JP6285921B2 - 超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 - Google Patents
超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 Download PDFInfo
- Publication number
- JP6285921B2 JP6285921B2 JP2015517277A JP2015517277A JP6285921B2 JP 6285921 B2 JP6285921 B2 JP 6285921B2 JP 2015517277 A JP2015517277 A JP 2015517277A JP 2015517277 A JP2015517277 A JP 2015517277A JP 6285921 B2 JP6285921 B2 JP 6285921B2
- Authority
- JP
- Japan
- Prior art keywords
- subarachnoid
- module
- hematoma
- thrombolytic agent
- delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/06—Measuring blood flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Clinical applications
- A61B8/0808—Clinical applications for diagnosis of the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/488—Diagnostic techniques involving Doppler signals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0021—Neural system treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0078—Ultrasound therapy with multiple treatment transducers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Radiology & Medical Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Mechanical Engineering (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pathology (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261659269P | 2012-06-13 | 2012-06-13 | |
| US61/659,269 | 2012-06-13 | ||
| PCT/US2013/042744 WO2013188084A1 (en) | 2012-06-13 | 2013-05-24 | Treatment of subarachnoid hematoma using sonothrombolysis and associated devices, systems and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015519970A JP2015519970A (ja) | 2015-07-16 |
| JP2015519970A5 JP2015519970A5 (https=) | 2016-07-07 |
| JP6285921B2 true JP6285921B2 (ja) | 2018-02-28 |
Family
ID=49756542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517277A Expired - Fee Related JP6285921B2 (ja) | 2012-06-13 | 2013-05-24 | 超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9808653B2 (https=) |
| EP (1) | EP2861300A4 (https=) |
| JP (1) | JP6285921B2 (https=) |
| WO (1) | WO2013188084A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10391285B2 (en) * | 2013-06-14 | 2019-08-27 | The Cleveland Clinic Foundation | Motion-assisted systems, devices and methods for minimizing obstruction of medical devices |
| US11191886B2 (en) | 2013-06-14 | 2021-12-07 | The Cleveland Clinic Foundation | Motion-assisted systems, devices and methods for minimizing obstruction of medical devices |
| US11432900B2 (en) | 2013-07-03 | 2022-09-06 | Histosonics, Inc. | Articulating arm limiter for cavitational ultrasound therapy system |
| US10780298B2 (en) | 2013-08-22 | 2020-09-22 | The Regents Of The University Of Michigan | Histotripsy using very short monopolar ultrasound pulses |
| WO2016075586A1 (en) | 2014-11-14 | 2016-05-19 | Koninklijke Philips N.V. | Ultrasound device for sonothrombolysis therapy |
| EP4230262A3 (en) * | 2015-06-24 | 2023-11-22 | The Regents Of The University Of Michigan | Histotripsy therapy systems for the treatment of brain tissue |
| US11484243B2 (en) * | 2016-08-12 | 2022-11-01 | Nuro Corp. | Portable Alzheimer detector |
| JP7042814B2 (ja) * | 2016-11-01 | 2022-03-28 | 日本光電工業株式会社 | 患者の頭部に配置されて当該患者の脳の皮質組織の脈動を測定するためのトランスデューサを含むシステム |
| CN113286552B (zh) | 2018-11-28 | 2025-05-02 | 希斯托索尼克斯公司 | 组织摧毁术系统及方法 |
| US20220132941A1 (en) * | 2019-02-15 | 2022-05-05 | Max BOYSSET | Article of clothing and method for controlling cells using such an article of clothing |
| WO2021155026A1 (en) | 2020-01-28 | 2021-08-05 | The Regents Of The University Of Michigan | Systems and methods for histotripsy immunosensitization |
| JP2023530477A (ja) | 2020-06-18 | 2023-07-18 | ヒストソニックス,インコーポレーテッド | 組織破砕音響/患者結合システムおよび方法 |
| EP4204084A4 (en) | 2020-08-27 | 2024-10-09 | The Regents Of The University Of Michigan | ULTRASONIC TRANSDUCER WITH TRANSMIT-RECEIVE CAPABILITY FOR HISTOTRIPSY |
| EP4351718A4 (en) | 2021-06-07 | 2025-03-26 | The Regents of The University of Michigan | MINIMALLY INVASIVE HISTOTRIPSY METHODS AND SYSTEMS |
| IL308943A (en) | 2021-06-07 | 2024-01-01 | Univ Michigan Regents | All-inclusive ultrasound systems and methods that include histotripsy |
| AU2023366591A1 (en) | 2022-10-28 | 2025-04-24 | Histosonics, Inc. | Histotripsy systems and methods |
| WO2024221001A2 (en) | 2023-04-20 | 2024-10-24 | Histosonics, Inc. | Histotripsy systems and associated methods including user interfaces and workflows for treatment planning and therapy |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03222961A (ja) * | 1990-01-29 | 1991-10-01 | Olympus Optical Co Ltd | 溶解治療装置 |
| CA2048120A1 (en) | 1990-08-06 | 1992-02-07 | William J. Drasler | Thrombectomy method and device |
| JP3300419B2 (ja) * | 1991-08-21 | 2002-07-08 | 株式会社東芝 | 血栓溶解治療装置 |
| US6635017B1 (en) * | 2000-02-09 | 2003-10-21 | Spentech, Inc. | Method and apparatus combining diagnostic ultrasound with therapeutic ultrasound to enhance thrombolysis |
| US6733450B1 (en) | 2000-07-27 | 2004-05-11 | Texas Systems, Board Of Regents | Therapeutic methods and apparatus for use of sonication to enhance perfusion of tissue |
| US20040209307A1 (en) * | 2001-08-20 | 2004-10-21 | Biosite Incorporated | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| JP2004024668A (ja) * | 2002-06-27 | 2004-01-29 | Hiroshi Furuhata | 経頭蓋超音波治療装置 |
| WO2004045672A2 (en) * | 2002-11-15 | 2004-06-03 | The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Variable curve catheter |
| EP1591073A4 (en) * | 2003-01-31 | 2010-11-17 | Hitachi Medical Corp | ULTRASONIC SOUND AND ULTRASONIC UNIT |
| US20040215067A1 (en) * | 2003-04-24 | 2004-10-28 | Stiger Mark L. | Flow sensor device for endoscopic third ventriculostomy |
| JP5004584B2 (ja) * | 2003-09-08 | 2012-08-22 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー | 拡張凝血塊溶解用の超音波装置 |
| US8409099B2 (en) * | 2004-08-26 | 2013-04-02 | Insightec Ltd. | Focused ultrasound system for surrounding a body tissue mass and treatment method |
| US8112154B2 (en) * | 2005-04-13 | 2012-02-07 | The Cleveland Clinic Foundation | Systems and methods for neuromodulation using pre-recorded waveforms |
| US20110313328A1 (en) * | 2005-06-24 | 2011-12-22 | Penumbra, Inc. | Methods and apparatus for dissolving blockages in intracranial catheters |
| US20110319927A1 (en) * | 2005-06-24 | 2011-12-29 | Penumbra, Inc. | Methods and apparatus for removing blood clots from intracranial aneurysms |
| US20080089848A1 (en) * | 2006-10-11 | 2008-04-17 | Dimauro Thomas | Intrathecal injection of microbubbles |
| JP5781727B2 (ja) * | 2007-02-23 | 2015-09-24 | 株式会社ネクスト21 | 血管攣縮の治療剤又は予防剤 |
| US20080294089A1 (en) * | 2007-06-06 | 2008-11-27 | Biovaluation & Analysis, Inc. | Dendritic Polymers for Use in Acoustically Mediated Intracellular Drug Delivery in vivo |
| ES2471118T3 (es) * | 2007-06-22 | 2014-06-25 | Ekos Corporation | Método y aparato para el tratamiento de hemorragias intracraneales |
| WO2010033875A1 (en) * | 2008-09-19 | 2010-03-25 | Physiosonics, Inc. | Acoustic palpation using non-invasive ultrasound techniques to identify and localize tissue eliciting biological responses |
| US8425424B2 (en) * | 2008-11-19 | 2013-04-23 | Inightee Ltd. | Closed-loop clot lysis |
| JP6291253B2 (ja) | 2010-08-27 | 2018-03-14 | イーコス・コーポレイシヨン | 超音波カテーテル |
| US8613714B2 (en) | 2010-10-05 | 2013-12-24 | Cerevast Therapeutics, Inc. | Non-invasive transcranial ultrasound apparatus |
| US8603014B2 (en) | 2010-10-05 | 2013-12-10 | Cerevast Therapeutics, Inc. | Hands-free operator-independent transcranial ultrasound apparatus and methods |
-
2013
- 2013-05-24 WO PCT/US2013/042744 patent/WO2013188084A1/en not_active Ceased
- 2013-05-24 EP EP13805170.1A patent/EP2861300A4/en not_active Withdrawn
- 2013-05-24 US US13/902,644 patent/US9808653B2/en not_active Expired - Fee Related
- 2013-05-24 JP JP2015517277A patent/JP6285921B2/ja not_active Expired - Fee Related
-
2017
- 2017-11-03 US US15/803,702 patent/US20180154187A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2861300A1 (en) | 2015-04-22 |
| US20180154187A1 (en) | 2018-06-07 |
| US20130338544A1 (en) | 2013-12-19 |
| EP2861300A4 (en) | 2016-03-16 |
| JP2015519970A (ja) | 2015-07-16 |
| US9808653B2 (en) | 2017-11-07 |
| WO2013188084A1 (en) | 2013-12-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6285921B2 (ja) | 超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 | |
| Spengos et al. | Acceleration of thrombolysis with ultrasound through the cranium in a flow model | |
| Hage et al. | Treatment of venous malformations: the data, where we are, and how it is done | |
| Shankar et al. | Potential adverse ultrasound-related biological effects: a critical review | |
| Wright et al. | In vitro and in vivo high-intensity focused ultrasound thrombolysis | |
| US6733450B1 (en) | Therapeutic methods and apparatus for use of sonication to enhance perfusion of tissue | |
| Hitchcock et al. | Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model | |
| US20230019961A1 (en) | Treating bleeding and bleeding disorders via high intensity focused ultrasound stimulation of the spleen | |
| US20160107002A1 (en) | Ischemic Stroke Therapy | |
| US20180001114A1 (en) | Automated ultrasound apparatus and method for noninvasive vessel recanalization treatment and monitoring | |
| JP2021513403A (ja) | 超音波血流モニタリング | |
| JP2003534032A (ja) | 診断用超音波と治療用超音波を合わせて血栓崩壊を増強する方法および装置 | |
| JP2015519970A5 (https=) | ||
| US20120029397A1 (en) | Tumor treatment using ultrasound cavitation | |
| US20250269181A1 (en) | Systems and methods for controlling against aneurysm formation, growth and rupture, and improving post-rupture outcomes | |
| Damianou et al. | MRI-guided sonothrombolysis of rabbit carotid artery | |
| Hoerig et al. | Prediction and suppression of HIFU-induced vessel rupture using passive cavitation detection in an ex vivo model | |
| Bor-Seng-Shu et al. | Sonothrombolysis for acute ischemic stroke: a systematic review of randomized controlled trials | |
| Papadopoulos et al. | In vitro evaluation of focused ultrasound-enhanced TNK-tissue plasminogen activator-mediated thrombolysis | |
| Barlinn et al. | Sonothrombolysis in ischemic stroke | |
| Eggers et al. | Enhanced clot dissolution in vitro by 1.8-MHz pulsed ultrasound | |
| Masomi-Bornwasser et al. | Systematic analysis of combined thrombolysis using ultrasound and different fibrinolytic drugs in an in vitro clot model of intracerebral hemorrhage | |
| Papadopoulos et al. | Microbubble-based sonothrombolysis using a planar rectangular ultrasonic transducer | |
| Fiorella et al. | O-027 The INVEST Trial: a randomized, controlled trial to investigate the safety and efficacy of image guided minimally invasive endoscopic surgery with Apollo vs best medical management for supratentorial intracerebral hemorrhage | |
| Stillo et al. | Glubran-2 Acrylic Glue for Percutaneous Embolization of Intramuscular Vascular Malformations of Lower Limbs: Preliminary Experience |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160520 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20160520 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170221 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170502 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170705 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170821 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180116 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180202 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6285921 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| LAPS | Cancellation because of no payment of annual fees |