JP6297490B2 - 診断マーカー - Google Patents

診断マーカー Download PDF

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Publication number
JP6297490B2
JP6297490B2 JP2014528597A JP2014528597A JP6297490B2 JP 6297490 B2 JP6297490 B2 JP 6297490B2 JP 2014528597 A JP2014528597 A JP 2014528597A JP 2014528597 A JP2014528597 A JP 2014528597A JP 6297490 B2 JP6297490 B2 JP 6297490B2
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JP
Japan
Prior art keywords
methylation
erbb2 gene
cancer
erbb2
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2014528597A
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English (en)
Japanese (ja)
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JP2014525270A5 (https=
JP2014525270A (ja
Inventor
デーヴィッド シャムズ，
デーヴィッド シャムズ，
トーマス イー． ジャヌアーリオ，
トーマス イー． ジャヌアーリオ，
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Genentech Inc
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Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46826936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP6297490(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2014525270A publication Critical patent/JP2014525270A/ja
Publication of JP2014525270A5 publication Critical patent/JP2014525270A5/ja
Application granted granted Critical
Publication of JP6297490B2 publication Critical patent/JP6297490B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2014528597A 2011-08-31 2012-08-30 診断マーカー Expired - Fee Related JP6297490B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161529917P 2011-08-31 2011-08-31
US61/529,917 2011-08-31
PCT/US2012/053114 WO2013033380A1 (en) 2011-08-31 2012-08-30 Diagnostic markers

Publications (3)

Publication Number Publication Date
JP2014525270A JP2014525270A (ja) 2014-09-29
JP2014525270A5 JP2014525270A5 (https=) 2015-03-05
JP6297490B2 true JP6297490B2 (ja) 2018-03-20

Family

ID=46826936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014528597A Expired - Fee Related JP6297490B2 (ja) 2011-08-31 2012-08-30 診断マーカー

Country Status (13)

Country Link
US (4) US20130084286A1 (https=)
EP (1) EP2751285B2 (https=)
JP (1) JP6297490B2 (https=)
KR (1) KR20140057356A (https=)
CN (1) CN104024432B (https=)
AU (1) AU2012301889B2 (https=)
BR (1) BR112014004762A2 (https=)
CA (1) CA2845179A1 (https=)
IL (1) IL230851A0 (https=)
MX (1) MX2014002436A (https=)
RU (1) RU2614254C2 (https=)
SG (1) SG2014011316A (https=)
WO (1) WO2013033380A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9984201B2 (en) * 2015-01-18 2018-05-29 Youhealth Biotech, Limited Method and system for determining cancer status
CN109642257B (zh) * 2016-06-10 2022-08-12 国立研究开发法人国立癌症研究中心 药物疗法对癌的效果的预测方法
CN113151458A (zh) 2016-07-06 2021-07-23 优美佳肿瘤技术有限公司 实体瘤甲基化标志物及其用途
BR112019018272A2 (pt) 2017-03-02 2020-07-28 Youhealth Oncotech, Limited marcadores metilação para diagnosticar hepatocelular carcinoma e câncer
CN110511997A (zh) * 2018-05-22 2019-11-29 广州市康立明生物科技有限责任公司 肿瘤标志物、甲基化试剂、试剂盒及其应用

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Also Published As

Publication number Publication date
BR112014004762A2 (pt) 2018-06-19
US11261498B2 (en) 2022-03-01
US20170306419A1 (en) 2017-10-26
HK1199475A1 (en) 2015-07-03
US20200024670A1 (en) 2020-01-23
CN104024432B (zh) 2017-02-22
IL230851A0 (en) 2014-03-31
RU2614254C2 (ru) 2017-03-24
US20150086543A1 (en) 2015-03-26
CA2845179A1 (en) 2013-03-07
WO2013033380A1 (en) 2013-03-07
EP2751285B1 (en) 2017-03-01
MX2014002436A (es) 2014-05-27
CN104024432A (zh) 2014-09-03
SG2014011316A (en) 2014-06-27
KR20140057356A (ko) 2014-05-12
RU2014110895A (ru) 2015-10-10
AU2012301889B2 (en) 2016-04-21
US20130084286A1 (en) 2013-04-04
EP2751285A1 (en) 2014-07-09
EP2751285B2 (en) 2020-04-01
JP2014525270A (ja) 2014-09-29
AU2012301889A1 (en) 2014-03-06

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