CA2877299C - Methods of treating or preventing periodontitis and diseases associated with periodontitis - Google Patents
Methods of treating or preventing periodontitis and diseases associated with periodontitis Download PDFInfo
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- CA2877299C CA2877299C CA2877299A CA2877299A CA2877299C CA 2877299 C CA2877299 C CA 2877299C CA 2877299 A CA2877299 A CA 2877299A CA 2877299 A CA2877299 A CA 2877299A CA 2877299 C CA2877299 C CA 2877299C
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- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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| PCT/US2013/046599 WO2013192319A1 (en) | 2012-06-20 | 2013-06-19 | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
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| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
| DK3110418T3 (da) | 2014-02-25 | 2020-02-10 | Achillion Pharmaceuticals Inc | Aryl-, heteroaryl- og heterocykliske-forbindelser til behandling af komplemt-medierede lidelser |
| BR122023024819A2 (pt) | 2014-06-12 | 2023-12-26 | Ra Pharmaceuticals, Inc. | Uso de um polipeptídeo para inibir a clivagem de c5 em um sistema celular |
| EP3988110A1 (en) | 2015-01-28 | 2022-04-27 | RA Pharmaceuticals, Inc. | Modulators of complement activity |
| WO2017035409A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| SG11201804721SA (en) | 2015-12-16 | 2018-07-30 | Ra Pharmaceuticals Inc | Modulators of complement activity |
| EP3551210A1 (en) | 2016-12-07 | 2019-10-16 | RA Pharmaceuticals, Inc. | Modulators of complement activity |
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| US20190038623A1 (en) | 2017-08-02 | 2019-02-07 | Achillion Pharmaceuticals, Inc. | Therapeutic regimens for treatment of paroxysmal nocturnal hemoglobinuria |
| KR20200095485A (ko) | 2017-12-04 | 2020-08-10 | 라 파마슈티컬스 인코포레이티드 | 보체 활성의 조절인자 |
| EP3724211A4 (en) | 2017-12-15 | 2021-10-27 | Apellis Pharmaceuticals, Inc. | DOSAGE SCHEDULES AND ASSOCIATED COMPOSITIONS AND PROCESSES |
| EP3645550B1 (en) | 2018-04-06 | 2021-11-03 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with increased solubility and improved pharmacokinetic properties |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| CN112839945A (zh) | 2018-09-06 | 2021-05-25 | 艾其林医药公司 | 补体因子d抑制剂的形态形式 |
| CN112996497A (zh) | 2018-09-25 | 2021-06-18 | 艾其林医药公司 | 补体因子d抑制剂的形态形式 |
| MX2021007329A (es) | 2018-12-17 | 2021-09-21 | Achillion Pharmaceuticals Inc | Dosificacion dirigida para el tratamiento de trastornos mediados por el complemento. |
| EP3934675A2 (en) | 2019-03-08 | 2022-01-12 | RA Pharmaceuticals, Inc. | Zilucoplan as deep tissue penetrating c5 inhibitor |
| JP2022527508A (ja) | 2019-03-29 | 2022-06-02 | ラ ファーマシューティカルズ インコーポレイテッド | 補体モジュレータ及び関連方法 |
| CN113710230A (zh) | 2019-04-24 | 2021-11-26 | Ra制药公司 | 用于调节补体活性的组合物和方法 |
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| AU2010242739B2 (en) * | 2009-05-01 | 2016-08-25 | The Trustees Of The University Of Pennsylvania | Modified compstatin with peptide backbone and C-terminal modifications |
| WO2010132954A1 (en) | 2009-05-21 | 2010-11-25 | Oral Health Australia Pty Ltd | Method of treating periodontal disease by administering antagonists of par-2 |
| AU2010298157A1 (en) * | 2009-09-23 | 2012-04-12 | The Regents Of The University Of Colorado, A Body Corporate | Toll-like receptor modulators and uses thereof |
| EP2525814A4 (en) | 2010-01-22 | 2013-09-11 | Univ Louisville Res Found | METHODS OF TREATING OR PREVENTING PERIODONTITIS AND PARODONTIST-RELATED DISEASES |
| WO2011115225A1 (ja) * | 2010-03-17 | 2011-09-22 | 国立大学法人 鹿児島大学 | 歯周病特異的ペプチド、並びにそれを用いた歯周病の治療および診断 |
| EP3524258B1 (en) * | 2011-06-22 | 2025-10-01 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
| PT2753636T (pt) * | 2011-09-07 | 2020-01-21 | Univ Pennsylvania | Análogos de compstatina com propriedades farmacocinéticas melhoradas |
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| JP6363595B2 (ja) | 2018-07-25 |
| EP2863949A1 (en) | 2015-04-29 |
| CN104640567A (zh) | 2015-05-20 |
| JP2015523999A (ja) | 2015-08-20 |
| IN2015DN00438A (OSRAM) | 2015-06-19 |
| US9579360B2 (en) | 2017-02-28 |
| CA2877299A1 (en) | 2013-12-27 |
| US10668135B2 (en) | 2020-06-02 |
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