JP6173352B2 - 筋萎縮性側索硬化症の治療方法 - Google Patents
筋萎縮性側索硬化症の治療方法 Download PDFInfo
- Publication number
- JP6173352B2 JP6173352B2 JP2014557799A JP2014557799A JP6173352B2 JP 6173352 B2 JP6173352 B2 JP 6173352B2 JP 2014557799 A JP2014557799 A JP 2014557799A JP 2014557799 A JP2014557799 A JP 2014557799A JP 6173352 B2 JP6173352 B2 JP 6173352B2
- Authority
- JP
- Japan
- Prior art keywords
- als
- compound
- composition
- acid
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261599096P | 2012-02-15 | 2012-02-15 | |
| US61/599,096 | 2012-02-15 | ||
| PCT/US2013/026284 WO2013123290A1 (en) | 2012-02-15 | 2013-02-15 | Methods of treating amyotrophic lateral sclerosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015510517A JP2015510517A (ja) | 2015-04-09 |
| JP2015510517A5 JP2015510517A5 (enExample) | 2016-03-24 |
| JP6173352B2 true JP6173352B2 (ja) | 2017-08-02 |
Family
ID=48984729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014557799A Expired - Fee Related JP6173352B2 (ja) | 2012-02-15 | 2013-02-15 | 筋萎縮性側索硬化症の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9340483B2 (enExample) |
| EP (1) | EP2814479B1 (enExample) |
| JP (1) | JP6173352B2 (enExample) |
| CA (1) | CA2864797C (enExample) |
| WO (1) | WO2013123290A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3050572A1 (en) * | 2017-01-18 | 2018-07-26 | Universitat Autonoma De Barcelona | Specialized pro-resolving lipid mediators for use in the treatment of neurodegenerative diseases and/or autoimmune diseases |
| WO2019016580A1 (en) | 2017-07-20 | 2019-01-24 | Universitat Autonoma De Barcelona | MARESINS FOR USE IN THE TREATMENT OF CNS INJURIES |
| US10322114B2 (en) | 2017-07-31 | 2019-06-18 | Above And Beyond Nb, Llc | Formulation of a riluzole solution with beta-cyclodextrins |
| US20250381161A1 (en) * | 2022-06-21 | 2025-12-18 | Anida Pharma Inc. | Compositions and methods for treating hearing and ocular disorders |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1202068C (zh) | 2000-02-16 | 2005-05-18 | 布里格姆及妇女医院股份有限公司 | 阿司匹林触发的脂质介体 |
| AU2002343609B2 (en) * | 2001-11-16 | 2008-12-11 | Als Therapy Development Foundation, Inc. | Treatment of neurodegenerative disorders through the modulation of the polyamine pathway |
| US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
| WO2004093802A2 (en) * | 2003-04-17 | 2004-11-04 | The Board Of Trustees Of The Leland Stanford Junior University | Prevention of deficits in neurogenesis with anti-inflammatory agents |
| EP1660069A4 (en) * | 2003-08-05 | 2009-03-18 | Univ Louisiana State | NEUROPROTECTION AGAINST CELL APOPTOSIS, NEURAL STROKES, ALZHEIMER DISEASE AND RETINAL DEGENERATION |
| DK1691814T3 (da) * | 2003-12-01 | 2012-10-29 | Cambridge Entpr Ltd | Antiinflammatoriske midler |
| WO2007041440A2 (en) * | 2005-10-03 | 2007-04-12 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin d1/protectin d1 and its natural stereoisomers |
| US20110190389A1 (en) | 2007-02-20 | 2011-08-04 | Linda Arterburn | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
| WO2009018333A2 (en) | 2007-07-30 | 2009-02-05 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Dha and pedf, a therapeutic composition for nerve and retinal pigment epithelial cells |
| GB2452696B (en) * | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| US20090137527A1 (en) | 2007-09-14 | 2009-05-28 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for modulating immune function |
| WO2009056983A1 (en) | 2007-10-31 | 2009-05-07 | Pronova Biopharma Norge As | New dha derivatives and their use as medicaments |
| US7782152B2 (en) | 2008-08-14 | 2010-08-24 | Broadcom Corporation | Monotonic frequency tuning technique for DCXO in cellular applications |
| US20120122816A1 (en) | 2009-02-05 | 2012-05-17 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for organ preservation |
| US9468620B2 (en) * | 2013-02-28 | 2016-10-18 | Andida Pharma, Inc. | Methods of treating ototoxicity |
-
2013
- 2013-02-15 JP JP2014557799A patent/JP6173352B2/ja not_active Expired - Fee Related
- 2013-02-15 US US14/379,177 patent/US9340483B2/en active Active
- 2013-02-15 CA CA2864797A patent/CA2864797C/en active Active
- 2013-02-15 WO PCT/US2013/026284 patent/WO2013123290A1/en not_active Ceased
- 2013-02-15 EP EP13748858.1A patent/EP2814479B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2864797C (en) | 2022-03-22 |
| WO2013123290A1 (en) | 2013-08-22 |
| CA2864797A1 (en) | 2013-08-22 |
| EP2814479A1 (en) | 2014-12-24 |
| EP2814479A4 (en) | 2015-07-01 |
| US9340483B2 (en) | 2016-05-17 |
| JP2015510517A (ja) | 2015-04-09 |
| US20150010549A1 (en) | 2015-01-08 |
| WO2013123290A9 (en) | 2014-09-12 |
| EP2814479B1 (en) | 2019-09-04 |
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