JP6223444B2 - 蛋白質‐脂質複合体を用いた抗生物質治療の増強 - Google Patents

蛋白質‐脂質複合体を用いた抗生物質治療の増強 Download PDF

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JP6223444B2
JP6223444B2 JP2015520705A JP2015520705A JP6223444B2 JP 6223444 B2 JP6223444 B2 JP 6223444B2 JP 2015520705 A JP2015520705 A JP 2015520705A JP 2015520705 A JP2015520705 A JP 2015520705A JP 6223444 B2 JP6223444 B2 JP 6223444B2
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alafac
antibiotics
antibiotic
gentamicin
penicillin
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Japanese (ja)
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JP2015522040A5 (https=
JP2015522040A (ja
Inventor
ハッカンソン,アンダース,ピー.
マークス,ローラ,アール.
ハッカンソン,ヘイズライン
Original Assignee
ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク
ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2015520705A 2012-07-05 2013-07-05 蛋白質‐脂質複合体を用いた抗生物質治療の増強 Expired - Fee Related JP6223444B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261668390P 2012-07-05 2012-07-05
US61/668,390 2012-07-05
PCT/US2013/049437 WO2014008465A2 (en) 2012-07-05 2013-07-05 Potentiation of antibiotic treatment with a protein-lipid complex

Publications (3)

Publication Number Publication Date
JP2015522040A JP2015522040A (ja) 2015-08-03
JP2015522040A5 JP2015522040A5 (https=) 2016-08-25
JP6223444B2 true JP6223444B2 (ja) 2017-11-01

Family

ID=49882625

Family Applications (1)

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JP2015520705A Expired - Fee Related JP6223444B2 (ja) 2012-07-05 2013-07-05 蛋白質‐脂質複合体を用いた抗生物質治療の増強

Country Status (5)

Country Link
US (1) US9526766B2 (https=)
EP (1) EP2869831A4 (https=)
JP (1) JP6223444B2 (https=)
CA (1) CA2878292A1 (https=)
WO (1) WO2014008465A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101801521B (zh) 2007-05-14 2015-06-17 纽约州立大学研究基金会 生物膜中细菌细胞内的生理学分散响应诱导
CN104068123B (zh) * 2014-06-26 2016-06-22 南京医科大学 一种乳白蛋白和油酸复合物抗肿瘤的保健饮料及其制备方法
WO2018070874A1 (en) * 2016-10-12 2018-04-19 Rijksuniversiteit Groningen Means and methods for reducing or avoiding antibiotic resistance and spread of virulence in human pathogens
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1032596T3 (da) 1997-11-21 2007-09-10 Nya Hamlet Pharma Ab Fremgangsmåde til fremstilling af lactalbumin
GB9725126D0 (en) 1997-11-27 1998-01-28 Svanborg Catharina Therapeutic agents
EP2094309A2 (en) * 2006-11-17 2009-09-02 Nya Hamlet Pharma AB Alpha-lactalbumin composition
EP2512460A4 (en) * 2009-12-18 2015-01-21 Exodos Life Sciences Ltd Partnership METHOD AND COMPOSITIONS FOR STABLE LIQUID ACTIVE FORMULATIONS

Also Published As

Publication number Publication date
EP2869831A4 (en) 2016-04-06
WO2014008465A2 (en) 2014-01-09
JP2015522040A (ja) 2015-08-03
US20150148286A1 (en) 2015-05-28
CA2878292A1 (en) 2014-01-09
WO2014008465A3 (en) 2014-07-31
EP2869831A2 (en) 2015-05-13
US9526766B2 (en) 2016-12-27

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