JP6071554B2 - イヌ科動物の眼の健康を維持するため、及び眼の病気を改善するための方法 - Google Patents
イヌ科動物の眼の健康を維持するため、及び眼の病気を改善するための方法 Download PDFInfo
- Publication number
- JP6071554B2 JP6071554B2 JP2012536786A JP2012536786A JP6071554B2 JP 6071554 B2 JP6071554 B2 JP 6071554B2 JP 2012536786 A JP2012536786 A JP 2012536786A JP 2012536786 A JP2012536786 A JP 2012536786A JP 6071554 B2 JP6071554 B2 JP 6071554B2
- Authority
- JP
- Japan
- Prior art keywords
- carotene
- eye
- canine
- canines
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
[0013]用語「放射線」とは、カロテンにより部分的に又は完全に吸収される波長を有する電磁波を意味する。一般的に、カロテン、例えばβ−カロテンは、約350〜約550ナノメータ(nm)の波長を有する電磁波を吸収し、最大吸収は約400〜約500nmで生ずる。
本発明
[0054]眼のサンプルはイヌ7匹から収集された。眼球は検視時に死亡1時間以内に摘出され、個別容器内に4℃で保管され、1日以内に解剖するために氷水上で保管された。眼は水晶体を取り出すために切開された。水晶体は2層に分離された:(1)外側の軟性の皮質層/上皮層、及び(2)内側の硬質の核層。これらの層は、Craft NE、Haitema TB、Garnett KM、Fitch KA、Dorey CK.、Carotenoid,tocopherol,and retinol concentrations in elderly human brain、J Nutr.Health Aging、2004年;第8巻:156〜62頁、に記載されている標準的な手順に従い、カロテノイド、ビタミンC、及びビタミンEについて分析された。結果を表1に掲載する。
Claims (10)
- イヌ科動物におけるクラウディ・アイ(cloudy eye)を予防又は改善するための組成物であって、
カロテンを眼組織内に蓄積する量で含み、
経口投与され、
前記カロテンが、β−カロテンである、組成物。 - 前記カロテンが、眼の皮質組織内、眼の核組織内、又はその両方に蓄積している、請求項1に記載の組成物。
- 前記カロテンが、0.1〜5000mgの量でイヌ科動物に投与される、請求項1に記載の組成物。
- 前記カロテンが、1日当たり0.1〜500mgの量でイヌ科動物に投与される、請求項1に記載の組成物。
- 前記イヌ科動物が、イヌである、請求項1に記載の組成物。
- 前記カロテンが、長期間定期的にイヌ科動物に投与される、請求項1に記載の組成物。
- 前記カロテンが、イヌ科動物に毎日投与される、請求項1に記載の組成物。
- 前記イヌ科動物が、高齢のイヌ科動物である、請求項1に記載の組成物。
- 前記カロテンを、クラウディ・アイ(cloudy eye)を予防又は改善するのに有効な量の1つ又は複数の眼科薬と併用して、投与するための、請求項1に記載の組成物。
- イヌ科動物におけるクラウディ・アイ(cloudy eye)を予防又は改善するための薬剤を製造するためのカロテンの使用であって、
前記薬剤は経口投与され、
前記カロテンが、β−カロテンである、使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28017509P | 2009-10-30 | 2009-10-30 | |
US61/280,175 | 2009-10-30 | ||
PCT/US2010/002815 WO2011059474A1 (en) | 2009-10-30 | 2010-10-22 | Methods for maintaining eye health and ameliorating opthalmic maladies in canines |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2013509407A JP2013509407A (ja) | 2013-03-14 |
JP2013509407A5 JP2013509407A5 (ja) | 2015-08-27 |
JP6071554B2 true JP6071554B2 (ja) | 2017-02-01 |
Family
ID=43991896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012536786A Expired - Fee Related JP6071554B2 (ja) | 2009-10-30 | 2010-10-22 | イヌ科動物の眼の健康を維持するため、及び眼の病気を改善するための方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20120270954A1 (ja) |
EP (1) | EP2493293B1 (ja) |
JP (1) | JP6071554B2 (ja) |
CN (1) | CN102686107A (ja) |
AU (1) | AU2010318687B2 (ja) |
BR (1) | BR112012010179A2 (ja) |
CA (1) | CA2778229A1 (ja) |
ES (1) | ES2566652T3 (ja) |
IN (1) | IN2012DN03631A (ja) |
MX (1) | MX2012004777A (ja) |
RU (1) | RU2012122169A (ja) |
WO (1) | WO2011059474A1 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6026719B2 (ja) * | 2010-08-31 | 2016-11-16 | 株式会社ダイセル | 視機能予防・改善剤 |
WO2013043366A1 (en) * | 2011-09-20 | 2013-03-28 | Nestec S.A. | Methods and compositions for improving visual function and eye health |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2094060C1 (ru) * | 1994-03-22 | 1997-10-27 | Уфимский научно-исследовательский институт глазных болезней | Глазная мазь |
NZ527924A (en) * | 1999-01-29 | 2005-01-28 | Mars Uk Ltd | Antioxidant compositions and methods for companion animals |
US20020110604A1 (en) * | 2000-08-11 | 2002-08-15 | Ashni Naturaceuticals, Inc. | Composition exhibiting synergistic antioxidant activity |
WO2002082093A2 (en) * | 2001-04-02 | 2002-10-17 | Tufts University | Methods to measure lipid antioxidant activity |
MXPA04011416A (es) | 2002-05-17 | 2005-09-30 | Othera Pharmaceuticals Inc | Mejora del desarrollo de las cataratas y otras enfermedades oftalmicas. |
NZ553731A (en) | 2002-05-28 | 2007-07-27 | Altana Pharma Ag | Topically applicable pharmaceutical preparation of roflumilast and liquid paraffin |
CA2556223A1 (en) * | 2004-03-10 | 2005-09-22 | Trustees Of Tufts College | Synergistic effect of compositions comprising carotenoids selected from lutein, beta-carotene and lycopene |
JP2008515778A (ja) * | 2004-08-18 | 2008-05-15 | シリオン セラピューティクス, インコーポレイテッド | 眼の状態を13−シス−レチニル誘導体で処置するための組み合わせ方法、組成物および治療 |
WO2006116755A2 (en) * | 2005-04-28 | 2006-11-02 | Trustees Of Tufts College | Synergitic effects of docosahexaenoic acid (dha) and carotenoid absorption of cognitive function |
EP2023945B1 (en) * | 2006-06-08 | 2019-08-07 | IAMS Europe B.V. | Composition for improving eye health |
US8158667B2 (en) | 2006-08-21 | 2012-04-17 | Kador Peter F | Topical treatment of cataracts in dogs |
CN101903045B (zh) | 2007-10-19 | 2013-03-13 | 株式会社·R-技术上野 | 用于治疗白内障的药物组合物 |
CN101939411A (zh) * | 2008-02-06 | 2011-01-05 | 宝洁公司 | 用于提高呼吸病症免疫应答的组合物、方法和试剂盒 |
-
2010
- 2010-10-22 JP JP2012536786A patent/JP6071554B2/ja not_active Expired - Fee Related
- 2010-10-22 BR BR112012010179A patent/BR112012010179A2/pt not_active Application Discontinuation
- 2010-10-22 US US13/503,953 patent/US20120270954A1/en not_active Abandoned
- 2010-10-22 ES ES10830307.4T patent/ES2566652T3/es active Active
- 2010-10-22 EP EP10830307.4A patent/EP2493293B1/en not_active Not-in-force
- 2010-10-22 CA CA2778229A patent/CA2778229A1/en not_active Abandoned
- 2010-10-22 MX MX2012004777A patent/MX2012004777A/es active IP Right Grant
- 2010-10-22 CN CN2010800595322A patent/CN102686107A/zh active Pending
- 2010-10-22 WO PCT/US2010/002815 patent/WO2011059474A1/en active Application Filing
- 2010-10-22 RU RU2012122169/13A patent/RU2012122169A/ru unknown
- 2010-10-22 AU AU2010318687A patent/AU2010318687B2/en not_active Ceased
- 2010-10-22 IN IN3631DEN2012 patent/IN2012DN03631A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN102686107A (zh) | 2012-09-19 |
JP2013509407A (ja) | 2013-03-14 |
EP2493293A1 (en) | 2012-09-05 |
AU2010318687A1 (en) | 2012-05-24 |
AU2010318687B2 (en) | 2016-02-25 |
RU2012122169A (ru) | 2013-12-10 |
US20120270954A1 (en) | 2012-10-25 |
EP2493293A4 (en) | 2013-03-20 |
EP2493293B1 (en) | 2016-03-02 |
CA2778229A1 (en) | 2011-05-19 |
IN2012DN03631A (ja) | 2015-06-26 |
WO2011059474A1 (en) | 2011-05-19 |
BR112012010179A2 (pt) | 2015-09-29 |
MX2012004777A (es) | 2012-06-01 |
ES2566652T3 (es) | 2016-04-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5138380B2 (ja) | 動物における免疫応答を増大させる方法 | |
JP5785355B2 (ja) | 動物における生体異物物質の肝臓クリアランスを改良する方法 | |
RU2605330C2 (ru) | Способы и композиции, подходящие для укрепления здоровья кожи | |
RU2597793C2 (ru) | Способы и композиции для лечения, ослабления или предотвращения ухудшения зрительной системы животных | |
CA2592301A1 (en) | Use of antioxidants to promote oral health in companion animals | |
US20140170247A1 (en) | Emulsion of Carotenoids and Ocular Antioxidants | |
AU2008307494A1 (en) | Compositions and methods for enhancing cognitive function | |
JP2014501759A (ja) | 動物の血糖管理に適した方法及び組成物 | |
JP6071554B2 (ja) | イヌ科動物の眼の健康を維持するため、及び眼の病気を改善するための方法 | |
AU2011338846B2 (en) | Methods and compositions useful for promoting sleep in animals | |
ES2761826T3 (es) | Composiciones que contienen triglicéridos de cadena media para su uso en el tratamiento de la epilepsia | |
JP2013509407A5 (ja) | ||
WO2014062552A1 (en) | Methods for maintaining eye health and ameliorating opthalmic maladies in animals | |
Nootropic | Vision Enhancer Ingredient Guide–What Works & What Doesn’t? |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20131018 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20131018 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140902 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20141202 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20150303 |
|
A524 | Written submission of copy of amendment under article 19 pct |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20150703 |
|
A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20150714 |
|
A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20150814 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160930 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20161227 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6071554 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |