JP6407174B2 - 抗体の配合物および該配合物の使用 - Google Patents
抗体の配合物および該配合物の使用 Download PDFInfo
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- JP6407174B2 JP6407174B2 JP2015562255A JP2015562255A JP6407174B2 JP 6407174 B2 JP6407174 B2 JP 6407174B2 JP 2015562255 A JP2015562255 A JP 2015562255A JP 2015562255 A JP2015562255 A JP 2015562255A JP 6407174 B2 JP6407174 B2 JP 6407174B2
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- histidine
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361787225P | 2013-03-15 | 2013-03-15 | |
| EP13159325 | 2013-03-15 | ||
| EP13159325.3 | 2013-03-15 | ||
| US61/787,225 | 2013-03-15 | ||
| PCT/EP2014/055279 WO2014140361A1 (en) | 2013-03-15 | 2014-03-17 | Formulation of an antibody and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512218A JP2016512218A (ja) | 2016-04-25 |
| JP2016512218A5 JP2016512218A5 (enExample) | 2017-04-20 |
| JP6407174B2 true JP6407174B2 (ja) | 2018-10-17 |
Family
ID=47900830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562255A Active JP6407174B2 (ja) | 2013-03-15 | 2014-03-17 | 抗体の配合物および該配合物の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11433029B2 (enExample) |
| EP (1) | EP2970465B1 (enExample) |
| JP (1) | JP6407174B2 (enExample) |
| CN (1) | CN105189559B (enExample) |
| CA (1) | CA2903611C (enExample) |
| WO (1) | WO2014140361A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6594272B2 (ja) * | 2016-09-02 | 2019-10-23 | 株式会社東芝 | 半導体装置及びその製造方法 |
| CN110022855B (zh) * | 2016-10-07 | 2024-07-16 | 瑞泽恩制药公司 | 室温稳定的冻干蛋白质 |
| US20210388112A1 (en) * | 2018-07-09 | 2021-12-16 | National University Corporation Kumamoto University | Cyclic Single-Chain Antibody |
| CA3122902A1 (en) * | 2018-12-14 | 2020-06-18 | Morphosys Ag | Antibody formulations |
| CR20210435A (es) | 2019-02-18 | 2021-09-20 | Lilly Co Eli | Formulación de anticuerpos terapéuticos |
| RU2754760C2 (ru) * | 2019-04-02 | 2021-09-07 | Закрытое Акционерное Общество "Биокад" | Водная фармацевтическая композиция анти-il17a антитела и ее применение |
| CN112675126A (zh) * | 2019-10-18 | 2021-04-20 | 百奥泰生物制药股份有限公司 | 抗cd20抗体制剂及其应用 |
| US20230338526A1 (en) * | 2019-10-12 | 2023-10-26 | Bio-Thera Solutions, Ltd. | Anti-cd20 antibody formulation and use of anti-cd20 antibody for treatment of cd20 positive diseases |
| CN113082203B (zh) * | 2020-01-09 | 2023-10-20 | 鲁南制药集团股份有限公司 | 一种免疫抑制剂单克隆抗体的液体制剂 |
| CN116782889A (zh) * | 2020-11-16 | 2023-09-19 | 生物技术欧洲股份公司 | 增强的制剂稳定性和改善的冻干工艺 |
| WO2022101461A1 (en) * | 2020-11-16 | 2022-05-19 | BioNTech SE | Enhanced formulation stabilization and improved lyophilization processes |
| CN113855798A (zh) * | 2021-09-30 | 2021-12-31 | 佛山汉腾生物科技有限公司 | 抗cd20的抗体制剂 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| ES2434840T3 (es) * | 1995-07-27 | 2013-12-17 | Genentech, Inc. | Formulación de proteína liofilizada isotónica estable |
| JP4317010B2 (ja) | 2001-07-25 | 2009-08-19 | ピーディーエル バイオファーマ，インコーポレイティド | ＩｇＧ抗体の安定な凍結乾燥医薬製剤 |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| CA2612937C (en) * | 2005-07-22 | 2014-05-06 | Amgen Inc. | Concentrated protein lyophilates, methods, and uses |
| US20090208492A1 (en) | 2007-06-14 | 2009-08-20 | Elan Pharmaceuticals, Inc. | Lyophilized Immunoglobulin Formulations and Methods of Preparation |
| WO2009007272A1 (en) * | 2007-07-10 | 2009-01-15 | F. Hoffmann-La Roche Ag | Novel formulation |
| EP2234600B1 (en) | 2007-12-21 | 2014-08-20 | F. Hoffmann-La Roche AG | Antibody formulation |
| BRPI0917204A2 (pt) * | 2008-07-21 | 2015-12-01 | Immunomedics Inc | variantes estruturais de anticorpos para melhores características terapêuticas |
| EP2323629B1 (en) | 2008-08-05 | 2019-10-09 | Wyeth LLC | Lyophilization above collapse |
| WO2010148321A1 (en) | 2009-06-18 | 2010-12-23 | Wyeth Llc | Slow dissolution method for reconstitution of lyophilized material |
| EP2442798A4 (en) * | 2009-06-18 | 2013-03-13 | Wyeth Llc | LYOPHILIZED FORMULATIONS FOR SMALL-SCALE MODULAR IMMUNOPHARMACEUTICAL AGENTS |
| EP2458990B1 (en) | 2009-07-28 | 2016-03-30 | Merck Sharp & Dohme Corp. | Methods for producing high concentration lyophilized pharmaceutical formulations |
| AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
| EP2704751B1 (en) * | 2011-05-02 | 2019-04-17 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
| EP2727602A1 (en) | 2012-10-31 | 2014-05-07 | Takeda GmbH | Method for preparation of a high concentration liquid formulation of an antibody |
-
2014
- 2014-03-17 EP EP14710314.7A patent/EP2970465B1/en active Active
- 2014-03-17 US US14/773,478 patent/US11433029B2/en active Active
- 2014-03-17 CA CA2903611A patent/CA2903611C/en active Active
- 2014-03-17 JP JP2015562255A patent/JP6407174B2/ja active Active
- 2014-03-17 US US14/215,816 patent/US11576863B2/en active Active
- 2014-03-17 CN CN201480025774.8A patent/CN105189559B/zh active Active
- 2014-03-17 WO PCT/EP2014/055279 patent/WO2014140361A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20160022585A1 (en) | 2016-01-28 |
| US11433029B2 (en) | 2022-09-06 |
| US20140271636A1 (en) | 2014-09-18 |
| CN105189559A (zh) | 2015-12-23 |
| JP2016512218A (ja) | 2016-04-25 |
| WO2014140361A1 (en) | 2014-09-18 |
| US11576863B2 (en) | 2023-02-14 |
| CN105189559B (zh) | 2021-07-13 |
| EP2970465A1 (en) | 2016-01-20 |
| CA2903611C (en) | 2023-11-07 |
| EP2970465B1 (en) | 2019-09-25 |
| CA2903611A1 (en) | 2014-09-18 |
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