IN2014DN11202A - - Google Patents
Info
- Publication number
- IN2014DN11202A IN2014DN11202A IN11202DEN2014A IN2014DN11202A IN 2014DN11202 A IN2014DN11202 A IN 2014DN11202A IN 11202DEN2014 A IN11202DEN2014 A IN 11202DEN2014A IN 2014DN11202 A IN2014DN11202 A IN 2014DN11202A
- Authority
- IN
- India
- Prior art keywords
- sedimentation rate
- hematocrit
- sedimentation
- rate
- methods
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/10—Image acquisition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/011—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
- G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
- G01N2015/055—Investigating sedimentation of particle suspensions in blood for hematocrite determination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Multimedia (AREA)
- Theoretical Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261673037P | 2012-07-18 | 2012-07-18 | |
| PCT/US2013/051143 WO2014015177A1 (en) | 2012-07-18 | 2013-07-18 | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN11202A true IN2014DN11202A (en) | 2015-10-02 |
Family
ID=49945429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN11202DEN2014 IN2014DN11202A (en) | 2012-07-18 | 2013-07-18 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US9347867B2 (en) |
| EP (1) | EP2875351B1 (en) |
| JP (4) | JP6336697B2 (en) |
| KR (1) | KR20150036494A (en) |
| CN (2) | CN110187089B (en) |
| AU (1) | AU2013292378A1 (en) |
| BR (1) | BR112015001239A2 (en) |
| CA (1) | CA2878872A1 (en) |
| IL (1) | IL236767A (en) |
| IN (1) | IN2014DN11202A (en) |
| MX (1) | MX372784B (en) |
| SG (2) | SG10201605479QA (en) |
| WO (1) | WO2014015177A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101252259B1 (en) * | 2011-12-12 | 2013-04-08 | 포항공과대학교 산학협력단 | Microfluidic disc system and method for identifying state of blood |
| US8984932B2 (en) | 2012-07-18 | 2015-03-24 | Theranos, Inc. | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
| US9347867B2 (en) | 2012-07-18 | 2016-05-24 | Theranos, Inc. | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
| US10591409B2 (en) | 2014-02-25 | 2020-03-17 | Theranos Ip Company, Llc | Systems, devices, and methods for sample integrity verification |
| WO2015130828A1 (en) | 2014-02-25 | 2015-09-03 | Theranos, Inc. | Systems, devices, and methods for sample integrity verfication |
| JP6360696B2 (en) * | 2014-03-18 | 2018-07-18 | 日本光電工業株式会社 | Blood test apparatus and blood test method |
| CN106573256B (en) * | 2014-07-30 | 2019-06-14 | 豪夫迈·罗氏有限公司 | Automated systems for handling particles |
| CN104458519B (en) * | 2014-12-08 | 2017-01-18 | 重庆南方数控设备有限责任公司 | Precise detecting method for obtaining erythrocyte sedimentation data |
| EP3279649A4 (en) * | 2015-03-31 | 2018-12-26 | Sony Corporation | Electrical characteristic measurement device, electrical characteristic measurement method, blood condition analysis system, and electrical characteristic measurement program for computerizing said method |
| JP6327751B2 (en) * | 2015-10-06 | 2018-05-23 | 株式会社セルピック | Automatic blood separator |
| KR102787387B1 (en) * | 2015-12-08 | 2025-03-26 | 바이오매트리카 인코포레이티드 | Reduction of erythrocyte sedimentation rate |
| JP6858947B2 (en) * | 2019-02-21 | 2021-04-14 | 株式会社シンキー | Detectors and detection systems used in centrifuges |
| SE545603C2 (en) * | 2019-08-22 | 2023-11-07 | Grimaldi Dev Ab | Separating particles through centrifugal sedimentation |
| WO2021097610A1 (en) * | 2019-11-18 | 2021-05-27 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analyzer and sample analysis method |
| CN112033868B (en) * | 2020-09-01 | 2025-01-17 | 湖南伊鸿健康科技有限公司 | Method for accelerating cell precipitation, metal plate and microscope |
| CN111912753A (en) * | 2020-09-01 | 2020-11-10 | 湖南伊鸿健康科技有限公司 | Method and device for accelerating cell precipitation |
| CN112034192B (en) * | 2020-09-07 | 2021-04-13 | 北京大学第三医院(北京大学第三临床医学院) | A kind of erythrocyte sedimentation rate correction method |
| CN112766148A (en) * | 2021-01-18 | 2021-05-07 | 河南大学 | Method and system for identifying stratum deposition rhythm disturbed and alluvial by human |
| TWI774220B (en) * | 2021-01-29 | 2022-08-11 | 國泰醫療財團法人國泰綜合醫院 | Erythrocyte sedimentation rate measurement method, blood detection carrier and measurement kit |
| IT202100028064A1 (en) * | 2021-11-04 | 2023-05-04 | Arcangelo Ventura | DEVICE FOR THE AUTOMATIC MEASUREMENT OF THE SEDIMENTATION SPEED AND VOLUME OF THE SLUDGE. |
| EP4522985A1 (en) * | 2022-05-10 | 2025-03-19 | Radiometer Medical ApS | Determining an amount of analyte in plasma based on a measurement of an amount of analyte in a whole-blood sample |
| KR102791324B1 (en) * | 2023-03-22 | 2025-04-08 | 부산대학교 산학협력단 | Method for shortening the measurement time of erythrocyte sedimentation rate using deep learning and system therefor |
| US20250216388A1 (en) * | 2023-12-28 | 2025-07-03 | Idexx Laboratories, Inc. | Determination of Components in Samples |
| CN119985470B (en) * | 2025-01-14 | 2025-09-19 | 中国人民解放军总医院第八医学中心 | Image detection-based method for evaluating the chromatographic effect of blood-separated plasma samples |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| NL92884C (en) * | 1953-07-09 | |||
| US3288019A (en) * | 1962-05-08 | 1966-11-29 | Charles M Blumenfeld | Photographic type sedimentation recorder |
| US3848796A (en) * | 1971-02-08 | 1974-11-19 | Coulter Electronics | A centrifuge apparatus for sedimentation study |
| US4010893A (en) | 1975-06-20 | 1977-03-08 | Becton, Dickinson And Company | Triac centrifuge |
| US4197735A (en) | 1978-11-06 | 1980-04-15 | Chase Instruments Corporation | Blood sedimentation rate test means |
| US4558947A (en) | 1983-11-07 | 1985-12-17 | Wardlaw Stephen C | Method and apparatus for measuring blood constituent counts |
| US4745279A (en) | 1986-01-02 | 1988-05-17 | American Hospital Supply Corporation | Hematocrit measuring apparatus |
| US4848900A (en) | 1987-06-22 | 1989-07-18 | Kuo Cheng Deng | Computerized automatic monitoring and recording system of erythrocyte sedimentation process |
| JPH0275959A (en) * | 1988-09-12 | 1990-03-15 | Nittec Co Ltd | Automatic analysis apparatus |
| US5003488A (en) * | 1989-03-10 | 1991-03-26 | Gespac, Inc. | Automatic fluid sedimentation rate measurement apparatus and method |
| CA2011100C (en) | 1989-05-24 | 1996-06-11 | Stephen C. Wardlaw | Centrifuged material layer measurements taken in an evacuated tube |
| US5578269A (en) | 1993-06-11 | 1996-11-26 | Ortho Diagnostic Systems Inc. | Automated blood analysis system with an integral centrifuge |
| US5594164A (en) * | 1994-07-12 | 1997-01-14 | Bull; Brian S. | Method and apparatus for rapid determination of blood sedimentation rate |
| US6506606B1 (en) | 1995-06-06 | 2003-01-14 | Brigham And Women's Hospital | Method and apparatus for determining erythrocyte sedimentation rate and hematocrit |
| CN2259629Y (en) * | 1995-12-26 | 1997-08-13 | 张崇俊 | Micro blood volume sedimentometer |
| US5914272A (en) * | 1996-06-19 | 1999-06-22 | Becton Dickinson And Company | Test method for determining the erythrocyte sedimentation rate and a surfactant for use therein |
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| US20010044584A1 (en) | 1997-08-28 | 2001-11-22 | Kensey Kenneth R. | In vivo delivery methods and compositions |
| GB9804560D0 (en) | 1998-03-05 | 1998-04-29 | Zynocyte Ltd | Method of measuring erthrocyte sedimentation rate (esr),plasma viscosity and plasma fibrinogen of a blood sample |
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| WO2011049886A1 (en) | 2009-10-19 | 2011-04-28 | Theranos, Inc. | Integrated health data capture and analysis system |
| US20110226045A1 (en) | 2009-11-25 | 2011-09-22 | Mcquillan Adrian Charles | Liquid analysis system |
| CN201773058U (en) * | 2010-01-08 | 2011-03-23 | 郭瑞林 | Blood sedimentation tube with negative-pressure air bag |
| US20110295365A1 (en) * | 2010-05-28 | 2011-12-01 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-viral compositions and methods for administration |
| JP5793567B2 (en) | 2010-07-15 | 2015-10-14 | テルモ ビーシーティー、インコーポレーテッド | Method for optimizing rotation time in a centrifuge for biological fluids |
| AR085087A1 (en) | 2011-01-21 | 2013-09-11 | Theranos Inc | SYSTEMS AND METHODS TO MAXIMIZE THE USE OF SAMPLES |
| US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
| US8984932B2 (en) | 2012-07-18 | 2015-03-24 | Theranos, Inc. | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
| US9347867B2 (en) | 2012-07-18 | 2016-05-24 | Theranos, Inc. | Rapid measurement of formed blood component sedimentation rate from small sample volumes |
-
2013
- 2013-07-18 US US13/945,147 patent/US9347867B2/en active Active
- 2013-07-18 CN CN201910463083.0A patent/CN110187089B/en active Active
- 2013-07-18 BR BR112015001239A patent/BR112015001239A2/en not_active Application Discontinuation
- 2013-07-18 EP EP13820659.4A patent/EP2875351B1/en active Active
- 2013-07-18 SG SG10201605479QA patent/SG10201605479QA/en unknown
- 2013-07-18 KR KR1020157003471A patent/KR20150036494A/en not_active Ceased
- 2013-07-18 AU AU2013292378A patent/AU2013292378A1/en not_active Abandoned
- 2013-07-18 MX MX2015000807A patent/MX372784B/en active IP Right Grant
- 2013-07-18 WO PCT/US2013/051143 patent/WO2014015177A1/en not_active Ceased
- 2013-07-18 CA CA2878872A patent/CA2878872A1/en not_active Abandoned
- 2013-07-18 SG SG11201500349YA patent/SG11201500349YA/en unknown
- 2013-07-18 IN IN11202DEN2014 patent/IN2014DN11202A/en unknown
- 2013-07-18 JP JP2015523264A patent/JP6336697B2/en not_active Expired - Fee Related
- 2013-07-18 CN CN201380048272.2A patent/CN104641230B/en active Active
-
2015
- 2015-01-16 US US14/598,561 patent/US10222310B2/en active Active
- 2015-01-18 IL IL236767A patent/IL236767A/en active IP Right Grant
-
2016
- 2016-04-19 US US15/132,906 patent/US10018549B2/en active Active
-
2017
- 2017-11-08 JP JP2017215430A patent/JP2018021936A/en not_active Withdrawn
-
2018
- 2018-06-06 US US16/001,760 patent/US10788409B2/en active Active
-
2019
- 2019-01-28 US US16/259,511 patent/US11320355B2/en active Active
- 2019-10-25 JP JP2019194447A patent/JP2020012852A/en not_active Withdrawn
-
2020
- 2020-09-22 US US17/028,063 patent/US20210140866A1/en not_active Abandoned
-
2021
- 2021-10-22 JP JP2021172980A patent/JP2022009402A/en active Pending
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