JP6192537B2 - Ｔ細胞の標的抗原の同定 - Google Patents
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| SI2755997T1 (sl) | 2011-09-15 | 2018-11-30 | The United States of America, as represented by Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health | T-celični receptorji, ki prepoznajo HLA-A1- ali HLA-CW7-omejeni mage |
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| US20140065098A1 (en) * | 2012-08-29 | 2014-03-06 | Israel Barken | Method to augment immune system in response to disease or injury |
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| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
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| EP3112375A1 (en) | 2015-07-03 | 2017-01-04 | Ludwig-Maximilians-Universität München | Antigenic peptides for the diagnosis, therapy monitoring and/or treatment of psoriasis vulgaris |
| AU2016326734B2 (en) * | 2015-09-25 | 2022-07-07 | Abvitro Llc | High throughput process for T cell receptor target identification of natively-paired T cell receptor sequences |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| KR20180108567A (ko) | 2015-10-22 | 2018-10-04 | 주노 테라퓨틱스 게엠베하 | 형질도입을 위한 방법, 키트, 제제 및 장치 |
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| WO2017075141A1 (en) * | 2015-10-27 | 2017-05-04 | Arizona Board Of Regents On Behalf Of Arizona State University | High throughput identification of t-cell recognition antigens and epitopes |
| WO2017096329A1 (en) | 2015-12-03 | 2017-06-08 | Juno Therapeutics, Inc. | Modified chimeric receptors and related compositions and methods |
| CA3036992A1 (en) * | 2016-09-16 | 2018-03-22 | Memorial Sloan Kettering Cancer Center | Methods and compositions for t-cell epitope screening |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| CA3039420A1 (en) | 2016-11-07 | 2018-05-11 | Genovie Ab | A two-part device for t-cell receptor synthesis and stable genomic integration to tcr-presenting cells |
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| CN110036026B (zh) * | 2016-11-07 | 2024-01-05 | 杰诺维有限公司 | 用于发现和表征t细胞受体与相关抗原相互作用的工程化两部分细胞装置 |
| IL270142B2 (en) | 2017-04-27 | 2025-05-01 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| WO2018213803A1 (en) * | 2017-05-19 | 2018-11-22 | Neon Therapeutics, Inc. | Immunogenic neoantigen identification |
| EP3692058A1 (en) | 2017-10-06 | 2020-08-12 | Oslo Universitetssykehus HF | Chimeric antigen receptors |
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| JP7529265B2 (ja) | 2018-04-19 | 2024-08-06 | ベイラー カレッジ オブ メディスン | ＣＤ８ａｂおよびクラス１制限Ｔ細胞受容体の強制発現による細胞傷害性ＣＤ８細胞へのＣＤ４ Ｔ細胞の再プログラミング |
| JP7328631B2 (ja) * | 2018-08-24 | 2023-08-17 | Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 | Ｔ細胞受容体およびｂ細胞受容体の機能的なサブユニットペア遺伝子の解析方法 |
| CN114807125B (zh) * | 2022-05-20 | 2023-09-12 | 纳昂达(南京)生物科技有限公司 | 测序文库接头、测序文库及其构建方法、提升ngs建库连接效率的方法 |
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| US6037135A (en) | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
| US20010053523A1 (en) * | 1995-06-02 | 2001-12-20 | M&E Biotech A/S. | Method for identification of biologically active peptides and nucleic acids |
| DE69734974D1 (de) * | 1996-02-08 | 2006-02-02 | Us Gov Health & Human Serv | Verfahren zur transformation dendritischer zellen und aktivierung von t zellen |
| WO1998046739A1 (fr) * | 1997-04-16 | 1998-10-22 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Molecules immunomodulatrices et leur procede de production |
| US6872518B2 (en) * | 1997-09-22 | 2005-03-29 | University Of Rochester | Methods for selecting polynucleotides encoding T cell epitopes |
| DE10009341A1 (de) | 2000-02-22 | 2001-09-06 | Florian Kern | Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten |
| JP4812951B2 (ja) * | 2001-03-21 | 2011-11-09 | 一般財団法人化学及血清療法研究所 | 特異性不明のｔ細胞のクローン化法及びその認識ペプチドリガンドの同定方法 |
| ATE388448T1 (de) * | 2001-04-13 | 2008-03-15 | Inst Nat Sante Rech Med | Verfahren zur analyse von t-lymphozyten über die t-lymphozytrezeptoren eines organismus |
| US20030003485A1 (en) * | 2001-05-15 | 2003-01-02 | Ludwig Institute For Cancer Research | Methods for identifying antigens |
| US20030175250A1 (en) | 2002-02-13 | 2003-09-18 | Elke Jager | Isolated peptides which bind to HLA molecules and uses thereof |
| KR20080079243A (ko) | 2005-11-10 | 2008-08-29 | 유니버시티 오브 시카고 | Ｈｃｖ-반응성 ｔ 세포 수용체 |
| JP5292550B2 (ja) * | 2007-03-23 | 2013-09-18 | 静岡県 | Ｔ細胞レセプターβ鎖遺伝子及びα鎖遺伝子 |
| GB0712670D0 (en) * | 2007-06-29 | 2007-08-08 | King S College London | Isolated peptides and uses thereof |
| CN102066578B (zh) * | 2008-04-16 | 2016-07-06 | 哈森阿尔法生物技术研究院 | 用于评价和比较免疫组库的方法 |
| US7892202B2 (en) | 2008-05-09 | 2011-02-22 | Merit Medical Systems, Inc. | System and method for inflation syringe with improved display |
| GB2483810B (en) * | 2008-11-07 | 2012-09-05 | Sequenta Inc | Methods for correlating clonotypes with diseases in a population |
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| EP3376225A1 (en) | 2018-09-19 |
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| JP2017038609A (ja) | 2017-02-23 |
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| US20170240884A1 (en) | 2017-08-24 |
| US9678061B2 (en) | 2017-06-13 |
| EP2982766A1 (en) | 2016-02-10 |
| US20130195900A1 (en) | 2013-08-01 |
| EP2601521B1 (en) | 2018-05-02 |
| CA2806440A1 (en) | 2012-02-09 |
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