JP6336067B2 - 関節症の場合のペプスタチンの関節内適応 - Google Patents
関節症の場合のペプスタチンの関節内適応 Download PDFInfo
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- JP6336067B2 JP6336067B2 JP2016532244A JP2016532244A JP6336067B2 JP 6336067 B2 JP6336067 B2 JP 6336067B2 JP 2016532244 A JP2016532244 A JP 2016532244A JP 2016532244 A JP2016532244 A JP 2016532244A JP 6336067 B2 JP6336067 B2 JP 6336067B2
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- pepstatin
- intra
- arthropathy
- cathepsin
- treatment
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| EP13003923 | 2013-08-06 | ||
| EP13003923.3 | 2013-08-06 | ||
| PCT/EP2014/001861 WO2015018472A1 (de) | 2013-08-06 | 2014-07-07 | Intraartikuläre applikation von pepstatin bei arthrose |
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| JP2016527284A JP2016527284A (ja) | 2016-09-08 |
| JP2016527284A5 JP2016527284A5 (https=) | 2017-08-17 |
| JP6336067B2 true JP6336067B2 (ja) | 2018-06-06 |
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| JP (1) | JP6336067B2 (https=) |
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| CA (1) | CA2920420C (https=) |
| ES (1) | ES2759060T3 (https=) |
| IL (1) | IL243983B (https=) |
| WO (1) | WO2015018472A1 (https=) |
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| CA2280096A1 (en) | 1997-02-04 | 1998-08-06 | The Regents Of The University Of California | Nanomolar, non-peptide inhibitors of cathepsin d |
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| US20080132477A1 (en) | 2005-01-13 | 2008-06-05 | Claudia Betschart | Macrocyclic Compounds Useful as Bace Inhibitors |
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| EP1867329A3 (en) | 2006-06-14 | 2008-05-07 | Speedel Experimenta AG | 5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamides as therapeutic compounds |
| EP1987834A3 (en) | 2007-02-13 | 2008-11-19 | Speedel Experimenta AG | Substituted piperidines as therapeutic compounds |
| WO2008119772A1 (en) | 2007-03-30 | 2008-10-09 | Medivir Ab | Amide derivatives as inhibitors of aspartyl proteases |
| WO2009013293A1 (en) | 2007-07-24 | 2009-01-29 | Novartis Ag | Substituted cyclohexanecarboxamides useful as bace inhibitors |
| MX2013009064A (es) * | 2011-02-08 | 2013-10-01 | Merck Patent Gmbh | Derivados de aminostatina para el tratamiento de artrosis. |
| US20150225369A1 (en) * | 2012-08-29 | 2015-08-13 | Merck Patent Gmbh | Ddr2 inhibitors for the treatment of osteoarthritis |
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2014
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- 2014-07-07 US US14/910,317 patent/US9750784B2/en not_active Expired - Fee Related
- 2014-07-07 AU AU2014304950A patent/AU2014304950B2/en not_active Ceased
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- 2014-07-07 EP EP14741803.2A patent/EP3030250B1/de active Active
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|---|---|
| EP3030250B1 (de) | 2019-08-28 |
| AU2014304950A1 (en) | 2016-03-17 |
| US20170348380A1 (en) | 2017-12-07 |
| WO2015018472A1 (de) | 2015-02-12 |
| JP2016527284A (ja) | 2016-09-08 |
| AU2014304950B2 (en) | 2019-09-12 |
| EP3030250A1 (de) | 2016-06-15 |
| IL243983B (en) | 2020-04-30 |
| IL243983A0 (en) | 2016-04-21 |
| US20160175381A1 (en) | 2016-06-23 |
| US9750784B2 (en) | 2017-09-05 |
| ES2759060T3 (es) | 2020-05-07 |
| CA2920420C (en) | 2021-11-23 |
| CN105451754A (zh) | 2016-03-30 |
| CA2920420A1 (en) | 2015-02-12 |
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