JP6370490B2 - 免疫抑制活性なしに神経再生活性が維持されるｆｋ５０６誘導体及びその用途 - Google Patents

免疫抑制活性なしに神経再生活性が維持されるｆｋ５０６誘導体及びその用途 Download PDF

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JP6370490B2
JP6370490B2 JP2017526030A JP2017526030A JP6370490B2 JP 6370490 B2 JP6370490 B2 JP 6370490B2 JP 2017526030 A JP2017526030 A JP 2017526030A JP 2017526030 A JP2017526030 A JP 2017526030A JP 6370490 B2 JP6370490 B2 JP 6370490B2
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deoxo
prolyl
streptomyces
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JP2017523241A (ja
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ジョオン ヨオン イエオ
ジョオン ヨオン イエオ
ジェオング クウオン ホ
ジェオング クウオン ホ
ヘエ バン イエオン
ヘエ バン イエオン
プラモドブ シンデ
プラモドブ シンデ
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イントロン バイオテクノロジー シーオー．，エルティーディー
イントロン バイオテクノロジー シーオー．，エルティーディー
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JP2017526030A 2014-08-01 2015-07-31 免疫抑制活性なしに神経再生活性が維持されるｆｋ５０６誘導体及びその用途 Active JP6370490B2 (ja)

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KR10-2014-0099210 2014-08-01
KR1020140099210A KR101694879B1 (ko) 2014-08-01 2014-08-01 면역억제활성 없이 신경재생활성이 유지되는 fk506 유도체 및 그의 용도
PCT/KR2015/008031 WO2016018117A1 (ko) 2014-08-01 2015-07-31 면역억제활성 없이 신경재생활성이 유지되는 fk506 유도체 및 그의 용도

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JP2018012496A Division JP6851334B2 (ja) 2014-08-01 2018-01-29 免疫抑制活性なしに神経再生活性が維持されるｆｋ５０６誘導体及びその用途

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JP2018012496A Active JP6851334B2 (ja) 2014-08-01 2018-01-29 免疫抑制活性なしに神経再生活性が維持されるｆｋ５０６誘導体及びその用途

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US (2) US10226446B2 (enExample)
EP (1) EP3187183B1 (enExample)
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KR101694879B1 (ko) * 2014-08-01 2017-01-12 주식회사 인트론바이오테크놀로지 면역억제활성 없이 신경재생활성이 유지되는 fk506 유도체 및 그의 용도
CN113939519B (zh) * 2018-12-11 2025-02-14 莫尔根生物有限公司 促进毛发生长的新化合物及包含它们的组合物
US11449807B2 (en) 2020-01-31 2022-09-20 Walmart Apollo, Llc Systems and methods for bootstrapped machine learning algorithm training
WO2021256894A1 (ko) * 2020-06-19 2021-12-23 서울대학교 산학협력단 신경 돌기 생장 및 시냅스 형성 활성을 갖는 신규 prolylfk506 유도체 및 그의 용도
CN118460433B (zh) * 2024-06-04 2026-01-06 浙江启臻合成生物技术有限公司 生产他克莫司的链霉菌工程菌及其构建方法与应用

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US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
EP1595541A1 (en) * 2004-05-12 2005-11-16 Alcasynn Pharmaceuticals Gmbh Use of opioid receptor antagonist compounds for the prevention and/or treatment of diseases associated with the target calcineurin
MX2009006958A (es) * 2006-12-28 2009-07-09 Limerick Biopharma Inc Metodos y composiciones para tratamiento terapeutico.
WO2009158031A2 (en) * 2008-06-27 2009-12-30 Limerick Biopharma, Inc. Methods and compositions for therapeutic treatment
KR101261131B1 (ko) 2010-08-24 2013-05-06 이화여자대학교 산학협력단 신규 타크롤리무스 유도체, 상기 유도체를 포함하는 신경 보호용 조성물, 상기 유도체를 포함하는 면역 억제용 조성물, 상기 유도체의 생산 방법 및 상기 유도체의 생산 균주
KR101632042B1 (ko) * 2014-06-30 2016-06-21 주식회사 인트론바이오테크놀로지 Fk506 유도체를 함유하는 크립토코쿠스 속 곰팡이 및 칸디다 속 곰팡이에 의한 진균 감염을 치료하기 위한 약제학적 조성물 및 그의 용도
KR101694879B1 (ko) * 2014-08-01 2017-01-12 주식회사 인트론바이오테크놀로지 면역억제활성 없이 신경재생활성이 유지되는 fk506 유도체 및 그의 용도

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EP3187183A1 (en) 2017-07-05
JP2017523241A (ja) 2017-08-17
US10226446B2 (en) 2019-03-12
WO2016018117A1 (ko) 2016-02-04
KR101694879B1 (ko) 2017-01-12
KR20160017267A (ko) 2016-02-16
EP3187183B1 (en) 2020-04-08
CN110251511A (zh) 2019-09-20
CN106794169B (zh) 2020-02-04
US20170216254A1 (en) 2017-08-03
EP3187183A4 (en) 2018-03-21
JP6851334B2 (ja) 2021-03-31
US20190134001A1 (en) 2019-05-09
US10576060B2 (en) 2020-03-03
JP2018083843A (ja) 2018-05-31
CN106794169A (zh) 2017-05-31

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