JP6077710B2 - がん療法のためのリポソームシスプラチン組成物 - Google Patents

がん療法のためのリポソームシスプラチン組成物 Download PDF

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Publication number
JP6077710B2
JP6077710B2 JP2016502107A JP2016502107A JP6077710B2 JP 6077710 B2 JP6077710 B2 JP 6077710B2 JP 2016502107 A JP2016502107 A JP 2016502107A JP 2016502107 A JP2016502107 A JP 2016502107A JP 6077710 B2 JP6077710 B2 JP 6077710B2
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Japan
Prior art keywords
mol
composition
lipid
cisplatin
peg
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Expired - Fee Related
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JP2016502107A
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English (en)
Japanese (ja)
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JP2016513651A (ja
JP2016513651A5 (cg-RX-API-DMAC7.html
Inventor
ウィリアム マッギー，
ウィリアム マッギー，
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Mallinckrodt Inc
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Mallinckrodt Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
JP2016502107A 2013-03-13 2014-03-13 がん療法のためのリポソームシスプラチン組成物 Expired - Fee Related JP6077710B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780272P 2013-03-13 2013-03-13
US61/780,272 2013-03-13
PCT/US2014/026341 WO2014160337A1 (en) 2013-03-13 2014-03-13 Liposomal cisplatin compositions for cancer therapy

Publications (3)

Publication Number Publication Date
JP2016513651A JP2016513651A (ja) 2016-05-16
JP2016513651A5 JP2016513651A5 (cg-RX-API-DMAC7.html) 2016-12-22
JP6077710B2 true JP6077710B2 (ja) 2017-02-08

Family

ID=50439522

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016502107A Expired - Fee Related JP6077710B2 (ja) 2013-03-13 2014-03-13 がん療法のためのリポソームシスプラチン組成物

Country Status (8)

Country Link
US (2) US10039716B2 (cg-RX-API-DMAC7.html)
EP (1) EP2968142A1 (cg-RX-API-DMAC7.html)
JP (1) JP6077710B2 (cg-RX-API-DMAC7.html)
CN (1) CN105209017A (cg-RX-API-DMAC7.html)
BR (1) BR112015022415A2 (cg-RX-API-DMAC7.html)
CA (1) CA2903254C (cg-RX-API-DMAC7.html)
MX (1) MX2015012199A (cg-RX-API-DMAC7.html)
WO (1) WO2014160337A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150063533A (ko) * 2012-10-01 2015-06-09 헤이신 엘티디. 토출 시스템

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016141167A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Combination liposomal pharmaceutical formulations
US10736845B2 (en) * 2015-03-03 2020-08-11 Cureport Inc. Dual loaded liposomal pharmaceutical formulations
US20170049701A1 (en) * 2015-08-05 2017-02-23 Steven M. Kushner Clustoidal multilamellar soy lecithin phospholipid structures for transdermal, transmucosal, or oral delivery, improved intestinal absorption, and improved bioavailability of nutrients
EP3352733A1 (en) * 2015-09-21 2018-08-01 Mallinckrodt LLC Improved stability of liposome formulations and uses thereof
SG11201805594PA (en) * 2016-01-07 2018-07-30 Univ Western Health Sciences Formulations for treating bladder cancer
EP3416623B1 (en) 2016-02-15 2021-08-11 University of Georgia Research Foundation, Inc. Ipa-3-loaded liposomes and methods of use thereof
US11266602B2 (en) * 2016-05-16 2022-03-08 Infectious Disease Research Institute PEGylated liposomes and methods of use
CN110381922A (zh) * 2017-01-18 2019-10-25 淡马锡生命科学研究院有限公司 超稳定脂质体增加对有丝分裂细胞的靶向作用
US20190231690A1 (en) * 2017-11-08 2019-08-01 L.E.A.F. Holdings Group Llc Platinum complexes and uses thereof
EP4117686B1 (en) 2020-03-10 2024-12-04 Chung Yuan Christian University Liposome composition and preparation method thereof
TW202345843A (zh) * 2022-04-06 2023-12-01 財團法人國家衛生研究院 脂質奈米顆粒及脂質體

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843473A (en) * 1989-10-20 1998-12-01 Sequus Pharmaceuticals, Inc. Method of treatment of infected tissues
US20020009488A1 (en) * 1995-05-03 2002-01-24 Polymasc Pharmaceuticals Plc Tissue entrapment
EP0929293B1 (en) 1996-08-23 2003-10-22 Sequus Pharmaceuticals, Inc. Liposomes containing a cisplatin compound
PT975329E (pt) 1997-02-05 2005-03-31 Upjohn Co Complexos de lipidos e lipossomas de complexos de platina altamente insoluveis
MXPA02007320A (es) * 2000-01-28 2004-07-30 Alza Corp Liposomas conteniendo un compuesto atrapado en solucion supersaturada.
EP1341497A4 (en) * 2000-11-02 2005-10-19 Smithkline Beecham Corp RECEPTOR-LIPID ANTAGONIST CONJUGATES AND DELIVERY VEHICLES CONTAINING THE SAME
ES2290333T3 (es) * 2001-11-13 2008-02-16 Celator Pharmaceuticals, Inc. Composiciones de vehiculos lipidicos y metodos para la retencion mejorada de farmacos.
EP1674081A1 (de) * 2004-12-23 2006-06-28 KTB Tumorforschungsgesellschaft mbH Herstellung von lipidbasierten Nanopartikeln unter Einsatz einer dualen asymmetrischen Zentrifuge
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
EP1716870A1 (en) * 2005-04-29 2006-11-02 Bracco Imaging S.p.A. MRI contrast agents endowed with concentration independent responsiveness
US20100034874A1 (en) 2006-12-08 2010-02-11 Katayama Chemical Industries Co., Ltd. Liposome encapsulating ammine-platinum complex at high concentration, and method for production of the liposome

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150063533A (ko) * 2012-10-01 2015-06-09 헤이신 엘티디. 토출 시스템
KR102079414B1 (ko) 2012-10-01 2020-02-19 헤이신 엘티디. 토출 시스템

Also Published As

Publication number Publication date
US10039716B2 (en) 2018-08-07
CA2903254A1 (en) 2014-10-02
JP2016513651A (ja) 2016-05-16
CN105209017A (zh) 2015-12-30
US20180318219A1 (en) 2018-11-08
US10383823B2 (en) 2019-08-20
CA2903254C (en) 2019-04-09
MX2015012199A (es) 2015-11-30
EP2968142A1 (en) 2016-01-20
WO2014160337A1 (en) 2014-10-02
BR112015022415A2 (pt) 2017-07-18
US20140271821A1 (en) 2014-09-18

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