JP6316941B2 - 神経機能状態の監視 - Google Patents

神経機能状態の監視 Download PDF

Info

Publication number
JP6316941B2
JP6316941B2 JP2016512037A JP2016512037A JP6316941B2 JP 6316941 B2 JP6316941 B2 JP 6316941B2 JP 2016512037 A JP2016512037 A JP 2016512037A JP 2016512037 A JP2016512037 A JP 2016512037A JP 6316941 B2 JP6316941 B2 JP 6316941B2
Authority
JP
Japan
Prior art keywords
blink
subject
reflection
eye
reflex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016512037A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016520381A5 (cg-RX-API-DMAC10.html
JP2016520381A (ja
Inventor
トレヴァニアン ツァイ,ナンシー
トレヴァニアン ツァイ,ナンシー
エーヴァルド セムラー,マーク
エーヴァルド セムラー,マーク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MUSC Foundation for Research and Development
Original Assignee
MUSC Foundation for Research and Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MUSC Foundation for Research and Development filed Critical MUSC Foundation for Research and Development
Publication of JP2016520381A publication Critical patent/JP2016520381A/ja
Publication of JP2016520381A5 publication Critical patent/JP2016520381A5/ja
Application granted granted Critical
Publication of JP6316941B2 publication Critical patent/JP6316941B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0016—Operational features thereof
    • A61B3/0025—Operational features thereof characterised by electronic signal processing, e.g. eye models
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0016—Operational features thereof
    • A61B3/0033—Operational features thereof characterised by user input arrangements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0016—Operational features thereof
    • A61B3/0041—Operational features thereof characterised by display arrangements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/11—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils
    • A61B3/112—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils for measuring diameter of pupils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/113—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining or recording eye movement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/145—Arrangements specially adapted for eye photography by video means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • A61B5/1103—Detecting muscular movement of the eye, e.g. eyelid movement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/163—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state by tracking eye movement, gaze, or pupil change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/398—Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0013—Medical image data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/162—Testing reaction times
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4863—Measuring or inducing nystagmus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Human Computer Interaction (AREA)
  • Signal Processing (AREA)
  • Multimedia (AREA)
  • Hospice & Palliative Care (AREA)
  • Developmental Disabilities (AREA)
  • Educational Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • User Interface Of Digital Computer (AREA)
JP2016512037A 2013-05-01 2014-05-01 神経機能状態の監視 Active JP6316941B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361818087P 2013-05-01 2013-05-01
US61/818,087 2013-05-01
PCT/US2014/036349 WO2014179558A1 (en) 2013-05-01 2014-05-01 Monitoring neurological functional status

Publications (3)

Publication Number Publication Date
JP2016520381A JP2016520381A (ja) 2016-07-14
JP2016520381A5 JP2016520381A5 (cg-RX-API-DMAC10.html) 2017-06-15
JP6316941B2 true JP6316941B2 (ja) 2018-04-25

Family

ID=51843947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016512037A Active JP6316941B2 (ja) 2013-05-01 2014-05-01 神経機能状態の監視

Country Status (7)

Country Link
US (3) US10448825B2 (cg-RX-API-DMAC10.html)
EP (1) EP2991542B1 (cg-RX-API-DMAC10.html)
JP (1) JP6316941B2 (cg-RX-API-DMAC10.html)
AU (1) AU2014259786B2 (cg-RX-API-DMAC10.html)
BR (1) BR112015027598A2 (cg-RX-API-DMAC10.html)
CA (1) CA2909785C (cg-RX-API-DMAC10.html)
WO (1) WO2014179558A1 (cg-RX-API-DMAC10.html)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6316941B2 (ja) 2013-05-01 2018-04-25 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント 神経機能状態の監視
JP6535223B2 (ja) * 2015-05-28 2019-06-26 浜松ホトニクス株式会社 瞬目計測方法、瞬目計測装置、及び瞬目計測プログラム
TWI616188B (zh) * 2015-06-04 2018-03-01 神經元科技股份有限公司 腦疾病快速篩檢裝置
EP3302249A4 (en) * 2015-06-04 2019-01-16 The Research Foundation for The State University of New York Diagnosis of mild traumatic brain injury
WO2017216799A1 (en) * 2016-06-16 2017-12-21 Hadasit Medical Research Services And Development Ltd. Ablation catheter tips and catheters
US10925479B2 (en) * 2016-10-13 2021-02-23 Ronald Michael Kurtz Networked system of mobile communication platforms for nonpharmacologic constriction of a pupil
JP6852407B2 (ja) * 2017-01-17 2021-03-31 トヨタ自動車株式会社 ドライバ状態検出装置
US11141095B2 (en) * 2017-02-17 2021-10-12 Oculogica Inc. Method and system for detecting concussion
US10198068B2 (en) * 2017-02-28 2019-02-05 Microsoft Technology Licensing, Llc Blink detection, tracking, and stimulation
JP6749278B2 (ja) * 2017-04-14 2020-09-02 ダイキン工業株式会社 生理状態判定装置
SG10201703570YA (en) 2017-05-02 2018-12-28 Singapore Health Serv Pte Ltd Hand held ophthalmic and neurological screening device
US20200069239A1 (en) * 2017-05-15 2020-03-05 Musc Foundation For Research Development Device, system and method for monitoring neurological functional status
US12672823B2 (en) 2018-05-22 2026-07-07 Lifelens Technologies, Inc. Monitoring physiologic parameters for timing feedback to enhance performance of a subject during an activity
US20210290149A1 (en) * 2018-07-05 2021-09-23 Highmark Innovations Inc. System for generating indications of neurological impairment
US20210386345A1 (en) 2018-10-23 2021-12-16 Sdip Holdings Pty Ltd Devices and processing systems configured to enable extended monitoring and analysis of subject neurological factors via blepharometric data collection
EP3981324B1 (en) * 2019-06-07 2025-01-08 Daikin Industries, Ltd. Assessment system
JP2023524884A (ja) * 2020-05-14 2023-06-13 ヴューポイントシステム ゲー・エム・ベー・ハー 眼鏡および瞳孔中心を決定する方法
JPWO2022003929A1 (cg-RX-API-DMAC10.html) * 2020-07-03 2022-01-06
JP7874885B2 (ja) * 2020-11-10 2026-06-17 ザ、トラスティーズ オブ プリンストン ユニバーシティ 遠隔神経行動試験のためのシステム及び方法
US12264971B2 (en) 2021-03-09 2025-04-01 Welch Allyn, Inc. Noncontact thermometer
US12518388B2 (en) 2021-05-28 2026-01-06 Blinktbi, Inc. Systems and methods for eyelid localization
EP4387513A4 (en) 2021-08-17 2024-12-18 Hadasit Medical Research Services And Development Limited METHODS, SYSTEMS AND DEVICES FOR DETERMINING A STATE OF BRAIN AND/OR NERVOUS FUNCTIONS OF A PATIENT
WO2023172561A1 (en) * 2022-03-07 2023-09-14 Blinktbi, Inc. Use of blink reflex for parkinson's disease response monitoring and/or treatment selection
CN114767054A (zh) * 2022-04-15 2022-07-22 灵动翘睫(深圳)科技有限公司 一种基于激光导航的用于眨眼反射测量的气体喷射控制方法
AU2024259510A1 (en) * 2023-04-19 2025-10-23 Blinklab Method and system for measuring brain reflexes and the modulatory effect of engagement and lifestyle
WO2025048824A1 (en) * 2023-08-31 2025-03-06 Magic Leap, Inc. User heart rate detection system and method using fusion of multi-sensor data
WO2025149652A1 (en) * 2024-01-10 2025-07-17 Mgme Neurotech Gmbh Methods and systems for determining a physiological response of the eye of a user
WO2026039460A1 (en) 2024-08-13 2026-02-19 Blinktbi, Inc. Systems and methods for determining degree of eye closure

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62275432A (ja) 1986-05-22 1987-11-30 オリンパス光学工業株式会社 眼科用検査装置
US4850691A (en) 1987-03-18 1989-07-25 University Of Illinois Method and apparatus for determining pupillary response parameters
US4815839A (en) * 1987-08-03 1989-03-28 Waldorf Ronald A Infrared/video electronystagmographic apparatus
JPH04279143A (ja) * 1990-12-29 1992-10-05 Koonan:Kk 眼球運動検査装置
JPH04126505U (ja) 1991-05-07 1992-11-18 オムロン株式会社 センサ一体型光刺激装置
US5137345A (en) * 1991-05-15 1992-08-11 Oculokinetics, Inc. Apparatus for monitoring physiolgical data to detect drug impairment
US5333009A (en) 1993-08-05 1994-07-26 Gell Jr Harold A Method and apparatus for inducing reflex blink reactions
JP3348956B2 (ja) * 1994-03-24 2002-11-20 ソニー株式会社 表示装置
US5570698A (en) 1995-06-02 1996-11-05 Siemens Corporate Research, Inc. System for monitoring eyes for detecting sleep behavior
JP3183161B2 (ja) 1996-04-12 2001-07-03 三菱自動車工業株式会社 覚醒度推定装置
US6542081B2 (en) 1996-08-19 2003-04-01 William C. Torch System and method for monitoring eye movement
US5867587A (en) 1997-05-19 1999-02-02 Northrop Grumman Corporation Impaired operator detection and warning system employing eyeblink analysis
FR2773521B1 (fr) 1998-01-15 2000-03-31 Carlus Magnus Limited Procede et dispositif pour surveiller en continu l'etat de vigilance du conducteur d'un vehicule automobile, afin de detecter et prevenir une tendance eventuelle a l'endormissement de celui-ci
US6091334A (en) 1998-09-04 2000-07-18 Massachusetts Institute Of Technology Drowsiness/alertness monitor
DE19983911B4 (de) 1999-01-27 2018-09-06 Compumedics Sleep Pty. Ltd. Wachsamkeitsüberwachungssystem
US6820979B1 (en) 1999-04-23 2004-11-23 Neuroptics, Inc. Pupilometer with pupil irregularity detection, pupil tracking, and pupil response detection capability, glaucoma screening capability, intracranial pressure detection capability, and ocular aberration measurement capability
US6116736A (en) * 1999-04-23 2000-09-12 Neuroptics, Inc. Pupilometer with pupil irregularity detection capability
US6887199B2 (en) 1999-09-23 2005-05-03 Active Signal Technologies, Inc. Brain assessment monitor
AUPQ896000A0 (en) 2000-07-24 2000-08-17 Seeing Machines Pty Ltd Facial image processing system
US7011410B2 (en) 2000-11-22 2006-03-14 Eyetect, L.L.C. Method and apparatus for monitoring eye tremor
US6572562B2 (en) 2001-03-06 2003-06-03 Eyetracking, Inc. Methods for monitoring affective brain function
EP1319361A1 (en) * 2001-12-17 2003-06-18 Maico Diagnostic GmbH Device for vision testing
JP4259160B2 (ja) 2002-08-01 2009-04-30 豊田合成株式会社 線状発光体
JP2004329879A (ja) 2003-02-07 2004-11-25 Nippon Syst Design Kk 眼球検査装置及び眼球検査方法
US7347551B2 (en) * 2003-02-13 2008-03-25 Fergason Patent Properties, Llc Optical system for monitoring eye movement
US7553021B2 (en) 2003-02-13 2009-06-30 Fergason Patent Properties, Llc Optical system for monitoring eye movement
US7401920B1 (en) 2003-05-20 2008-07-22 Elbit Systems Ltd. Head mounted eye tracking and display system
JP4179968B2 (ja) * 2003-11-13 2008-11-12 花王株式会社 リラックス感評価用瞳孔対光反応計測具
US20050165327A1 (en) 2004-01-28 2005-07-28 Thibault Lawrence E. Apparatus and method for detecting the severity of brain function impairment
JP4103829B2 (ja) 2004-03-26 2008-06-18 松下電工株式会社 眼球検査用ゴーグル
US20110077548A1 (en) 2004-04-01 2011-03-31 Torch William C Biosensors, communicators, and controllers monitoring eye movement and methods for using them
MXPA06011168A (es) 2004-04-01 2007-04-16 William C Torch Biosensores, comunicadores, y controladores que verifican el movimiento del ojo y metodos para utilizarlos.
WO2006091893A2 (en) 2005-02-23 2006-08-31 Eyetracking, Inc. Mental alertness level determination
US7438418B2 (en) 2005-02-23 2008-10-21 Eyetracking, Inc. Mental alertness and mental proficiency level determination
WO2006092022A1 (en) 2005-03-04 2006-09-08 Sleep Diagnostics Pty. Ltd Measuring alertness
DE102005024796A1 (de) * 2005-05-26 2006-11-30 Oculometrics Ag Verfahren und Vorrichtung zum Bestimmen neurologischer Beeinträchtigungen
US7216978B2 (en) * 2005-06-08 2007-05-15 Johnson & Johnson Vision Care, Inc. Method for evaluating eyelid movement and contact lens position
US7720530B2 (en) 2005-08-02 2010-05-18 Brainscope Company, Inc. Field-deployable concussion detector
US7647098B2 (en) 2005-10-31 2010-01-12 New York University System and method for prediction of cognitive decline
JP2007255669A (ja) 2006-03-24 2007-10-04 Tokai Rubber Ind Ltd クイックコネクタ
US7771353B2 (en) * 2006-04-11 2010-08-10 Reichert, Inc. Method and apparatus for tear film measurement
WO2007128034A1 (en) * 2006-05-01 2007-11-15 Eye Diagnostics Pty Ltd Portable eye monitoring device and methods for using the same
US8207963B2 (en) * 2006-07-31 2012-06-26 Onlive, Inc. System and method for performing motion capture and image reconstruction
WO2008137863A2 (en) 2007-05-04 2008-11-13 Advanced Medical Optics, Inc. Methods and devices for measuring tear film and diagnosing tear disorders
US7959293B2 (en) 2007-05-04 2011-06-14 Abbott Medical Optics Inc. Methods and devices for measuring tear film and diagnosing tear disorders
AT505338B1 (de) 2007-06-12 2009-03-15 Ernst Dipl Ing Dr Pfleger Verfahren zur wahrnehmungsmessung
US8393734B2 (en) 2007-09-14 2013-03-12 Neuroptics, Inc. Pupilary screening method and system
US7614745B2 (en) 2007-11-02 2009-11-10 Visionetx, Inc. System for analyzing eye responses to automatically determine impairment of a subject
US7938785B2 (en) 2007-12-27 2011-05-10 Teledyne Scientific & Imaging, Llc Fusion-based spatio-temporal feature detection for robust classification of instantaneous changes in pupil response as a correlate of cognitive response
US7810928B2 (en) 2008-02-26 2010-10-12 Konan Medical Usa, Inc. Evaluating pupillary responses to light stimuli
US8702236B2 (en) * 2008-03-04 2014-04-22 Procyon Instruments Limited Binocular pupillometers
US8209004B2 (en) 2008-06-23 2012-06-26 Freer Logic, Llc Body-based monitoring of brain electrical activity
JP5255063B2 (ja) 2008-09-18 2013-08-07 学校法人中部大学 眠気予兆検出装置
WO2010062400A1 (en) * 2008-11-28 2010-06-03 Neuroptics, Inc. Methods, systems, and devices for monitoring anisocoria and asymmetry of pupillary reaction to stimulus
JP5270415B2 (ja) 2009-03-19 2013-08-21 トヨタ自動車株式会社 眠気判定装置及びプログラム
EP2237237B1 (en) 2009-03-30 2013-03-20 Tobii Technology AB Eye closure detection using structured illumination
CN103251375B (zh) 2009-04-01 2016-09-28 眼泪科学公司 用于成像和测量泪液膜层一个或多个厚度的仪器
CL2009001908A1 (es) 2009-09-28 2011-07-22 Onirica Desarrollo De Tecnologias Ltda Un dispositivo para deteccion y alerta de estados de somnolencia en una actividad de seguridad de un usuario.
JP5613528B2 (ja) 2009-11-12 2014-10-22 パナソニック株式会社 眼電位計測装置、眼科診断装置、視線検出装置、ウェアラブルカメラ、ヘッドマウントディスプレイ、電子めがね、眼電位計測方法、及びプログラム
GB0920809D0 (en) 2009-11-27 2010-01-13 Qinetiq Ltd Eye tracking apparatus
US9298985B2 (en) 2011-05-16 2016-03-29 Wesley W. O. Krueger Physiological biosensor system and method for controlling a vehicle or powered equipment
US20120008091A1 (en) * 2010-07-06 2012-01-12 Stewart Charles W Evaluating pupillary responses to light stimuli
JP6066913B2 (ja) * 2010-11-08 2017-01-25 オプタラート・オーストラリア・プロプライエタリー・リミテッド 作業テストへの適応性
US20120238831A1 (en) 2011-03-18 2012-09-20 Jacob Benford Portable Neurocognitive Assesment and Evaluation System
US8911087B2 (en) 2011-05-20 2014-12-16 Eyefluence, Inc. Systems and methods for measuring reactions of head, eyes, eyelids and pupils
US20120330178A1 (en) 2011-06-24 2012-12-27 U.S. Government As Represented By The Secretary Of The Army Method and apparatus for multimodal mobile screening to quantitatively detect brain function impairment
US9155489B2 (en) 2011-07-05 2015-10-13 Deborah Zelinsky Devices for modulation of retinal stimulation and/or retinal signal processing and methods of use thereof
JP6316941B2 (ja) 2013-05-01 2018-04-25 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント 神経機能状態の監視
JP6227996B2 (ja) * 2013-12-18 2017-11-08 浜松ホトニクス株式会社 計測装置及び計測方法
EP3180080B1 (en) 2014-08-14 2021-01-06 Functional Neuromodulation, Inc. Brain stimulation system including multiple stimulation modes
KR102072788B1 (ko) 2015-04-30 2020-03-12 삼성전자주식회사 휴대 장치 및 휴대 장치의 콘텐트 화면 변경방법

Also Published As

Publication number Publication date
US20160073874A1 (en) 2016-03-17
EP2991542A1 (en) 2016-03-09
US11642021B2 (en) 2023-05-09
EP2991542B1 (en) 2025-12-24
US10448825B2 (en) 2019-10-22
EP2991542A4 (en) 2017-04-12
US20200000334A1 (en) 2020-01-02
AU2014259786A1 (en) 2015-11-19
CA2909785A1 (en) 2014-11-06
BR112015027598A2 (pt) 2017-09-19
CA2909785C (en) 2023-09-26
JP2016520381A (ja) 2016-07-14
WO2014179558A1 (en) 2014-11-06
US20240032788A1 (en) 2024-02-01
AU2014259786B2 (en) 2016-11-10

Similar Documents

Publication Publication Date Title
US20240032788A1 (en) Monitoring neurological functional status
JP7426698B2 (ja) 神経機能状態を監視するためのデバイス、システム、および方法
US11389059B2 (en) Ocular-performance-based head impact measurement using a faceguard
US12042294B2 (en) Systems and methods to measure ocular parameters and determine neurologic health status
US11490809B2 (en) Ocular parameter-based head impact measurement using a face shield
US9101312B2 (en) System for the physiological evaluation of brain function
JP6129161B2 (ja) 頭部、眼、眼瞼および瞳孔の反応を測定するためのシステムおよび方法
EP3607872B1 (en) Vision screening device and methods
US8668337B2 (en) System for the physiological evaluation of brain function
JP6774136B2 (ja) 自動視力診断の方法およびシステム
JP4179968B2 (ja) リラックス感評価用瞳孔対光反応計測具
US20180206773A1 (en) Dynamic assessment and rehabilitation system for vertigo patients and the application method thereof
US12178510B2 (en) Determining a visual performance of an eye of a person
Proctor et al. Sensation and perception
TWM561291U (zh) 疲勞警報裝置
KR20220039769A (ko) 원근조절 및 이접의 공동 결정
KR20170026925A (ko) 뇌파를 이용한 스마트 글라스
KR20170026922A (ko) 뇌파를 이용한 스마트 글라스의 구동 방법
US20230320640A1 (en) Bidirectional sightline-position determination device, bidirectional sightline-position determination method, and training method
TW201917703A (zh) 疲勞警報方法及其裝置
CN108597183A (zh) 一种疲劳警报方法及装置

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170426

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170426

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180227

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180228

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180328

R150 Certificate of patent or registration of utility model

Ref document number: 6316941

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250