JP6138173B2 - 実験室試料処理システムにおける動流体内の温度を制御するための方法及び装置 - Google Patents

実験室試料処理システムにおける動流体内の温度を制御するための方法及び装置 Download PDF

Info

Publication number
JP6138173B2
JP6138173B2 JP2014561131A JP2014561131A JP6138173B2 JP 6138173 B2 JP6138173 B2 JP 6138173B2 JP 2014561131 A JP2014561131 A JP 2014561131A JP 2014561131 A JP2014561131 A JP 2014561131A JP 6138173 B2 JP6138173 B2 JP 6138173B2
Authority
JP
Japan
Prior art keywords
fluid
temperature
well
housing
controller
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2014561131A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015509610A (ja
JP2015509610A5 (enExample
Inventor
サリヴァン，ケヴィン，ジェイ
ケランド，ジェイムス
グェン，ナト，カイ，エル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leica Biosystems Richmond Inc
Original Assignee
Leica Biosystems Richmond Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leica Biosystems Richmond Inc filed Critical Leica Biosystems Richmond Inc
Publication of JP2015509610A publication Critical patent/JP2015509610A/ja
Publication of JP2015509610A5 publication Critical patent/JP2015509610A5/ja
Application granted granted Critical
Publication of JP6138173B2 publication Critical patent/JP6138173B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/23—Mixing the contents of independent containers, e.g. test tubes by pivoting the containers about an axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/211—Measuring of the operational parameters
    • B01F35/2115—Temperature
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
    • B01F35/2215—Temperature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00—Control of temperature
    • G05D23/19—Control of temperature characterised by the use of electric means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00386—Holding samples at elevated temperature (incubation) using fluid heat transfer medium
    • G01N2035/00396—Holding samples at elevated temperature (incubation) using fluid heat transfer medium where the fluid is a liquid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/112499—Automated chemical analysis with sample on test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/115831—Condition or time responsive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Automation & Control Theory (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2014561131A 2012-03-09 2013-03-08 実験室試料処理システムにおける動流体内の温度を制御するための方法及び装置 Expired - Fee Related JP6138173B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261608762P 2012-03-09 2012-03-09
US61/608,762 2012-03-09
PCT/US2013/029747 WO2013134583A1 (en) 2012-03-09 2013-03-08 Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system

Publications (3)

Publication Number Publication Date
JP2015509610A JP2015509610A (ja) 2015-03-30
JP2015509610A5 JP2015509610A5 (enExample) 2016-04-14
JP6138173B2 true JP6138173B2 (ja) 2017-05-31

Family

ID=49117367

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014561131A Expired - Fee Related JP6138173B2 (ja) 2012-03-09 2013-03-08 実験室試料処理システムにおける動流体内の温度を制御するための方法及び装置

Country Status (6)

Country Link
US (1) US9909962B2 (enExample)
EP (1) EP2823281B1 (enExample)
JP (1) JP6138173B2 (enExample)
CN (1) CN104272082B (enExample)
CA (1) CA2866854C (enExample)
WO (1) WO2013134583A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6397674B2 (ja) * 2014-07-18 2018-09-26 株式会社日立ハイテクノロジーズ 自動分析装置
BR112017019455A2 (pt) 2015-03-19 2018-05-15 Beckman Coulter Inc dispensador para um analisador
KR102134953B1 (ko) 2015-05-29 2020-07-16 일루미나, 인코포레이티드 지정된 반응을 수행하기 위한 샘플 캐리어 및 검정 시스템
DE102016225885B4 (de) * 2016-12-21 2023-12-21 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischem Material
AU2018262829A1 (en) * 2017-05-04 2019-12-05 Ntnu - Norges Teknisk-Naturvitenskapelige Universitet Cell culture device
CN110271691B (zh) * 2019-07-05 2022-11-22 中国飞机强度研究所 飞机气候环境实验室温度校准布局结构、采集系统及方法
DE102019215577B3 (de) * 2019-10-10 2020-11-05 Prime23 GmbH Vorrichtung und Verfahren zur Benetzung von biologischem Material
AU2021281387B2 (en) * 2020-05-27 2026-03-12 Agilent Technologies, Inc. Apparatus and method for processing biological samples
CN113134318B (zh) * 2021-03-18 2023-02-03 上海品致测控技术有限公司 恒温摇床控制方法及控制器

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3226094A (en) * 1963-08-01 1965-12-28 Royal Alexandra Hosp Children Warming and shaking apparatus
US5104621A (en) 1986-03-26 1992-04-14 Beckman Instruments, Inc. Automated multi-purpose analytical chemistry processing center and laboratory work station
EP0342155A3 (de) 1988-05-13 1990-06-27 Agrogen-Stiftung Laboratoriumsgerät zum wahlweisen Heizen und Kühlen
AU5247790A (en) * 1989-04-20 1990-10-25 Biotrack, Inc. Capillary flow device and reading instrument
AU635008B2 (en) 1989-12-13 1993-03-11 Genelabs Diagnostics Pte Ltd Analytical apparatus and method for automated blot assay
US5355304A (en) 1990-01-30 1994-10-11 Demoranville Victoria E Clinical laboratory work-flow system which semi-automates validated immunoassay and electrophoresis protocols
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
ATE154981T1 (de) 1990-04-06 1997-07-15 Perkin Elmer Corp Automatisiertes labor für molekularbiologie
US5167615A (en) 1990-05-15 1992-12-01 Pudenz-Schulte Medical Research Corporation Flow control device having selectable alternative fluid pathways
US6180061B1 (en) 1992-05-11 2001-01-30 Cytologix Corporation Moving platform slide stainer with heating elements
JP3491948B2 (ja) 1993-03-05 2004-02-03 ウォーターズ・インベストメンツ・リミテッド 溶剤ポンプ送り装置
ATE282195T1 (de) 1993-08-16 2004-11-15 Bio Merieux Inc Methode und gerät zur automatischen durchführung von analysen bezüglich thrombose und blutgerinnung
CA2146177C (en) 1995-04-03 2000-09-05 Adrian P. Wade Intelligent flow analysis network
US5625706A (en) 1995-05-31 1997-04-29 Neopath, Inc. Method and apparatus for continously monitoring and forecasting slide and specimen preparation for a biological specimen population
US5674006A (en) * 1996-03-27 1997-10-07 Hoefer Pharmacia Biotech, Inc. Fluid circulation apparatus
US5897781A (en) 1997-06-06 1999-04-27 Waters Investments Limited Active pump phasing to enhance chromatographic reproducibility
US6793890B2 (en) 1997-08-20 2004-09-21 The University Of Miami Rapid tissue processor
EP1073892B1 (en) 1998-02-27 2010-11-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
CA2339163C (en) 1998-08-10 2010-01-12 Genomic Solutions, Inc. Thermal and fluidic cycling device for nucleic acid hybridization
US5993654A (en) 1998-09-24 1999-11-30 Eldex Laboratories, Inc. Pressurized liquid delivery apparatus
US6637463B1 (en) 1998-10-13 2003-10-28 Biomicro Systems, Inc. Multi-channel microfluidic system design with balanced fluid flow distribution
US6212705B1 (en) 1998-11-06 2001-04-10 Daniel J. Kramer Bathtub tray with drain
US7510841B2 (en) 1998-12-28 2009-03-31 Illumina, Inc. Methods of making and using composite arrays for the detection of a plurality of target analytes
US6225061B1 (en) 1999-03-10 2001-05-01 Sequenom, Inc. Systems and methods for performing reactions in an unsealed environment
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
US7056477B1 (en) 2000-02-03 2006-06-06 Cellular Process Chemistry, Inc. Modular chemical production system incorporating a microreactor
AU4536501A (en) 2000-02-29 2001-09-12 Gen Probe Inc Fluid dispense and fluid surface verification system and method
AU2001259770A1 (en) 2000-05-15 2001-11-26 Biomicro Systems, Inc. Air flow regulation in microfluidic circuits for pressure control and gaseous exchange
US6615856B2 (en) 2000-08-04 2003-09-09 Biomicro Systems, Inc. Remote valving for microfluidic flow control
AU2002213345A1 (en) 2000-10-13 2002-04-22 Irm, Llc High throughput processing system and method of using
JP2004537712A (ja) 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
WO2002072264A1 (en) 2001-03-09 2002-09-19 Biomicro Systems, Inc. Method and system for microfluidic interfacing to arrays
US6881579B2 (en) 2001-07-30 2005-04-19 Agilent Technologies, Inc. Sample processing apparatus and methods
GB0124613D0 (en) 2001-10-12 2001-12-05 Alpha Thames Ltd System and method for separating fluids
CN1325126C (zh) 2001-11-16 2007-07-11 梅德创新股份公司 医药用的泵装置
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
PT1501398E (pt) * 2002-05-06 2007-01-31 Gruppo Cimbali Spa Dispositivo para aquecer e emulsionar leite
US20050239195A1 (en) * 2002-06-13 2005-10-27 Millenium Biologix Ag Reaction chamber
JP4075656B2 (ja) * 2003-03-25 2008-04-16 日立工機株式会社 インキュベータ及び、インキュベータを備えた分注機
TW579430B (en) 2003-05-02 2004-03-11 Dr Chip Biotechnology Inc Automatic micro-fluid hybridization chip platform
US7361315B2 (en) 2004-10-26 2008-04-22 Konica Minolta Medical & Graphic, Inc. Micro-reactor for biological substance inspection and biological substance inspection device
US20060141635A1 (en) 2004-12-28 2006-06-29 Shimadzu Corporation Method and apparatus for preprocessing sample according to form by hydride introduction method
US7794659B2 (en) * 2005-03-10 2010-09-14 Gen-Probe Incorporated Signal measuring system having a movable signal measuring device
JP5063616B2 (ja) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド マイクロ流体デバイス
WO2007092571A2 (en) * 2006-02-07 2007-08-16 Wafergen, Inc. Temperature-regulated culture plates
US20100200021A1 (en) 2006-02-17 2010-08-12 Nils Adey Slide Conditioning Systems and Methods
WO2007122814A1 (ja) * 2006-04-13 2007-11-01 Research Organization Of Information And Systems マルチウェルインキュベーション装置及びこれを用いた分析方法
US8232091B2 (en) * 2006-05-17 2012-07-31 California Institute Of Technology Thermal cycling system
US7985375B2 (en) 2007-04-06 2011-07-26 Qiagen Gaithersburg, Inc. Sample preparation system and method for processing clinical specimens
US7811522B2 (en) 2007-07-05 2010-10-12 Viaflo Corporation Sample reservoir kits with disposable liners
JP2011007496A (ja) 2007-09-14 2011-01-13 Nec Corp 分析装置
US20100167943A1 (en) 2008-06-09 2010-07-01 Nils Adey System and Method for Hybridization Slide Processing
US8975039B2 (en) 2008-06-09 2015-03-10 SYFR, Inc. Automatic sample staining method
JP2010048695A (ja) * 2008-08-22 2010-03-04 Olympus Corp 自動分析装置および恒温槽安定化方法
EP2350673B1 (en) 2008-10-24 2022-05-11 Leica Biosystems Richmond, Inc. Modular system for performing laboratory protocols and associated methods
WO2010132756A2 (en) 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
EP2564206A4 (en) 2010-04-29 2016-09-07 Leica Biosystems Richmond Inc ANALYSIS SYSTEM FOR CARRYING OUT LABORATORY PROTOCOLS AND RELATED METHODS

Also Published As

Publication number Publication date
WO2013134583A1 (en) 2013-09-12
CA2866854A1 (en) 2013-09-12
JP2015509610A (ja) 2015-03-30
EP2823281A4 (en) 2015-07-01
EP2823281B1 (en) 2018-11-28
EP2823281A1 (en) 2015-01-14
US9909962B2 (en) 2018-03-06
CN104272082B (zh) 2017-02-22
CA2866854C (en) 2020-08-18
US20150044664A1 (en) 2015-02-12
CN104272082A (zh) 2015-01-07

Similar Documents

Publication Publication Date Title
JP2015509610A (ja) 実験室試料処理システムにおける動流体内の温度を制御するための方法及び装置
JP4494405B2 (ja) 試料処理システム
US8968675B2 (en) Sample processing system
CN109562384B (zh) 用于样品分析与处理的快速热循环
CN113801784B (zh) 核酸加载装置及用途
EP2350673B1 (en) Modular system for performing laboratory protocols and associated methods
JP2020519430A (ja) 生体試料の急速加熱のための方法および装置
EP4263058A1 (en) System for controlling the temperature of a microfluidic chip and a microfluidic apparatus for monitoring a substance in a microfluidic chip including such system
CN110612450A (zh) 实验室仪器、实验室仪器网络和用于对实验室样品进行工作的方法
JP5921336B2 (ja) 自動分析装置及び前処理装置
CN110662968A (zh) 实验室仪器和可插入网络仪器
HK1247634B (en) Carrying module, nucleic acid loading device and use thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141111

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160222

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160222

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20161221

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170110

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170404

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20170418

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170425

R150 Certificate of patent or registration of utility model

Ref document number: 6138173

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees