JP6249591B2 - マイクロニードル - Google Patents
マイクロニードル Download PDFInfo
- Publication number
- JP6249591B2 JP6249591B2 JP2012039078A JP2012039078A JP6249591B2 JP 6249591 B2 JP6249591 B2 JP 6249591B2 JP 2012039078 A JP2012039078 A JP 2012039078A JP 2012039078 A JP2012039078 A JP 2012039078A JP 6249591 B2 JP6249591 B2 JP 6249591B2
- Authority
- JP
- Japan
- Prior art keywords
- hollow
- needle
- wall
- hollow needle
- microneedle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Description
実施例1として、中空針7の内径を50μmとし、その中空内壁に親水化処理(処理後の純水接触角10°)を施して親水処理層5を設け、気体が接している中空外壁に疎水化処理(処理後の純水接触角90°)を施して疎水処理層6を設けて中空針状体1を作製した。
実施例2として、中空針7の内径を20μmとし、中空内壁に親水化処理(処理後の純水接触角10°)を施して親水処理層5を設け、中空外壁に純水接触角が60°の疎水処理層6を設けて中空針状体1を作製した。
実施例3として、中空針7の内径を50μm、中空内壁に親水化処理(処理後の純水接触角10°)を施して親水処理層5を設け、中空外壁に純水接触角が40°の疎水処理層6を設けて中空針状体1を作製した。
実施例4として、中空針7の内径を100μm、中空内壁に親水化処理(処理後の純水接触角10°)を施して親水処理層5を設け、中空外壁の純水接触角が60°の疎水処理層6を設けて中空針状体1を作製した。
2 … 薬液
3 … 基板
4 … 支持体
5 … 親水処理層
6 … 疎水処理層
7 … 中空針
8 … 矢印
Claims (1)
- 水系溶液を充填液として使用する50μm〜1000μmの針長さ寸法を有した空洞状の複数の中空針が設けられた中空針状体を備えるマイクロニードルにおいて、
前記中空針は、中空断面平均直径が40〜70μmであり、
前記中空針の中空内壁は、親水性処理層が設けられており純水の接触角が0〜20°であり、かつ、
前記中空針の中空外壁は、疎水性処理層が設けられており純水の接触角が80〜120°であり、かつ、
前記充填液の吐出は、指先でおこなわれる
ことを特徴とする。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012039078A JP6249591B2 (ja) | 2012-02-24 | 2012-02-24 | マイクロニードル |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012039078A JP6249591B2 (ja) | 2012-02-24 | 2012-02-24 | マイクロニードル |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013172847A JP2013172847A (ja) | 2013-09-05 |
JP6249591B2 true JP6249591B2 (ja) | 2017-12-20 |
Family
ID=49266370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012039078A Active JP6249591B2 (ja) | 2012-02-24 | 2012-02-24 | マイクロニードル |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP6249591B2 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015151516A1 (ja) * | 2014-04-03 | 2015-10-08 | 凸版印刷株式会社 | 穿刺注入器具 |
CN104117137B (zh) * | 2014-07-08 | 2017-12-15 | 清华大学 | 一种胶囊式中空载药微针阵列及其制备方法 |
US11116954B2 (en) | 2016-02-15 | 2021-09-14 | Shanghai Jiao Tong University | Method to print microneedle patches rapidly |
JP6732373B2 (ja) * | 2016-03-31 | 2020-07-29 | 花王株式会社 | 微細中空突起具の製造方法、及び微細中空突起具 |
CN108853713B (zh) * | 2018-07-17 | 2023-11-10 | 优微(珠海)生物科技有限公司 | 一种微针经皮给药生物面膜 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4264269B2 (ja) * | 2003-01-30 | 2009-05-13 | 財団法人神奈川科学技術アカデミー | 親水性チューブおよびその製造方法 |
WO2007040938A1 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Functionalized microneedles transdermal drug delivery systems, devices, and methods |
JP5476062B2 (ja) * | 2008-07-25 | 2014-04-23 | 南部化成株式会社 | 経皮投薬デバイス |
JP2011083484A (ja) * | 2009-10-16 | 2011-04-28 | Toshiba Corp | 経皮薬物投与装置及び経皮薬物投与ユニット |
DK2563450T3 (da) * | 2010-04-28 | 2017-11-13 | Kimberly Clark Co | Apparat til administration af rheumatoid-arthritis-medikament |
-
2012
- 2012-02-24 JP JP2012039078A patent/JP6249591B2/ja active Active
Also Published As
Publication number | Publication date |
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JP2013172847A (ja) | 2013-09-05 |
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