JP6083860B2 - Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療 - Google Patents

Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療 Download PDF

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JP6083860B2
JP6083860B2 JP2012511052A JP2012511052A JP6083860B2 JP 6083860 B2 JP6083860 B2 JP 6083860B2 JP 2012511052 A JP2012511052 A JP 2012511052A JP 2012511052 A JP2012511052 A JP 2012511052A JP 6083860 B2 JP6083860 B2 JP 6083860B2
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odc
patient
agent
ornithine decarboxylase
genotype
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JP2012526852A5 (enExample
JP2012526852A (ja
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ガーナー，ユージーン
ゼル，ジェイソン
マクラレン，クリスティン
メイスケンス，フランク
アントン−カルバー，ホダ
トンプソン，パトリシア，エー．
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University of Arizona
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Wood Science & Technology (AREA)
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  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012511052A 2009-05-14 2010-05-14 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療 Expired - Fee Related JP6083860B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US21621609P 2009-05-14 2009-05-14
US61/216,216 2009-05-14
US21768209P 2009-06-03 2009-06-03
US21767909P 2009-06-03 2009-06-03
US61/217,682 2009-06-03
US61/217,679 2009-06-03
PCT/US2010/034974 WO2010132817A1 (en) 2009-05-14 2010-05-14 Carcinoma diagnosis and treatments, based on odc1 genotype

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JP2015213116A Division JP2016074672A (ja) 2009-05-14 2015-10-29 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療

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JP2012526852A JP2012526852A (ja) 2012-11-01
JP2012526852A5 JP2012526852A5 (enExample) 2013-06-27
JP6083860B2 true JP6083860B2 (ja) 2017-02-22

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JP2015213116A Pending JP2016074672A (ja) 2009-05-14 2015-10-29 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療

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US (4) US8329636B2 (enExample)
EP (1) EP2430452B1 (enExample)
JP (2) JP6083860B2 (enExample)
CN (1) CN102483415B (enExample)
AU (1) AU2010248803B2 (enExample)
CA (1) CA2761946A1 (enExample)
DK (1) DK2430452T3 (enExample)
ES (1) ES2507145T3 (enExample)
HR (1) HRP20140887T1 (enExample)
IL (1) IL216369B (enExample)
PL (1) PL2430452T3 (enExample)
PT (1) PT2430452E (enExample)
SI (1) SI2430452T1 (enExample)
SM (1) SMT201400177B (enExample)
WO (1) WO2010132817A1 (enExample)

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PT2430452E (pt) 2009-05-14 2014-09-30 Univ Arizona State Diagnóstico e tratamentos de carcinoma com base no genótipo odc1
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LT2912193T (lt) * 2012-10-29 2018-12-27 Arizona Board Of Regents On Behalf Of University Of Arizona Prognozuojami žymenys, skirti vėžio terapijoms poliamino inhibitoriumi
WO2015195120A1 (en) * 2014-06-18 2015-12-23 Arizona Board Of Regents On Behalf Of University Of Arizona Carcinoma diagnosis and treatment based on odc1 genotype
US20190046484A1 (en) * 2015-02-12 2019-02-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating neuroblastoma
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CN114096240A (zh) 2019-05-17 2022-02-25 癌症预防制药股份有限公司 用于治疗家族性腺瘤性息肉病的方法

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US9937141B2 (en) 2018-04-10
CN102483415A (zh) 2012-05-30
CA2761946A1 (en) 2010-11-18
US8329636B2 (en) 2012-12-11
ES2507145T3 (es) 2014-10-14
EP2430452B1 (en) 2014-06-25
US20190038584A1 (en) 2019-02-07
US20100317708A1 (en) 2010-12-16
AU2010248803A1 (en) 2011-12-01
IL216369A0 (en) 2012-01-31
US9121852B2 (en) 2015-09-01
EP2430452A1 (en) 2012-03-21
HRP20140887T1 (hr) 2014-11-21
EP2430452A4 (en) 2013-03-06
US20160213634A1 (en) 2016-07-28
JP2016074672A (ja) 2016-05-12
SI2430452T1 (sl) 2014-11-28
CN102483415B (zh) 2015-09-09
US20130164751A1 (en) 2013-06-27
PL2430452T3 (pl) 2014-12-31
SMT201400177B (it) 2015-01-15
IL216369B (en) 2018-07-31
DK2430452T3 (da) 2014-10-06
HK1171082A1 (en) 2013-03-15
AU2010248803B2 (en) 2014-05-29
PT2430452E (pt) 2014-09-30
WO2010132817A1 (en) 2010-11-18
JP2012526852A (ja) 2012-11-01

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