JP6177894B2 - チアジアゾールの調製方法 - Google Patents

チアジアゾールの調製方法 Download PDF

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Publication number
JP6177894B2
JP6177894B2 JP2015512873A JP2015512873A JP6177894B2 JP 6177894 B2 JP6177894 B2 JP 6177894B2 JP 2015512873 A JP2015512873 A JP 2015512873A JP 2015512873 A JP2015512873 A JP 2015512873A JP 6177894 B2 JP6177894 B2 JP 6177894B2
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JP
Japan
Prior art keywords
alkyl
aryl
ljr
groups
optionally substituted
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Expired - Fee Related
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JP2015512873A
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English (en)
Japanese (ja)
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JP2015517531A5 (enEXAMPLES
JP2015517531A (ja
Inventor
エリック エー． ベルコット，
エリック エー． ベルコット，
マシュー バイオ，
マシュー バイオ，
ヨハン チャン，
ヨハン チャン，
ジョン コリアー，
ジョン コリアー，
ユアンチン ファン，
ユアンチン ファン，
スティーブン メネン，
スティーブン メネン，
ロバート アール． ミルバーン，
ロバート アール． ミルバーン，
ジェイソン テッドロウ，
ジェイソン テッドロウ，
ババック リアヒ，
ババック リアヒ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
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Amgen Inc
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Publication date
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Publication of JP2015517531A publication Critical patent/JP2015517531A/ja
Publication of JP2015517531A5 publication Critical patent/JP2015517531A5/ja
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Publication of JP6177894B2 publication Critical patent/JP6177894B2/ja
Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
JP2015512873A 2012-05-18 2013-05-17 チアジアゾールの調製方法 Expired - Fee Related JP6177894B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648928P 2012-05-18 2012-05-18
US61/648,928 2012-05-18
PCT/US2013/041504 WO2013173672A1 (en) 2012-05-18 2013-05-17 Method for the preparation of thiadiazoles

Publications (3)

Publication Number Publication Date
JP2015517531A JP2015517531A (ja) 2015-06-22
JP2015517531A5 JP2015517531A5 (enEXAMPLES) 2016-06-30
JP6177894B2 true JP6177894B2 (ja) 2017-08-09

Family

ID=49584318

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015512873A Expired - Fee Related JP6177894B2 (ja) 2012-05-18 2013-05-17 チアジアゾールの調製方法

Country Status (7)

Country Link
US (2) US9296735B2 (enEXAMPLES)
EP (1) EP2850057A4 (enEXAMPLES)
JP (1) JP6177894B2 (enEXAMPLES)
CN (1) CN104736518B (enEXAMPLES)
CA (1) CA2877026A1 (enEXAMPLES)
IN (1) IN2014KN02683A (enEXAMPLES)
WO (1) WO2013173672A1 (enEXAMPLES)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104788419B (zh) * 2014-12-30 2018-12-21 西华大学 手性（2，2-二甲基-1，3二氧环戊烷-4-基）羟基甲磺酸盐及其制备方法和应用
JP7560460B2 (ja) 2018-12-20 2024-10-02 バイエル、アクチエンゲゼルシャフト 殺真菌化合物としてのヘテロシクリルピリダジン
EP4167740A1 (en) 2020-06-18 2023-04-26 Bayer Aktiengesellschaft Active compound combinations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2544562A (en) * 1947-07-18 1951-03-06 Stanolind Oil & Gas Co Process for recovering aldehydes and ketones
DK36784A (da) 1983-02-25 1984-08-26 Hoffmann La Roche Fremgangsmaade til fremstilling af chirale aldehyder
DE19847823A1 (de) * 1998-10-16 2000-04-20 Aventis Pharma Gmbh Substituierte Thiadiazolsulfonamide
JP4144978B2 (ja) 1999-09-09 2008-09-03 富士フイルム株式会社 １，２，４−チアジアゾール誘導体の合成法
US8933077B2 (en) 2005-11-01 2015-01-13 Array Biopharma Inc. Glucokinase activators
ATE539748T1 (de) 2006-01-27 2012-01-15 Array Biopharma Inc Glucokinaseaktivatoren
TWI393718B (zh) 2006-03-24 2013-04-21 Array Biopharma Inc 葡萄糖激酶活化劑
US8431713B2 (en) 2007-01-24 2013-04-30 Array Biopharma, Inc. 2-aminopyridine derivatives as glucokinase activators
WO2008118718A2 (en) 2007-03-23 2008-10-02 Array Biopharma Inc. 2-aminopyridine analogs as glucokinase activators
US8212045B2 (en) * 2007-09-21 2012-07-03 Array Biopharma, Inc. Pyridin-2-yl-amino-1, 2, 4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
CN101671267B (zh) * 2009-09-30 2012-09-05 浙江理工大学 一种直接将醛或脂肪族甲基酮的亚硫酸氢钠加成产物转变为相应肟的方法

Also Published As

Publication number Publication date
US9296735B2 (en) 2016-03-29
CN104736518A (zh) 2015-06-24
IN2014KN02683A (enEXAMPLES) 2015-05-08
US20150141655A1 (en) 2015-05-21
EP2850057A4 (en) 2016-01-27
CN104736518B (zh) 2017-10-13
JP2015517531A (ja) 2015-06-22
US20160221985A1 (en) 2016-08-04
CA2877026A1 (en) 2013-11-21
WO2013173672A1 (en) 2013-11-21
EP2850057A1 (en) 2015-03-25

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