JP6336697B2 - 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 - Google Patents
少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 Download PDFInfo
- Publication number
- JP6336697B2 JP6336697B2 JP2015523264A JP2015523264A JP6336697B2 JP 6336697 B2 JP6336697 B2 JP 6336697B2 JP 2015523264 A JP2015523264 A JP 2015523264A JP 2015523264 A JP2015523264 A JP 2015523264A JP 6336697 B2 JP6336697 B2 JP 6336697B2
- Authority
- JP
- Japan
- Prior art keywords
- hematocrit
- blood
- centrifuge
- sample
- interface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/10—Image acquisition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/011—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
- G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
- G01N2015/055—Investigating sedimentation of particle suspensions in blood for hematocrite determination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Multimedia (AREA)
- Theoretical Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261673037P | 2012-07-18 | 2012-07-18 | |
| US61/673,037 | 2012-07-18 | ||
| PCT/US2013/051143 WO2014015177A1 (en) | 2012-07-18 | 2013-07-18 | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017215430A Division JP2018021936A (ja) | 2012-07-18 | 2017-11-08 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015528910A JP2015528910A (ja) | 2015-10-01 |
| JP2015528910A5 JP2015528910A5 (enExample) | 2016-09-08 |
| JP6336697B2 true JP6336697B2 (ja) | 2018-06-06 |
Family
ID=49945429
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015523264A Expired - Fee Related JP6336697B2 (ja) | 2012-07-18 | 2013-07-18 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
| JP2017215430A Withdrawn JP2018021936A (ja) | 2012-07-18 | 2017-11-08 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
| JP2019194447A Withdrawn JP2020012852A (ja) | 2012-07-18 | 2019-10-25 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
| JP2021172980A Pending JP2022009402A (ja) | 2012-07-18 | 2021-10-22 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017215430A Withdrawn JP2018021936A (ja) | 2012-07-18 | 2017-11-08 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
| JP2019194447A Withdrawn JP2020012852A (ja) | 2012-07-18 | 2019-10-25 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
| JP2021172980A Pending JP2022009402A (ja) | 2012-07-18 | 2021-10-22 | 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US9347867B2 (enExample) |
| EP (1) | EP2875351B1 (enExample) |
| JP (4) | JP6336697B2 (enExample) |
| KR (1) | KR20150036494A (enExample) |
| CN (2) | CN104641230B (enExample) |
| AU (1) | AU2013292378A1 (enExample) |
| BR (1) | BR112015001239A2 (enExample) |
| CA (1) | CA2878872A1 (enExample) |
| IL (1) | IL236767A (enExample) |
| IN (1) | IN2014DN11202A (enExample) |
| MX (1) | MX372784B (enExample) |
| SG (2) | SG10201605479QA (enExample) |
| WO (1) | WO2014015177A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101252259B1 (ko) * | 2011-12-12 | 2013-04-08 | 포항공과대학교 산학협력단 | 디스크형 미세 유체 시스템 및 혈액 상태 확인 방법 |
| SG10201605479QA (en) | 2012-07-18 | 2016-08-30 | Theranos Inc | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
| US8984932B2 (en) | 2012-07-18 | 2015-03-24 | Theranos, Inc. | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
| US20150241684A1 (en) | 2014-02-25 | 2015-08-27 | Theranos, Inc. | Systems, devices, and methods for sample integrity verification |
| US10591409B2 (en) | 2014-02-25 | 2020-03-17 | Theranos Ip Company, Llc | Systems, devices, and methods for sample integrity verification |
| JP6360696B2 (ja) * | 2014-03-18 | 2018-07-18 | 日本光電工業株式会社 | 血液検査装置および血液検査方法 |
| JP6681384B2 (ja) * | 2014-07-30 | 2020-04-15 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 粒子を処理するための自動化システム |
| CN104458519B (zh) * | 2014-12-08 | 2017-01-18 | 重庆南方数控设备有限责任公司 | 获取血沉数据的精确检测方法 |
| WO2016158139A1 (ja) * | 2015-03-31 | 2016-10-06 | ソニー株式会社 | 電気的特性測定装置、電気的特性測定方法、血液状態解析システム、及び該方法をコンピューターに実現させるための電気的特性測定用プログラム |
| JP6327751B2 (ja) * | 2015-10-06 | 2018-05-23 | 株式会社セルピック | 自動血液分離装置 |
| BR112018011639A2 (pt) * | 2015-12-08 | 2018-11-27 | Biomatrica Inc | redução de taxa de sedimentação de eritrócitos |
| WO2020170772A1 (ja) * | 2019-02-21 | 2020-08-27 | 株式会社シンキー | 遠心機において使用される検出器及び検出システム |
| SE545603C2 (en) * | 2019-08-22 | 2023-11-07 | Grimaldi Dev Ab | Separating particles through centrifugal sedimentation |
| CN111712703B (zh) * | 2019-11-18 | 2024-04-12 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析仪及样本分析方法 |
| CN112033868B (zh) * | 2020-09-01 | 2025-01-17 | 湖南伊鸿健康科技有限公司 | 一种加速细胞沉淀的方法、金属板及显微镜 |
| CN111912753A (zh) * | 2020-09-01 | 2020-11-10 | 湖南伊鸿健康科技有限公司 | 一种加速细胞沉淀的方法及装置 |
| CN112034192B (zh) * | 2020-09-07 | 2021-04-13 | 北京大学第三医院(北京大学第三临床医学院) | 一种血沉校正方法 |
| CN112766148A (zh) * | 2021-01-18 | 2021-05-07 | 河南大学 | 一种受人类扰动冲积地层沉积韵律的识别方法及系统 |
| TWI774220B (zh) * | 2021-01-29 | 2022-08-11 | 國泰醫療財團法人國泰綜合醫院 | 紅血球沈降速率量測方法、血液檢測載體與量測套組 |
| IT202100028064A1 (it) * | 2021-11-04 | 2023-05-04 | Arcangelo Ventura | Dispositivo per la misura automatica della velocita' di sedimentazione e del volume del fango. |
| CN119173763A (zh) * | 2022-05-10 | 2024-12-20 | 雷迪奥米特医学公司 | 基于全血样品中分析物的量的测量确定血浆中分析物的量 |
| KR102791324B1 (ko) * | 2023-03-22 | 2025-04-08 | 부산대학교 산학협력단 | 딥러닝을 이용한 적혈구 침강 속도 진단 시간 단축 방법 및 이를 위한 시스템 |
| WO2025144706A1 (en) * | 2023-12-28 | 2025-07-03 | Idexx Laboratories, Inc. | Determination of components in samples |
| CN119985470B (zh) * | 2025-01-14 | 2025-09-19 | 中国人民解放军总医院第八医学中心 | 基于图像检测的血液分离血浆样本的层析效果评估方法 |
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| US5914272A (en) * | 1996-06-19 | 1999-06-22 | Becton Dickinson And Company | Test method for determining the erythrocyte sedimentation rate and a surfactant for use therein |
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| JP5793567B2 (ja) | 2010-07-15 | 2015-10-14 | テルモ ビーシーティー、インコーポレーテッド | 生体液用の遠心分離装置において回転時間を最適化するための方法 |
| CN106290159A (zh) | 2011-01-21 | 2017-01-04 | 提拉诺斯公司 | 样品使用最大化的系统和方法 |
| US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
| US8984932B2 (en) | 2012-07-18 | 2015-03-24 | Theranos, Inc. | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
| SG10201605479QA (en) | 2012-07-18 | 2016-08-30 | Theranos Inc | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
-
2013
- 2013-07-18 SG SG10201605479QA patent/SG10201605479QA/en unknown
- 2013-07-18 KR KR1020157003471A patent/KR20150036494A/ko not_active Ceased
- 2013-07-18 JP JP2015523264A patent/JP6336697B2/ja not_active Expired - Fee Related
- 2013-07-18 SG SG11201500349YA patent/SG11201500349YA/en unknown
- 2013-07-18 MX MX2015000807A patent/MX372784B/es active IP Right Grant
- 2013-07-18 EP EP13820659.4A patent/EP2875351B1/en active Active
- 2013-07-18 BR BR112015001239A patent/BR112015001239A2/pt not_active Application Discontinuation
- 2013-07-18 CA CA2878872A patent/CA2878872A1/en not_active Abandoned
- 2013-07-18 AU AU2013292378A patent/AU2013292378A1/en not_active Abandoned
- 2013-07-18 IN IN11202DEN2014 patent/IN2014DN11202A/en unknown
- 2013-07-18 CN CN201380048272.2A patent/CN104641230B/zh active Active
- 2013-07-18 US US13/945,147 patent/US9347867B2/en active Active
- 2013-07-18 CN CN201910463083.0A patent/CN110187089B/zh active Active
- 2013-07-18 WO PCT/US2013/051143 patent/WO2014015177A1/en not_active Ceased
-
2015
- 2015-01-16 US US14/598,561 patent/US10222310B2/en active Active
- 2015-01-18 IL IL236767A patent/IL236767A/en active IP Right Grant
-
2016
- 2016-04-19 US US15/132,906 patent/US10018549B2/en active Active
-
2017
- 2017-11-08 JP JP2017215430A patent/JP2018021936A/ja not_active Withdrawn
-
2018
- 2018-06-06 US US16/001,760 patent/US10788409B2/en active Active
-
2019
- 2019-01-28 US US16/259,511 patent/US11320355B2/en active Active
- 2019-10-25 JP JP2019194447A patent/JP2020012852A/ja not_active Withdrawn
-
2020
- 2020-09-22 US US17/028,063 patent/US20210140866A1/en not_active Abandoned
-
2021
- 2021-10-22 JP JP2021172980A patent/JP2022009402A/ja active Pending
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