JP6363595B2 - 歯周炎および歯周炎に関連する疾患を処置または予防する方法 - Google Patents

歯周炎および歯周炎に関連する疾患を処置または予防する方法 Download PDF

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JP6363595B2
JP6363595B2 JP2015518554A JP2015518554A JP6363595B2 JP 6363595 B2 JP6363595 B2 JP 6363595B2 JP 2015518554 A JP2015518554 A JP 2015518554A JP 2015518554 A JP2015518554 A JP 2015518554A JP 6363595 B2 JP6363595 B2 JP 6363595B2
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periodontitis
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porphyromonas gingivalis
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ジョージ・ハジシェンガリス
ジョン・ディ・ランブリス
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders

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JP2015518554A 2012-06-20 2013-06-19 歯周炎および歯周炎に関連する疾患を処置または予防する方法 Active JP6363595B2 (ja)

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US201261662022P 2012-06-20 2012-06-20
US61/662,022 2012-06-20
US13/801,096 2013-03-13
US13/801,096 US9579360B2 (en) 2012-06-20 2013-03-13 Methods of treating or preventing periodontitis and diseases associated with periodontitis
PCT/US2013/046599 WO2013192319A1 (en) 2012-06-20 2013-06-19 Methods of treating or preventing periodontitis and diseases associated with periodontitis

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JP2015523999A JP2015523999A (ja) 2015-08-20
JP6363595B2 true JP6363595B2 (ja) 2018-07-25

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US (2) US9579360B2 (OSRAM)
EP (1) EP2863949B1 (OSRAM)
JP (1) JP6363595B2 (OSRAM)
CN (1) CN104640567A (OSRAM)
AU (1) AU2013277217B2 (OSRAM)
CA (1) CA2877299C (OSRAM)
IN (1) IN2015DN00438A (OSRAM)
WO (1) WO2013192319A1 (OSRAM)

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CA2847862C (en) 2011-09-07 2021-01-12 The Trustees Of The University Of Pennsylvania Compstatin analogs with improved pharmacokinetic properties
US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
MX373962B (es) 2014-02-25 2020-07-13 Achillion Pharmaceuticals Inc Compuestos arilo, heteroarilo y heterociclicos para el tratamiento de trastornos mediados por complemento.
RS59353B1 (sr) 2014-06-12 2019-10-31 Ra Pharmaceuticals Inc Modulacija aktivnosti komplementa
HUE056613T2 (hu) 2015-01-28 2022-02-28 Ra Pharmaceuticals Inc Komplementaktivitás modulátorai
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
WO2017035401A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amide compounds for treatment of immune and inflammatory disorders
WO2017035409A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
WO2017035405A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amino compounds for treatment of immune and inflammatory disorders
AU2016370210A1 (en) 2015-12-16 2018-06-21 Ra Pharmaceuticals, Inc. Modulators of complement activity
WO2018106859A1 (en) 2016-12-07 2018-06-14 Ra Pharmaceuticals, Inc. Modulators of complement activity
PT3985002T (pt) 2017-03-01 2025-08-29 Achillion Pharmaceuticals Inc Compostos farmacêuticos de arilo, heteroarilo e heterocíclicos para tratamento de distúrbios médicos
WO2018160891A1 (en) 2017-03-01 2018-09-07 Achillion Pharmaceutical, Inc. Pharmaceutical compounds for treatment of medical disorders
WO2019028284A1 (en) 2017-08-02 2019-02-07 Achillion Pharmaceuticals, Inc. THERAPEUTIC REGIMES FOR THE TREATMENT OF NOCTURNAL PAROXYSTIC HEMOGLOBINURIA
EP3720463A1 (en) 2017-12-04 2020-10-14 RA Pharmaceuticals, Inc. Modulators of complement activity
MA51162A (fr) * 2017-12-15 2020-10-21 Apellis Pharmaceuticals Inc Schémas posologiques et compositions et procédés associés
BR112020020369A2 (pt) 2018-04-06 2021-01-19 The Trustees Of The University Of Pennsylvania Análogos de compstatina com aumento de solubilidade e propriedades farmacocinéticas melhoradas
WO2020051532A2 (en) 2018-09-06 2020-03-12 Achillion Pharmaceuticals, Inc. Macrocyclic compounds for the treatment of medical disorders
US11814363B2 (en) 2018-09-06 2023-11-14 Achillion Pharmaceuticals, Inc. Morphic forms of danicopan
US11807627B2 (en) 2018-09-25 2023-11-07 Achillon Pharmaceuticals, Inc. Morphic forms of complement factor D inhibitors
CA3123583A1 (en) 2018-12-17 2020-06-25 Achillion Pharmaceuticals, Inc. Targeted dosing for the treatment of complement mediated disorders
US20220160820A1 (en) 2019-03-08 2022-05-26 Ra Pharmaceuticals, Inc. Modulators of complement activity
BR112021018456A2 (pt) 2019-03-22 2021-11-23 Achillion Pharmaceuticals Inc Compostos farmacêuticos para o tratamento de distúrbios mediados por complemento
TW202102481A (zh) 2019-03-29 2021-01-16 美商Ｒａ製藥公司 補體調節劑和相關方法
TW202106290A (zh) 2019-04-24 2021-02-16 美商Ｒａ製藥公司 用於調節補體活性之組成物及方法

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US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis

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WO2013192319A1 (en) 2013-12-27
US9579360B2 (en) 2017-02-28
AU2013277217A2 (en) 2015-01-22
CN104640567A (zh) 2015-05-20
JP2015523999A (ja) 2015-08-20
AU2013277217A1 (en) 2015-01-22
US10668135B2 (en) 2020-06-02
EP2863949A1 (en) 2015-04-29
IN2015DN00438A (OSRAM) 2015-06-19
CA2877299A1 (en) 2013-12-27
AU2013277217B2 (en) 2018-03-08
EP2863949B1 (en) 2019-01-23
US20130344082A1 (en) 2013-12-26
EP2863949A4 (en) 2016-03-02
CA2877299C (en) 2022-07-12
US20170202935A1 (en) 2017-07-20

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