JP6077710B2 - がん療法のためのリポソームシスプラチン組成物 - Google Patents

がん療法のためのリポソームシスプラチン組成物 Download PDF

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Publication number
JP6077710B2
JP6077710B2 JP2016502107A JP2016502107A JP6077710B2 JP 6077710 B2 JP6077710 B2 JP 6077710B2 JP 2016502107 A JP2016502107 A JP 2016502107A JP 2016502107 A JP2016502107 A JP 2016502107A JP 6077710 B2 JP6077710 B2 JP 6077710B2
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Japan
Prior art keywords
mol
composition
lipid
cisplatin
peg
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Expired - Fee Related
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JP2016502107A
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English (en)
Japanese (ja)
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JP2016513651A (ja
JP2016513651A5 (enExample
Inventor
ウィリアム マッギー，
ウィリアム マッギー，
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Mallinckrodt Inc
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Mallinckrodt Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
JP2016502107A 2013-03-13 2014-03-13 がん療法のためのリポソームシスプラチン組成物 Expired - Fee Related JP6077710B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780272P 2013-03-13 2013-03-13
US61/780,272 2013-03-13
PCT/US2014/026341 WO2014160337A1 (en) 2013-03-13 2014-03-13 Liposomal cisplatin compositions for cancer therapy

Publications (3)

Publication Number Publication Date
JP2016513651A JP2016513651A (ja) 2016-05-16
JP2016513651A5 JP2016513651A5 (enExample) 2016-12-22
JP6077710B2 true JP6077710B2 (ja) 2017-02-08

Family

ID=50439522

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016502107A Expired - Fee Related JP6077710B2 (ja) 2013-03-13 2014-03-13 がん療法のためのリポソームシスプラチン組成物

Country Status (8)

Country Link
US (2) US10039716B2 (enExample)
EP (1) EP2968142A1 (enExample)
JP (1) JP6077710B2 (enExample)
CN (1) CN105209017A (enExample)
BR (1) BR112015022415A2 (enExample)
CA (1) CA2903254C (enExample)
MX (1) MX2015012199A (enExample)
WO (1) WO2014160337A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150063533A (ko) * 2012-10-01 2015-06-09 헤이신 엘티디. 토출 시스템

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016141161A1 (en) * 2015-03-03 2016-09-09 Cureport, Inc. Dual loaded liposomal pharmaceutical formulations
WO2016141167A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Combination liposomal pharmaceutical formulations
US20170049701A1 (en) * 2015-08-05 2017-02-23 Steven M. Kushner Clustoidal multilamellar soy lecithin phospholipid structures for transdermal, transmucosal, or oral delivery, improved intestinal absorption, and improved bioavailability of nutrients
WO2017053464A1 (en) * 2015-09-21 2017-03-30 Mallinckrodt Llc Improved stability of liposome formulations and uses thereof
PE20181445A1 (es) * 2016-01-07 2018-09-12 Univ Western Health Sciences Formulaciones para el tratamiento del cancer de vejiga
WO2017142876A1 (en) 2016-02-15 2017-08-24 University Of Georgia Research Foundation, Inc. lPA-3-LOADED LIPOSOMES AND METHODS OF USE THEREOF
AU2017268175B2 (en) 2016-05-16 2023-02-23 Access To Advanced Health Institute PEGylated liposomes and methods of use
SG10202107836SA (en) * 2017-01-18 2021-08-30 Temasek Life Sciences Laboratory Ltd Hyperstabilized liposomes increase targeting of mitotic cells
WO2019094648A1 (en) 2017-11-08 2019-05-16 L.E.A.F. Holdings Group Llc Platinum complexes and uses thereof
ES2998498T3 (en) 2020-03-10 2025-02-20 Univ Chung Yuan Christian Liposome composition and preparation method thereof
TW202345843A (zh) * 2022-04-06 2023-12-01 財團法人國家衛生研究院 脂質奈米顆粒及脂質體

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843473A (en) * 1989-10-20 1998-12-01 Sequus Pharmaceuticals, Inc. Method of treatment of infected tissues
US20020009488A1 (en) * 1995-05-03 2002-01-24 Polymasc Pharmaceuticals Plc Tissue entrapment
WO1998007409A1 (en) * 1996-08-23 1998-02-26 Sequus Pharmaceuticals, Inc. Liposomes containing a cisplatin compound
BR9815445A (pt) 1997-02-05 2001-09-25 Pharmacia & Upjohn Spa Complexos lipìdicos e lipossomas de complexos de platina altamente insolúveis
ES2236181T3 (es) 2000-01-28 2005-07-16 Alza Corporation Liposomas que contienen un compuesto atrapado en una solucion supersaturada.
WO2002036073A2 (en) * 2000-11-02 2002-05-10 Smithkline Beecham Corporation Receptor antagonist-lipid conjugates and delivery vehicles containing same
EP1448165B1 (en) * 2001-11-13 2007-09-19 Celator Pharmaceuticals, Inc. Lipid carrier compositions and methods for improved drug retention
EP1674081A1 (de) * 2004-12-23 2006-06-28 KTB Tumorforschungsgesellschaft mbH Herstellung von lipidbasierten Nanopartikeln unter Einsatz einer dualen asymmetrischen Zentrifuge
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
EP1716870A1 (en) * 2005-04-29 2006-11-02 Bracco Imaging S.p.A. MRI contrast agents endowed with concentration independent responsiveness
US20100034874A1 (en) 2006-12-08 2010-02-11 Katayama Chemical Industries Co., Ltd. Liposome encapsulating ammine-platinum complex at high concentration, and method for production of the liposome

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150063533A (ko) * 2012-10-01 2015-06-09 헤이신 엘티디. 토출 시스템
KR102079414B1 (ko) 2012-10-01 2020-02-19 헤이신 엘티디. 토출 시스템

Also Published As

Publication number Publication date
US20140271821A1 (en) 2014-09-18
WO2014160337A1 (en) 2014-10-02
MX2015012199A (es) 2015-11-30
US10039716B2 (en) 2018-08-07
US20180318219A1 (en) 2018-11-08
JP2016513651A (ja) 2016-05-16
CA2903254C (en) 2019-04-09
US10383823B2 (en) 2019-08-20
CA2903254A1 (en) 2014-10-02
EP2968142A1 (en) 2016-01-20
BR112015022415A2 (pt) 2017-07-18
CN105209017A (zh) 2015-12-30

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