JP6329367B2 - 組織学的なサンプルを処理するための処理装置、保持デバイス、処理方法 - Google Patents

組織学的なサンプルを処理するための処理装置、保持デバイス、処理方法 Download PDF

Info

Publication number
JP6329367B2
JP6329367B2 JP2013268375A JP2013268375A JP6329367B2 JP 6329367 B2 JP6329367 B2 JP 6329367B2 JP 2013268375 A JP2013268375 A JP 2013268375A JP 2013268375 A JP2013268375 A JP 2013268375A JP 6329367 B2 JP6329367 B2 JP 6329367B2
Authority
JP
Japan
Prior art keywords
processing
sample
station
processing apparatus
embedding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2013268375A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014130146A5 (enExample
JP2014130146A (ja
Inventor
エッケルト ラルフ
エッケルト ラルフ
ベリベリッヒ マルクス
ベリベリッヒ マルクス
ウルプリッヒ ヘルマン
ウルプリッヒ ヘルマン
Original Assignee
ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー
ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE202012105095U external-priority patent/DE202012105095U1/de
Priority claimed from DE201310204645 external-priority patent/DE102013204645B3/de
Application filed by ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー, ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー filed Critical ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー
Publication of JP2014130146A publication Critical patent/JP2014130146A/ja
Publication of JP2014130146A5 publication Critical patent/JP2014130146A5/ja
Application granted granted Critical
Publication of JP6329367B2 publication Critical patent/JP6329367B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N2001/315—Basket-type carriers for tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Robotics (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2013268375A 2012-12-28 2013-12-26 組織学的なサンプルを処理するための処理装置、保持デバイス、処理方法 Expired - Fee Related JP6329367B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE202012105095U DE202012105095U1 (de) 2012-12-28 2012-12-28 Fixierbehälter zum Aufnehmen einer histologischen Probe
DE202012105095.1 2012-12-28
DE201310204645 DE102013204645B3 (de) 2013-03-15 2013-03-15 Prozessor zum Bearbeiten von histologischen Proben
DE102013204645.6 2013-03-15

Publications (3)

Publication Number Publication Date
JP2014130146A JP2014130146A (ja) 2014-07-10
JP2014130146A5 JP2014130146A5 (enExample) 2017-01-12
JP6329367B2 true JP6329367B2 (ja) 2018-05-23

Family

ID=51017599

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013268375A Expired - Fee Related JP6329367B2 (ja) 2012-12-28 2013-12-26 組織学的なサンプルを処理するための処理装置、保持デバイス、処理方法

Country Status (4)

Country Link
US (1) US9568402B2 (enExample)
JP (1) JP6329367B2 (enExample)
CN (1) CN103913366B (enExample)
GB (1) GB2510466B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015114893A1 (de) * 2015-09-04 2017-03-09 Leica Biosystems Nussloch Gmbh Verfahren und Automat zum Einbetten einer Gewebeprobe in ein Einbettmedium
JP6746470B2 (ja) * 2016-11-08 2020-08-26 日本電子株式会社 カートリッジ保持装置
US20210072123A1 (en) 2018-05-07 2021-03-11 Eleonora Iljinichna Tjan Device for Processing and Infiltrating Histological and Biological Samples
KR102974177B1 (ko) * 2018-12-20 2026-06-10 라이카 바이오시스템즈 멜버른 피티와이 엘티디 슬라이드 트레이 어셈블리

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08500434A (ja) * 1992-05-13 1996-01-16 オーストラリアン バイオメディカル コーポレーション リミテッド スライド標本用自動染色装置
US5817032A (en) * 1996-05-14 1998-10-06 Biopath Automation Llc. Means and method for harvesting and handling tissue samples for biopsy analysis
DE19647662C1 (de) 1996-11-19 1998-03-12 Leica Instr Gmbh Antriebseinrichtung für einen Einbettautomaten zur Behandlung von Proben für histologische Untersuchungen
US20010055799A1 (en) * 1998-12-15 2001-12-27 David Baunoch Method and apparatus for automated reprocessing of tissue samples
DE10052832A1 (de) 2000-10-24 2002-04-25 Leica Microsystems Vorrichtung zur Behandlung von Objekten
CN100439894C (zh) * 2002-09-26 2008-12-03 比欧帕斯自动化公司 用于自动处理和包埋组织标本的设备和方法
US7208559B2 (en) 2002-12-27 2007-04-24 Mitsui Chemicals, Inc. Ethylened polymer and molded object obtained therefrom
US7648678B2 (en) * 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
JP5308156B2 (ja) * 2005-09-06 2013-10-09 レイカ バイオシステムズ メルボルン ピーティーワイ リミテッド 組織標本の処理方法及び処理装置
DE102005057201B4 (de) 2005-11-29 2012-11-08 Leica Instruments (Singapore) Pte. Ltd. Gewebeprozessor
US7875242B2 (en) * 2006-10-17 2011-01-25 Preyas Sarabhai Shah Slide stainer with multiple heater stations
DE102007008713B4 (de) * 2007-02-20 2019-07-11 Leica Biosystems Nussloch Gmbh Gewebeinfiltrationsvorrichtung
DE202007013921U1 (de) * 2007-09-16 2007-12-27 Leica Biosystems Nussloch Gmbh Gewebeinfiltrationsvorrichtung
JP5705727B2 (ja) * 2008-06-18 2015-04-22 ライカ・バイオシステムズ・メルボルン・プロプライエタリー・リミテッドＬｅｉｃａ Ｂｉｏｓｙｓｔｅｍｓ Ｍｅｌｂｏｕｒｎｅ Ｐｔｙ Ｌｔｄ 組織の取扱いおよび包埋のための装置ならびに方法における改良のためのサンプルキャリア支持体
DE102008039861A1 (de) 2008-08-27 2010-03-04 Leica Biosystems Nussloch Gmbh Gewebeprozessor
DE102008039875B4 (de) 2008-08-27 2014-08-14 Leica Instruments (Singapore) Pte. Ltd. Verfahren und Vorrichtung zum Infiltrieren von Gewebeproben mit Paraffin
DE102008050525A1 (de) * 2008-10-06 2010-04-22 Leica Biosystems Nussloch Gmbh Vorrichtung und Verfahren zur Kennzeichnung mindestens eines Objektträgers
DE102008056584B4 (de) 2008-11-10 2012-01-19 Leica Biosystems Nussloch Gmbh Verfahren und Vorrichtung zur Behandlung von Objekten
DE102008054066B4 (de) 2008-10-31 2015-03-19 Leica Biosystems Nussloch Gmbh Verfahren zum Bearbeiten von Gewebeproben unter Verwendung eines Sensors
DE102008054071B4 (de) 2008-10-31 2014-02-20 Leica Biosystems Nussloch Gmbh Verfahren zum Betreiben eines Gewebeprozessors und Gewebeprozessor
BRPI0923630A2 (pt) * 2008-12-30 2016-01-19 Biopath Automation Llc sistemas e métodos de processamento e incorporação de amostras de tecido para biópsia durante processo de histopalogia e de realização de pelo menos parte do mesmo.
DE102009015596A1 (de) 2009-03-30 2010-10-21 Dcs Innovative Diagnostik-Systeme Dr. Christian Sartori Gmbh & Co. Kg Verfahren und Vorrichtung zur Behandlung von trägerfixiertem Material
DE102009025574A1 (de) 2009-06-19 2010-12-23 Leica Biosystems Nussloch Gmbh Verfahren zum automatischen Bearbeiten von Gewebeproben in einem Gewebeprozessor
DE102009038481B4 (de) 2009-08-21 2011-09-01 Leica Biosystems Nussloch Gmbh Verfahren zum Betreiben eines Gewebeprozessors
DE112010004388B4 (de) 2009-11-13 2019-03-14 Leica Biosystems Nussloch Gmbh Anzeige eines systemzustands einer behandlungseinrichtung für mikroskopische proben
JP5331056B2 (ja) * 2010-05-19 2013-10-30 株式会社日立ハイテクノロジーズ 自動分析装置
DE102011003369B4 (de) * 2011-01-31 2019-06-27 Leica Biosystems Nussloch Gmbh Bearbeitungsautomat zur Bearbeitung von auf Objektträgern aufgebrachten Proben aufweisend eine Ausgabeeinrichtung
DE102011003366B4 (de) 2011-01-31 2019-07-11 Leica Biosystems Nussloch Gmbh Bearbeitungsautomat zur Bearbeitung von auf Objektträgern aufgebrachten Proben aufweisend eine Beschickungseinrichtung
CN202339295U (zh) * 2011-11-10 2012-07-18 罗东华 生物组织处理一体机
DE202013103590U1 (de) 2013-03-15 2014-06-16 Leica Biosystems Nussloch Gmbh Prozessor zum Bearbeiten von histologischen Proben
DE202012105095U1 (de) 2012-12-28 2013-01-21 Leica Biosystems Nussloch Gmbh Fixierbehälter zum Aufnehmen einer histologischen Probe

Also Published As

Publication number Publication date
CN103913366A (zh) 2014-07-09
GB2510466A (en) 2014-08-06
CN103913366B (zh) 2019-03-08
GB2510466B (en) 2015-05-06
US9568402B2 (en) 2017-02-14
GB201321225D0 (en) 2014-01-15
JP2014130146A (ja) 2014-07-10
US20140186883A1 (en) 2014-07-03

Similar Documents

Publication Publication Date Title
US9194776B2 (en) Processor for working on histological samples
JP5894142B2 (ja) 複数の細胞懸濁物を調製及び解析する自動プロセス及び自動化デバイス
JP5705727B2 (ja) 組織の取扱いおよび包埋のための装置ならびに方法における改良のためのサンプルキャリア支持体
US5424040A (en) Tissue specimen collection kit
JP2014130146A (ja) 組織学的なサンプルを処理するための処理装置、保持デバイス、処理方法
WO2006060317A1 (en) Apparatus and method for histological processing of a tissue specimen with means for maintaining the orientation of the specimen throughout the processing
JPWO2011040203A1 (ja) 検体処理自動化システム
CN110608934B (zh) 一种独立脱水包埋组件及其使用方法
CN108841713A (zh) 理化处理单个细胞的微流控芯片、微流控装置及使用其理化处理单个细胞的方法
US20140186882A1 (en) Method for fixing a histological sample
GB2489920A (en) Apparatus and method for automatically preparing pre-analysis cytological specimens
US9664701B2 (en) System for handling slides having two coverslipper modules
JP2014130146A5 (enExample)
US9482601B2 (en) Portable device for transporting a histological sample
EP3955007A1 (en) Transport mechanism and analyzing device
CN102918398B (zh) 分析装置及分析方法
CN217359218U (zh) 液基制片设备
CN113866436A (zh) 一种细胞分析系统
KR20190012677A (ko) 시료채취장치 및 이를 이용한 시료채취방법
EP3642632A1 (en) Method of handling at least one pathologic specimen
CN223827399U (zh) 一种用于皮肤病理实验的工具套件
CN105142532A (zh) 用于固体生物样品的分析的样品支架
JP2006122066A5 (enExample)
DE102013216431A1 (de) Prozessor zum Bearbeiten von histologischen Proben

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161125

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20161125

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20170824

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170912

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171026

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180327

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180420

R150 Certificate of patent or registration of utility model

Ref document number: 6329367

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees