JP6134735B2 - Ans刺激 - Google Patents
Ans刺激 Download PDFInfo
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- JP6134735B2 JP6134735B2 JP2014546554A JP2014546554A JP6134735B2 JP 6134735 B2 JP6134735 B2 JP 6134735B2 JP 2014546554 A JP2014546554 A JP 2014546554A JP 2014546554 A JP2014546554 A JP 2014546554A JP 6134735 B2 JP6134735 B2 JP 6134735B2
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H1/00—Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/04—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with hydraulic or pneumatic drive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/50—Control means thereof
- A61H2201/5023—Interfaces to the user
- A61H2201/5043—Displays
- A61H2201/5046—Touch screens
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Percussion Or Vibration Massage (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161576832P | 2011-12-16 | 2011-12-16 | |
| US61/576,832 | 2011-12-16 | ||
| PCT/EP2012/075653 WO2013087895A1 (en) | 2011-12-16 | 2012-12-14 | Ans stimulation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015500114A JP2015500114A (ja) | 2015-01-05 |
| JP2015500114A5 JP2015500114A5 (enExample) | 2016-01-28 |
| JP6134735B2 true JP6134735B2 (ja) | 2017-05-24 |
Family
ID=47504904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014546554A Active JP6134735B2 (ja) | 2011-12-16 | 2012-12-14 | Ans刺激 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9486381B2 (enExample) |
| EP (1) | EP2790635B1 (enExample) |
| JP (1) | JP6134735B2 (enExample) |
| CN (1) | CN104144670B (enExample) |
| WO (1) | WO2013087895A1 (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
| US20200315541A1 (en) * | 2012-02-16 | 2020-10-08 | Vibrant Ltd. | Gastrointestinal Capsule and Treatment Method |
| US10220169B2 (en) * | 2012-12-21 | 2019-03-05 | Zoll Medical Corporation | Ventilation monitoring |
| WO2014165124A1 (en) | 2013-03-12 | 2014-10-09 | Oculeve, Inc. | Implant delivery devices, systems, and methods |
| NZ745920A (en) | 2013-04-19 | 2020-01-31 | Oculeve Inc | Nasal stimulation devices and methods |
| NL1040380C2 (en) * | 2013-09-07 | 2015-03-10 | Anthonius Fredericus Maria Bende | Face masks and software/application for activating no production in sinuses. |
| KR102264562B1 (ko) * | 2013-09-19 | 2021-06-11 | 칠드런스 내셔널 메디컬 센터 | 환자의 생리적 동요를 결정하기 위한 장치 및 방법 |
| US9770583B2 (en) | 2014-02-25 | 2017-09-26 | Oculeve, Inc. | Polymer formulations for nasolacrimal stimulation |
| JP6358532B2 (ja) * | 2014-03-13 | 2018-07-18 | パナソニックIpマネジメント株式会社 | マッサージ計測装置およびマッサージ計測方法 |
| US9687652B2 (en) | 2014-07-25 | 2017-06-27 | Oculeve, Inc. | Stimulation patterns for treating dry eye |
| US9764150B2 (en) | 2014-10-22 | 2017-09-19 | Oculeve, Inc. | Contact lens for increasing tear production |
| EP3209371A4 (en) | 2014-10-22 | 2018-10-24 | Oculeve, Inc. | Implantable nasal stimulator systems and methods |
| JP6735742B2 (ja) | 2014-10-22 | 2020-08-05 | オキュリーブ, インコーポレイテッド | ドライアイの治療のための刺激装置及び方法 |
| DE102015101823A1 (de) | 2015-02-09 | 2016-08-11 | Forschungszentrum Jülich GmbH | Vorrichtung und Verfahren zur Kalibrierung einer nicht-invasiven mechanisch taktilen und/oder thermischen Neurostimulation |
| US20180146839A1 (en) | 2015-06-24 | 2018-05-31 | The Regents Of The University Of Colorado, A Body Corporate | Multi-use scope |
| US11717140B2 (en) | 2015-06-24 | 2023-08-08 | The Regents Of The University Of Colorado, A Body Corporate | Multi-use endoscope with integrated device-patient monitoring and patient-provider positioning and disassociation system |
| US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
| US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
| CA3022683A1 (en) | 2016-05-02 | 2017-11-09 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
| CN106344295B (zh) * | 2016-08-13 | 2018-11-02 | 于华 | 心内科防衰护理台 |
| US11305077B2 (en) | 2016-09-14 | 2022-04-19 | Healthy Humming, LLC | Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat |
| WO2018053079A1 (en) | 2016-09-14 | 2018-03-22 | Bogan Consulting Services, P.A. | Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat |
| US11213641B2 (en) | 2016-09-14 | 2022-01-04 | Healthy Humming, LLC | Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat |
| US11432993B2 (en) | 2016-09-14 | 2022-09-06 | Healthy Humming, LLC | Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat |
| US11504024B2 (en) | 2018-03-30 | 2022-11-22 | Vibrant Ltd. | Gastrointestinal treatment system including a vibrating capsule, and method of use thereof |
| GB2554354B (en) | 2016-09-21 | 2021-06-02 | Vibrant Ltd | Systems for adaptive treatment of disorders in the gastrointestinal tract |
| US12233017B2 (en) | 2016-10-14 | 2025-02-25 | Olympic Ophthalmics, Inc. | Quiet handheld devices and methods for treatment of disorders |
| US20180133102A1 (en) * | 2016-11-14 | 2018-05-17 | Otolith Sound, Inc. | Devices And Methods For Reducing The Symptoms Of Maladies Of The Vestibular System |
| WO2018102535A1 (en) | 2016-12-02 | 2018-06-07 | Oculeve, Inc. | Apparatus and method for dry eye forecast and treatment recommendation |
| FR3060398B1 (fr) * | 2016-12-15 | 2019-07-19 | Aptar France Sas | Ensemble de distribution nasale de produit fluide. |
| US10905378B1 (en) * | 2017-01-30 | 2021-02-02 | Vibrant Ltd | Method for treating gastroparesis using a vibrating ingestible capsule |
| US10888277B1 (en) * | 2017-01-30 | 2021-01-12 | Vibrant Ltd | Method for treating diarrhea and reducing Bristol stool scores using a vibrating ingestible capsule |
| ES2949397T3 (es) | 2017-03-28 | 2023-09-28 | Abilion Medical Systems Ab | Sistema para la estimulación mecánica de tejidos |
| EP3684463B1 (en) | 2017-09-19 | 2025-05-14 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement |
| US11717686B2 (en) | 2017-12-04 | 2023-08-08 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to facilitate learning and performance |
| US11478603B2 (en) | 2017-12-31 | 2022-10-25 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to enhance emotional response |
| US12280219B2 (en) | 2017-12-31 | 2025-04-22 | NeuroLight, Inc. | Method and apparatus for neuroenhancement to enhance emotional response |
| WO2019152135A1 (en) | 2018-01-30 | 2019-08-08 | Apex Neuro Inc. | Devices and methods for delivering mechanical stimulation to nerve, mechanoreceptor, and cell targets |
| US11147735B2 (en) | 2018-02-26 | 2021-10-19 | Olympic Ophthalmics, Inc. | Therapeutic handheld devices for disorders |
| US11638678B1 (en) | 2018-04-09 | 2023-05-02 | Vibrant Ltd. | Vibrating capsule system and treatment method |
| US12083303B2 (en) | 2019-01-21 | 2024-09-10 | Vibrant Ltd. | Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user |
| US11364361B2 (en) | 2018-04-20 | 2022-06-21 | Neuroenhancement Lab, LLC | System and method for inducing sleep by transplanting mental states |
| CA3098298A1 (en) * | 2018-04-25 | 2020-01-30 | Jean Philippe GIACOMINI | Stimulation device and method of use |
| US11510590B1 (en) | 2018-05-07 | 2022-11-29 | Vibrant Ltd. | Methods and systems for treating gastrointestinal disorders |
| US10974079B2 (en) | 2018-08-29 | 2021-04-13 | General Electric Company | Neuromodulation techniques |
| US20210186801A1 (en) * | 2018-09-05 | 2021-06-24 | University Of Miami | Personalized device to automatically detect and reduce muscle spasms with vibration |
| US11452839B2 (en) | 2018-09-14 | 2022-09-27 | Neuroenhancement Lab, LLC | System and method of improving sleep |
| CN113164024A (zh) * | 2018-09-17 | 2021-07-23 | 科罗拉多州立大学董事会(法人团体) | 装置-患者监测与患者-提供者定位集成式多用途内窥镜以及解除关联系统 |
| US12115330B2 (en) | 2019-01-03 | 2024-10-15 | Vibrant Ltd. | Device and method for delivering an ingestible medicament into the gastrointestinal tract of a user |
| US11607275B2 (en) * | 2019-05-20 | 2023-03-21 | Medtronic Ireland Manufacturing Unlimited Company | Selection of hypertensive patients for treatment with renal denervation |
| US11786694B2 (en) | 2019-05-24 | 2023-10-17 | NeuroLight, Inc. | Device, method, and app for facilitating sleep |
| CN111358682A (zh) * | 2020-03-17 | 2020-07-03 | 成都医学院第一附属医院 | 一种早产儿口腔按摩器 |
| USD1071216S1 (en) | 2021-08-31 | 2025-04-15 | Evoendo, Inc. | Handle assembly |
| USD1046119S1 (en) | 2021-08-31 | 2024-10-08 | Evoendo, Inc. | Endoscope distal end |
| USD1047142S1 (en) | 2021-08-31 | 2024-10-15 | Evoendo, Inc. | Endoscope |
| WO2025244038A1 (ja) * | 2024-05-21 | 2025-11-27 | 学校法人 聖マリアンナ医科大学 | 振動刺激装置、振動刺激器具、及び治療方法 |
| CN118319717B (zh) * | 2024-06-14 | 2024-09-27 | 浙江强脑科技有限公司 | 基于振动胶囊的刺激胃部迷走神经的控制方法及装置 |
| CN120477714A (zh) * | 2025-06-03 | 2025-08-15 | 中国人民解放军总医院第四医学中心 | 一种骨关节炎康复辅助装置及系统 |
Family Cites Families (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US901376A (en) | 1907-09-06 | 1908-10-20 | Harvey H Roberts | Massage and vibratory dilator. |
| US912205A (en) | 1908-06-09 | 1909-02-09 | Solox Chemical Company | Apparatus for applying internal massage. |
| US961034A (en) | 1909-09-02 | 1910-06-07 | Siebert Welch Company | Massage apparatus. |
| FR592104A (fr) | 1924-03-20 | 1925-07-28 | Préparateur dilatateur périnéal | |
| US1735519A (en) | 1926-07-17 | 1929-11-12 | Arlyn T Vance | Physician's dilator |
| US1764838A (en) | 1928-11-03 | 1930-06-17 | Newton H Horne | Hydraulic pulsator |
| GB385992A (en) | 1931-07-04 | 1933-01-04 | Georges Klass | A device to relieve and soothe nervous headache and insomnia |
| US2052321A (en) | 1934-07-25 | 1936-08-25 | Smart Harry Vincent | Treatment of sinuses |
| US2101273A (en) | 1935-01-09 | 1937-12-07 | Wallace D Smith | Massage instrument for treating the prostate gland |
| FR838034A (fr) | 1938-05-16 | 1939-02-24 | Perfectionnements apportés aux dispositifs pour le traitement du grand sympathique à l'aide de touches nasales | |
| FR920885A (fr) | 1945-10-22 | 1947-04-21 | Appareil éducateur et contrôleur de muscles organiques | |
| CH329193A (de) | 1954-07-24 | 1958-04-15 | Maurice Dr Med Fuchs | Massagevorrichtung |
| US3055371A (en) * | 1958-12-23 | 1962-09-25 | Kulick George | Device for regulation and control of esophago-gastric balloons |
| US3209755A (en) * | 1961-02-03 | 1965-10-05 | Avco Corp | Nasal catheter holder |
| US3496932A (en) | 1967-12-22 | 1970-02-24 | Gen Motors Corp | Method and apparatus for substernal cardiac massage |
| US3612211A (en) | 1969-07-02 | 1971-10-12 | William T Clark | Method of producing locally occurring infrasound |
| US3848607A (en) | 1971-10-29 | 1974-11-19 | M Clair | Therapeutic apparatus |
| US4343303A (en) * | 1980-10-21 | 1982-08-10 | Williams L Benton | Stimulating apparatus |
| US4373523A (en) * | 1980-10-23 | 1983-02-15 | Treutelaar Edward J | Helmet mounted constant tension traction device |
| US4462411A (en) | 1981-01-07 | 1984-07-31 | The University Of Melbourne | Evoked response audiometer |
| SU1148614A1 (ru) | 1982-03-25 | 1985-04-07 | Пензенский государственный институт усовершенствования врачей | Способ лечени хронического атрофического ринита |
| US4593688A (en) * | 1984-05-30 | 1986-06-10 | Payton Hugh W | Apparatus for the delivery of oxygen or the like |
| US4911149A (en) | 1984-06-18 | 1990-03-27 | Urological Instruments Research, Inc. | Vibratory treatment method and apparatus |
| SE8404375D0 (sv) * | 1984-08-31 | 1984-08-31 | Jerzy Antowski | Behandlingsapparat for menieer-sjukdom |
| SU1560205A1 (ru) | 1987-04-27 | 1990-04-30 | Пензенский государственный институт усовершенствования врачей | Устройство дл внутриносового вибромассажа |
| US5139510A (en) | 1991-02-22 | 1992-08-18 | Xomed-Treace Inc. | Nasal packing device |
| RU2099039C1 (ru) | 1992-03-13 | 1997-12-20 | Зеленкин Евгений Михайлович | Способ лечения нейровегетативной формы вазомоторного ринита |
| DE69417465T2 (de) | 1993-02-05 | 1999-07-22 | The Joe W. And Dorothy Dorsett Brown Foundation, New Orleans | Ultraschallballonkatheter für Angioplastik |
| DE29508077U1 (de) | 1995-05-16 | 1995-08-10 | Wilden Lutz Dr Med | Mundpflegegerät |
| AU5873496A (en) | 1995-06-06 | 1996-12-24 | Gregory A. Hogle | Inflatable nasal packing device |
| US5903516A (en) | 1996-05-08 | 1999-05-11 | Mayo Foundation For Medical Education And Research | Acoustic force generator for detection, imaging and information transmission using the beat signal of multiple intersecting sonic beams |
| AU3404597A (en) | 1996-06-18 | 1998-01-07 | William R. Parsons | Intrathoracic cardiac compression |
| USRE39539E1 (en) * | 1996-08-19 | 2007-04-03 | Torch William C | System and method for monitoring eye movement |
| US5846218A (en) | 1996-09-05 | 1998-12-08 | Pharmasonics, Inc. | Balloon catheters having ultrasonically driven interface surfaces and methods for their use |
| US5755225A (en) * | 1996-09-30 | 1998-05-26 | Hutson & Associates, Inc. | Medical tube-retaining device |
| US5682881A (en) | 1996-10-21 | 1997-11-04 | Winthrop; Neil | Nasal CPAP/Cannula and securement apparatus |
| US6159170A (en) | 1997-03-13 | 2000-12-12 | Borodulin; German | Universal mechanical dilator combined with massaging action |
| US6647296B2 (en) | 1997-10-27 | 2003-11-11 | Neuropace, Inc. | Implantable apparatus for treating neurological disorders |
| US20040230252A1 (en) | 1998-10-21 | 2004-11-18 | Saul Kullok | Method and apparatus for affecting the autonomic nervous system |
| US6748275B2 (en) | 1999-05-05 | 2004-06-08 | Respironics, Inc. | Vestibular stimulation system and method |
| JP2001017500A (ja) | 1999-07-07 | 2001-01-23 | Shintou Something:Kk | 鼻炎治療具 |
| JP2001037883A (ja) | 1999-07-27 | 2001-02-13 | Olympus Optical Co Ltd | ダイレータ |
| US20060095032A1 (en) | 1999-11-16 | 2006-05-04 | Jerome Jackson | Methods and systems for determining physiologic characteristics for treatment of the esophagus |
| WO2001041695A2 (en) | 1999-12-13 | 2001-06-14 | Theracardia, Inc. | Minimally-invasive direct cardiac massage apparatus and method |
| CA2408097A1 (en) * | 2000-05-08 | 2001-11-15 | Brainsgate Ltd. | Method and apparatus for stimulating the sphenopalatine ganglion to modify properties of the bbb and cerebral blood flow |
| EP1309304A2 (en) | 2000-07-14 | 2003-05-14 | Hill-Rom Services, Inc. | Pulmonary therapy apparatus |
| RU2199303C1 (ru) | 2001-06-19 | 2003-02-27 | Научно-клинический центр оториноларингологии | Способ вибротерапии нейровегетативной формы вазомоторного ринита |
| EP1418861A2 (en) | 2001-07-27 | 2004-05-19 | WIT IP Corporation | Methods for treating prostatitis |
| US6684883B1 (en) * | 2001-08-21 | 2004-02-03 | Bonnie C. Burns | Nasal cannula headband apparatus |
| US20030087734A1 (en) | 2001-11-02 | 2003-05-08 | Kring Robert S. | Vaginal-pelvic muscle exerciser and birthing trainer |
| US6878122B2 (en) * | 2002-01-29 | 2005-04-12 | Oregon Health & Science University | Method and device for rehabilitation of motor dysfunction |
| US20040049134A1 (en) * | 2002-07-02 | 2004-03-11 | Tosaya Carol A. | System and methods for treatment of alzheimer's and other deposition-related disorders of the brain |
| US8317816B2 (en) | 2002-09-30 | 2012-11-27 | Acclarent, Inc. | Balloon catheters and methods for treating paranasal sinuses |
| US7232417B2 (en) | 2002-11-13 | 2007-06-19 | Dymedso Inc. | Acoustic therapeutic device and method for treating cystic fibrosis and other respiratory pathologies |
| US7077812B2 (en) | 2002-11-22 | 2006-07-18 | The Board Regents Of The University System | Apparatus and method for palpographic characterization of vulnerable plaque and other biological tissue |
| US7108706B2 (en) * | 2003-05-28 | 2006-09-19 | Rose Biomedical Development Corporation | Inflatable nasal packing device with two non-elastic, flexible bags oversized relative to nasal cavities |
| US7149574B2 (en) | 2003-06-09 | 2006-12-12 | Palo Alto Investors | Treatment of conditions through electrical modulation of the autonomic nervous system |
| CA2439667A1 (en) | 2003-09-04 | 2005-03-04 | Andrew Kenneth Hoffmann | Low frequency vibration assisted blood perfusion system and apparatus |
| US9101384B2 (en) | 2004-04-21 | 2015-08-11 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat |
| US20050267388A1 (en) | 2004-05-26 | 2005-12-01 | Hanna Joseph P | Method and apparatus for relief of headache |
| EP1773439A4 (en) | 2004-07-14 | 2010-01-20 | By Pass Inc | MATERIAL DISTRIBUTION SYSTEM |
| US7711432B2 (en) * | 2004-07-26 | 2010-05-04 | Advanced Neuromodulation Systems, Inc. | Stimulation system and method for treating a neurological disorder |
| GB0421215D0 (en) | 2004-09-23 | 2004-10-27 | Procyon Instr Ltd | Pupillometers |
| WO2006050382A2 (en) | 2004-11-02 | 2006-05-11 | Jimmyjane, Inc. | Personal vibrator with replaceable motor |
| US7364573B2 (en) | 2004-11-30 | 2008-04-29 | Anthony Garabet | Method and apparatus for pressurizing a body cavity for diagnostic and rehabilitative purposes |
| EP1874384A4 (en) | 2005-04-28 | 2010-05-26 | By Pass Inc | MATERIAL ADMINISTRATION SYSTEM |
| US20080200848A1 (en) | 2005-06-02 | 2008-08-21 | Ads & B Investment Fund L.P | Vibrating Device For Treating Nasal Congestion and Sinusitis Symptoms and Method Thereof |
| US20100004709A1 (en) * | 2006-10-26 | 2010-01-07 | Hans Alois Mische | Physiologic stimulation for stroke treatment |
| US20090005713A1 (en) * | 2007-02-12 | 2009-01-01 | Podrazhansky Yury M | Method and Device for Using Vibroacoustical Stimulation to Treat Target Tissue Areas of Living Organisms |
| JP4572214B2 (ja) | 2007-05-09 | 2010-11-04 | 株式会社アクション・リサーチ | 振動呈示装置 |
| SE531172C2 (sv) * | 2007-05-16 | 2009-01-13 | Rhinomed Ab | Vibrationsanordning avsedd att användas i kroppskaviteter, företrädesvis i näshålan |
| US20100249637A1 (en) | 2008-05-08 | 2010-09-30 | Lotus Magnus, Llc | Systems, devices, and methods for treating restless leg syndrome and periodic limb movement disorder |
| WO2010033055A1 (en) | 2008-09-17 | 2010-03-25 | Handmedic Hb | A system for applying controlled selective vibration stimuli to the hand |
| JP2012505050A (ja) | 2008-10-10 | 2012-03-01 | インターバルブ, インコーポレイテッド | 弁形成術用カテーテルおよび方法 |
| EP3231365B1 (en) * | 2008-10-15 | 2025-01-22 | Nuvasive, Inc. | Neurophysiologic monitoring system |
| US8612010B2 (en) * | 2008-12-23 | 2013-12-17 | Robotic Integrated Technology Development Corporation | Upper extremity muscle therapy system |
| US9492680B2 (en) | 2009-03-06 | 2016-11-15 | Neuralieve | Method and apparatus to record and analyze TMS treatments and results |
| US20100286576A1 (en) | 2009-05-06 | 2010-11-11 | Bwt Property, Inc. | Photo Therapy and Massage Apparatus for Relieving Pain in Body Cavities |
| US8499762B2 (en) * | 2009-06-24 | 2013-08-06 | Ronald Richard Couts | Apparatus for alleviating pressure on ears while using oxygen |
| US20110190668A1 (en) | 2010-02-03 | 2011-08-04 | Mishelevich David J | Ultrasound neuromodulation of the sphenopalatine ganglion |
| US20110270138A1 (en) | 2010-05-02 | 2011-11-03 | Mishelevich David J | Ultrasound macro-pulse and micro-pulse shapes for neuromodulation |
| US9126044B2 (en) * | 2010-04-15 | 2015-09-08 | Cardiac Pacemakers, Inc. | Autonomic modulation using transient response with intermittent neural stimulation |
| KR101019957B1 (ko) | 2010-09-08 | 2011-03-09 | 박충식 | 휴대용 비염치료기 |
| US20120253236A1 (en) * | 2011-04-04 | 2012-10-04 | Snow Buddy L | Methods and apparatuses for delivering external therapeutic stimulation to animals and humans |
| US9004071B2 (en) * | 2011-10-18 | 2015-04-14 | Ian Joseph Alexander | Nasal guide and method of use thereof |
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| CN104144670B (zh) | 2016-10-19 |
| JP2015500114A (ja) | 2015-01-05 |
| EP2790635A1 (en) | 2014-10-22 |
| US20130158452A1 (en) | 2013-06-20 |
| WO2013087895A1 (en) | 2013-06-20 |
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