en) * 2012-07-17 2014-01-23 Iona College Methods and systems for nanomembrane crystallization
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
US9823235B2 (en) * 2012-10-26 2017-11-21 Oxford Nanopre Technologies Ltd. Droplet interfaces
KR102284661B1 (ko) 2012-12-07 2021-08-02 옥스포드 유니버시티 이노베이션 리미티드 3d 프린팅에 의한 비말 어셈블리

Also Published As

Publication number Publication date
US11213797B2 (en) 2022-01-04
KR102449271B1 (ko) 2022-09-29
CN105188934B (zh) 2018-12-04
KR102284661B1 (ko) 2021-08-02
EP2928610A2 (en) 2015-10-14
CN105188934A (zh) 2015-12-23
US20160136888A1 (en) 2016-05-19
KR20210096318A (ko) 2021-08-04
US20220072497A1 (en) 2022-03-10
JP2016508076A (ja) 2016-03-17
JP2019031094A (ja) 2019-02-28
WO2014087175A2 (en) 2014-06-12
KR20150094684A (ko) 2015-08-19
JP6782746B2 (ja) 2020-11-11
WO2014087175A3 (en) 2014-08-07

Similar Documents

Publication Publication Date Title
JP6416772B2 (ja) ３ｄプリンティングによる小滴集合
Booth et al. Functional aqueous droplet networks
Holden et al. Functional bionetworks from nanoliter water droplets
Trantidou et al. Engineering compartmentalized biomimetic micro-and nanocontainers
EP2047266B1 (en) Formation of bilayers of amphipathic molecules
Mouritsen et al. Life-as a matter of fat: lipids in a membrane biophysics perspective
US9831010B2 (en) Hydrogel network
Lopez et al. Enthalpic effects of chain length and unsaturation on water permeability across droplet bilayers of homologous monoglycerides
Berganza et al. Direct-write patterning of biomimetic lipid membranes in situ with fluidfm
Lee Good to the last drop: interfacial droplet chemistry, from crystals to biological membranes
Hirono et al. Locomotion mode of micrometer-sized oil droplets in solutions of cationic surfactants having ester or ether linkages
Nguindjel et al. Reconfigurable droplet–droplet communication mediated by photochemical marangoni flows
JP7094886B2 (ja) 改良されたプロモーター及び組成物
JP2004509778A (ja) コンテナおよびナノチューブの微細ネットワーク
Villar Aqueous droplet networks for functional tissue-like materials
EP3513190B1 (en) Artificial cells
Muñuzuri et al. Osmotically Induced Membrane Fission in Giant Polymer Vesicles: Multilamellarity and Effect of the Amphiphilic Block Lengths
Zhao Synthetic membranes in microfluidic interfaces
Kataoka-Hamai et al. Hydrocarbon Penetration into Phospholipid Monolayers Formed at Hydrocarbon–Water Interfaces
Keith Using Agarose-Assisted Formation as an Alternative to Electroformation for Producing Phase Separating Vesicles
Su Compartments and Crowding: Biophysical Features of Living Cells
Elias Microfluidics to characterize and manipulate biomimetic membranes
Wegrzyn et al. Nanotube-interconnected liposome networks
Lu Continuous microfluidic fabrication and measurement of membrane mechanical properties of synthetic asymmetric vesicles
Majumdar Mechanical characterization of droplet interface bilayer encapsulatedin a soft polymer

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20150810

RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20150810

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161206

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20161206

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180216

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180227

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180528

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180627

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180904

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20181004

R150 Certificate of patent or registration of utility model

Ref document number: 6416772

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250