IN2014DN11202A - - Google Patents

Info

Publication number
IN2014DN11202A
IN2014DN11202A IN11202DEN2014A IN2014DN11202A IN 2014DN11202 A IN2014DN11202 A IN 2014DN11202A IN 11202DEN2014 A IN11202DEN2014 A IN 11202DEN2014A IN 2014DN11202 A IN2014DN11202 A IN 2014DN11202A
Authority
IN
India
Prior art keywords
sedimentation rate
hematocrit
sedimentation
rate
methods
Prior art date
Application number
Inventor
Mark Dayel
Samartha Anekal
Elizabeth A Holmes
Original Assignee
Theranos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theranos Inc filed Critical Theranos Inc
Publication of IN2014DN11202A publication Critical patent/IN2014DN11202A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/042Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30Control equipment
    • B01D21/32Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/10Image acquisition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/011Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/042Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • G01N2015/055Investigating sedimentation of particle suspensions in blood for hematocrite determination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Multimedia (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
IN11202DEN2014 2012-07-18 2013-07-18 IN2014DN11202A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261673037P 2012-07-18 2012-07-18
PCT/US2013/051143 WO2014015177A1 (en) 2012-07-18 2013-07-18 Rapid measurement of formed blood component sedimentation rate from small sample volumes

Publications (1)

Publication Number Publication Date
IN2014DN11202A true IN2014DN11202A (en) 2015-10-02

Family

ID=49945429

Family Applications (1)

Application Number Title Priority Date Filing Date
IN11202DEN2014 IN2014DN11202A (en) 2012-07-18 2013-07-18

Country Status (13)

Country Link
US (6) US9347867B2 (en)
EP (1) EP2875351B1 (en)
JP (4) JP6336697B2 (en)
KR (1) KR20150036494A (en)
CN (2) CN110187089B (en)
AU (1) AU2013292378A1 (en)
BR (1) BR112015001239A2 (en)
CA (1) CA2878872A1 (en)
IL (1) IL236767A (en)
IN (1) IN2014DN11202A (en)
MX (1) MX372784B (en)
SG (2) SG10201605479QA (en)
WO (1) WO2014015177A1 (en)

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IT202100028064A1 (en) * 2021-11-04 2023-05-04 Arcangelo Ventura DEVICE FOR THE AUTOMATIC MEASUREMENT OF THE SEDIMENTATION SPEED AND VOLUME OF THE SLUDGE.
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Also Published As

Publication number Publication date
MX372784B (en) 2020-07-01
US20140020457A1 (en) 2014-01-23
SG11201500349YA (en) 2015-02-27
CN110187089A (en) 2019-08-30
JP2022009402A (en) 2022-01-14
JP2015528910A (en) 2015-10-01
CN110187089B (en) 2021-10-29
US20210140866A1 (en) 2021-05-13
CN104641230A (en) 2015-05-20
EP2875351B1 (en) 2022-11-09
CA2878872A1 (en) 2014-01-23
US20150198515A1 (en) 2015-07-16
KR20150036494A (en) 2015-04-07
EP2875351A4 (en) 2016-06-15
JP2018021936A (en) 2018-02-08
SG10201605479QA (en) 2016-08-30
US10222310B2 (en) 2019-03-05
US11320355B2 (en) 2022-05-03
JP2020012852A (en) 2020-01-23
IL236767A (en) 2017-06-29
WO2014015177A1 (en) 2014-01-23
US10018549B2 (en) 2018-07-10
US20190170630A1 (en) 2019-06-06
AU2013292378A1 (en) 2015-01-29
CN104641230B (en) 2019-06-28
JP6336697B2 (en) 2018-06-06
MX2015000807A (en) 2015-05-07
US20160341650A1 (en) 2016-11-24
HK1210833A1 (en) 2016-05-06
US20190226967A1 (en) 2019-07-25
US10788409B2 (en) 2020-09-29
EP2875351A1 (en) 2015-05-27
BR112015001239A2 (en) 2017-07-04
US9347867B2 (en) 2016-05-24

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