JP6306318B2 - Cloudy aqueous topical skin composition - Google Patents

Description

The present invention relates to a water-based external composition for skin that is substantially clouded in appearance and does not substantially contain an oil agent and a surfactant.

Our skin dries when exposed to low-temperature and low-humidity environments in winter, resulting in fine lines and rough skin caused by drying. On the other hand, during the four seasons of the year, our skin is constantly affected by the external environment, such as being exposed to high-temperature and high-humidity environments, and sebum secretion increases and sticks, making it easier to cause acne. I keep receiving it. Various cosmetic preparations have been developed in response to such changes in the skin caused by environmental changes. Cosmetic preparations include aqueous lotions, emulsions, creams, gel dosage forms, etc. Among them, lotions are the most widely used items because they are basic cosmetic functions such as hydration and moisturizing the skin. ing. However, compared with milky lotion, cream, etc., cosmetic lotion has the disadvantages that it has poor moisturizing sustainability as a cosmetic function, and further, in terms of usability, it has a low-class feeling and a sense of effect due to its appearance as a transparent liquid.

As described above, skin toners are generally transparent in appearance, but some skin toners are partially translucent or cloudy. These have been developed by various devices since they have a high-quality feeling and an effect that are more apparent than the lotion having a transparent appearance. For example, it is known that an oil agent is blended and emulsified to make it milky white (for example, Patent Document 1), or by dispersing an inorganic powder or the like (for example, Patent Document 2). However, in these methods, the feeling of use of oils, powders, etc. appears directly, and the original function and feeling of use as a lotion are impaired. For example, emulsifying and blending an oil with lotion will cause the stickiness inherent in the lotion, such as the occurrence of stickiness peculiar to oils and surfactants, and the familiarity of the lotion due to the effect of the oil. The familiarity) will be impaired. In addition, when powder is added to lotion, it is a basic function of lotion due to the water absorption and oil absorption characteristics of the powder in addition to the adverse effects on the feeling of use such as the squeakiness peculiar to powder. It will greatly reduce the moisture retention of the skin. Furthermore, from the viewpoint of these stability, formulation stability such as the appearance of white turbidity changes greatly due to the destruction of emulsified particles and the precipitation of inorganic powder under high or low temperature conditions. Also have problems. In addition, in order to blend (emulsify and disperse) oils and powders, the use of a surfactant is essential, and therefore, irritation to the skin is inevitable to some extent.

On the other hand, fermented cereals are known to be used as emulsifiers (Patent Document 3). These fermented products contain many organic substances such as proteins, peptides, amino acids, sugars, alcohols and the like. Therefore, it is known that an oil agent etc. can be emulsified and that a more stable emulsifier form can be prepared by using an alkyl-modified carboxyvinyl polymer (Patent Document 4). However, by using this fermented cereal as a dispersed material, not as an emulsifier, it provides a dosage form that has a white turbid appearance with a sense of quality and effect without using an oil or a surfactant. In addition, in sensory evaluation of actual use, there are no disadvantages when blending emulsions and powders, etc., and it has a high-class feeling and effect feeling and use feeling that are not found in mere transparent lotions, high moisture retention, Furthermore, it is not known at all that stable turbidity can be maintained under various temperature conditions.

JP 2003-342116 A JP-A-11-116432 JP 2001-212445 A JP 2009-13100 A

In an aqueous external composition for skin with a cloudy appearance that does not substantially contain an oil agent and a surfactant, it has a high-quality feeling, an actual feeling of effect, a feeling of use, a high moisture retention, and a white turbidity at various temperature conditions. The task was to maintain high stability.

In view of such a situation, the present inventors used various raw materials used in the cosmetics field in combination, and as a result of earnest research aiming at solving the above-mentioned problems, the skin external application as shown below The present inventors have found that a composition can solve the above-mentioned problems and have completed the present invention. That is, the present invention is as follows.

<1> (a) Fermented cereal, (b) Thickening polymer that is not alkyl-modified, (c) A white turbid aqueous skin preparation that contains no polyhydric alcohol and contains substantially no oil and surfactant. Composition.
<2> The composition for external use as described in <1>, comprising a hydroxylated phospholipid.
<3> The external composition for skin according to <1> or <2>, wherein the thickening polymer that is not alkyl-modified is a carboxyvinyl polymer or xanthan gum.
<4> The external composition for skin according to any one of <1> to <3>, wherein the fermented cereal is fermented with lactic acid bacteria.
<5> The external composition for skin according to <4>, wherein the fermented cereal is a fermented lactic acid bacterium of rice.
<6> The external composition for skin according to <1> to <5>, wherein the viscosity is 300 to 5000 mPa · s.
<7> Grain lactic acid bacteria fermented product, polyhydric alcohol, and hydroxylated phospholipid are mixed, and then carboxyvinyl polymer or xanthan gum is added, and substantially contains an oil agent and a surfactant. A method for preparing a white cloudy aqueous skin external composition.

According to the present invention, in an aqueous skin external composition that is substantially clouded in appearance and contains substantially no oil agent and surfactant, it is possible to enhance the high-quality feeling, the effect feeling, the feeling of use, the moisture retention, and various temperatures. High stability can be maintained in the white turbidity under conditions.

<1> Fermented cereal used in the present invention The fermented cereal used in the present invention is obtained by oxidizing an organic compound by a microorganism such as yeast to obtain energy under anaerobic conditions, Of these, fermented lactic acid bacteria are preferred. Lactic acid bacteria can be used without particular limitation as long as they are normally recognized as lactic acid bacteria. Specifically, Lactobacillus plantarum, L. brevis, Lactobacillus casei (L. casei), Lactobacillus cellobiosus (L. cellobiosus), L. vaccinostercus, Streptococcus faecalis, Bacillus coagulans and the like, preferably Lactobacillus plan Talam (Lactobacillus plantarum) is particularly preferred. Inoculation and fermentation of such bacteria may be carried out in accordance with conventional methods, for example, an anaerobic condition may be performed at a fermentation temperature of 35 to 40 ° C. for 1 to 14 days. If desired, glucose, fructose, galactose, shoe Sugars such as Claus can also be added. The fermented product thus obtained can be used as it is, or can be used after removing the liquid phase part or removing the volatile component.

Moreover, as a grain used for fermentation, for example, rice, barley, wheat, oats, oats, buckwheat, soybeans, millet, straw, millet, amaranth and the like can be preferably exemplified, among which rice is particularly preferable. The rice is not particularly limited as long as it is a seed of a plant classified botanically as a rice of the family Gramineae. The processing state of the seed into rice is not particularly limited, and may be, for example, germinated rice or preserved rice that does not germinate, brown rice, five-minute rice, seven-minute rice, or brown rice. A fermented cereal is obtained by boiling, cooking, or steaming such cereal, cooling the softly processed product to an appropriate temperature, and then planting and fermenting the fungus. Such fermented lactic acid bacteria of grains can be prepared and used as described above, but there are already commercial products as cosmetic raw materials, and such commercial products can be purchased and used. Preferred examples include “Laughlin (registered trademark) AM” manufactured by Technoble Co., Ltd. Such a fermented cereal is preferably contained in an amount of 0.2% by mass to 10% by mass and more preferably 0.3% by mass to 2% by mass with respect to the total amount of the cosmetic.

<2> Non-alkyl-modified thickening polymer used in the present invention The non-alkyl-modified thickening polymer used in the present invention is a polymer capable of remarkably increasing viscosity by being dispersed and dissolved in water in a small amount. . Preferred examples include carboxyvinyl polymer, xanthan gum, hydroxyethyl cellulose, alginic acid and the like, and carboxyvinyl polymer and xanthan gum are more preferred. However, the alkyl-modified thickening polymer is not preferable because it does not increase the viscosity but causes gelation, which is not in the state of lotion or thick essence. Such a thickening polymer that is not alkyl-modified is preferably contained in an amount of 0.05% by mass to 0.5% by mass, more preferably 0.15% by mass to 0.35% by mass, based on the total amount of the cosmetic. .

<3> Polyhydric alcohol used in the present invention The polyhydric alcohol used in the present invention is not particularly limited as long as it is usually used in cosmetics. Examples include polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene glycol, dipropylene glycol, diglycerin, and isoprene glycol. Glycerin is more preferred.

<4> Hydroxylated phospholipid used in the present invention The hydroxylated phospholipid used in the present invention is obtained by oxidizing the unsaturated bond present in the acyl group of the phospholipid to form a dihydroxy body. There is no particular limitation as long as it is used in cosmetics, for example, lecithin, phosphatidic acid, phosphatidylglycerol, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, or lysates thereof. A body can be illustrated preferably. The double bond of the acyl group of such phospholipid is defined as an epoxide using an oxidizing agent such as benzoyl peroxide, and then water is added to lead to the dihydroxy form, which is defined as a hydroxylated phospholipid. Such hydroxylated phospholipids already exist in the market, and such commercial products can be purchased and used. As a preferable commercial product, for example, “NIKKOL” is a mixture of equal amounts of hydroxylated lecithin and glycerin based on soybean.
A preferred example is “Resinol SH50” (manufactured by Nippon Surfactant Co., Ltd.). These hydroxylated phospholipids can contain only one species, or can contain two or more species in combination. Such phospholipid is preferably contained in an amount of 0.01% by mass to 1.0% by mass and more preferably 0.05% by mass to 0.5% by mass with respect to the total amount of the cosmetic.

<5> Cloudy aqueous skin external composition substantially free of oil and surfactant of the present invention The skin external composition of the present invention is substantially cloudy free of oil and surfactant. It is an aqueous form. Examples of the oil agent include hydrocarbon oil, ester oil, triglyceride oil, silicone oil, and fragrance. Even if the oil agent is blended within a range that does not affect the cloudiness caused by the fermented cereal, there is no problem in the present invention. Although the concentration varies depending on the type of oil, the concentration is about 0.5% by mass at the upper limit. Up to about 0.1% by mass is more preferable, and it is more preferable that no oil is contained. Examples of the surfactant include nonionic surfactants and ionic surfactants. Nonionic surfactants include polyoxyethylene fatty acid esters, polyoxyethylene alkyl ethers, polyglycerin fatty acid esters, sucrose fatty acid esters, sorbitan fatty acid esters, and the like. Examples of the ionic surfactant include a cationic surfactant, an anionic surfactant, and an amphoteric surfactant. However, the hydroxylated phospholipid used in the present invention is not included in the surfactant in the present technology. Even if the surfactant is blended in a range that does not affect the cloudiness caused by the fermented cereal, there is no problem in the present invention. Although the concentration varies depending on the type of the surfactant, the concentration is about 0.3% by mass at the upper limit. Up to about 0.01% by mass is more preferable, and it is even more preferable that no surfactant is contained.

Specific examples of oils include macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, hardened coconut oil, hardened oil Oil, wax, liquid paraffin, squalane, pristane, ozokerite, paraffin, ceresin, petrolatum, microcrystallin, oil, wax, liquid oil, waxy wax, liquid paraffin, squalane, pistol, bean wax, bean wax, candelilla wax, carnauba wax, ibotarou, lanolin, reduced lanolin Hydrocarbons such as wax, higher alcohols such as cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, octyldodecanol, myristyl alcohol, cetostearyl alcohol, lauric acid, milli Higher fatty acids such as chic acid, stearic acid, behenic acid, cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebacate, cetyl lactate, diisostearyl malate, di-2 -Ethylene glycol ethylhexanoate, neopentyl glycol dicaprate, glycerin di-2-heptylundecanoate, glycerin tri-2-ethylhexanoate, trimethylolpropane tri-2-ethylhexanoate, trimethylolpropane triisostearate, tetra Synthetic ester oils such as 2-ethylhexanoic acid pentane erythritol, dimethicone, phenyl dimethicone, polyether-modified silicone, polyglycerin-modified silicone, amino-modified silicone Corn acids, diethylamino hydroxybenzoyl hexyl benzoate, t- butyl methoxybenzoyl methane, paramethoxy 2-ethylhexyl, dimethicone co diethyl benzalmalonate, UV absorbers such as homomenthyl oil-soluble vitamins and the like.

Specific examples of the surfactant include fatty acid soap (sodium laurate, sodium palmitate, etc.), anionic surfactants such as potassium lauryl sulfate, alkyl sulfate triethanolamine ether, stearyltrimethylammonium chloride, benzalkonium chloride, Cationic surfactants such as laurylamine oxide, imidazoline amphoteric surfactants (such as 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt), betaine surfactants (alkyl betaines, Amidobetaines, sulfobetaines, etc.), amphoteric surfactants such as acylmethyltaurine, sorbitan fatty acid esters (sorbitan monostearate, sorbitan sesquioleate, etc.), glycerin fatty acids (glyceryl monostearate) Propylene glycol fatty acid esters (such as propylene glycol monostearate), hydrogenated castor oil derivatives, glycerin alkyl ether, POE sorbitan fatty acid esters (POE sorbitan monooleate, polyoxyethylene sorbitan monostearate, etc.), POE sorbit Fatty acid esters (POE-sorbitol monolaurate, etc.), POE glycerin fatty acid esters (POE-glycerin monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2) -Octyldodecyl ether, etc.), POE alkyl phenyl ethers (POE nonyl phenyl ether, etc.), Pluronic types, POE / POP alkyl ether Nonionic surface actives such as POE / POP2-decyltetradecyl ether, Tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), sucrose fatty acid esters, alkyl glucosides, etc. Examples are agents.

The cloudy state is not transparent in appearance but translucent to opaque, and the whiteness varies depending on the fermented cereal used. The white turbidity is preferably in the range of 1 to 20% when measured with a spectrophotometer (for example, when measured with a transmittance at a measurement wavelength of 850 nm using a Shimadzu UV-visible spectrophotometer UV-1800). The aqueous form includes a lotion dosage form that does not use a thickening polymer to an essence dosage form with a little thickness, and the viscosity is preferably 100 to 8000 mPa · s, more preferably 300 to 5000 mPa · s. 1000 to 3000 mPa · s is more preferable. The skin external preparation as used in the present invention is not particularly limited as long as it is externally administered to the skin, and examples thereof include cosmetics including quasi-drugs, and skin external goods. Of these, cosmetics are particularly preferred. Although it is applicable to any of basic cosmetics, hair cosmetics, and makeup cosmetics, it is particularly preferable to apply to basic cosmetics.

In the external preparation for skin of the present invention, in addition to the above-mentioned components, optional components that are usually used in cosmetics and external preparations for skin can be contained. Examples of such optional components include lower alcohols such as ethanol and isopropanol, polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene glycol, dipropylene glycol, diglycerin, Moisturizing of polyhydric alcohols such as isoprene glycol, 1,2-pentanediol, 2,4-hexylene glycol, 1,2-hexanediol, 1,2-octanediol, sodium pyrrolidonecarboxylate, lactic acid, sodium lactate Classification, guar gum, quince seed, carrageenan, galactan, gum arabic, pectin, mannan, starch, xanthan gum, curdlan, methylcellulose, hydroxyethylcellulose, carboxyme Cellulose, methyl hydroxypropyl cellulose, chondroitin sulfate, dermatan sulfate, glycogen, heparan sulfate, hyaluronic acid, sodium hyaluronate, tragacanth gum, keratan sulfate, chondroitin, mucoitin sulfate, hydroxyethyl guar gum, carboxymethyl guar gum, dextran, kerato sulfate, locust Thickeners such as bean gum, succinoglucan, caronic acid, chitin, chitosan, carboxymethylchitin, agar, polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymer, sodium polyacrylate, polyethylene glycol, bentonite, etc. have been treated Mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, silicic anhydride (silica), oxidized aluminum Powders such as Ni and Barium sulfate, surface may be treated, inorganic pigments such as bengara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, bitumen, titanium oxide, zinc oxide, surface treated Pearl agents such as titanium mica, fish phosphorous foil, bismuth oxychloride, red 202, red 228, red 226, yellow 4, blue 404, yellow 5 No., Red No. 505, Red No. 230, Red No. 223, Orange No. 201, Red No. 213, Yellow No. 204, Yellow No. 203, Blue No. 1, Green No. 201, Purple No. 201, Red No. 204, etc. Preferred examples include organic powders such as polyethylene powder, polymethyl methacrylate, nylon powder, and organopolysiloxane elastomer.

Hereinafter, the present invention will be described in detail with reference to examples, but it is needless to say that the present invention is not limited to such examples.

<Production Example 1> Production of external composition for skin of the present invention An external composition for skin was prepared according to the formulation shown in Table 1 (Example 1). That is, (B) was added to (A), and (C) was further added and mixed to prepare a skin external composition. Further, referring to Example 1, Example 2-9 and Comparative Example 1-8 were prepared simultaneously. Shown in Tables 1 and 2. At the same time, the viscosity was measured (Shibaura System, DIGITAL VISMETRON VDA). Example 1 was 2900 mPa · s, Example 8 was 7980 mPa · s, Comparative Example 5 was 10200 mPa · s, and Comparative Example 6 was 80 mPa · s. there were.

<Test Example 1> Specialized panel evaluation Women special panels (10 persons) were allowed to use the external preparations for skin shown in the examples and comparative examples, and "high-quality feeling", "effect feeling (appearance)", "stickiness", " A questionnaire was conducted on the four items “feeling of squeaking”, and the evaluation was performed according to the following evaluation criteria. Table 3 shows the results.

"luxury"
1: Very present 2: Present 3: Neither 4: No effect “feeling (appearance)”
1: Very present 2: Present 3: Neither 4: No “stickiness”
1: Not present 2: Almost absent 3: Slightly present 4: Existence of “squeaking”
1: Not present 2: Almost absent 3: Slightly present 4: Present

<Test Example 2> The moisture retention evaluation test was conducted in a room at 20 ° C. and 50% relative humidity for 20 panelists. For the skin on the inner side of the forearm, the measurement site was washed with warm water at 37 ° C. for 30 seconds, allowed to rest for 20 minutes, and then measured with SKICON-200EX (manufactured by IBS) (initial value). Thereafter, the test samples shown in Tables 1 and 2 were applied once a day, and after one week, the skin moisture content was measured again in the same procedure. Table 4 shows the increase (μS) in the measured value after 1 week with respect to the initial value.

<Test Example 3> Measurement of white turbidity The composition for external use in skin prepared in Production Example 1 was stored at 20 ° C. for 1 day, and the white turbidity was measured. Then, it stored at 5 degreeC, 20 degreeC, and 40 degreeC, and measured again after one week and one month. In the measurement, a Shimadzu UV-Visible spectrophotometer UV-1800 was used and the transmittance was measured at a measurement wavelength of 850 nm. Those that have changed to a gel state due to the influence of time and temperature, and those that have been separated into two phases due to creaming or poor emulsification are not suitable as a composition for external use on the skin, and thus are not measured. The results are shown in Table 5.

From the results of Tables 3 to 5, the composition for external use of the skin according to the present invention can enhance the high-quality feeling, the effect feeling, the feeling of use, and the moisture retention, and can maintain high stability in the turbidity at various temperature conditions. I know that there is.

The present invention can enhance the high-class feeling, the effect feeling, the feeling of use, the moisture retention, and maintain high stability in the white turbidity at various temperature conditions, and substantially contains an oil agent and a surfactant. The present invention can be applied to a water-based external composition for skin having a cloudy appearance.

Claims (6)

(A) Fermentation of cereal, (b) thickening polymer not alkyl-modified, see contains (c) a polyhydric alcohol further comprises a hydroxide phospholipid content of oil is 0.5 wt% or less A white turbid aqueous composition for external skin , wherein the surfactant content is 0.3% by mass or less . The composition for external use according to claim 1, wherein the thickening polymer that is not alkyl-modified is carboxyvinyl polymer or xanthan gum. The external composition for skin according to claim 1 or 2 , wherein the fermented cereal is fermented with lactic acid bacteria. The external composition for skin according to claim 3 , wherein the fermented cereal is a fermented lactic acid bacterium of rice. The composition for external use according to any one of claims 1 to 4, wherein the viscosity is 300 to 5000 mPa · s. After mixing cereal lactic acid bacteria fermented product, polyhydric alcohol, and hydroxylated phospholipid, carboxyvinyl polymer or xanthan gum is added, and the content of oil is 0.5% by mass or less, and the interface A method for preparing a white turbid aqueous skin external composition having an active agent content of 0.3% by mass or less .