JP6338530B2 - アルツハイマー病を治療、診断、および監視するための方法 - Google Patents
アルツハイマー病を治療、診断、および監視するための方法 Download PDFInfo
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- JP6338530B2 JP6338530B2 JP2014541330A JP2014541330A JP6338530B2 JP 6338530 B2 JP6338530 B2 JP 6338530B2 JP 2014541330 A JP2014541330 A JP 2014541330A JP 2014541330 A JP2014541330 A JP 2014541330A JP 6338530 B2 JP6338530 B2 JP 6338530B2
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558197P | 2011-11-10 | 2011-11-10 | |
| US61/558,197 | 2011-11-10 | ||
| US201261671531P | 2012-07-13 | 2012-07-13 | |
| US61/671,531 | 2012-07-13 | ||
| PCT/US2012/064466 WO2013071119A2 (en) | 2011-11-10 | 2012-11-09 | Methods for treating, diagnosing and monitoring alzheimer's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018090050A Division JP2018166507A (ja) | 2011-11-10 | 2018-05-08 | アルツハイマー病を治療、診断、および監視するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533949A JP2014533949A (ja) | 2014-12-18 |
| JP2014533949A5 JP2014533949A5 (enExample) | 2016-01-07 |
| JP6338530B2 true JP6338530B2 (ja) | 2018-06-06 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541330A Expired - Fee Related JP6338530B2 (ja) | 2011-11-10 | 2012-11-09 | アルツハイマー病を治療、診断、および監視するための方法 |
| JP2018090050A Pending JP2018166507A (ja) | 2011-11-10 | 2018-05-08 | アルツハイマー病を治療、診断、および監視するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018090050A Pending JP2018166507A (ja) | 2011-11-10 | 2018-05-08 | アルツハイマー病を治療、診断、および監視するための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20140371094A1 (enExample) |
| EP (1) | EP2776582A2 (enExample) |
| JP (2) | JP6338530B2 (enExample) |
| KR (1) | KR20140089384A (enExample) |
| CN (3) | CN105063186A (enExample) |
| AR (1) | AR088827A1 (enExample) |
| BR (1) | BR112014011127A2 (enExample) |
| CA (1) | CA2854779A1 (enExample) |
| HK (1) | HK1214631A1 (enExample) |
| MX (1) | MX2014005683A (enExample) |
| RU (1) | RU2014123511A (enExample) |
| WO (1) | WO2013071119A2 (enExample) |
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| US7702468B2 (en) | 2006-05-03 | 2010-04-20 | Population Diagnostics, Inc. | Evaluating genetic disorders |
| US10522240B2 (en) | 2006-05-03 | 2019-12-31 | Population Bio, Inc. | Evaluating genetic disorders |
| WO2012018387A2 (en) | 2010-08-02 | 2012-02-09 | Population Diagnotics, Inc. | Compositions and methods for discovery of causative mutations in genetic disorders |
| CA2851388C (en) | 2011-10-10 | 2023-11-21 | The Hospital For Sick Children | Methods and compositions for screening and treating developmental disorders |
| US11180807B2 (en) | 2011-11-04 | 2021-11-23 | Population Bio, Inc. | Methods for detecting a genetic variation in attractin-like 1 (ATRNL1) gene in subject with Parkinson's disease |
| EP2812452B1 (en) | 2012-02-09 | 2020-05-27 | Population Bio, Inc. | Methods and compositions for screening and treating developmental disorders |
| US9976180B2 (en) | 2012-09-14 | 2018-05-22 | Population Bio, Inc. | Methods for detecting a genetic variation in subjects with parkinsonism |
| WO2014052855A1 (en) | 2012-09-27 | 2014-04-03 | Population Diagnostics, Inc. | Methods and compositions for screening and treating developmental disorders |
| US11089959B2 (en) | 2013-03-15 | 2021-08-17 | I2Dx, Inc. | Electronic delivery of information in personalized medicine |
| US9782075B2 (en) | 2013-03-15 | 2017-10-10 | I2Dx, Inc. | Electronic delivery of information in personalized medicine |
| EP3077533B1 (en) * | 2013-12-06 | 2019-04-24 | Life & Brain GmbH | Methods for establishing a clinical prognosis of diseases associated with the formation of aggregates of abeta1-42 |
| CA2996445A1 (en) | 2014-09-05 | 2016-03-10 | Eli Hatchwell | Methods and compositions for inhibiting and treating neurological conditions |
| WO2016050111A1 (en) * | 2014-09-30 | 2016-04-07 | Bgi Shenzhen | Biomarkers for rheumatoid arthritis and usage thereof |
| US11756655B2 (en) * | 2015-10-09 | 2023-09-12 | Guardant Health, Inc. | Population based treatment recommender using cell free DNA |
| JP2017189121A (ja) * | 2016-04-11 | 2017-10-19 | 国立大学法人旭川医科大学 | 抗TNFα抗体適応疾患の治療における抗TNFα抗体投与時反応の発症リスクを判定する方法、並びに該判定用オリゴヌクレオチドキット |
| KR102024862B1 (ko) * | 2016-10-19 | 2019-09-25 | 삼성디스플레이 주식회사 | 표시 장치 |
| US11725232B2 (en) * | 2016-10-31 | 2023-08-15 | The Hong Kong University Of Science And Technology | Compositions, methods and kits for detection of genetic variants for alzheimer's disease |
| US10240205B2 (en) | 2017-02-03 | 2019-03-26 | Population Bio, Inc. | Methods for assessing risk of developing a viral disease using a genetic test |
| EP3626830A4 (en) * | 2017-05-15 | 2021-01-27 | Infomeditech Co., Ltd. | SINGLE NUCLEOTIDE POLYMORPHISM OF AN APOE PROMOTER RELATED TO ALZHEIMER'S MORBUS AND USE OF IT |
| EP3764902A4 (en) * | 2018-03-13 | 2021-12-08 | I2Dx, Inc. | ELECTRONIC PROVISION OF INFORMATION IN PERSONALIZED MEDICINE |
| CN108753954B (zh) * | 2018-06-26 | 2022-11-18 | 中南大学湘雅医院 | 痴呆相关基因的捕获探针组、试剂盒、文库构建方法和用途 |
| FI4417708T3 (fi) | 2018-08-08 | 2025-12-04 | Pml Screening Llc | Menetelmiä virustaudin kehittymisen riskin arvioimiseksi geneettisen testin avulla |
| WO2020143044A1 (zh) * | 2019-01-11 | 2020-07-16 | 深圳市双科生物科技有限公司 | 一种双质控检测方法 |
| KR20200130165A (ko) * | 2019-05-10 | 2020-11-18 | 주식회사 엠제이브레인바이오 | Top3b 유전자 변이 기반 치매 진단방법 |
| CN118703617A (zh) * | 2019-08-29 | 2024-09-27 | 香港科技大学 | 用于诊断阿尔茨海默病的遗传变体 |
| GB202004832D0 (en) * | 2020-04-01 | 2020-05-13 | Instituto De Medicina Molecular Faculdade De Medicina Univ De Lisboa | Therapeutic agaents, pharmaceutical compositions, and associated biomarkers |
| KR102561438B1 (ko) * | 2020-11-04 | 2023-07-28 | 사회복지법인 삼성생명공익재단 | 뇌 아밀로이드 베타 축적 가능성을 예측하는 방법 |
| CN112980954B (zh) * | 2021-03-03 | 2022-02-25 | 首都医科大学宣武医院 | 一种预测神经退行性疾病风险的试剂盒及其用途 |
| AU2024207916A1 (en) * | 2023-01-09 | 2025-07-17 | Alchemab Therapeutics Ltd | Anti-unc5c antibodies |
| CN117230184B (zh) * | 2023-11-13 | 2024-03-19 | 深圳康美生物科技股份有限公司 | 基于飞行时间核酸质谱技术检测阿尔兹海默病基因的核酸组合及应用 |
| WO2025125898A1 (en) * | 2023-12-15 | 2025-06-19 | Alchemab Therapeutics Ltd | Anti-unc5c antibodies and uses thereof |
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| US5498531A (en) | 1993-09-10 | 1996-03-12 | President And Fellows Of Harvard College | Intron-mediated recombinant techniques and reagents |
| WO1997045559A1 (en) | 1996-05-29 | 1997-12-04 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
| JP2004507226A (ja) | 2000-05-30 | 2004-03-11 | ピーイー コーポレイション (エヌワイ) | ライゲーションおよび増幅の組み合わせを用いて標的核酸を検出するための方法 |
| US6514221B2 (en) | 2000-07-27 | 2003-02-04 | Brigham And Women's Hospital, Inc. | Blood-brain barrier opening |
| US20030083299A1 (en) | 2000-11-04 | 2003-05-01 | Ferguson Ian A. | Non-invasive delivery of polypeptides through the blood-brain barrier |
| DE10121982B4 (de) | 2001-05-05 | 2008-01-24 | Lts Lohmann Therapie-Systeme Ag | Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung |
| US20030119004A1 (en) | 2001-12-05 | 2003-06-26 | Wenz H. Michael | Methods for quantitating nucleic acids using coupled ligation and amplification |
| CN100386068C (zh) | 2002-12-03 | 2008-05-07 | 布朗歇特洛克菲勒神经科学研究所 | 传输物质穿过血脑屏障的人工低密度脂蛋白载体 |
| CA2722314C (en) * | 2008-04-29 | 2018-01-02 | Pharnext | New therapeutic approaches for treating alzheimer disease and related disorders through a modulation of cell stress response |
| CN101812525A (zh) * | 2010-04-09 | 2010-08-25 | 南通大学 | 与ad发病相关的基因网络通路分析模型的建立方法 |
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| Publication number | Publication date |
|---|---|
| WO2013071119A2 (en) | 2013-05-16 |
| CN105063186A (zh) | 2015-11-18 |
| CN103930568A (zh) | 2014-07-16 |
| CN106011243A (zh) | 2016-10-12 |
| BR112014011127A2 (pt) | 2017-05-16 |
| HK1214631A1 (zh) | 2016-07-29 |
| US20140371094A1 (en) | 2014-12-18 |
| KR20140089384A (ko) | 2014-07-14 |
| AR088827A1 (es) | 2014-07-10 |
| CA2854779A1 (en) | 2013-05-16 |
| JP2018166507A (ja) | 2018-11-01 |
| RU2014123511A (ru) | 2015-12-20 |
| WO2013071119A3 (en) | 2013-07-11 |
| EP2776582A2 (en) | 2014-09-17 |
| JP2014533949A (ja) | 2014-12-18 |
| MX2014005683A (es) | 2015-01-22 |
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